BacMap

Definition	Burkholderia multivorans ATCC 17616 chromosome 2, complete genome.
Accession	NC_010805
Length	2,473,162

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The map label for this gene is fabG [H]

Identifier: 189353333

GI number: 189353333

Start: 1574128

End: 1574889

Strand: Reverse

Name: fabG [H]

Synonym: BMULJ_04573

Alternate gene names: 189353333

Gene position: 1574889-1574128 (Counterclockwise)

Preceding gene: 189353335

Following gene: 189353331

Centisome position: 63.68

GC content: 71.78

Gene sequence:

>762_bases
ATGACAGGTGTTGAACCGCAGCGCACGGCGCTGGTGACGGGCGGGTCGAGCGGGATCGGTTTCGCGATCGCGCGGCGCTT
GATCGACGATGGTTATCGCGTCGCGATCGTGGCGCGCGATGCGCAGCGGCTGGCAGCGTCGGTCGCGCAACTCGGCGACG
CGGCGTTCGGGCACGCGGCGGACCTCAGCGTGCGGCGCGATGCGGAAGCGGCCGTCGCCGCGATCGTCGCGCGCTGGCCG
TGCATCGACGTGCTGGTCAACAACGCGGGCCTGACGCGGCGCGTCAGCGCCGATACGCCGCTCGACGATGCCGAGGCGGC
ATGGGATGCGGTAATCGAAGCGAACCTGAAGAGCGCGTTCGTCACGACGCTGGCCGTGCTGCCGCATCTGGCCGCACATG
ATGCGCGCATCGTCAACGTCGGCTCGATCGCCGCGCGTGCGGGCAGCCTGCTGCCGGGCGGTCTCGCGTACGCGGCGGCG
AAGGCGGGCGTCGAAGGATTCACCGTCGCGCTCGCGCGCGAACTGGGGCCGCGCGGCGTCACGGTGAATACCGTCGCGCC
GGGCTATATCGCGGATACGCGCTTTTTCGGCGATGGTGGCGTCGCGTCGGACATCGCGGCGACCATCCGTGAGCAGACGC
CGGTCGGCCGCGCCGGGCAACCTGCCGATATCGCGGACGCGGTCGCCTGGCTCGCGAGCCCGCGCGCGGCGTTCGTCACG
GGCGCGACGATTGCGGTGAACGGCGGCTGGCGGGTCGGGTGA

Upstream 100 bases:

>100_bases
TTCCATGTATCAGTTGATCATCGAATTCGTATTTTATCTATCGCGCGGCGTCGACCAGACTTCCGGTGTCATTCATTGTC
GACATTCGGGAGGGCAGGTC

Downstream 100 bases:

>100_bases
CATGCCGGCCGGCGCCGGCCGTGATCCGCATCACGCACTTCATTCCGGAACGGCCGGCGGCGGATCGCCGAGCCAGCGCC
GCGCGCCGGGCCCGTTGCGG

Product: 3-oxoacyl-[acyl-carrier protein] reductase

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 253; Mature: 252

Protein sequence:

>253_residues
MTGVEPQRTALVTGGSSGIGFAIARRLIDDGYRVAIVARDAQRLAASVAQLGDAAFGHAADLSVRRDAEAAVAAIVARWP
CIDVLVNNAGLTRRVSADTPLDDAEAAWDAVIEANLKSAFVTTLAVLPHLAAHDARIVNVGSIAARAGSLLPGGLAYAAA
KAGVEGFTVALARELGPRGVTVNTVAPGYIADTRFFGDGGVASDIAATIREQTPVGRAGQPADIADAVAWLASPRAAFVT
GATIAVNGGWRVG

Sequences:

>Translated_253_residues
MTGVEPQRTALVTGGSSGIGFAIARRLIDDGYRVAIVARDAQRLAASVAQLGDAAFGHAADLSVRRDAEAAVAAIVARWP
CIDVLVNNAGLTRRVSADTPLDDAEAAWDAVIEANLKSAFVTTLAVLPHLAAHDARIVNVGSIAARAGSLLPGGLAYAAA
KAGVEGFTVALARELGPRGVTVNTVAPGYIADTRFFGDGGVASDIAATIREQTPVGRAGQPADIADAVAWLASPRAAFVT
GATIAVNGGWRVG
>Mature_252_residues
TGVEPQRTALVTGGSSGIGFAIARRLIDDGYRVAIVARDAQRLAASVAQLGDAAFGHAADLSVRRDAEAAVAAIVARWPC
IDVLVNNAGLTRRVSADTPLDDAEAAWDAVIEANLKSAFVTTLAVLPHLAAHDARIVNVGSIAARAGSLLPGGLAYAAAK
AGVEGFTVALARELGPRGVTVNTVAPGYIADTRFFGDGGVASDIAATIREQTPVGRAGQPADIADAVAWLASPRAAFVTG
ATIAVNGGWRVG

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=255, Percent_Identity=35.6862745098039, Blast_Score=124, Evalue=9e-29,
Organism=Homo sapiens, GI15277342, Length=258, Percent_Identity=37.5968992248062, Blast_Score=119, Evalue=2e-27,
Organism=Homo sapiens, GI5031737, Length=252, Percent_Identity=34.1269841269841, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI40254992, Length=249, Percent_Identity=30.1204819277108, Blast_Score=103, Evalue=1e-22,
Organism=Homo sapiens, GI126723750, Length=256, Percent_Identity=32.421875, Blast_Score=101, Evalue=7e-22,
Organism=Homo sapiens, GI19923817, Length=252, Percent_Identity=30.952380952381, Blast_Score=99, Evalue=3e-21,
Organism=Homo sapiens, GI59889578, Length=232, Percent_Identity=31.0344827586207, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI33667109, Length=191, Percent_Identity=35.6020942408377, Blast_Score=95, Evalue=8e-20,
Organism=Homo sapiens, GI10190704, Length=247, Percent_Identity=30.7692307692308, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI126723191, Length=191, Percent_Identity=35.0785340314136, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI4758504, Length=255, Percent_Identity=27.843137254902, Blast_Score=82, Evalue=3e-16,
Organism=Homo sapiens, GI109715829, Length=245, Percent_Identity=28.1632653061224, Blast_Score=78, Evalue=6e-15,
Organism=Homo sapiens, GI66933014, Length=174, Percent_Identity=29.8850574712644, Blast_Score=75, Evalue=4e-14,
Organism=Homo sapiens, GI7706318, Length=208, Percent_Identity=29.8076923076923, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI83715985, Length=258, Percent_Identity=26.3565891472868, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI150247226, Length=197, Percent_Identity=31.9796954314721, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI7705925, Length=247, Percent_Identity=29.1497975708502, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI1787335, Length=247, Percent_Identity=41.2955465587045, Blast_Score=138, Evalue=3e-34,
Organism=Escherichia coli, GI1789208, Length=247, Percent_Identity=34.8178137651822, Blast_Score=114, Evalue=8e-27,
Organism=Escherichia coli, GI2367175, Length=250, Percent_Identity=33.6, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1787820, Length=231, Percent_Identity=34.1991341991342, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI2367365, Length=248, Percent_Identity=34.6774193548387, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI87082160, Length=252, Percent_Identity=30.1587301587302, Blast_Score=100, Evalue=6e-23,
Organism=Escherichia coli, GI1790717, Length=254, Percent_Identity=31.1023622047244, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI87082100, Length=256, Percent_Identity=32.421875, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1789378, Length=251, Percent_Identity=33.0677290836653, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1788459, Length=252, Percent_Identity=30.5555555555556, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI1787905, Length=246, Percent_Identity=30.0813008130081, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1789057, Length=261, Percent_Identity=27.9693486590038, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1786701, Length=199, Percent_Identity=31.1557788944724, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1786812, Length=258, Percent_Identity=26.3565891472868, Blast_Score=61, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI25147288, Length=250, Percent_Identity=34.8, Blast_Score=117, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI17562910, Length=257, Percent_Identity=31.9066147859922, Blast_Score=114, Evalue=7e-26,
Organism=Caenorhabditis elegans, GI17561402, Length=250, Percent_Identity=32, Blast_Score=111, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI17562906, Length=261, Percent_Identity=31.0344827586207, Blast_Score=110, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI17559104, Length=258, Percent_Identity=30.6201550387597, Blast_Score=109, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI71994604, Length=249, Percent_Identity=32.1285140562249, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17560676, Length=252, Percent_Identity=32.5396825396825, Blast_Score=108, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI71994600, Length=251, Percent_Identity=31.8725099601594, Blast_Score=107, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI17562908, Length=262, Percent_Identity=31.2977099236641, Blast_Score=105, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17538480, Length=264, Percent_Identity=29.9242424242424, Blast_Score=103, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI17555706, Length=248, Percent_Identity=34.6774193548387, Blast_Score=102, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17563726, Length=261, Percent_Identity=31.0344827586207, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17551412, Length=261, Percent_Identity=31.0344827586207, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17531453, Length=261, Percent_Identity=30.2681992337165, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17562990, Length=257, Percent_Identity=31.9066147859922, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17562904, Length=257, Percent_Identity=29.9610894941634, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI72000259, Length=256, Percent_Identity=30.46875, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17565030, Length=257, Percent_Identity=31.1284046692607, Blast_Score=97, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI17560332, Length=257, Percent_Identity=29.9610894941634, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17560150, Length=261, Percent_Identity=30.2681992337165, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17538486, Length=263, Percent_Identity=27.7566539923954, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17544670, Length=264, Percent_Identity=25.7575757575758, Blast_Score=91, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI193204405, Length=262, Percent_Identity=29.0076335877863, Blast_Score=91, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17536025, Length=262, Percent_Identity=30.1526717557252, Blast_Score=84, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17560220, Length=259, Percent_Identity=28.5714285714286, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17536651, Length=253, Percent_Identity=29.6442687747036, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI115534694, Length=243, Percent_Identity=27.9835390946502, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI32563809, Length=193, Percent_Identity=30.0518134715026, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17507613, Length=193, Percent_Identity=30.0518134715026, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71982365, Length=191, Percent_Identity=26.1780104712042, Blast_Score=64, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17561272, Length=178, Percent_Identity=29.2134831460674, Blast_Score=64, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6324126, Length=259, Percent_Identity=30.8880308880309, Blast_Score=86, Evalue=8e-18,
Organism=Saccharomyces cerevisiae, GI6323882, Length=251, Percent_Identity=27.8884462151394, Blast_Score=69, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6322067, Length=206, Percent_Identity=28.6407766990291, Blast_Score=66, Evalue=6e-12,
Organism=Drosophila melanogaster, GI23397609, Length=251, Percent_Identity=38.2470119521912, Blast_Score=135, Evalue=3e-32,
Organism=Drosophila melanogaster, GI24639444, Length=256, Percent_Identity=35.9375, Blast_Score=125, Evalue=3e-29,
Organism=Drosophila melanogaster, GI28571526, Length=252, Percent_Identity=36.1111111111111, Blast_Score=124, Evalue=7e-29,
Organism=Drosophila melanogaster, GI21357041, Length=251, Percent_Identity=36.6533864541833, Blast_Score=124, Evalue=8e-29,
Organism=Drosophila melanogaster, GI24644339, Length=250, Percent_Identity=31.6, Blast_Score=112, Evalue=3e-25,
Organism=Drosophila melanogaster, GI21355319, Length=250, Percent_Identity=31.6, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24643142, Length=246, Percent_Identity=33.739837398374, Blast_Score=106, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24644337, Length=228, Percent_Identity=35.9649122807018, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI21355631, Length=207, Percent_Identity=29.951690821256, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI17737361, Length=255, Percent_Identity=27.4509803921569, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI21357673, Length=191, Percent_Identity=27.2251308900524, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 25671; Mature: 25540

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: PS00061 ADH_SHORT ; PS00867 CPSASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGVEPQRTALVTGGSSGIGFAIARRLIDDGYRVAIVARDAQRLAASVAQLGDAAFGHAA
CCCCCCCCEEEEECCCCCHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHCCHHCCCCC
DLSVRRDAEAAVAAIVARWPCIDVLVNNAGLTRRVSADTPLDDAEAAWDAVIEANLKSAF
CCCHHCCHHHHHHHHHHHCCEEEEEECCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHH
VTTLAVLPHLAAHDARIVNVGSIAARAGSLLPGGLAYAAAKAGVEGFTVALARELGPRGV
HHHHHHHHHHHHCCCEEEECCHHHHHCCCCCCCHHHHHHHHCCCCHHHHHHHHHCCCCCE
TVNTVAPGYIADTRFFGDGGVASDIAATIREQTPVGRAGQPADIADAVAWLASPRAAFVT
EEECCCCCEEECCEEECCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCEEEE
GATIAVNGGWRVG
CCEEEECCCEECC
>Mature Secondary Structure 
TGVEPQRTALVTGGSSGIGFAIARRLIDDGYRVAIVARDAQRLAASVAQLGDAAFGHAA
CCCCCCCEEEEECCCCCHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHCCHHCCCCC
DLSVRRDAEAAVAAIVARWPCIDVLVNNAGLTRRVSADTPLDDAEAAWDAVIEANLKSAF
CCCHHCCHHHHHHHHHHHCCEEEEEECCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHH
VTTLAVLPHLAAHDARIVNVGSIAARAGSLLPGGLAYAAAKAGVEGFTVALARELGPRGV
HHHHHHHHHHHHCCCEEEECCHHHHHCCCCCCCHHHHHHHHCCCCHHHHHHHHHCCCCCE
TVNTVAPGYIADTRFFGDGGVASDIAATIREQTPVGRAGQPADIADAVAWLASPRAAFVT
EEECCCCCEEECCEEECCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCEEEE
GATIAVNGGWRVG
CCEEEECCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]