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The map label for this gene is mdtA [H]

Identifier: 189352959

GI number: 189352959

Start: 1114893

End: 1116122

Strand: Reverse

Name: mdtA [H]

Synonym: BMULJ_04193

Alternate gene names: 189352959

Gene position: 1116122-1114893 (Counterclockwise)

Preceding gene: 189352960

Following gene: 189352958

Centisome position: 45.13

GC content: 71.38

Gene sequence:

>1230_bases
ATGGAAGAGAAACATCACAGCAGCGTCGGCATCCAGGTGGACGACCACGGGATGCACCTGCCGTCCCGCACGGCCGTGTC
GCGACGCGCGCGGATCGTGCTGATCGCGATCGGCGTGCTGCTCGCCGCGGGCGCCGCGCGCACGATCGTCGTCAACGTGC
TGAACCGCGGCCGGCTCGATGCCGTCGCCGAGCAGAACACGCGGCAATACGTGACGGTCGTGCATCCCGTCGACGCGGCA
AGCGGCGGCCGCCTGACGCTGCCGGGCACGCTGCGCGGCTACGTCGAGGCGCCGATCTACGCGCGCGCGAGCGGCTACGT
GCTGCGCTGGCACGCCGACATCGGCACGCACGTGAAGCAAGGGCAGCTGCTCGCCGAACTCGATACGCCGGAGCTCGATC
AGGAACTCGCGCAGGCCAGCGCGCAACGGCGGCAGGCACAGGCGGCGCTTGCGCTCGCAAAGACGTCGTTCGAGCGCGCG
CAGCAGTTGCGCGAGCGCGATGCGGTATCGCAGCAGGAACTCGACGACCGTCAGGGCGCGTTCAATCAAGGCACCGCGAA
TCTCGCGGCGGCCGACGCCAACGTGCGCCGGCTCACCGAGCTGAAGGGCTTCCAGCGCATCGTCGCGCCGATCGACGGCG
TCGTCACGCAGCGCAACGTCGACGTCGGCGATCTCGTCAGCTCCGGCAACGCGGGGCGCGCGCTGTTTACGGTCGTGCAG
GCCGACCGGCTGCGCCTGTACGTGCAGGTGCCGCAGGCGTACGCGCAGCAGGTGAAGGTCGGCCAGCACGTGAGCGTGTC
GCAGGCCGAGCTGCCGGGGCGCACGTTCGACGGCACGATCACGCGCACCGCGCAGGCGATCGACGTCGCGACGCGCTCGC
TGCAGGTCGAGATCACGCTGCCGAACGCCGACGAGCGGCTGCTGCCCGGCGCCTACGTGCAGGCCACGCTGCCGATGACG
CCGGTCGGCCGCCTGCAGATTCCGGCCAGCACGCTGCTGTTCCGCGCGGAAGGGCCGACGGTCGCGAGCGTCGACGCGAA
CGGCCGCGTGCATCTGAAGCCCGTGACGGTCGTGCGCACGATCGGCCAGACGCTCGAAGTCGACGGCGCGCTCACGCCGG
ACGACCGGCTCGTCGCGAACCCCGGCGATGCGCTCGCGAACGGCGACACGGTCGTCGTGTCGACGCCGACCGCGCAACCT
GCGTCGGCCGCCGCAGGAGCCCGATCGTGA

Upstream 100 bases:

>100_bases
GTTCGTGCCGCTCGTGTTCGGCGGCGTGCATGCGCGGCTCGCGCGCCGGCGCGAGCGCCGCGCGGCACCCTAACCTCTCG
CATCCTGACCGGTTGAATTC

Downstream 100 bases:

>100_bases
TCGCGACCGGCCCGCGCCGCGCCGTCGCCGCCTGCGCGATCGCGGCGGCAGCCGCCCTCGCCGGCTGCACGGTCGGCCCC
GACTACCGGCGGCCCGCGGT

Product: RND family efflux transporter MFP subunit

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 409; Mature: 409

Protein sequence:

>409_residues
MEEKHHSSVGIQVDDHGMHLPSRTAVSRRARIVLIAIGVLLAAGAARTIVVNVLNRGRLDAVAEQNTRQYVTVVHPVDAA
SGGRLTLPGTLRGYVEAPIYARASGYVLRWHADIGTHVKQGQLLAELDTPELDQELAQASAQRRQAQAALALAKTSFERA
QQLRERDAVSQQELDDRQGAFNQGTANLAAADANVRRLTELKGFQRIVAPIDGVVTQRNVDVGDLVSSGNAGRALFTVVQ
ADRLRLYVQVPQAYAQQVKVGQHVSVSQAELPGRTFDGTITRTAQAIDVATRSLQVEITLPNADERLLPGAYVQATLPMT
PVGRLQIPASTLLFRAEGPTVASVDANGRVHLKPVTVVRTIGQTLEVDGALTPDDRLVANPGDALANGDTVVVSTPTAQP
ASAAAGARS

Sequences:

>Translated_409_residues
MEEKHHSSVGIQVDDHGMHLPSRTAVSRRARIVLIAIGVLLAAGAARTIVVNVLNRGRLDAVAEQNTRQYVTVVHPVDAA
SGGRLTLPGTLRGYVEAPIYARASGYVLRWHADIGTHVKQGQLLAELDTPELDQELAQASAQRRQAQAALALAKTSFERA
QQLRERDAVSQQELDDRQGAFNQGTANLAAADANVRRLTELKGFQRIVAPIDGVVTQRNVDVGDLVSSGNAGRALFTVVQ
ADRLRLYVQVPQAYAQQVKVGQHVSVSQAELPGRTFDGTITRTAQAIDVATRSLQVEITLPNADERLLPGAYVQATLPMT
PVGRLQIPASTLLFRAEGPTVASVDANGRVHLKPVTVVRTIGQTLEVDGALTPDDRLVANPGDALANGDTVVVSTPTAQP
ASAAAGARS
>Mature_409_residues
MEEKHHSSVGIQVDDHGMHLPSRTAVSRRARIVLIAIGVLLAAGAARTIVVNVLNRGRLDAVAEQNTRQYVTVVHPVDAA
SGGRLTLPGTLRGYVEAPIYARASGYVLRWHADIGTHVKQGQLLAELDTPELDQELAQASAQRRQAQAALALAKTSFERA
QQLRERDAVSQQELDDRQGAFNQGTANLAAADANVRRLTELKGFQRIVAPIDGVVTQRNVDVGDLVSSGNAGRALFTVVQ
ADRLRLYVQVPQAYAQQVKVGQHVSVSQAELPGRTFDGTITRTAQAIDVATRSLQVEITLPNADERLLPGAYVQATLPMT
PVGRLQIPASTLLFRAEGPTVASVDANGRVHLKPVTVVRTIGQTLEVDGALTPDDRLVANPGDALANGDTVVVSTPTAQP
ASAAAGARS

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=356, Percent_Identity=28.6516853932584, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI1789929, Length=308, Percent_Identity=26.6233766233766, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1786668, Length=309, Percent_Identity=28.8025889967638, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI87081796, Length=207, Percent_Identity=29.4685990338164, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1789665, Length=398, Percent_Identity=25.8793969849246, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 43528; Mature: 43528

Theoretical pI: Translated: 8.82; Mature: 8.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
0.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEEKHHSSVGIQVDDHGMHLPSRTAVSRRARIVLIAIGVLLAAGAARTIVVNVLNRGRLD
CCCCCCCCCCEEECCCCCCCCCHHHHHHCCEEEEHHHHHHHHCCCHHEEHEEHHCCCCHH
AVAEQNTRQYVTVVHPVDAASGGRLTLPGTLRGYVEAPIYARASGYVLRWHADIGTHVKQ
HHHHCCCCEEEEEEEECCCCCCCEEECCHHHCCEECCCEEEECCCEEEEEECCCCCCCCC
GQLLAELDTPELDQELAQASAQRRQAQAALALAKTSFERAQQLRERDAVSQQELDDRQGA
CCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCC
FNQGTANLAAADANVRRLTELKGFQRIVAPIDGVVTQRNVDVGDLVSSGNAGRALFTVVQ
CCCCCCCEEECCCHHHHHHHHHHHHHHHHHHCCEEEECCCCHHHHHCCCCCCCEEEEEEE
ADRLRLYVQVPQAYAQQVKVGQHVSVSQAELPGRTFDGTITRTAQAIDVATRSLQVEITL
CCEEEEEEECCHHHHHHHHCCCCCCCCHHHCCCCCCCCCHHHHHHHHHEEEEEEEEEEEC
PNADERLLPGAYVQATLPMTPVGRLQIPASTLLFRAEGPTVASVDANGRVHLKPVTVVRT
CCCCCCCCCCCEEEEECCCCCCCCEECCHHHEEEEECCCEEEEECCCCEEEEEHHHHHHH
IGQTLEVDGALTPDDRLVANPGDALANGDTVVVSTPTAQPASAAAGARS
CCCCEEECCCCCCCCCEEECCCCCCCCCCEEEEECCCCCCCCCCCCCCC
>Mature Secondary Structure
MEEKHHSSVGIQVDDHGMHLPSRTAVSRRARIVLIAIGVLLAAGAARTIVVNVLNRGRLD
CCCCCCCCCCEEECCCCCCCCCHHHHHHCCEEEEHHHHHHHHCCCHHEEHEEHHCCCCHH
AVAEQNTRQYVTVVHPVDAASGGRLTLPGTLRGYVEAPIYARASGYVLRWHADIGTHVKQ
HHHHCCCCEEEEEEEECCCCCCCEEECCHHHCCEECCCEEEECCCEEEEEECCCCCCCCC
GQLLAELDTPELDQELAQASAQRRQAQAALALAKTSFERAQQLRERDAVSQQELDDRQGA
CCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCC
FNQGTANLAAADANVRRLTELKGFQRIVAPIDGVVTQRNVDVGDLVSSGNAGRALFTVVQ
CCCCCCCEEECCCHHHHHHHHHHHHHHHHHHCCEEEECCCCHHHHHCCCCCCCEEEEEEE
ADRLRLYVQVPQAYAQQVKVGQHVSVSQAELPGRTFDGTITRTAQAIDVATRSLQVEITL
CCEEEEEEECCHHHHHHHHCCCCCCCCHHHCCCCCCCCCHHHHHHHHHEEEEEEEEEEEC
PNADERLLPGAYVQATLPMTPVGRLQIPASTLLFRAEGPTVASVDANGRVHLKPVTVVRT
CCCCCCCCCCCEEEEECCCCCCCCEECCHHHEEEEECCCEEEEECCCCEEEEEHHHHHHH
IGQTLEVDGALTPDDRLVANPGDALANGDTVVVSTPTAQPASAAAGARS
CCCCEEECCCCCCCCCEEECCCCCCCCCCEEEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA