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The map label for this gene is paaG [C]

Identifier: 189353142

GI number: 189353142

Start: 1338803

End: 1339603

Strand: Reverse

Name: paaG [C]

Synonym: BMULJ_04378

Alternate gene names: 189353142

Gene position: 1339603-1338803 (Counterclockwise)

Preceding gene: 189353143

Following gene: 189353141

Centisome position: 54.17

GC content: 70.66

Gene sequence:

>801_bases
ATGGATGGATTGAAGACTCTGGCCGTGACGGTCGATGCGCGCGGTATCGCGACCGTCGCATTGCAGCGCGGCGACGTGCT
GAACGCATTCGACGAGACGATGATCGCCGAGCTGACCGACGCGTTTACCGCGCTCGGCGCGCGCGACGACGTGCGCGCGA
TCATGCTGCGCTCGGACGGCCGCGCGTTCTGCGCCGGCGCCGACCTGCAATGGATGCAGCGTGCGAGCGCGAACGACGCG
GCCGCGAACCTGCGCGACGCGGAGCGGTTCGCCGCGATGATGCGCGCGATCCGGCAGTGTCCGAAGCCGACCGTCGCGCG
TGTGCAGGGCCACGCGTTCGGCGGCGGCGTCGGCCTCTGCGCGGCCTGCGACATCGTGATCGCGAGCGAGCACGCGCGGT
TCGCGGTCAGCGAGGCGCGCTTCGGGATTCTGCCGGCCGTGATCGGGCCGTATCTCGTCGAGGCAGTGGGCCAGCGTCAG
GCGCGCCGGCTCGCGCTGACGGCGACGCAGCTGAGCGCGCACGACGCGGTCGCGATCGGGCTCATCCATCAGGCCGTCCC
GCTCGATGCACTCGACGACGCGCTCGACAAGACGCTCGCCGAACTCGGCCGCAACGGCCCGAACGCGCTGATGGAGATCA
AGCGCTTCTTCGATGCGATCGGCGAGTATCCGCCGTCGGACGCGCGCGCGGCGTTCACGGCGCAGACGATCTCGCGCGTG
CGCGCGACCGACGAAGCGAAGGAGGGCTTCGCCGCGTTCTTCGCGAAGCGTGCGCCTGCGTGGGAGCCGGCTGCGGAATA
A

Upstream 100 bases:

>100_bases
GCGCGACCGGCAAGGCGCGCCGCGTGGTCGACCGGCGGATCGCCGCGTAATCGCGGCGCCGTGGTCGGCGCTGCTGTCTT
TTAGCGAGGAAACCTGTTCG

Downstream 100 bases:

>100_bases
ACGCGGGGCTGCGCATCGTGTTCTCGCCTCGCTCGCGGGATGCGCGCGCGAGCGGCGCGTTGCGCAACGCGTGCGCGATT
TGCGCGCGGCGCCAGGCGCT

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: 3-hydroxypropionyl-CoA dehydratase [H]

Number of amino acids: Translated: 266; Mature: 266

Protein sequence:

>266_residues
MDGLKTLAVTVDARGIATVALQRGDVLNAFDETMIAELTDAFTALGARDDVRAIMLRSDGRAFCAGADLQWMQRASANDA
AANLRDAERFAAMMRAIRQCPKPTVARVQGHAFGGGVGLCAACDIVIASEHARFAVSEARFGILPAVIGPYLVEAVGQRQ
ARRLALTATQLSAHDAVAIGLIHQAVPLDALDDALDKTLAELGRNGPNALMEIKRFFDAIGEYPPSDARAAFTAQTISRV
RATDEAKEGFAAFFAKRAPAWEPAAE

Sequences:

>Translated_266_residues
MDGLKTLAVTVDARGIATVALQRGDVLNAFDETMIAELTDAFTALGARDDVRAIMLRSDGRAFCAGADLQWMQRASANDA
AANLRDAERFAAMMRAIRQCPKPTVARVQGHAFGGGVGLCAACDIVIASEHARFAVSEARFGILPAVIGPYLVEAVGQRQ
ARRLALTATQLSAHDAVAIGLIHQAVPLDALDDALDKTLAELGRNGPNALMEIKRFFDAIGEYPPSDARAAFTAQTISRV
RATDEAKEGFAAFFAKRAPAWEPAAE
>Mature_266_residues
MDGLKTLAVTVDARGIATVALQRGDVLNAFDETMIAELTDAFTALGARDDVRAIMLRSDGRAFCAGADLQWMQRASANDA
AANLRDAERFAAMMRAIRQCPKPTVARVQGHAFGGGVGLCAACDIVIASEHARFAVSEARFGILPAVIGPYLVEAVGQRQ
ARRLALTATQLSAHDAVAIGLIHQAVPLDALDDALDKTLAELGRNGPNALMEIKRFFDAIGEYPPSDARAAFTAQTISRV
RATDEAKEGFAAFFAKRAPAWEPAAE

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl- CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crot

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=243, Percent_Identity=31.6872427983539, Blast_Score=110, Evalue=1e-24,
Organism=Homo sapiens, GI31542718, Length=252, Percent_Identity=26.984126984127, Blast_Score=92, Evalue=6e-19,
Organism=Homo sapiens, GI70995211, Length=279, Percent_Identity=28.3154121863799, Blast_Score=91, Evalue=8e-19,
Organism=Homo sapiens, GI4502327, Length=270, Percent_Identity=30.3703703703704, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI37594471, Length=176, Percent_Identity=28.9772727272727, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI37594469, Length=176, Percent_Identity=28.9772727272727, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI4757966, Length=206, Percent_Identity=26.2135922330097, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI51538581, Length=206, Percent_Identity=26.2135922330097, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI25453481, Length=206, Percent_Identity=26.2135922330097, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI51538573, Length=206, Percent_Identity=26.2135922330097, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI4757968, Length=176, Percent_Identity=28.4090909090909, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI49355787, Length=176, Percent_Identity=28.4090909090909, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI116235487, Length=159, Percent_Identity=30.188679245283, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1788597, Length=265, Percent_Identity=29.4339622641509, Blast_Score=103, Evalue=8e-24,
Organism=Escherichia coli, GI1787659, Length=249, Percent_Identity=28.9156626506024, Blast_Score=98, Evalue=5e-22,
Organism=Escherichia coli, GI87082183, Length=256, Percent_Identity=24.609375, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI1787660, Length=250, Percent_Identity=30.8, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI221142681, Length=250, Percent_Identity=28, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1790281, Length=193, Percent_Identity=25.3886010362694, Blast_Score=67, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17554946, Length=252, Percent_Identity=29.7619047619048, Blast_Score=100, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI25145438, Length=258, Percent_Identity=28.2945736434109, Blast_Score=97, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI17540306, Length=236, Percent_Identity=26.6949152542373, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17536985, Length=259, Percent_Identity=28.1853281853282, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17540714, Length=188, Percent_Identity=27.1276595744681, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17534483, Length=197, Percent_Identity=24.8730964467005, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI25144157, Length=254, Percent_Identity=27.9527559055118, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI25144160, Length=254, Percent_Identity=27.9527559055118, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17560910, Length=168, Percent_Identity=26.7857142857143, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17549921, Length=203, Percent_Identity=26.6009852216749, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24653139, Length=268, Percent_Identity=27.9850746268657, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI19922422, Length=261, Percent_Identity=21.8390804597701, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI20129971, Length=247, Percent_Identity=27.5303643724696, Blast_Score=91, Evalue=7e-19,
Organism=Drosophila melanogaster, GI24653477, Length=247, Percent_Identity=27.5303643724696, Blast_Score=91, Evalue=7e-19,
Organism=Drosophila melanogaster, GI19920382, Length=197, Percent_Identity=32.994923857868, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21357171, Length=195, Percent_Identity=28.2051282051282, Blast_Score=64, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.116 [H]

Molecular weight: Translated: 28281; Mature: 28281

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDGLKTLAVTVDARGIATVALQRGDVLNAFDETMIAELTDAFTALGARDDVRAIMLRSDG
CCCCEEEEEEECCCCHHHHHECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCC
RAFCAGADLQWMQRASANDAAANLRDAERFAAMMRAIRQCPKPTVARVQGHAFGGGVGLC
CEEEECCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCHHHH
AACDIVIASEHARFAVSEARFGILPAVIGPYLVEAVGQRQARRLALTATQLSAHDAVAIG
HHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIHQAVPLDALDDALDKTLAELGRNGPNALMEIKRFFDAIGEYPPSDARAAFTAQTISRV
HHHHHCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
RATDEAKEGFAAFFAKRAPAWEPAAE
HHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MDGLKTLAVTVDARGIATVALQRGDVLNAFDETMIAELTDAFTALGARDDVRAIMLRSDG
CCCCEEEEEEECCCCHHHHHECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCC
RAFCAGADLQWMQRASANDAAANLRDAERFAAMMRAIRQCPKPTVARVQGHAFGGGVGLC
CEEEECCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCHHHH
AACDIVIASEHARFAVSEARFGILPAVIGPYLVEAVGQRQARRLALTATQLSAHDAVAIG
HHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIHQAVPLDALDDALDKTLAELGRNGPNALMEIKRFFDAIGEYPPSDARAAFTAQTISRV
HHHHHCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
RATDEAKEGFAAFFAKRAPAWEPAAE
HHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA