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The map label for this gene is yafC [H]

Identifier: 189353149

GI number: 189353149

Start: 1347766

End: 1348737

Strand: Reverse

Name: yafC [H]

Synonym: BMULJ_04385

Alternate gene names: 189353149

Gene position: 1348737-1347766 (Counterclockwise)

Preceding gene: 189353153

Following gene: 189353146

Centisome position: 54.53

GC content: 66.98

Gene sequence:

>972_bases
ATGGACATGCTCGAAAACATGCGCCTGTTCGTGCGCGTTGTCGAAGCCGGCAGTTTCACCGCGGTTGCGAAAGAGATCGA
TGCGACCACGGCGCAGGTGTCGCGCGCCGTGTCGAATCTCGAGGCGCACGTGCAGACGCGTCTTCTGCATCGCACGACGC
GCCACCTCGGTCTGACCGAAAGCGGCGAGCGCTATTTCGAGCGCGCGAAATCGATCCTTGCGGAGATCGACTACGCGAAC
GCCGAGGCGCGCAATGCGCTGCTGCGGCCGAGCGGGAAGATGCGCATCCATGCGATGACGGGGCTCGGGCAGAGTCATGT
CGTGTCGTCGATCGTCCGCTATCAGGAGGACAACCCCGAGGTGTCGGTCGAGCTGACGCTTGCGCAGCGCATGCCGAACC
TCGTCGAGGAAGGGTACGACGTGTCGATCGTCACGGCGTCGCAGTTGCCCGATTCGGGCTACGTCGCGCAGACCTGCGGC
ACGAGCTGCAGCGTGCTCGTCGCGTCGCGCGACTATCTCGCGCGGCACGGTACGCCGCAGACGCCGGACGATCTGCCGAA
CCACGTGTGCCTGCGCCTCGACACACCGGCGTCGCCCGCGAGCGAGTGGCGGCTCGAACGCGCCGACGGCGAGGAAACCG
TGTACGAACTGCAGCCCGCGCCGTTCCAGGTCAACGTGCCGGACGCGCTCTGCGTCGCAGTGCGCGCCGGGCGCGGGATC
GCCTGCGTCGCGCTCTATACGGTGCTCGACGACATCCGCGAAGGGCGGCTGATCCGCGTGCTGCCCGAGTACCGGTTGCA
GACCGTCAGCGTCTATGCGGTCTATGCGACGCGCCGCTATCTCGACGCGAAGATCCGCACGTTCCTCGACCATCTGCGCA
CGACGCTGACGCCGGCGCTGGAGAACGATCTGCGCGAGCTCGACCGGCTCACGATCGAGCAGGCGCAAAGCGGCGGTCTG
AAGCGCGCGTGA

Upstream 100 bases:

>100_bases
CGGTGAGCGATGTCGCGCGGTTCGCGGCCGTGCTGCATCGCCCGGCTGACGCGCGCGCGGCCGACGCCTTCTCCCCACAG
ACTCTCCCGAAGCCAATTCA

Downstream 100 bases:

>100_bases
TGCGGCGCGCGGGAGTATCGCCCGAACGCGCGATCCTGCACCGCGGCGATCACCGGTCCGCTGCGACGCGAATGCGCTCG
AAGCGGCCCGCGAGCCACGC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 323; Mature: 323

Protein sequence:

>323_residues
MDMLENMRLFVRVVEAGSFTAVAKEIDATTAQVSRAVSNLEAHVQTRLLHRTTRHLGLTESGERYFERAKSILAEIDYAN
AEARNALLRPSGKMRIHAMTGLGQSHVVSSIVRYQEDNPEVSVELTLAQRMPNLVEEGYDVSIVTASQLPDSGYVAQTCG
TSCSVLVASRDYLARHGTPQTPDDLPNHVCLRLDTPASPASEWRLERADGEETVYELQPAPFQVNVPDALCVAVRAGRGI
ACVALYTVLDDIREGRLIRVLPEYRLQTVSVYAVYATRRYLDAKIRTFLDHLRTTLTPALENDLRELDRLTIEQAQSGGL
KRA

Sequences:

>Translated_323_residues
MDMLENMRLFVRVVEAGSFTAVAKEIDATTAQVSRAVSNLEAHVQTRLLHRTTRHLGLTESGERYFERAKSILAEIDYAN
AEARNALLRPSGKMRIHAMTGLGQSHVVSSIVRYQEDNPEVSVELTLAQRMPNLVEEGYDVSIVTASQLPDSGYVAQTCG
TSCSVLVASRDYLARHGTPQTPDDLPNHVCLRLDTPASPASEWRLERADGEETVYELQPAPFQVNVPDALCVAVRAGRGI
ACVALYTVLDDIREGRLIRVLPEYRLQTVSVYAVYATRRYLDAKIRTFLDHLRTTLTPALENDLRELDRLTIEQAQSGGL
KRA
>Mature_323_residues
MDMLENMRLFVRVVEAGSFTAVAKEIDATTAQVSRAVSNLEAHVQTRLLHRTTRHLGLTESGERYFERAKSILAEIDYAN
AEARNALLRPSGKMRIHAMTGLGQSHVVSSIVRYQEDNPEVSVELTLAQRMPNLVEEGYDVSIVTASQLPDSGYVAQTCG
TSCSVLVASRDYLARHGTPQTPDDLPNHVCLRLDTPASPASEWRLERADGEETVYELQPAPFQVNVPDALCVAVRAGRGI
ACVALYTVLDDIREGRLIRVLPEYRLQTVSVYAVYATRRYLDAKIRTFLDHLRTTLTPALENDLRELDRLTIEQAQSGGL
KRA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=305, Percent_Identity=36.3934426229508, Blast_Score=172, Evalue=4e-44,
Organism=Escherichia coli, GI1789639, Length=293, Percent_Identity=31.740614334471, Blast_Score=147, Evalue=7e-37,
Organism=Escherichia coli, GI145693193, Length=301, Percent_Identity=31.8936877076412, Blast_Score=146, Evalue=1e-36,
Organism=Escherichia coli, GI87081978, Length=293, Percent_Identity=30.3754266211604, Blast_Score=141, Evalue=6e-35,
Organism=Escherichia coli, GI1789440, Length=288, Percent_Identity=29.5138888888889, Blast_Score=134, Evalue=6e-33,
Organism=Escherichia coli, GI1787128, Length=295, Percent_Identity=27.1186440677966, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1787589, Length=292, Percent_Identity=27.7397260273973, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1788481, Length=310, Percent_Identity=22.5806451612903, Blast_Score=69, Evalue=3e-13,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35907; Mature: 35907

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDMLENMRLFVRVVEAGSFTAVAKEIDATTAQVSRAVSNLEAHVQTRLLHRTTRHLGLTE
CCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
SGERYFERAKSILAEIDYANAEARNALLRPSGKMRIHAMTGLGQSHVVSSIVRYQEDNPE
CHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCCC
VSVELTLAQRMPNLVEEGYDVSIVTASQLPDSGYVAQTCGTSCSVLVASRDYLARHGTPQ
EEEEEEHHHHCHHHHHCCCCEEEEECCCCCCCCCCHHHCCCCCEEEEECHHHHHHCCCCC
TPDDLPNHVCLRLDTPASPASEWRLERADGEETVYELQPAPFQVNVPDALCVAVRAGRGI
CCCCCCCCEEEEECCCCCCHHHCEEECCCCCCCEEEECCCCEEEECCHHHHHHHHCCCCC
ACVALYTVLDDIREGRLIRVLPEYRLQTVSVYAVYATRRYLDAKIRTFLDHLRTTLTPAL
HHHHHHHHHHHHHCCCEEEECCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCHHH
ENDLRELDRLTIEQAQSGGLKRA
HHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MDMLENMRLFVRVVEAGSFTAVAKEIDATTAQVSRAVSNLEAHVQTRLLHRTTRHLGLTE
CCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
SGERYFERAKSILAEIDYANAEARNALLRPSGKMRIHAMTGLGQSHVVSSIVRYQEDNPE
CHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCCC
VSVELTLAQRMPNLVEEGYDVSIVTASQLPDSGYVAQTCGTSCSVLVASRDYLARHGTPQ
EEEEEEHHHHCHHHHHCCCCEEEEECCCCCCCCCCHHHCCCCCEEEEECHHHHHHCCCCC
TPDDLPNHVCLRLDTPASPASEWRLERADGEETVYELQPAPFQVNVPDALCVAVRAGRGI
CCCCCCCCEEEEECCCCCCHHHCEEECCCCCCCEEEECCCCEEEECCHHHHHHHHCCCCC
ACVALYTVLDDIREGRLIRVLPEYRLQTVSVYAVYATRRYLDAKIRTFLDHLRTTLTPAL
HHHHHHHHHHHHHCCCEEEECCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCHHH
ENDLRELDRLTIEQAQSGGLKRA
HHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]