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The map label for this gene is hpaF [H]

Identifier: 189352902

GI number: 189352902

Start: 1049510

End: 1049902

Strand: Direct

Name: hpaF [H]

Synonym: BMULJ_04136

Alternate gene names: 189352902

Gene position: 1049510-1049902 (Clockwise)

Preceding gene: 189352901

Following gene: 189352903

Centisome position: 42.44

GC content: 65.14

Gene sequence:

>393_bases
ATGCCGCACATCGTCGTCGAATATACGGCGAACATCCGCGCCGACGCCCGCATCCCCGAGCTGCTGCGCACGATCAACGC
GACGCTGATCGCGCAGGGCGGCGTGTTTCCGATCGGCGGGATTCGTTCGCGCGCGATCGAGCTGCACGACTACTGCGTGG
CCGACGGCACCGAAGACGACGCGTTCGTCCACGTGACGCTGAAGATCGGCGCCGGGCGCAGCGAGGCGACGAAGCGCGCC
GCATGCGACGCGTTGTTCGACGCGATCAAGGCGCATTTCGCCGCGCTGTATGCGAAGCGTTATCTCGCGCTGTCGATGGA
GCTGACCGAGTTCAGCGAAAGCGGCTCGTACAAGCACAACAACATCCACGCCCGCTACAAGCGGGCCGACTGA

Upstream 100 bases:

>100_bases
TCGTCACCGACTACTTCGCGAGTTCGGGCACCGGCCAGATCAACGCCATTTTTCCGCTGCGCTGAACGCGCGCGCATCCG
ACATCCGACCGGAGACTGCC

Downstream 100 bases:

>100_bases
ATCCGAACCCCATCATGCTCGATACCGCCACCATCGATGCGCTCGCGCAGCGTCTGCACGACGCCGAACGCGAACGCACG
CAGATCCGCCAGATCTCGCT

Product: 5-carboxymethyl-2-hydroxymuconate isomerase

Products: NA

Alternate protein names: 5-carboxymethyl-2-hydroxymuconic acid isomerase; CHM isomerase; CHMI [H]

Number of amino acids: Translated: 130; Mature: 129

Protein sequence:

>130_residues
MPHIVVEYTANIRADARIPELLRTINATLIAQGGVFPIGGIRSRAIELHDYCVADGTEDDAFVHVTLKIGAGRSEATKRA
ACDALFDAIKAHFAALYAKRYLALSMELTEFSESGSYKHNNIHARYKRAD

Sequences:

>Translated_130_residues
MPHIVVEYTANIRADARIPELLRTINATLIAQGGVFPIGGIRSRAIELHDYCVADGTEDDAFVHVTLKIGAGRSEATKRA
ACDALFDAIKAHFAALYAKRYLALSMELTEFSESGSYKHNNIHARYKRAD
>Mature_129_residues
PHIVVEYTANIRADARIPELLRTINATLIAQGGVFPIGGIRSRAIELHDYCVADGTEDDAFVHVTLKIGAGRSEATKRAA
CDALFDAIKAHFAALYAKRYLALSMELTEFSESGSYKHNNIHARYKRAD

Specific function: Transforms 5-carboxymethyl-2-hydroxy-muconic acid (CHM) into 5-oxo-pent-3-ene-1,2,5-tricarboxylic acid (OPET) [H]

COG id: COG3232

COG function: function code E; 5-carboxymethyl-2-hydroxymuconate isomerase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004220
- InterPro:   IPR014347 [H]

Pfam domain/function: PF02962 CHMI [H]

EC number: =5.3.3.10 [H]

Molecular weight: Translated: 14335; Mature: 14204

Theoretical pI: Translated: 7.66; Mature: 7.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPHIVVEYTANIRADARIPELLRTINATLIAQGGVFPIGGIRSRAIELHDYCVADGTEDD
CCEEEEEEECCCCCCCHHHHHHHHHHHHEEECCCCCCCCCCCHHEEEEEEEEECCCCCCC
AFVHVTLKIGAGRSEATKRAACDALFDAIKAHFAALYAKRYLALSMELTEFSESGSYKHN
EEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHCCCCCCCCC
NIHARYKRAD
CEEEEEECCC
>Mature Secondary Structure 
PHIVVEYTANIRADARIPELLRTINATLIAQGGVFPIGGIRSRAIELHDYCVADGTEDD
CEEEEEEECCCCCCCHHHHHHHHHHHHEEECCCCCCCCCCCHHEEEEEEEEECCCCCCC
AFVHVTLKIGAGRSEATKRAACDALFDAIKAHFAALYAKRYLALSMELTEFSESGSYKHN
EEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHCCCCCCCCC
NIHARYKRAD
CEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2194841; 2261999; 8547259 [H]