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The map label for this gene is zraS [C]

Identifier: 189353132

GI number: 189353132

Start: 1326686

End: 1328452

Strand: Reverse

Name: zraS [C]

Synonym: BMULJ_04368

Alternate gene names: 189353132

Gene position: 1328452-1326686 (Counterclockwise)

Preceding gene: 189353133

Following gene: 189353131

Centisome position: 53.71

GC content: 69.04

Gene sequence:

>1767_bases
ATGAGCGAAATTTCTGTCGAGTCGGAGTTTGCACTGTCGGTGAGCGGCAGTCCGCAGTGGGGTGGCGGCGAGATGGCGCG
TCGTGTCGCCACGTTCGACTGGAGCGACACGCCGCTCGGGCCGCGTTCGACGTGGCCGCCGAGCCTCGCCGCCGCAGTGC
GGCTCGTGCTCGCGTCGCCGTCGCCGCTCGTGATCCTCTGGGGCCGCGAAGGCACGATGCTCTACAACGACGCCTATGCG
TCGTTTGCCGGCGGGCGCCATCCATTCCTGCTCGGCAAGCCGGTCGAGGTCGGCTGGCCCGAGGTCGCGTCGTTCAACCG
GCACGTGGTCGACACCTGTCTCGCCGGCGGCACGCTGACCTATCGCGACAAGCAGCTCGTGCTGTATCGCCAGGGCCGCC
CCGAGGACGTCTGGATGGACCTCGGCTACAGCCCCGTATTCGACGACGACGGGCAGCCGGCCGGCGTCATCGCGATCGTG
TTCGAGACGACCGCGAAGGTCGTTGCGGAGGCGCGGCGCCACGAGGCCGAATACGCGCTGATGCAGCTCACGCAGACGCT
CGAGCAGCGCGTCGCCGAAGAAGTCGCGGCGCGCGTCGCGATGGAAGCGCAACTGCGGCAGGCGCAGAAGCTCGAGGCGA
TCGGCAGCCTGACCGGCGGCGTCGCGCACGACTTCAACAACGTGCTGCAGGTGATCGCGGCGAACCTGCAGCTGATTCAG
CTGATGACGCAGGGCAACGCGGAGCTCGAACGGCGCGTCGCCGTCGCGAGCAATGCGGTGTCGCGCGGCGCGAAGCTCGC
GTCGCAGCTGCTCGCATTCGCGCGCCGGCAGCCGCTCGTGCCGACCGTGCTCAATCCGATGCGGCTCGTCGAAGCGACGG
CCGAGATGCTGCGCCGTACGTTGCCGGCGTCGATCGAGCTGTCGATCGAAGATGCGTACGCCGGCTGGCACATCTATGCG
GATCCGAACGAACTCGAAAGCGCGCTGCTGAATCTCGTGATCAATGCGCGCGACGCGATCCACGAGCGCGGCACGATCCG
CATCGCCGTGACGGCCGTCGACGCGTCGAGCGACCGCCGCGCGGCGCAGGCCGGCGTGCCGGCCGGCGACTACGTGCGGC
TGTCGGTCGCCGACGACGGTCACGGCATGCCCGAGCGCGTGAAGCTGCGCGCGTTCGAACCGTTTTTCACGACGAAGGCG
GAAGGACAGGGCACCGGTCTCGGGCTCAGCATGGTGCACGGGTTCGTCTCGCAGAGCGCCGGCTGCGTCCATATCAGCAG
CGCCGAAGGCGAGGGTACGACCGTCGATCTCTACTTTCCGCGCTGTCTCGATACGGAGCGCGAACCGGGCAAGCCCGCGA
CCGCGCCGGCCACGCGCGGCGGCGAGACGATTCTCGTCGTCGAGGACAATTGCGACGTGCGCCTCGCGGCGATCGAGATG
CTCGCGCGGCTCGGCTACAAGGTGCTGTCCGCGCAGGACGGCGATGCGGCGCTGCGCCTGATCCAGAGCGGGCAGCGCTT
CGATTTGCTGTTTACCGACGTCGTGATGCCGGGCGCCGTGCGCAGCAGCGAACTCGCGCGGATCGCGAGCGCGCCGCCGT
ACCACGCCGGCGTGCTGTTCGCGTCCGGCTATACGCGCGACATCATCTTCCATGACGGCAAGCTCGACGAAGGCGTCGCG
CTGATCGGCAAGCCTTATGCCCTCGACGATCTCGCGCGCGCCGTGCGCGACGCGCTCGATCGCCGCGCGACCGCGTGGCC
CGCATGA

Upstream 100 bases:

>100_bases
CTTGCGCCGATGCAGGCGGGACAGGCCGCCGAAGCGGCCGGCGGGCAACGGATCGACGTTGGGTCGTGCAAAAGTTTCCA
GATCGCGTGAGCGTTACCGT

Downstream 100 bases:

>100_bases
GTGCTGGCGCGTCATCTGCGCCTCGCGTCGTGGTCGTGCATCGTGTGCGGTGAATGTTCGGATTGACGAAGCGCCGACTT
TGTCCGGAACGAATGCCATT

Product: signal transduction histidine kinase

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 588; Mature: 587

Protein sequence:

>588_residues
MSEISVESEFALSVSGSPQWGGGEMARRVATFDWSDTPLGPRSTWPPSLAAAVRLVLASPSPLVILWGREGTMLYNDAYA
SFAGGRHPFLLGKPVEVGWPEVASFNRHVVDTCLAGGTLTYRDKQLVLYRQGRPEDVWMDLGYSPVFDDDGQPAGVIAIV
FETTAKVVAEARRHEAEYALMQLTQTLEQRVAEEVAARVAMEAQLRQAQKLEAIGSLTGGVAHDFNNVLQVIAANLQLIQ
LMTQGNAELERRVAVASNAVSRGAKLASQLLAFARRQPLVPTVLNPMRLVEATAEMLRRTLPASIELSIEDAYAGWHIYA
DPNELESALLNLVINARDAIHERGTIRIAVTAVDASSDRRAAQAGVPAGDYVRLSVADDGHGMPERVKLRAFEPFFTTKA
EGQGTGLGLSMVHGFVSQSAGCVHISSAEGEGTTVDLYFPRCLDTEREPGKPATAPATRGGETILVVEDNCDVRLAAIEM
LARLGYKVLSAQDGDAALRLIQSGQRFDLLFTDVVMPGAVRSSELARIASAPPYHAGVLFASGYTRDIIFHDGKLDEGVA
LIGKPYALDDLARAVRDALDRRATAWPA

Sequences:

>Translated_588_residues
MSEISVESEFALSVSGSPQWGGGEMARRVATFDWSDTPLGPRSTWPPSLAAAVRLVLASPSPLVILWGREGTMLYNDAYA
SFAGGRHPFLLGKPVEVGWPEVASFNRHVVDTCLAGGTLTYRDKQLVLYRQGRPEDVWMDLGYSPVFDDDGQPAGVIAIV
FETTAKVVAEARRHEAEYALMQLTQTLEQRVAEEVAARVAMEAQLRQAQKLEAIGSLTGGVAHDFNNVLQVIAANLQLIQ
LMTQGNAELERRVAVASNAVSRGAKLASQLLAFARRQPLVPTVLNPMRLVEATAEMLRRTLPASIELSIEDAYAGWHIYA
DPNELESALLNLVINARDAIHERGTIRIAVTAVDASSDRRAAQAGVPAGDYVRLSVADDGHGMPERVKLRAFEPFFTTKA
EGQGTGLGLSMVHGFVSQSAGCVHISSAEGEGTTVDLYFPRCLDTEREPGKPATAPATRGGETILVVEDNCDVRLAAIEM
LARLGYKVLSAQDGDAALRLIQSGQRFDLLFTDVVMPGAVRSSELARIASAPPYHAGVLFASGYTRDIIFHDGKLDEGVA
LIGKPYALDDLARAVRDALDRRATAWPA
>Mature_587_residues
SEISVESEFALSVSGSPQWGGGEMARRVATFDWSDTPLGPRSTWPPSLAAAVRLVLASPSPLVILWGREGTMLYNDAYAS
FAGGRHPFLLGKPVEVGWPEVASFNRHVVDTCLAGGTLTYRDKQLVLYRQGRPEDVWMDLGYSPVFDDDGQPAGVIAIVF
ETTAKVVAEARRHEAEYALMQLTQTLEQRVAEEVAARVAMEAQLRQAQKLEAIGSLTGGVAHDFNNVLQVIAANLQLIQL
MTQGNAELERRVAVASNAVSRGAKLASQLLAFARRQPLVPTVLNPMRLVEATAEMLRRTLPASIELSIEDAYAGWHIYAD
PNELESALLNLVINARDAIHERGTIRIAVTAVDASSDRRAAQAGVPAGDYVRLSVADDGHGMPERVKLRAFEPFFTTKAE
GQGTGLGLSMVHGFVSQSAGCVHISSAEGEGTTVDLYFPRCLDTEREPGKPATAPATRGGETILVVEDNCDVRLAAIEML
ARLGYKVLSAQDGDAALRLIQSGQRFDLLFTDVVMPGAVRSSELARIASAPPYHAGVLFASGYTRDIIFHDGKLDEGVAL
IGKPYALDDLARAVRDALDRRATAWPA

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=254, Percent_Identity=29.9212598425197, Blast_Score=103, Evalue=4e-23,
Organism=Escherichia coli, GI1788549, Length=329, Percent_Identity=28.2674772036474, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1788713, Length=223, Percent_Identity=29.1479820627803, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI145693157, Length=272, Percent_Identity=26.4705882352941, Blast_Score=66, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 63453; Mature: 63322

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEISVESEFALSVSGSPQWGGGEMARRVATFDWSDTPLGPRSTWPPSLAAAVRLVLASP
CCCCCCCCEEEEEECCCCCCCCHHHHHHHEECCCCCCCCCCCCCCCHHHHHHHHHHEECC
SPLVILWGREGTMLYNDAYASFAGGRHPFLLGKPVEVGWPEVASFNRHVVDTCLAGGTLT
CCEEEEECCCCCEEEECCHHHCCCCCCCEEECCCCCCCCCHHHHCCHHHHHHHHCCCEEE
YRDKQLVLYRQGRPEDVWMDLGYSPVFDDDGQPAGVIAIVFETTAKVVAEARRHEAEYAL
EECCEEEEEECCCCCEEEEECCCCCCCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHH
MQLTQTLEQRVAEEVAARVAMEAQLRQAQKLEAIGSLTGGVAHDFNNVLQVIAANLQLIQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
LMTQGNAELERRVAVASNAVSRGAKLASQLLAFARRQPLVPTVLNPMRLVEATAEMLRRT
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
LPASIELSIEDAYAGWHIYADPNELESALLNLVINARDAIHERGTIRIAVTAVDASSDRR
CCCEEEEEEEECCCCEEEEECHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCH
AAQAGVPAGDYVRLSVADDGHGMPERVKLRAFEPFFTTKAEGQGTGLGLSMVHGFVSQSA
HHHCCCCCCCEEEEEECCCCCCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCC
GCVHISSAEGEGTTVDLYFPRCLDTEREPGKPATAPATRGGETILVVEDNCDVRLAAIEM
CEEEEECCCCCCCEEEEEECHHCCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEHHHHHH
LARLGYKVLSAQDGDAALRLIQSGQRFDLLFTDVVMPGAVRSSELARIASAPPYHAGVLF
HHHCCHHEECCCCCHHHHHHHHCCCCEEEEEEHHHCCCCCCHHHHHHHHCCCCCCCEEEE
ASGYTRDIIFHDGKLDEGVALIGKPYALDDLARAVRDALDRRATAWPA
ECCCCEEEEEECCCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SEISVESEFALSVSGSPQWGGGEMARRVATFDWSDTPLGPRSTWPPSLAAAVRLVLASP
CCCCCCCEEEEEECCCCCCCCHHHHHHHEECCCCCCCCCCCCCCCHHHHHHHHHHEECC
SPLVILWGREGTMLYNDAYASFAGGRHPFLLGKPVEVGWPEVASFNRHVVDTCLAGGTLT
CCEEEEECCCCCEEEECCHHHCCCCCCCEEECCCCCCCCCHHHHCCHHHHHHHHCCCEEE
YRDKQLVLYRQGRPEDVWMDLGYSPVFDDDGQPAGVIAIVFETTAKVVAEARRHEAEYAL
EECCEEEEEECCCCCEEEEECCCCCCCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHH
MQLTQTLEQRVAEEVAARVAMEAQLRQAQKLEAIGSLTGGVAHDFNNVLQVIAANLQLIQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
LMTQGNAELERRVAVASNAVSRGAKLASQLLAFARRQPLVPTVLNPMRLVEATAEMLRRT
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
LPASIELSIEDAYAGWHIYADPNELESALLNLVINARDAIHERGTIRIAVTAVDASSDRR
CCCEEEEEEEECCCCEEEEECHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCH
AAQAGVPAGDYVRLSVADDGHGMPERVKLRAFEPFFTTKAEGQGTGLGLSMVHGFVSQSA
HHHCCCCCCCEEEEEECCCCCCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCC
GCVHISSAEGEGTTVDLYFPRCLDTEREPGKPATAPATRGGETILVVEDNCDVRLAAIEM
CEEEEECCCCCCCEEEEEECHHCCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEHHHHHH
LARLGYKVLSAQDGDAALRLIQSGQRFDLLFTDVVMPGAVRSSELARIASAPPYHAGVLF
HHHCCHHEECCCCCHHHHHHHHCCCCEEEEEEHHHCCCCCCHHHHHHHHCCCCCCCEEEE
ASGYTRDIIFHDGKLDEGVALIGKPYALDDLARAVRDALDRRATAWPA
ECCCCEEEEEECCCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA