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The map label for this gene is mocR [H]

Identifier: 189353302

GI number: 189353302

Start: 1539955

End: 1541376

Strand: Direct

Name: mocR [H]

Synonym: BMULJ_04542

Alternate gene names: 189353302

Gene position: 1539955-1541376 (Clockwise)

Preceding gene: 189353296

Following gene: 189353312

Centisome position: 62.27

GC content: 64.84

Gene sequence:

>1422_bases
ATGAATCGAGATTTTGAAATTCAGCTCGACCGGACGGCGAAGCTGTCCCTGGCAGAACAAATCCACATCAGTATCAGCAG
AGCAATAGAGTCAGGCTTGCTCGCACCCGGCACACGCCTCCCTTCATGGCAAGACCTCGCAGCGCAGCTCGGCGTCGCGC
GCGGCACCGTGCAGTCGGCGTACGAGCGCCTGTCCGACGCGCAAATGATCGAAACCTTCGGCGCCAGAGGGACGCGCGTT
GCACCACGATCGCGCGTCGTGCTGTCGCGGCCGCAGGTGCCGCCGGTCGGCGCGTTCATGAAGGCCTACGACGAGATGAA
CGCGGGGCCTGCGATCTTTCAGCTCGGCATTCCGGCGTTCGAAGGGCTGCCGGAGAAGCTGTTCTCCCGTTCGCGCTCGT
CGAACCTGCTGAAGGCCGGATCCCTGTCGTCGTTGCTCTATCCCGATCCGCGCGGCGAGCTCGAACTGCGCACCGAGATC
GCCGCGAATCTGGCGATCACGCGCAACTTTCACTGCCATCCCGAGCAGGTGTTCGTCACGTCCGGCTACGTGGCCGGCCT
GGGGCTGGCGCTGCGCGTGCTGGGCATCGACGGCAAAAAAGTCTGGATGGAAGAGCCGGGATTCATGGTCACGCGCAAAG
GACTCGAGCTCGCGCGTCTGAAGCTCGTGCCGGTGCCGGTCGATGCAGACGGCATCAACGTCGATTACGCACTCGCGAAA
GCACCCGACGCCGCGCTGGCCGTCGTGACACCCGGTCAGCAGGCGCCGCTCGGATCGACCCTCTCGTTGCGACGGCGTCT
CCAGATGCTCGAATGGGCACGCACGAATCATGCATGGATCATCGAAGACGACTACCTCGGCGAGCTGCAGCTGCAAGGCC
GGCCGGCACCCGCAATGGCGTCCCTCGACGAAGGCAAGCGCGTGATTCATGTCGGCTCCTTCAGCAAGACCATCAGCCCG
GCGCTGCGGCTCGGCTTCGTCGTCGCGCCTATCGAACTCGTCAATGCGTTCTCCGAAGTCACCGCAACGCTCGCCCCTGC
GCCGTCGCCGGTAATCCAGCTCGCAACGGCCGAATTCATGCGGCGTGGCCACTATATCCGGCGCGTGCGTCGGCTCAAGC
GCCTTTATTCCGCACAGCGCGACGCACTCTGCGATCAGTTGAGAATGCGCAACGCGGAATGGATAACGGCCGGCCTATCC
GTCCTGCTCAGGCTTCCCGATGGCGCGCCCGACACGAAAATCGTCAGGGACGCGATGACGGTCGGCATCGCGCCGTCGCC
GCTGTCCGCGTGGTTCGCGACGCCTTCCTGGACGAGGCCCGGCCTTCTGCTCAGCGTCGCGACCGCACCCGAACAGCACG
TGGCGACGTCGTGCCGCCGGCTGTTCGACATCATCGAACGCCACTGCGGAAAGGCGCGGTAG

Upstream 100 bases:

>100_bases
TCCGCCCTTACATCCGCGGCCGCGATCGTGCGAAGATTCTGTGCGATCGACGACACGGATAGTAGAACCAAGATTTCCCA
TTTTTGTGTGTACCAAGCGG

Downstream 100 bases:

>100_bases
CGACCGGTCGCCTGCGATCGCGGCAGGCGGTCTCCGCCGTCCGCCGCGCTTCACCCCCATCGGTTCTCGCGCGCGATGCG
TCTCGGCCGTAACCGGTCAC

Product: transcriptional MocR family regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 473; Mature: 473

Protein sequence:

>473_residues
MNRDFEIQLDRTAKLSLAEQIHISISRAIESGLLAPGTRLPSWQDLAAQLGVARGTVQSAYERLSDAQMIETFGARGTRV
APRSRVVLSRPQVPPVGAFMKAYDEMNAGPAIFQLGIPAFEGLPEKLFSRSRSSNLLKAGSLSSLLYPDPRGELELRTEI
AANLAITRNFHCHPEQVFVTSGYVAGLGLALRVLGIDGKKVWMEEPGFMVTRKGLELARLKLVPVPVDADGINVDYALAK
APDAALAVVTPGQQAPLGSTLSLRRRLQMLEWARTNHAWIIEDDYLGELQLQGRPAPAMASLDEGKRVIHVGSFSKTISP
ALRLGFVVAPIELVNAFSEVTATLAPAPSPVIQLATAEFMRRGHYIRRVRRLKRLYSAQRDALCDQLRMRNAEWITAGLS
VLLRLPDGAPDTKIVRDAMTVGIAPSPLSAWFATPSWTRPGLLLSVATAPEQHVATSCRRLFDIIERHCGKAR

Sequences:

>Translated_473_residues
MNRDFEIQLDRTAKLSLAEQIHISISRAIESGLLAPGTRLPSWQDLAAQLGVARGTVQSAYERLSDAQMIETFGARGTRV
APRSRVVLSRPQVPPVGAFMKAYDEMNAGPAIFQLGIPAFEGLPEKLFSRSRSSNLLKAGSLSSLLYPDPRGELELRTEI
AANLAITRNFHCHPEQVFVTSGYVAGLGLALRVLGIDGKKVWMEEPGFMVTRKGLELARLKLVPVPVDADGINVDYALAK
APDAALAVVTPGQQAPLGSTLSLRRRLQMLEWARTNHAWIIEDDYLGELQLQGRPAPAMASLDEGKRVIHVGSFSKTISP
ALRLGFVVAPIELVNAFSEVTATLAPAPSPVIQLATAEFMRRGHYIRRVRRLKRLYSAQRDALCDQLRMRNAEWITAGLS
VLLRLPDGAPDTKIVRDAMTVGIAPSPLSAWFATPSWTRPGLLLSVATAPEQHVATSCRRLFDIIERHCGKAR
>Mature_473_residues
MNRDFEIQLDRTAKLSLAEQIHISISRAIESGLLAPGTRLPSWQDLAAQLGVARGTVQSAYERLSDAQMIETFGARGTRV
APRSRVVLSRPQVPPVGAFMKAYDEMNAGPAIFQLGIPAFEGLPEKLFSRSRSSNLLKAGSLSSLLYPDPRGELELRTEI
AANLAITRNFHCHPEQVFVTSGYVAGLGLALRVLGIDGKKVWMEEPGFMVTRKGLELARLKLVPVPVDADGINVDYALAK
APDAALAVVTPGQQAPLGSTLSLRRRLQMLEWARTNHAWIIEDDYLGELQLQGRPAPAMASLDEGKRVIHVGSFSKTISP
ALRLGFVVAPIELVNAFSEVTATLAPAPSPVIQLATAEFMRRGHYIRRVRRLKRLYSAQRDALCDQLRMRNAEWITAGLS
VLLRLPDGAPDTKIVRDAMTVGIAPSPLSAWFATPSWTRPGLLLSVATAPEQHVATSCRRLFDIIERHCGKAR

Specific function: Could play a regulatory role in the transcription of the moc genes for rhizopine catabolism. Could also have an aminotransferase activity [H]

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=310, Percent_Identity=28.7096774193548, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI33469970, Length=310, Percent_Identity=28.7096774193548, Blast_Score=89, Evalue=7e-18,
Organism=Escherichia coli, GI1787710, Length=447, Percent_Identity=28.8590604026846, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1790797, Length=370, Percent_Identity=28.6486486486486, Blast_Score=110, Evalue=2e-25,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 51767; Mature: 51767

Theoretical pI: Translated: 10.16; Mature: 10.16

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRDFEIQLDRTAKLSLAEQIHISISRAIESGLLAPGTRLPSWQDLAAQLGVARGTVQSA
CCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
YERLSDAQMIETFGARGTRVAPRSRVVLSRPQVPPVGAFMKAYDEMNAGPAIFQLGIPAF
HHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHCCCCCEEEEECCCHH
EGLPEKLFSRSRSSNLLKAGSLSSLLYPDPRGELELRTEIAANLAITRNFHCHPEQVFVT
CCCHHHHHHCCCCCCCEECCCCCCCCCCCCCCCEEEHHHHHHEEEEECCCCCCCCEEEEE
SGYVAGLGLALRVLGIDGKKVWMEEPGFMVTRKGLELARLKLVPVPVDADGINVDYALAK
CCHHHHHHHHHEEEECCCCEEEECCCCEEEECCCCEEEEEEEEEECCCCCCCCEEEEEEC
APDAALAVVTPGQQAPLGSTLSLRRRLQMLEWARTNHAWIIEDDYLGELQLQGRPAPAMA
CCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEECCCCCCCHH
SLDEGKRVIHVGSFSKTISPALRLGFVVAPIELVNAFSEVTATLAPAPSPVIQLATAEFM
CCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
RRGHYIRRVRRLKRLYSAQRDALCDQLRMRNAEWITAGLSVLLRLPDGAPDTKIVRDAMT
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHEEECCCCCCCHHHHHHHHH
VGIAPSPLSAWFATPSWTRPGLLLSVATAPEQHVATSCRRLFDIIERHCGKAR
HCCCCCCCHHHCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MNRDFEIQLDRTAKLSLAEQIHISISRAIESGLLAPGTRLPSWQDLAAQLGVARGTVQSA
CCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
YERLSDAQMIETFGARGTRVAPRSRVVLSRPQVPPVGAFMKAYDEMNAGPAIFQLGIPAF
HHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHCCCCCEEEEECCCHH
EGLPEKLFSRSRSSNLLKAGSLSSLLYPDPRGELELRTEIAANLAITRNFHCHPEQVFVT
CCCHHHHHHCCCCCCCEECCCCCCCCCCCCCCCEEEHHHHHHEEEEECCCCCCCCEEEEE
SGYVAGLGLALRVLGIDGKKVWMEEPGFMVTRKGLELARLKLVPVPVDADGINVDYALAK
CCHHHHHHHHHEEEECCCCEEEECCCCEEEECCCCEEEEEEEEEECCCCCCCCEEEEEEC
APDAALAVVTPGQQAPLGSTLSLRRRLQMLEWARTNHAWIIEDDYLGELQLQGRPAPAMA
CCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEECCCCCCCHH
SLDEGKRVIHVGSFSKTISPALRLGFVVAPIELVNAFSEVTATLAPAPSPVIQLATAEFM
CCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
RRGHYIRRVRRLKRLYSAQRDALCDQLRMRNAEWITAGLSVLLRLPDGAPDTKIVRDAMT
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHEEECCCCCCCHHHHHHHHH
VGIAPSPLSAWFATPSWTRPGLLLSVATAPEQHVATSCRRLFDIIERHCGKAR
HCCCCCCCHHHCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7845353 [H]