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The map label for this gene is virB [H]

Identifier: 189353519

GI number: 189353519

Start: 1742202

End: 1743005

Strand: Direct

Name: virB [H]

Synonym: BMULJ_04763

Alternate gene names: 189353519

Gene position: 1742202-1743005 (Clockwise)

Preceding gene: 189353518

Following gene: 189353520

Centisome position: 70.44

GC content: 72.39

Gene sequence:

>804_bases
ATGAACGCGCGCCGCCTGCACAGCGCAGCCGCCGCGCTATGCGCGACGGTCGCGCTCGTCGCACTGACGTTCGCCTGCGT
GCCGCCGCGCGTCGCGCATGCGCGCGCGTCGTCGGGCAGCGGCGGTTTCGCGCAACTCGCGCGCGCCTGCGCGCCGAACG
TCGATCCCGACACGCTCGCCGCGCTGGTGCGCACCGAATCGGGCTTCAATCCCTATGCGATCGGCGTGGTCGGCGGCCAT
CTGACGCGCCAGCCGGCATCGCTCGACGAGGCGCGCGCGACCGTGCGCGCGCTGGCCGCGCGCGGCTTCAGCTACAGCGT
CGGTCTTGCCCAGGTGAACGAGCGCAATTTCGCGAAATACGGGCTCGACGAAGCGACGATGTTCGAACCGTGCCGCAATC
TGCAGGCCGGCGGCGCGATCCTGACCGAGTGCTTCGCGCGCTCGTCCGGCACCGGCCGCCCCGCGCAGGCCGCGTTGCGC
GCCGCGCTGTCGTGCTACTACAGCGGCAATTTCACGACCGGATTCTCGAGCGGCTACGTGAGCCGTGTCGTCGCGAGCGC
ACAGCGCAATGCGCGCGAAGGCGGCGTCGAACCGATCCCCGTCGTGCGCGACGTGCCGCTGCCCGCGCGCCAGCGGCGCA
TGGATGCGGCCGCAACGACACCGCCCGAGCATGCGCGGCGGCTCGCCTCGCCGGCGGCGTCCGCAGACGCGCCGTCGTGC
CATGCACGGCCCGTCGTGATGATGTGCCGCGGGCTGCCGGCGAGCCAGGCGAAGCGGCTTTGCGTGCGGTGTCTCGATCA
ATGA

Upstream 100 bases:

>100_bases
CGATCTCGGTGCCGTTCAAGCTGCTGCTGTTCGTCGCGCTCGATGGCTGGTCGCTGCTCGTGCACGGGCTCGTGCTGTCG
TACCGCGTCGCGGGGGCGGG

Downstream 100 bases:

>100_bases
CCGAATGATCGCGCGCGGCACGACGGCTGCATGCGCGCGCGATTTTCCGGGGCGAACGACGCGGTGCAACAGCGCGGCGG
TGCCGCCGCGCGCCGCGCCC

Product: type IV secretion system protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 267; Mature: 267

Protein sequence:

>267_residues
MNARRLHSAAAALCATVALVALTFACVPPRVAHARASSGSGGFAQLARACAPNVDPDTLAALVRTESGFNPYAIGVVGGH
LTRQPASLDEARATVRALAARGFSYSVGLAQVNERNFAKYGLDEATMFEPCRNLQAGGAILTECFARSSGTGRPAQAALR
AALSCYYSGNFTTGFSSGYVSRVVASAQRNAREGGVEPIPVVRDVPLPARQRRMDAAATTPPEHARRLASPAASADAPSC
HARPVVMMCRGLPASQAKRLCVRCLDQ

Sequences:

>Translated_267_residues
MNARRLHSAAAALCATVALVALTFACVPPRVAHARASSGSGGFAQLARACAPNVDPDTLAALVRTESGFNPYAIGVVGGH
LTRQPASLDEARATVRALAARGFSYSVGLAQVNERNFAKYGLDEATMFEPCRNLQAGGAILTECFARSSGTGRPAQAALR
AALSCYYSGNFTTGFSSGYVSRVVASAQRNAREGGVEPIPVVRDVPLPARQRRMDAAATTPPEHARRLASPAASADAPSC
HARPVVMMCRGLPASQAKRLCVRCLDQ
>Mature_267_residues
MNARRLHSAAAALCATVALVALTFACVPPRVAHARASSGSGGFAQLARACAPNVDPDTLAALVRTESGFNPYAIGVVGGH
LTRQPASLDEARATVRALAARGFSYSVGLAQVNERNFAKYGLDEATMFEPCRNLQAGGAILTECFARSSGTGRPAQAALR
AALSCYYSGNFTTGFSSGYVSRVVASAQRNAREGGVEPIPVVRDVPLPARQRRMDAAATTPPEHARRLASPAASADAPSC
HARPVVMMCRGLPASQAKRLCVRCLDQ

Specific function: The virB operon is essential for intracellular survival and is not involved in the invasion process. Constitutes a major determinant of virulence in mice [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the virb1 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008258 [H]

Pfam domain/function: PF01464 SLT [H]

EC number: NA

Molecular weight: Translated: 27912; Mature: 27912

Theoretical pI: Translated: 9.86; Mature: 9.86

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
3.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNARRLHSAAAALCATVALVALTFACVPPRVAHARASSGSGGFAQLARACAPNVDPDTLA
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCHHHHHHHHCCCCCHHHHH
ALVRTESGFNPYAIGVVGGHLTRQPASLDEARATVRALAARGFSYSVGLAQVNERNFAKY
HHHHHCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCEECCHHHHCCCHHHHH
GLDEATMFEPCRNLQAGGAILTECFARSSGTGRPAQAALRAALSCYYSGNFTTGFSSGYV
CCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHH
SRVVASAQRNAREGGVEPIPVVRDVPLPARQRRMDAAATTPPEHARRLASPAASADAPSC
HHHHHHHHHHHHHCCCCCCCCEECCCCCHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCC
HARPVVMMCRGLPASQAKRLCVRCLDQ
CCCHHHHHHCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MNARRLHSAAAALCATVALVALTFACVPPRVAHARASSGSGGFAQLARACAPNVDPDTLA
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCHHHHHHHHCCCCCHHHHH
ALVRTESGFNPYAIGVVGGHLTRQPASLDEARATVRALAARGFSYSVGLAQVNERNFAKY
HHHHHCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCEECCHHHHCCCHHHHH
GLDEATMFEPCRNLQAGGAILTECFARSSGTGRPAQAALRAALSCYYSGNFTTGFSSGYV
CCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHH
SRVVASAQRNAREGGVEPIPVVRDVPLPARQRRMDAAATTPPEHARRLASPAASADAPSC
HHHHHHHHHHHHHCCCCCCCCEECCCCCHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCC
HARPVVMMCRGLPASQAKRLCVRCLDQ
CCCHHHHHHCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10940027 [H]