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The map label for this gene is degP1 [H]

Identifier: 189353131

GI number: 189353131

Start: 1324252

End: 1326429

Strand: Reverse

Name: degP1 [H]

Synonym: BMULJ_04367

Alternate gene names: 189353131

Gene position: 1326429-1324252 (Counterclockwise)

Preceding gene: 189353132

Following gene: 189353130

Centisome position: 53.63

GC content: 74.66

Gene sequence:

>2178_bases
GTGGTCCGCCAGACGCTTGCACGCGCCGTCCTTCACGCCGCGCTGAGCGCGCTCGCGCTCGCCGTTGCCTCGCCATCGCC
GACCGCCGTCGCGGCGACGGTCGCACTGCCTGTCGACAACGGCAGCGGGCCGCCCGCCGCGTCCGACGTCGCATCGGACG
GTTTTCCGGCGATCGTCGACCGCTACGGCGCGGCGGTCGTCACGATCCGCACGAGCGCGTTCGATCCGCAGACCGGCGAG
CCGACGTTCGCCATTCTCGATCCCGACGATCCGCTCGCCGCATTCTTCCGACGCGGTGCGCCGCCGCGCGCGCAGGGCCC
GCAACCGCCTGCGCCCGATACGTCGCCGCGCGCGATCACCGGTAGCGGGTCCGGCTTCATCGTCAGCCCCGATGGCGCGA
TCCTCACGTCCGCGCACGTGATCGGCGACGCGACCGATGCGACGGTCCGGCTCGCCAATGGCCGCGAATTCCGCGCGACC
GTGGTGGCGGTCGATCCGCAGAGCGACGTCGCGGTGCTGCGGATCGACGGCACGCGGCTGCCTTATGTGCCGATTGCCGA
GGCGACGCGGGTGCGTGCCGGCGAGCCCGTGATGACGATCGGCGCGCCGGACGGCGCGGGCAACACGGTCACGGCCGGCA
TCGTCAGCGCGACGCCGCGGCGGCTGCCGGACGGCAGCGCGTTCCCGTTCCTGCAGACCGACATCGCGGTGAATCCCGAC
AACTCCGGCGGCCCGGTGTTCGATCGCGCGGGCAACGTGGTCGGTATCGCGATGCAGGTCTATACGGGCGTGGATCGCTA
CGCAAGCCTCACGTTCGCGATTCCGATCGCGCTCAGCGCGAAGCTGCGTGCCCAACTGCAGCCGCCCGCGCAGGCGGCGC
GCGGGTCGGGCGCCAATGCGCTCGGCCTCGACGTGCAGGACGTCGGCGCGGGGCTGGCCGCGGCGCTCGGGCTGCCGCGC
GCGTCGGGTGCGCTCGTCGACGGCGTCGAGGCCGGTTCGCCGGCCGCGGTGGCGGGCGTGCGTGCGGGCGACGTAATCGT
GCAGTTCGGCGATCGACCGGTCGCGGGTGCGGCCGAGCTGAACGACCTCGCGGCGACGCTCGCCCCGGGCGAGCAGGCGC
CGATGCGGCTGATTCGCAATCGCGCGCCGGTCGTGGTGACGGTCGCGGTCAACGACGACGCGGGCGCGAATGCGGTCGGC
GCCGATGGGACGAGCGGTGTCGCCGGTGCGAGCGGTGGCGAGGACGAGAGCGGGGCGGCGGGCTCGGGTGCGAATGGCTT
GGGTATGGCCGGCTCGCGCACGGGCGGGGCAGTTGCGACCAATTTGCGTGCGGCTGGTTCAGGCGCCGTCCGCGCGGCTG
GCGCCGGCTCGGGTACGGTCGGATCACGCGTCGCTGGATCGAGTGCGGCTGATCTCGGGGCCGGCCCGAGTGCGGCCCGC
TCAAGCGTGACGCACTCAGGCGCGGCCGGCTCAGGCGCGGCCGGCTCAGGCGTTGCCCGCTCAAGTACGACGCGCTCGGT
TGCCGCCGGGGCAGGCACAGCGGGCTCGAGTACGGCTCGCCCGGTCCCCGCCGACTCGGGCGCGGCCGGGGCAGGTTCAG
TCGGCTCGAGTACGACCCGCTCGGTTGCAGCGGGCTCACGCGCCGCTGGGGCAGGCGCCGCCAGCTCAAATACGACGCGC
TCGGCCACCGCCGGCGCGGCCGGTTCAGGCGCGGCCGGCATAGGCGCGGCCGGCTCGGGCGCGACCGACGCCGGCGCGCC
CGCGTTGCGCGCAGCCGGTACAGCGGGCGCGGACGGCGACGACGTCGTTCCCGCGGCAACCGCCACGCGCGCGGCACCGG
CCATGCACACGGCCGCCGCACCGGTCGGGACCGCGACCGTCACGCGTACCGCCGCGCGGCCGCCGCAGCACGGCGACCGC
CTCGGGCTGACGATGCATCCGCTGACTGACGACGAACGGCGGTCGACCGGCTTGCCCGTCGGCATGATGGTGGACGCGGT
GCGCGGCCCGGCGGCGCGTGCGGGCATCGAACCGGGCGACGTCGTGCTCGAACTGAACGACACGCTGCTCGAATCGCCGG
CCGACGTGCCGGCGCTCGAGGCGAACGGCGGCGACGTCATCGCGGTGCTGATCCAGCGCAACCACGCACGCCGGTTCGTG
TCGGTGCGCGTGCGATAG

Upstream 100 bases:

>100_bases
CGACGCGCGTGAGGTATAAATGGAGGCGTGTACCGGTGCTTGTCGGGTGTCTGCGCGTGTCGCGCAGCGCGTTGCCGCGA
CTGCCCGGGGGAGGTGCACC

Downstream 100 bases:

>100_bases
CGCGTTGACGGCGGCCGCCGCGCCTGTCTACCATCATCGCGTGCAGCGTCGCGCAGCGCCGATCCGGCCTGCGCGACCCG
TTCGGCTGCCGCTTCCCGCG

Product: putative serine protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 725; Mature: 725

Protein sequence:

>725_residues
MVRQTLARAVLHAALSALALAVASPSPTAVAATVALPVDNGSGPPAASDVASDGFPAIVDRYGAAVVTIRTSAFDPQTGE
PTFAILDPDDPLAAFFRRGAPPRAQGPQPPAPDTSPRAITGSGSGFIVSPDGAILTSAHVIGDATDATVRLANGREFRAT
VVAVDPQSDVAVLRIDGTRLPYVPIAEATRVRAGEPVMTIGAPDGAGNTVTAGIVSATPRRLPDGSAFPFLQTDIAVNPD
NSGGPVFDRAGNVVGIAMQVYTGVDRYASLTFAIPIALSAKLRAQLQPPAQAARGSGANALGLDVQDVGAGLAAALGLPR
ASGALVDGVEAGSPAAVAGVRAGDVIVQFGDRPVAGAAELNDLAATLAPGEQAPMRLIRNRAPVVVTVAVNDDAGANAVG
ADGTSGVAGASGGEDESGAAGSGANGLGMAGSRTGGAVATNLRAAGSGAVRAAGAGSGTVGSRVAGSSAADLGAGPSAAR
SSVTHSGAAGSGAAGSGVARSSTTRSVAAGAGTAGSSTARPVPADSGAAGAGSVGSSTTRSVAAGSRAAGAGAASSNTTR
SATAGAAGSGAAGIGAAGSGATDAGAPALRAAGTAGADGDDVVPAATATRAAPAMHTAAAPVGTATVTRTAARPPQHGDR
LGLTMHPLTDDERRSTGLPVGMMVDAVRGPAARAGIEPGDVVLELNDTLLESPADVPALEANGGDVIAVLIQRNHARRFV
SVRVR

Sequences:

>Translated_725_residues
MVRQTLARAVLHAALSALALAVASPSPTAVAATVALPVDNGSGPPAASDVASDGFPAIVDRYGAAVVTIRTSAFDPQTGE
PTFAILDPDDPLAAFFRRGAPPRAQGPQPPAPDTSPRAITGSGSGFIVSPDGAILTSAHVIGDATDATVRLANGREFRAT
VVAVDPQSDVAVLRIDGTRLPYVPIAEATRVRAGEPVMTIGAPDGAGNTVTAGIVSATPRRLPDGSAFPFLQTDIAVNPD
NSGGPVFDRAGNVVGIAMQVYTGVDRYASLTFAIPIALSAKLRAQLQPPAQAARGSGANALGLDVQDVGAGLAAALGLPR
ASGALVDGVEAGSPAAVAGVRAGDVIVQFGDRPVAGAAELNDLAATLAPGEQAPMRLIRNRAPVVVTVAVNDDAGANAVG
ADGTSGVAGASGGEDESGAAGSGANGLGMAGSRTGGAVATNLRAAGSGAVRAAGAGSGTVGSRVAGSSAADLGAGPSAAR
SSVTHSGAAGSGAAGSGVARSSTTRSVAAGAGTAGSSTARPVPADSGAAGAGSVGSSTTRSVAAGSRAAGAGAASSNTTR
SATAGAAGSGAAGIGAAGSGATDAGAPALRAAGTAGADGDDVVPAATATRAAPAMHTAAAPVGTATVTRTAARPPQHGDR
LGLTMHPLTDDERRSTGLPVGMMVDAVRGPAARAGIEPGDVVLELNDTLLESPADVPALEANGGDVIAVLIQRNHARRFV
SVRVR
>Mature_725_residues
MVRQTLARAVLHAALSALALAVASPSPTAVAATVALPVDNGSGPPAASDVASDGFPAIVDRYGAAVVTIRTSAFDPQTGE
PTFAILDPDDPLAAFFRRGAPPRAQGPQPPAPDTSPRAITGSGSGFIVSPDGAILTSAHVIGDATDATVRLANGREFRAT
VVAVDPQSDVAVLRIDGTRLPYVPIAEATRVRAGEPVMTIGAPDGAGNTVTAGIVSATPRRLPDGSAFPFLQTDIAVNPD
NSGGPVFDRAGNVVGIAMQVYTGVDRYASLTFAIPIALSAKLRAQLQPPAQAARGSGANALGLDVQDVGAGLAAALGLPR
ASGALVDGVEAGSPAAVAGVRAGDVIVQFGDRPVAGAAELNDLAATLAPGEQAPMRLIRNRAPVVVTVAVNDDAGANAVG
ADGTSGVAGASGGEDESGAAGSGANGLGMAGSRTGGAVATNLRAAGSGAVRAAGAGSGTVGSRVAGSSAADLGAGPSAAR
SSVTHSGAAGSGAAGSGVARSSTTRSVAAGAGTAGSSTARPVPADSGAAGAGSVGSSTTRSVAAGSRAAGAGAASSNTTR
SATAGAAGSGAAGIGAAGSGATDAGAPALRAAGTAGADGDDVVPAATATRAAPAMHTAAAPVGTATVTRTAARPPQHGDR
LGLTMHPLTDDERRSTGLPVGMMVDAVRGPAARAGIEPGDVVLELNDTLLESPADVPALEANGGDVIAVLIQRNHARRFV
SVRVR

Specific function: Protease With A Shared Specificity With Degp. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=282, Percent_Identity=32.6241134751773, Blast_Score=121, Evalue=2e-27,
Organism=Homo sapiens, GI7019477, Length=258, Percent_Identity=36.4341085271318, Blast_Score=121, Evalue=3e-27,
Organism=Homo sapiens, GI22129776, Length=267, Percent_Identity=32.5842696629214, Blast_Score=120, Evalue=6e-27,
Organism=Homo sapiens, GI24308541, Length=247, Percent_Identity=33.6032388663968, Blast_Score=117, Evalue=5e-26,
Organism=Escherichia coli, GI1789629, Length=283, Percent_Identity=35.3356890459364, Blast_Score=147, Evalue=3e-36,
Organism=Escherichia coli, GI1786356, Length=301, Percent_Identity=32.5581395348837, Blast_Score=135, Evalue=1e-32,
Organism=Escherichia coli, GI1789630, Length=282, Percent_Identity=33.6879432624113, Blast_Score=125, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24646839, Length=263, Percent_Identity=32.319391634981, Blast_Score=119, Evalue=5e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 69782; Mature: 69782

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: PS50106 PDZ ; PS00237 G_PROTEIN_RECEP_F1_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRQTLARAVLHAALSALALAVASPSPTAVAATVALPVDNGSGPPAASDVASDGFPAIVD
CCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEECCCCCCCCHHHHCCCCCHHHHH
RYGAAVVTIRTSAFDPQTGEPTFAILDPDDPLAAFFRRGAPPRAQGPQPPAPDTSPRAIT
CCCCEEEEEEECCCCCCCCCCEEEEECCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCEEE
GSGSGFIVSPDGAILTSAHVIGDATDATVRLANGREFRATVVAVDPQSDVAVLRIDGTRL
CCCCEEEECCCCCEEEEEEEECCCCCCEEEEECCCEEEEEEEEECCCCCEEEEEECCCCC
PYVPIAEATRVRAGEPVMTIGAPDGAGNTVTAGIVSATPRRLPDGSAFPFLQTDIAVNPD
CCEECCHHHHCCCCCCEEEEECCCCCCCEEEEEEEECCCCCCCCCCCCCEEEECEEECCC
NSGGPVFDRAGNVVGIAMQVYTGVDRYASLTFAIPIALSAKLRAQLQPPAQAARGSGANA
CCCCCCHHCCCCEEEEEEEEHHCHHHHEEEEEEEEEEECEEHHCCCCCHHHHHCCCCCCE
LGLDVQDVGAGLAAALGLPRASGALVDGVEAGSPAAVAGVRAGDVIVQFGDRPVAGAAEL
ECCCHHHHCCHHHHHHCCCCCCCCEEECCCCCCCCEEEECCCCCEEEEECCCCCCCHHHH
NDLAATLAPGEQAPMRLIRNRAPVVVTVAVNDDAGANAVGADGTSGVAGASGGEDESGAA
HHHHHHCCCCCHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GSGANGLGMAGSRTGGAVATNLRAAGSGAVRAAGAGSGTVGSRVAGSSAADLGAGPSAAR
CCCCCCCCCCCCCCCCEEEEEEEECCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCHHHH
SSVTHSGAAGSGAAGSGVARSSTTRSVAAGAGTAGSSTARPVPADSGAAGAGSVGSSTTR
HHCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHH
SVAAGSRAAGAGAASSNTTRSATAGAAGSGAAGIGAAGSGATDAGAPALRAAGTAGADGD
HHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCC
DVVPAATATRAAPAMHTAAAPVGTATVTRTAARPPQHGDRLGLTMHPLTDDERRSTGLPV
CCCCCCHHHHCCCHHHHHCCCCCCHHEECCCCCCCCCCCCCCEEECCCCCCHHHHCCCCH
GMMVDAVRGPAARAGIEPGDVVLELNDTLLESPADVPALEANGGDVIAVLIQRNHARRFV
HHHHHHHCCCHHHCCCCCCCEEEEECHHHHCCCCCCCEEECCCCCEEEEEEECCCCCEEE
SVRVR
EEEEC
>Mature Secondary Structure
MVRQTLARAVLHAALSALALAVASPSPTAVAATVALPVDNGSGPPAASDVASDGFPAIVD
CCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEECCCCCCCCHHHHCCCCCHHHHH
RYGAAVVTIRTSAFDPQTGEPTFAILDPDDPLAAFFRRGAPPRAQGPQPPAPDTSPRAIT
CCCCEEEEEEECCCCCCCCCCEEEEECCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCEEE
GSGSGFIVSPDGAILTSAHVIGDATDATVRLANGREFRATVVAVDPQSDVAVLRIDGTRL
CCCCEEEECCCCCEEEEEEEECCCCCCEEEEECCCEEEEEEEEECCCCCEEEEEECCCCC
PYVPIAEATRVRAGEPVMTIGAPDGAGNTVTAGIVSATPRRLPDGSAFPFLQTDIAVNPD
CCEECCHHHHCCCCCCEEEEECCCCCCCEEEEEEEECCCCCCCCCCCCCEEEECEEECCC
NSGGPVFDRAGNVVGIAMQVYTGVDRYASLTFAIPIALSAKLRAQLQPPAQAARGSGANA
CCCCCCHHCCCCEEEEEEEEHHCHHHHEEEEEEEEEEECEEHHCCCCCHHHHHCCCCCCE
LGLDVQDVGAGLAAALGLPRASGALVDGVEAGSPAAVAGVRAGDVIVQFGDRPVAGAAEL
ECCCHHHHCCHHHHHHCCCCCCCCEEECCCCCCCCEEEECCCCCEEEEECCCCCCCHHHH
NDLAATLAPGEQAPMRLIRNRAPVVVTVAVNDDAGANAVGADGTSGVAGASGGEDESGAA
HHHHHHCCCCCHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GSGANGLGMAGSRTGGAVATNLRAAGSGAVRAAGAGSGTVGSRVAGSSAADLGAGPSAAR
CCCCCCCCCCCCCCCCEEEEEEEECCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCHHHH
SSVTHSGAAGSGAAGSGVARSSTTRSVAAGAGTAGSSTARPVPADSGAAGAGSVGSSTTR
HHCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHH
SVAAGSRAAGAGAASSNTTRSATAGAAGSGAAGIGAAGSGATDAGAPALRAAGTAGADGD
HHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCC
DVVPAATATRAAPAMHTAAAPVGTATVTRTAARPPQHGDRLGLTMHPLTDDERRSTGLPV
CCCCCCHHHHCCCHHHHHCCCCCCHHEECCCCCCCCCCCCCCEEECCCCCCHHHHCCCCH
GMMVDAVRGPAARAGIEPGDVVLELNDTLLESPADVPALEANGGDVIAVLIQRNHARRFV
HHHHHHHCCCHHHCCCCCCCEEEEECHHHHCCCCCCCEEECCCCCEEEEEEECCCCCEEE
SVRVR
EEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550509; 11481430 [H]