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The map label for this gene is ycgM [C]

Identifier: 189352834

GI number: 189352834

Start: 957363

End: 958061

Strand: Direct

Name: ycgM [C]

Synonym: BMULJ_04068

Alternate gene names: 189352834

Gene position: 957363-958061 (Clockwise)

Preceding gene: 189352833

Following gene: 189352835

Centisome position: 38.71

GC content: 67.1

Gene sequence:

>699_bases
ATGACTTTCGTTTTCCCGCCCGAAGCGCCGGTCGCACTTCCTGTCGCCGGCAGCGATGCCCGTTTTCCGGTGCGCCGCGT
CTACTGCGTCGGCCGCAACTATGCCGCCCATGCGCGCGAGATGGGCTTCGATCCCGACCGCGAGCCGCCGTTCTTCTTCT
GCAAGCCGGCCGACGCCGTCGTGCCGGTCGCATACGGCGAAACGCTCGAACTCGCGTATCCGTCGCAGACGCAGAACTAT
CACTACGAAGCCGAACTCGTCGCGGTGATCGGCAAGGGCGGGGCCGACATTCCGCTCGACAGCGCGCTCGACCACGTGTG
GGGCTATGCGGTCGGCCTCGACATGACGCGCCGCGACCTGCAGATGAAGATGCGCGAGATGGGCCGCCCGTGGGAAATCG
GCAAGGCGTTCGACCGGTCTGCGCCGATCGGCCCGGTGCATCGGGCCAGCGAAGTCGGCCATTTCGAACAGGGCGGCCTG
TGGCTGACCGTCAACGGTGCCACGAAGCAGCAGAGCGACGTGTCGCACCTGATCTGGTCGGTCGCGGAGACGGTCGCGGA
CCTGTCGAAGTTTTTCCGCCTCGAACCGGGCGACGTGATCTTTACCGGCACGCCGGAAGGCGTCGGCGCGGTCGTGCGCG
GCGACGAGATGAAGGTCGGGGTCGAGCGGCTCGGCGAACTCACCGTGCGCGTCGTCTGA

Upstream 100 bases:

>100_bases
CTGCCGCCTCGCGGTCAGTCGATTCGTTTCGATTCGTTTCGTGCGCCGCGCAAGCGGCGCGTACCCCTCACTCGTTGTTC
AAGCTGGAGCCGTTCCGATC

Downstream 100 bases:

>100_bases
CGCCCGTTTTCGAAAGGTCCCATCGTGCAACTGCATAGCTTCTTCAACAGTTCGACCTCCTATCGGGTGCGTATCGCGCT
TGCGCTGAAAGGGCTGCCGT

Product: acylpyruvate hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 232; Mature: 231

Protein sequence:

>232_residues
MTFVFPPEAPVALPVAGSDARFPVRRVYCVGRNYAAHAREMGFDPDREPPFFFCKPADAVVPVAYGETLELAYPSQTQNY
HYEAELVAVIGKGGADIPLDSALDHVWGYAVGLDMTRRDLQMKMREMGRPWEIGKAFDRSAPIGPVHRASEVGHFEQGGL
WLTVNGATKQQSDVSHLIWSVAETVADLSKFFRLEPGDVIFTGTPEGVGAVVRGDEMKVGVERLGELTVRVV

Sequences:

>Translated_232_residues
MTFVFPPEAPVALPVAGSDARFPVRRVYCVGRNYAAHAREMGFDPDREPPFFFCKPADAVVPVAYGETLELAYPSQTQNY
HYEAELVAVIGKGGADIPLDSALDHVWGYAVGLDMTRRDLQMKMREMGRPWEIGKAFDRSAPIGPVHRASEVGHFEQGGL
WLTVNGATKQQSDVSHLIWSVAETVADLSKFFRLEPGDVIFTGTPEGVGAVVRGDEMKVGVERLGELTVRVV
>Mature_231_residues
TFVFPPEAPVALPVAGSDARFPVRRVYCVGRNYAAHAREMGFDPDREPPFFFCKPADAVVPVAYGETLELAYPSQTQNYH
YEAELVAVIGKGGADIPLDSALDHVWGYAVGLDMTRRDLQMKMREMGRPWEIGKAFDRSAPIGPVHRASEVGHFEQGGLW
LTVNGATKQQSDVSHLIWSVAETVADLSKFFRLEPGDVIFTGTPEGVGAVVRGDEMKVGVERLGELTVRVV

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI13654274, Length=207, Percent_Identity=39.1304347826087, Blast_Score=152, Evalue=2e-37,
Organism=Homo sapiens, GI66348062, Length=200, Percent_Identity=39.5, Blast_Score=149, Evalue=1e-36,
Organism=Homo sapiens, GI215422413, Length=204, Percent_Identity=38.7254901960784, Blast_Score=149, Evalue=2e-36,
Organism=Homo sapiens, GI156231349, Length=215, Percent_Identity=35.3488372093023, Blast_Score=124, Evalue=5e-29,
Organism=Homo sapiens, GI40786394, Length=215, Percent_Identity=34.8837209302326, Blast_Score=121, Evalue=4e-28,
Organism=Escherichia coli, GI1787428, Length=217, Percent_Identity=39.63133640553, Blast_Score=145, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI17557057, Length=196, Percent_Identity=35.7142857142857, Blast_Score=128, Evalue=3e-30,
Organism=Saccharomyces cerevisiae, GI6324161, Length=221, Percent_Identity=27.1493212669683, Blast_Score=109, Evalue=4e-25,
Organism=Drosophila melanogaster, GI28571789, Length=209, Percent_Identity=33.0143540669856, Blast_Score=109, Evalue=1e-24,
Organism=Drosophila melanogaster, GI28572127, Length=216, Percent_Identity=34.2592592592593, Blast_Score=107, Evalue=5e-24,
Organism=Drosophila melanogaster, GI24663695, Length=222, Percent_Identity=27.9279279279279, Blast_Score=81, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: NA

Molecular weight: Translated: 25477; Mature: 25346

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFVFPPEAPVALPVAGSDARFPVRRVYCVGRNYAAHAREMGFDPDREPPFFFCKPADAV
CEEECCCCCCEEEEECCCCCCCCEEEEEEECCCHHHHHHHCCCCCCCCCCEEEECCCCCE
VPVAYGETLELAYPSQTQNYHYEAELVAVIGKGGADIPLDSALDHVWGYAVGLDMTRRDL
EEEECCCEEEEECCCCCCCEEEEEEEEEEEECCCCCCCHHHHHHHHHHHHHCCCHHHHHH
QMKMREMGRPWEIGKAFDRSAPIGPVHRASEVGHFEQGGLWLTVNGATKQQSDVSHLIWS
HHHHHHCCCCCCHHHHHCCCCCCCCCHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHH
VAETVADLSKFFRLEPGDVIFTGTPEGVGAVVRGDEMKVGVERLGELTVRVV
HHHHHHHHHHHHCCCCCCEEEECCCCCCEEEEECCCHHHHHHHHCCEEEEEC
>Mature Secondary Structure 
TFVFPPEAPVALPVAGSDARFPVRRVYCVGRNYAAHAREMGFDPDREPPFFFCKPADAV
EEECCCCCCEEEEECCCCCCCCEEEEEEECCCHHHHHHHCCCCCCCCCCEEEECCCCCE
VPVAYGETLELAYPSQTQNYHYEAELVAVIGKGGADIPLDSALDHVWGYAVGLDMTRRDL
EEEECCCEEEEECCCCCCCEEEEEEEEEEEECCCCCCCHHHHHHHHHHHHHCCCHHHHHH
QMKMREMGRPWEIGKAFDRSAPIGPVHRASEVGHFEQGGLWLTVNGATKQQSDVSHLIWS
HHHHHHCCCCCCHHHHHCCCCCCCCCHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHH
VAETVADLSKFFRLEPGDVIFTGTPEGVGAVVRGDEMKVGVERLGELTVRVV
HHHHHHHHHHHHCCCCCCEEEECCCCCCEEEEECCCHHHHHHHHCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12622808 [H]