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The map label for this gene is lrp [C]

Identifier: 189353296

GI number: 189353296

Start: 1534289

End: 1534756

Strand: Direct

Name: lrp [C]

Synonym: BMULJ_04536

Alternate gene names: 189353296

Gene position: 1534289-1534756 (Clockwise)

Preceding gene: 189353294

Following gene: 189353302

Centisome position: 62.04

GC content: 61.11

Gene sequence:

>468_bases
ATGCTAGACAACTACGATCTGAAGCTGCTGAGCGAGATCCAGCGCGACGCCGATACGCCGCAAAGCGAACTCGCCGCGCG
CGTGAACCTGTCGCCGGCGGCCGTGAACCGCCGGTTGCGGCGGCTCGCCGACGAAGGCGTGATCGACCGCTATACGGCGA
TCCTCGCGCCCGAAAAGGTCGGCTACCCGTTGACGATCGTCACGATGATCGAAGTCGAAAGCGAACAGATCGACCTGCTC
GATGCGATGAAACGCACGTTCGAAGCGTGTGCGCAGATCCAGCAGTGCTACTACGTCGCGGGCGAATGGGACTTCGTGCT
GATTTTCTCTGTGCGTCACATGGAGGAGTACAACGACCTGACGCGGCAGCTGTTCTTCGCGAACAACAACGTGAAGCGGT
TCAAGACGCTCGTGACGATGAGTCGCGTGAAGGCGGGGCTCGAGATTCCGATCGGCCCCGCGACCTGA

Upstream 100 bases:

>100_bases
CGCGTTGTCGCAAAAATAATATTTCATGGCACGTCGAATTTCGGCGCATTCTTCGCCGCCGTTTTGCAAGAAAATTTCGC
CTCTCCACCCCGCCACCCGA

Downstream 100 bases:

>100_bases
CGCGCCGCCGACTCAGACGTGAGTCGCCGCCCGGTTCGCCGCGCCGGCCGCCCAGGCCGCCTGTCGCGCCAGCACCGCGT
CGGCCGTCTCGCCGACCAGT

Product: AsnC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 155; Mature: 155

Protein sequence:

>155_residues
MLDNYDLKLLSEIQRDADTPQSELAARVNLSPAAVNRRLRRLADEGVIDRYTAILAPEKVGYPLTIVTMIEVESEQIDLL
DAMKRTFEACAQIQQCYYVAGEWDFVLIFSVRHMEEYNDLTRQLFFANNNVKRFKTLVTMSRVKAGLEIPIGPAT

Sequences:

>Translated_155_residues
MLDNYDLKLLSEIQRDADTPQSELAARVNLSPAAVNRRLRRLADEGVIDRYTAILAPEKVGYPLTIVTMIEVESEQIDLL
DAMKRTFEACAQIQQCYYVAGEWDFVLIFSVRHMEEYNDLTRQLFFANNNVKRFKTLVTMSRVKAGLEIPIGPAT
>Mature_155_residues
MLDNYDLKLLSEIQRDADTPQSELAARVNLSPAAVNRRLRRLADEGVIDRYTAILAPEKVGYPLTIVTMIEVESEQIDLL
DAMKRTFEACAQIQQCYYVAGEWDFVLIFSVRHMEEYNDLTRQLFFANNNVKRFKTLVTMSRVKAGLEIPIGPAT

Specific function: Mediates A Global Response To Leucine. Exogenous Leucine Affects The Expression Of A Number Of Different Operons; Lrp Mediates This Effect For At Least Some Of These Operons. For Example It Is Regulator Of The Branched-Chain Amino Acid Transport Genes. [

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787116, Length=143, Percent_Identity=31.4685314685315, Blast_Score=78, Evalue=3e-16,
Organism=Escherichia coli, GI87081742, Length=151, Percent_Identity=27.1523178807947, Blast_Score=71, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR013196
- InterPro:   IPR000485
- InterPro:   IPR019885
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg; PF08279 HTH_11 [H]

EC number: NA

Molecular weight: Translated: 17717; Mature: 17717

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: PS00519 HTH_ASNC_1 ; PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDNYDLKLLSEIQRDADTPQSELAARVNLSPAAVNRRLRRLADEGVIDRYTAILAPEKV
CCCCCHHHHHHHHHHCCCCCHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHCHHHC
GYPLTIVTMIEVESEQIDLLDAMKRTFEACAQIQQCYYVAGEWDFVLIFSVRHMEEYNDL
CCCEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHH
TRQLFFANNNVKRFKTLVTMSRVKAGLEIPIGPAT
HHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MLDNYDLKLLSEIQRDADTPQSELAARVNLSPAAVNRRLRRLADEGVIDRYTAILAPEKV
CCCCCHHHHHHHHHHCCCCCHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHCHHHC
GYPLTIVTMIEVESEQIDLLDAMKRTFEACAQIQQCYYVAGEWDFVLIFSVRHMEEYNDL
CCCEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHH
TRQLFFANNNVKRFKTLVTMSRVKAGLEIPIGPAT
HHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]