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The map label for this gene is bepF [H]

Identifier: 189353331

GI number: 189353331

Start: 1572327

End: 1573529

Strand: Reverse

Name: bepF [H]

Synonym: BMULJ_04571

Alternate gene names: 189353331

Gene position: 1573529-1572327 (Counterclockwise)

Preceding gene: 189353333

Following gene: 189353330

Centisome position: 63.62

GC content: 70.16

Gene sequence:

>1203_bases
ATGCTCTCCCTCTCTTTCCGCAGGACCTCGCCGTTGGGCGCGGCCTGTGTCCTGCTGCTGGCGCTGTCCGGCTGTCACGA
CGGCCAGGGCGACGCGCCGAGCGCGCCGTTGCCCGAGGTCGGGGTTGCGACCGTCGTTCCCCGTACCGTGAGGATCGCGG
ATGAATTCAACGGCCGCGTCGAAGCCGTCGATGCGGTCGAATTGCGGCCGCGCGTGAGCGGCTATCTGCAACGGATCCGA
TACAAGGAAGGCGATCTCGTCGCGCAGGGCGCGGTGCTGTTCGAGATCGATCCGCGCCCTTACCGGATCGCGCTCGATCG
CGCGATCGCGCAGCAGCAGCGCGCGCGTGCCGCCGAGCACCTCGCGCGCGTGCAGCTGCAGCGCGTGCAGACGCTGATCG
ACGCGCATGCGACATCGCAGGAAGAACTCGACAATGCGCGTGCGGCGGCCGAGCAGGCGCGCGCCGATTTGCAGGCGGCC
GATGCTGCGGTCGCCGACGCGAAGCTGAACCTCGGCTTCACCGAAGTGCGCGCGCCGATCGCGGGCCGCGTCGGCCGTGC
GCTCGCGACAGCCGGCAATCTCGCGCGTGCGGACGACACGCTGCTCACGACCGTCGTATCGCAGGATCCCGTCTACGTGT
ACTTCGACTGCGACGAACAGAGCTATCTGCGCTACAACGCGCAGCGCGCGGATCCGGCGCATCGTGCGATCGGCGCCGAT
CCCGTGCGCGTCGGCCTCGCGAACGAAACGGGCTTCCCGCACGCGGGCACCGTCGACTTCCTCGACAACCGGCTCGATCC
GCAAACCGGCACGATCCGCGCGCGCGTGCGGCTGCCGAATGCGGACCACACCTTCACGCCGGGGCTGTACGCACGCGTGC
AGCTCGTCAGCGGGCGCGAGCGGAGCGCACTGCTCGTCGACGACAAGGCCGTGCTGACCGATCAGGACCGCAAGTACGTC
TACGTGATCGGCCCCGGCGACAAGGCGCTGCGCCGCGACGTGACGATCGGCCGCGATCTCGACGGCCAGCGGATCGTCGA
GAAGGGGCTGAATGCGGGCGATCGCGTCGTCGTCGACGGCGTGCAGCGCATCTACTATCCGGGCGCGCAGGTCAAGCCGA
AGCCGCAACCGGCGCGCGCCGATGTGCAACCGGGCGCCGCCGCGCAGGCCGTCGCCGATGCCGGCGCGCCGGCCGCGCAA
TAA

Upstream 100 bases:

>100_bases
CGGAACTTCCTGGATACCCATGATGCCCTCCGGGAAAGCTTGACTTGAAGTTAACTTGAACTTTTAAGCTACGCGGCAGT
TTAACCCGTCGCGAGGCAAC

Downstream 100 bases:

>100_bases
CGGGAGGCATGCGATGGATTTCTCCCGTTTCTTCATCGACCGGCCGATCTTCGCGGTCGTGCTGTCGATCGTGATCTTCG
CGCTCGGTCTGATCGCGATC

Product: HlyD family secretion protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 400; Mature: 400

Protein sequence:

>400_residues
MLSLSFRRTSPLGAACVLLLALSGCHDGQGDAPSAPLPEVGVATVVPRTVRIADEFNGRVEAVDAVELRPRVSGYLQRIR
YKEGDLVAQGAVLFEIDPRPYRIALDRAIAQQQRARAAEHLARVQLQRVQTLIDAHATSQEELDNARAAAEQARADLQAA
DAAVADAKLNLGFTEVRAPIAGRVGRALATAGNLARADDTLLTTVVSQDPVYVYFDCDEQSYLRYNAQRADPAHRAIGAD
PVRVGLANETGFPHAGTVDFLDNRLDPQTGTIRARVRLPNADHTFTPGLYARVQLVSGRERSALLVDDKAVLTDQDRKYV
YVIGPGDKALRRDVTIGRDLDGQRIVEKGLNAGDRVVVDGVQRIYYPGAQVKPKPQPARADVQPGAAAQAVADAGAPAAQ

Sequences:

>Translated_400_residues
MLSLSFRRTSPLGAACVLLLALSGCHDGQGDAPSAPLPEVGVATVVPRTVRIADEFNGRVEAVDAVELRPRVSGYLQRIR
YKEGDLVAQGAVLFEIDPRPYRIALDRAIAQQQRARAAEHLARVQLQRVQTLIDAHATSQEELDNARAAAEQARADLQAA
DAAVADAKLNLGFTEVRAPIAGRVGRALATAGNLARADDTLLTTVVSQDPVYVYFDCDEQSYLRYNAQRADPAHRAIGAD
PVRVGLANETGFPHAGTVDFLDNRLDPQTGTIRARVRLPNADHTFTPGLYARVQLVSGRERSALLVDDKAVLTDQDRKYV
YVIGPGDKALRRDVTIGRDLDGQRIVEKGLNAGDRVVVDGVQRIYYPGAQVKPKPQPARADVQPGAAAQAVADAGAPAAQ
>Mature_400_residues
MLSLSFRRTSPLGAACVLLLALSGCHDGQGDAPSAPLPEVGVATVVPRTVRIADEFNGRVEAVDAVELRPRVSGYLQRIR
YKEGDLVAQGAVLFEIDPRPYRIALDRAIAQQQRARAAEHLARVQLQRVQTLIDAHATSQEELDNARAAAEQARADLQAA
DAAVADAKLNLGFTEVRAPIAGRVGRALATAGNLARADDTLLTTVVSQDPVYVYFDCDEQSYLRYNAQRADPAHRAIGAD
PVRVGLANETGFPHAGTVDFLDNRLDPQTGTIRARVRLPNADHTFTPGLYARVQLVSGRERSALLVDDKAVLTDQDRKYV
YVIGPGDKALRRDVTIGRDLDGQRIVEKGLNAGDRVVVDGVQRIYYPGAQVKPKPQPARADVQPGAAAQAVADAGAPAAQ

Specific function: May contribute to resistance to some drugs, such as deoxycholate, sodium dodecyl sulfate and nalidixic acid, in the absence of BepD and BepE [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1786668, Length=388, Percent_Identity=35.5670103092784, Blast_Score=196, Evalue=2e-51,
Organism=Escherichia coli, GI1789929, Length=346, Percent_Identity=32.0809248554913, Blast_Score=184, Evalue=1e-47,
Organism=Escherichia coli, GI1789665, Length=354, Percent_Identity=31.3559322033898, Blast_Score=159, Evalue=4e-40,
Organism=Escherichia coli, GI87082036, Length=343, Percent_Identity=30.6122448979592, Blast_Score=142, Evalue=5e-35,
Organism=Escherichia coli, GI87081796, Length=350, Percent_Identity=26.5714285714286, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1790519, Length=266, Percent_Identity=27.0676691729323, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI87081951, Length=172, Percent_Identity=31.9767441860465, Blast_Score=65, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 43008; Mature: 43008

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.2 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.2 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSLSFRRTSPLGAACVLLLALSGCHDGQGDAPSAPLPEVGVATVVPRTVRIADEFNGRV
CCEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHCCCEEEEEHHCCCEE
EAVDAVELRPRVSGYLQRIRYKEGDLVAQGAVLFEIDPRPYRIALDRAIAQQQRARAAEH
EEEEHHHHCHHHHHHHHHHHCCCCCEEECCEEEEEECCCCEEEHHHHHHHHHHHHHHHHH
LARVQLQRVQTLIDAHATSQEELDNARAAAEQARADLQAADAAVADAKLNLGFTEVRAPI
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCHHHHHCCH
AGRVGRALATAGNLARADDTLLTTVVSQDPVYVYFDCDEQSYLRYNAQRADPAHRAIGAD
HHHHHHHHHHCCCCCCCCCHHEEEEECCCCEEEEEECCCCCHHEECCCCCCHHHHHCCCC
PVRVGLANETGFPHAGTVDFLDNRLDPQTGTIRARVRLPNADHTFTPGLYARVQLVSGRE
CEEEEECCCCCCCCCCCHHHHHCCCCCCCCEEEEEEECCCCCCCCCCCCEEEEEEECCCC
RSALLVDDKAVLTDQDRKYVYVIGPGDKALRRDVTIGRDLDGQRIVEKGLNAGDRVVVDG
CCEEEECCCEEEECCCCEEEEEECCCCHHHHHCCCCCCCCCHHHHHHHCCCCCCEEEHCC
VQRIYYPGAQVKPKPQPARADVQPGAAAQAVADAGAPAAQ
HHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCC
>Mature Secondary Structure
MLSLSFRRTSPLGAACVLLLALSGCHDGQGDAPSAPLPEVGVATVVPRTVRIADEFNGRV
CCEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHCCCEEEEEHHCCCEE
EAVDAVELRPRVSGYLQRIRYKEGDLVAQGAVLFEIDPRPYRIALDRAIAQQQRARAAEH
EEEEHHHHCHHHHHHHHHHHCCCCCEEECCEEEEEECCCCEEEHHHHHHHHHHHHHHHHH
LARVQLQRVQTLIDAHATSQEELDNARAAAEQARADLQAADAAVADAKLNLGFTEVRAPI
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCHHHHHCCH
AGRVGRALATAGNLARADDTLLTTVVSQDPVYVYFDCDEQSYLRYNAQRADPAHRAIGAD
HHHHHHHHHHCCCCCCCCCHHEEEEECCCCEEEEEECCCCCHHEECCCCCCHHHHHCCCC
PVRVGLANETGFPHAGTVDFLDNRLDPQTGTIRARVRLPNADHTFTPGLYARVQLVSGRE
CEEEEECCCCCCCCCCCHHHHHCCCCCCCCEEEEEEECCCCCCCCCCCCEEEEEEECCCC
RSALLVDDKAVLTDQDRKYVYVIGPGDKALRRDVTIGRDLDGQRIVEKGLNAGDRVVVDG
CCEEEECCCEEEECCCCEEEEEECCCCHHHHHCCCCCCCCCHHHHHHHCCCCCCEEEHCC
VQRIYYPGAQVKPKPQPARADVQPGAAAQAVADAGAPAAQ
HHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12271122 [H]