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The map label for this gene is gsiC [H]

Identifier: 189352850

GI number: 189352850

Start: 976508

End: 977428

Strand: Direct

Name: gsiC [H]

Synonym: BMULJ_04084

Alternate gene names: 189352850

Gene position: 976508-977428 (Clockwise)

Preceding gene: 189352849

Following gene: 189352851

Centisome position: 39.48

GC content: 65.69

Gene sequence:

>921_bases
ATGCTGACTTTCATCATCAAACGGCTGTTCGGCCTGCTGCCCACGCTCGCGATCGTCGCGGTGCTCGTGTTTCTGTTCGT
GCATCTGCTGCCGGGCGACCCGGCGCGGCTCGCGGCCGGCCCCGAGGCCGACGAAGCGACGGTCGCGCTCGTGCGCGCCG
ATCTCGGCCTCGATCGGCCGCTGCCCACGCAGTTCGCGAATTTCTTCGTGAAGATCGCACACGGCGATTTCGGCGTATCG
ACGCGCAGCAAGCGGCCGGTATCGACGGAAATCGGCGAGCGCTTCATGCCGACGCTGATGCTGACGATCGTCAGCATGGC
GTGGGCGACGCTGTTCGGGATGGCGATCGGCATCGCGTCGGCCGTATGGCGCAACCGCTGGCCGGACCGGCTCGGCATGA
CGCTCGCGGTGTCCGGCATCTCGTTTCCGGCGTTCGCGCTCGGCATGCTCTTGATGGAGATCTTCTCGGTGAAGCTCGGC
TGGCTGCCCGTCGTGCCGGACGACACGTGGAAGAGCTACGTGCTGCCGTCGCTCACGCTCGGCGCGGCGGTCGCGGCCGT
GATGGCGCGCTTCACGCGCGCGTCGTTCGTCGAGGTGATGAACGAGGACTTCGTGCGCACCGCGCGCGCGAAGGGTGTGC
ACGAGCCGAAGGTCGTGCTCAAACACTGCCTGCGCAACGCGATGATTCCGGTCGTCACGATGATGGGGCTGCAGTTCGGC
TTCCTGCTCGGCGGGTCGATCGTCGTCGAGGCCGTGTTCAACTGGCCGGGGCTCGGCCGGCTGCTCGTCGATTCGGTGAC
GATGCGCGATTACCCGGTGATCCAGGCGATCGTGCTGCTGTTCTCGCTCGAATTCATCCTGATCAACCTGACCGTCGACG
TGCTCTACGCGGTCATCAATCCGACCATCCGGTTCAAGTGA

Upstream 100 bases:

>100_bases
ATCGACGAGGTCTCGATGAACTGAGCGCGCTCGCGCGCATCGCGGCTTGCCGGCGCAGCGCGTCGATCGCGCCGGCAAGC
GGCCCCTGTCCGGTGTCCCC

Downstream 100 bases:

>100_bases
GGTGCGCATGAACGCAACCGTTCCAGGCCCGACCGCGCCCGCCGAAACCGCCGTGCGCACGCCGTGGCGCGAATTCTGGC
GCAAGTTCCGCAAGCAGACC

Product: peptide/nickel transport system permease protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MLTFIIKRLFGLLPTLAIVAVLVFLFVHLLPGDPARLAAGPEADEATVALVRADLGLDRPLPTQFANFFVKIAHGDFGVS
TRSKRPVSTEIGERFMPTLMLTIVSMAWATLFGMAIGIASAVWRNRWPDRLGMTLAVSGISFPAFALGMLLMEIFSVKLG
WLPVVPDDTWKSYVLPSLTLGAAVAAVMARFTRASFVEVMNEDFVRTARAKGVHEPKVVLKHCLRNAMIPVVTMMGLQFG
FLLGGSIVVEAVFNWPGLGRLLVDSVTMRDYPVIQAIVLLFSLEFILINLTVDVLYAVINPTIRFK

Sequences:

>Translated_306_residues
MLTFIIKRLFGLLPTLAIVAVLVFLFVHLLPGDPARLAAGPEADEATVALVRADLGLDRPLPTQFANFFVKIAHGDFGVS
TRSKRPVSTEIGERFMPTLMLTIVSMAWATLFGMAIGIASAVWRNRWPDRLGMTLAVSGISFPAFALGMLLMEIFSVKLG
WLPVVPDDTWKSYVLPSLTLGAAVAAVMARFTRASFVEVMNEDFVRTARAKGVHEPKVVLKHCLRNAMIPVVTMMGLQFG
FLLGGSIVVEAVFNWPGLGRLLVDSVTMRDYPVIQAIVLLFSLEFILINLTVDVLYAVINPTIRFK
>Mature_306_residues
MLTFIIKRLFGLLPTLAIVAVLVFLFVHLLPGDPARLAAGPEADEATVALVRADLGLDRPLPTQFANFFVKIAHGDFGVS
TRSKRPVSTEIGERFMPTLMLTIVSMAWATLFGMAIGIASAVWRNRWPDRLGMTLAVSGISFPAFALGMLLMEIFSVKLG
WLPVVPDDTWKSYVLPSLTLGAAVAAVMARFTRASFVEVMNEDFVRTARAKGVHEPKVVLKHCLRNAMIPVVTMMGLQFG
FLLGGSIVVEAVFNWPGLGRLLVDSVTMRDYPVIQAIVLLFSLEFILINLTVDVLYAVINPTIRFK

Specific function: Part of the ABC transporter complex gsiABCD involved in glutathione import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787053, Length=306, Percent_Identity=75.8169934640523, Blast_Score=472, Evalue=1e-134,
Organism=Escherichia coli, GI1789965, Length=338, Percent_Identity=41.1242603550296, Blast_Score=246, Evalue=2e-66,
Organism=Escherichia coli, GI1789888, Length=308, Percent_Identity=37.012987012987, Blast_Score=200, Evalue=1e-52,
Organism=Escherichia coli, GI1787761, Length=329, Percent_Identity=38.6018237082067, Blast_Score=191, Evalue=4e-50,
Organism=Escherichia coli, GI1787497, Length=313, Percent_Identity=35.4632587859425, Blast_Score=184, Evalue=8e-48,
Organism=Escherichia coli, GI1787550, Length=265, Percent_Identity=31.3207547169811, Blast_Score=148, Evalue=5e-37,
Organism=Escherichia coli, GI1788504, Length=363, Percent_Identity=25.6198347107438, Blast_Score=108, Evalue=3e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 33606; Mature: 33606

Theoretical pI: Translated: 10.10; Mature: 10.10

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTFIIKRLFGLLPTLAIVAVLVFLFVHLLPGDPARLAAGPEADEATVALVRADLGLDRP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCCCHHHHHHHHHHCCCCCC
LPTQFANFFVKIAHGDFGVSTRSKRPVSTEIGERFMPTLMLTIVSMAWATLFGMAIGIAS
CHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVWRNRWPDRLGMTLAVSGISFPAFALGMLLMEIFSVKLGWLPVVPDDTWKSYVLPSLTL
HHHHCCCCHHHCCEEEECCCCHHHHHHHHHHHHHHHHHHCCEECCCCCCHHHHHCCHHHH
GAAVAAVMARFTRASFVEVMNEDFVRTARAKGVHEPKVVLKHCLRNAMIPVVTMMGLQFG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
FLLGGSIVVEAVFNWPGLGRLLVDSVTMRDYPVIQAIVLLFSLEFILINLTVDVLYAVIN
HHHCCHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PTIRFK
CCCCCC
>Mature Secondary Structure
MLTFIIKRLFGLLPTLAIVAVLVFLFVHLLPGDPARLAAGPEADEATVALVRADLGLDRP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCCCHHHHHHHHHHCCCCCC
LPTQFANFFVKIAHGDFGVSTRSKRPVSTEIGERFMPTLMLTIVSMAWATLFGMAIGIAS
CHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVWRNRWPDRLGMTLAVSGISFPAFALGMLLMEIFSVKLGWLPVVPDDTWKSYVLPSLTL
HHHHCCCCHHHCCEEEECCCCHHHHHHHHHHHHHHHHHHCCEECCCCCCHHHHHCCHHHH
GAAVAAVMARFTRASFVEVMNEDFVRTARAKGVHEPKVVLKHCLRNAMIPVVTMMGLQFG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
FLLGGSIVVEAVFNWPGLGRLLVDSVTMRDYPVIQAIVLLFSLEFILINLTVDVLYAVIN
HHHCCHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PTIRFK
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA