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The map label for this gene is paaK [H]

Identifier: 189353143

GI number: 189353143

Start: 1339654

End: 1340976

Strand: Reverse

Name: paaK [H]

Synonym: BMULJ_04379

Alternate gene names: 189353143

Gene position: 1340976-1339654 (Counterclockwise)

Preceding gene: 189353144

Following gene: 189353142

Centisome position: 54.22

GC content: 68.63

Gene sequence:

>1323_bases
ATGACTTACCCGACGCACCCCGCCGCCGCGCTCGAGCCGATCGAGACCGCCAGTCGCGACGAACTGCAGGCGCTGCAGCT
CGAGCGCCTCAAATGGTCGCTTCGTCATGCGTATGACAACGTCGCGCACTATCGCCGCACGTTCGACGCGGCGGGCGTGC
ATCCGGACGATCTGAAAACGCTTGCCGATCTCGCGAAGTTTCCGTTCTCGACGAAGCACGACCTGCGCGACAACTATCCG
TTCGGGCTGTTCGCGGTGCCGCGCGAGCAGGTCGTGCGCGTGCACGCGTCGAGCGGCACGACCGGCAAGCCGACCGTGGT
CGGCTACACGGCGCGCGACATCGACACGTGGGCGAACGTCACTGCGCGGTCGATCCGCGCGGCGGGCGGCCGGCCCGGCG
ACACGCTGCACAACGCGTTCGGCTACGGGCTCTTCACCGGCGGGCTCGGGATTCACTACGGCGCGGAGCGGCTCGGCTGC
ATGGTCGTGCCGATGTCGGGCGGCCAGACCGAGAAGCAGGTGCAGCTGATCCGCGACTTCGAGCCGAAGATCATCCTCGT
CACGCCGTCGTACATGCTGAACCTGATCGACGAGATGGTGCGGCAGGGAATGGACCCGGCGCAGTCGTCGCTGAAGATCG
GCATCTTCGGCGCCGAGCCGTGGACGCAGGCGCTGCGCGAAGAAGTGGAGACGCGCGCGGGCATCGATGCGCTCGACATC
TACGGGCTGTCCGAAGTGATGGGCCCGGGCGTCGCGTGCGAATGCGCGGAGACGAAGGACGGCCCGGTGATCTGGGAAGA
CCACTTCTATCCGGAGATCATCGATCCGGTGACGGGCGAGGTGCTGCCGGACGGCAGCGAGGGCGAACTCGTGTTCACGT
CGCTGACGAAGGAGGCGATGCCGGTGATCCGCTACCGCACGCGCGACCTCACCGCGTTGCTGCCGCCGACCGCGCGCGCG
ATGCGTCGTCTCGCGAAGATCACCGGCCGCTCCGACGACATGCTGATCGTGCGCGGCGTGAACGTGTTCCCGAGCCAGAT
CGAGGAGCTCGTCGTCGCGCAGCCGAAGCTGTCCGGCCAATTCCAGATCACGCTGTCGCGCGACGGGCACATGGACCGGC
TCGACCTCGCGGTCGAGCTGCGCTCCGAAGCGACCGCGAGCGTGACCGACGGCGAGCGCGCCGAGATCGCACGCGCGCTG
CAGCATCGGATCAAGACGATGATCGGCGTGTCGGCCGGCGTGACGGTGCTGGCCGCGGGCGGCATTCCGGCGAGCGCGAC
CGGCAAGGCGCGCCGCGTGGTCGACCGGCGGATCGCCGCGTAA

Upstream 100 bases:

>100_bases
TCGCCGCGCATCGCCGCGCGGCACGCGGCCGGCCGGTCGTTGCGCGCGTAGCCGCGATCCCGATCACGACAACGACATAT
TCCCTTGGAGGAGCACCCCG

Downstream 100 bases:

>100_bases
TCGCGGCGCCGTGGTCGGCGCTGCTGTCTTTTAGCGAGGAAACCTGTTCGATGGATGGATTGAAGACTCTGGCCGTGACG
GTCGATGCGCGCGGTATCGC

Product: phenylacetate-CoA ligase

Products: NA

Alternate protein names: Phenylacetyl-CoA ligase; PA-CoA ligase [H]

Number of amino acids: Translated: 440; Mature: 439

Protein sequence:

>440_residues
MTYPTHPAAALEPIETASRDELQALQLERLKWSLRHAYDNVAHYRRTFDAAGVHPDDLKTLADLAKFPFSTKHDLRDNYP
FGLFAVPREQVVRVHASSGTTGKPTVVGYTARDIDTWANVTARSIRAAGGRPGDTLHNAFGYGLFTGGLGIHYGAERLGC
MVVPMSGGQTEKQVQLIRDFEPKIILVTPSYMLNLIDEMVRQGMDPAQSSLKIGIFGAEPWTQALREEVETRAGIDALDI
YGLSEVMGPGVACECAETKDGPVIWEDHFYPEIIDPVTGEVLPDGSEGELVFTSLTKEAMPVIRYRTRDLTALLPPTARA
MRRLAKITGRSDDMLIVRGVNVFPSQIEELVVAQPKLSGQFQITLSRDGHMDRLDLAVELRSEATASVTDGERAEIARAL
QHRIKTMIGVSAGVTVLAAGGIPASATGKARRVVDRRIAA

Sequences:

>Translated_440_residues
MTYPTHPAAALEPIETASRDELQALQLERLKWSLRHAYDNVAHYRRTFDAAGVHPDDLKTLADLAKFPFSTKHDLRDNYP
FGLFAVPREQVVRVHASSGTTGKPTVVGYTARDIDTWANVTARSIRAAGGRPGDTLHNAFGYGLFTGGLGIHYGAERLGC
MVVPMSGGQTEKQVQLIRDFEPKIILVTPSYMLNLIDEMVRQGMDPAQSSLKIGIFGAEPWTQALREEVETRAGIDALDI
YGLSEVMGPGVACECAETKDGPVIWEDHFYPEIIDPVTGEVLPDGSEGELVFTSLTKEAMPVIRYRTRDLTALLPPTARA
MRRLAKITGRSDDMLIVRGVNVFPSQIEELVVAQPKLSGQFQITLSRDGHMDRLDLAVELRSEATASVTDGERAEIARAL
QHRIKTMIGVSAGVTVLAAGGIPASATGKARRVVDRRIAA
>Mature_439_residues
TYPTHPAAALEPIETASRDELQALQLERLKWSLRHAYDNVAHYRRTFDAAGVHPDDLKTLADLAKFPFSTKHDLRDNYPF
GLFAVPREQVVRVHASSGTTGKPTVVGYTARDIDTWANVTARSIRAAGGRPGDTLHNAFGYGLFTGGLGIHYGAERLGCM
VVPMSGGQTEKQVQLIRDFEPKIILVTPSYMLNLIDEMVRQGMDPAQSSLKIGIFGAEPWTQALREEVETRAGIDALDIY
GLSEVMGPGVACECAETKDGPVIWEDHFYPEIIDPVTGEVLPDGSEGELVFTSLTKEAMPVIRYRTRDLTALLPPTARAM
RRLAKITGRSDDMLIVRGVNVFPSQIEELVVAQPKLSGQFQITLSRDGHMDRLDLAVELRSEATASVTDGERAEIARALQ
HRIKTMIGVSAGVTVLAAGGIPASATGKARRVVDRRIAA

Specific function: Catalyzes the activation of phenylacetic acid to phenylacetyl-CoA [H]

COG id: COG1541

COG function: function code H; Coenzyme F390 synthetase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787664, Length=428, Percent_Identity=67.2897196261682, Blast_Score=604, Evalue=1e-174,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000873
- InterPro:   IPR011880 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: =6.2.1.30 [H]

Molecular weight: Translated: 48054; Mature: 47923

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYPTHPAAALEPIETASRDELQALQLERLKWSLRHAYDNVAHYRRTFDAAGVHPDDLKT
CCCCCCCCHHHCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
LADLAKFPFSTKHDLRDNYPFGLFAVPREQVVRVHASSGTTGKPTVVGYTARDIDTWANV
HHHHHHCCCCCCCCCCCCCCEEEEECCHHHEEEEECCCCCCCCCEEEEEEHHHHHHHHHH
TARSIRAAGGRPGDTLHNAFGYGLFTGGLGIHYGAERLGCMVVPMSGGQTEKQVQLIRDF
HHHHHHHCCCCCCHHHHHHHCCHHEECCCCHHCCHHHHCEEEEECCCCCCHHHHHHHHCC
EPKIILVTPSYMLNLIDEMVRQGMDPAQSSLKIGIFGAEPWTQALREEVETRAGIDALDI
CCCEEEECHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHCCCCHHHH
YGLSEVMGPGVACECAETKDGPVIWEDHFYPEIIDPVTGEVLPDGSEGELVFTSLTKEAM
CCHHHHHCCCCEEEECCCCCCCEEECCCCCHHHHCCCCCCCCCCCCCCCEEEEEHHHHHH
PVIRYRTRDLTALLPPTARAMRRLAKITGRSDDMLIVRGVNVFPSQIEELVVAQPKLSGQ
HHHHHCCCCCEEECCHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCE
FQITLSRDGHMDRLDLAVELRSEATASVTDGERAEIARALQHRIKTMIGVSAGVTVLAAG
EEEEECCCCCCCHHHHHEEHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEC
GIPASATGKARRVVDRRIAA
CCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
TYPTHPAAALEPIETASRDELQALQLERLKWSLRHAYDNVAHYRRTFDAAGVHPDDLKT
CCCCCCCHHHCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
LADLAKFPFSTKHDLRDNYPFGLFAVPREQVVRVHASSGTTGKPTVVGYTARDIDTWANV
HHHHHHCCCCCCCCCCCCCCEEEEECCHHHEEEEECCCCCCCCCEEEEEEHHHHHHHHHH
TARSIRAAGGRPGDTLHNAFGYGLFTGGLGIHYGAERLGCMVVPMSGGQTEKQVQLIRDF
HHHHHHHCCCCCCHHHHHHHCCHHEECCCCHHCCHHHHCEEEEECCCCCCHHHHHHHHCC
EPKIILVTPSYMLNLIDEMVRQGMDPAQSSLKIGIFGAEPWTQALREEVETRAGIDALDI
CCCEEEECHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHCCCCHHHH
YGLSEVMGPGVACECAETKDGPVIWEDHFYPEIIDPVTGEVLPDGSEGELVFTSLTKEAM
CCHHHHHCCCCEEEECCCCCCCEEECCCCCHHHHCCCCCCCCCCCCCCCEEEEEHHHHHH
PVIRYRTRDLTALLPPTARAMRRLAKITGRSDDMLIVRGVNVFPSQIEELVVAQPKLSGQ
HHHHHCCCCCEEECCHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCE
FQITLSRDGHMDRLDLAVELRSEATASVTDGERAEIARALQHRIKTMIGVSAGVTVLAAG
EEEEECCCCCCCHHHHHEEHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEC
GIPASATGKARRVVDRRIAA
CCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9748275; 9278503; 10766858 [H]