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The map label for this gene is pip [H]

Identifier: 189352804

GI number: 189352804

Start: 923720

End: 924652

Strand: Reverse

Name: pip [H]

Synonym: BMULJ_04036

Alternate gene names: 189352804

Gene position: 924652-923720 (Counterclockwise)

Preceding gene: 189352805

Following gene: 189352798

Centisome position: 37.39

GC content: 67.31

Gene sequence:

>933_bases
ATGTATCCACCGATCGAACCCTACGCCCACGGCTATCTCGACACCGACGATGGCCATCGCATCTATTGGGAGCGCTGCGG
CAATCCGGCCGGCAAGCCCGCCGTGTTCCTGCACGGCGGCCCCGGCGCCGGTTGCAGCGCCGACCATCGCCGGCTATTCG
ACCCGCAGCGCTACGACGTGCTGCTGTTCGATCAGCGCGGCTGCGGACGCTCGACGCCGCATGCGAGCCTCGACAACAAC
ACGACCTGGCATCTGGTCGCGGACATCGAACGTCTGCGCGAGATGGTCGGCGCCGAACAGTGGCTCGTGTTCGGCGGCTC
GTGGGGCAGCGCGCTCGGTCTCGCATATGCGGAAACGCATCCGGCGCGCGTCAGCGCACTGATCGTGCGCGGCATCTTCA
CGATGCGACGCGCCGAGCTGCTGTGGTACTACCAGGAAGGTGCCTCGTGGCTGTTTCCCGATCTGTGGGAAGCATTCATC
GCGCCGATTCCACCGGCGGAGCGCGGCGATCTGATGGCCGCCTACCATCGACGGCTGACGGGCGACGACGAAACGGCCAA
GCTCGAGGCCGCCCGTGCGTGGAGCGTGTGGGAAGGCCGCACGATCACGCTGCTGCCCGATCCGGCACTCGCTGAGCATT
TCGCGGACGGCCACTACGCGCTCGCGTTCGCGCGCATCGAGAATCATTACTTCGTGAATCGCGGCTTCGTCGACGAAGGG
CAGCTGCTGCGCGACGCGCATCGCCTCGCGGGCATTCCCGGCGTGATCGTTCAGGGGCGTTACGACATCGCGACGCCGGC
GCGCACCGCGTGGGAGCTGTCGAAGGCGTGGCCCGACGCGACGCTGGAAATCGTGCCCGACGCCGGGCATGCATACAACG
AACCGGGCATCCTCAGCGCGCTGCTCGCGGCGACCGACCGCTTCGCCATGTAA

Upstream 100 bases:

>100_bases
CGCGCCGCTCACCTCGCTGCGGCTTCCCGGTTTTTTCCCGCCGAACACACCGCGGCCATTTCACGCATAATGCCTGCGAC
CCGTTCACGACGAGCCGCCC

Downstream 100 bases:

>100_bases
TTCACGCACGGACGCGCGCGGCACGATGCGGCACCGCGCGCGCCACGCAAGCGCGCACACGACGTCGTCACAGCGACGCC
TCCACTACCGTTCTCCCGCG

Product: proline iminopeptidase

Products: NA

Alternate protein names: PIP; Prolyl aminopeptidase; PAP [H]

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MYPPIEPYAHGYLDTDDGHRIYWERCGNPAGKPAVFLHGGPGAGCSADHRRLFDPQRYDVLLFDQRGCGRSTPHASLDNN
TTWHLVADIERLREMVGAEQWLVFGGSWGSALGLAYAETHPARVSALIVRGIFTMRRAELLWYYQEGASWLFPDLWEAFI
APIPPAERGDLMAAYHRRLTGDDETAKLEAARAWSVWEGRTITLLPDPALAEHFADGHYALAFARIENHYFVNRGFVDEG
QLLRDAHRLAGIPGVIVQGRYDIATPARTAWELSKAWPDATLEIVPDAGHAYNEPGILSALLAATDRFAM

Sequences:

>Translated_310_residues
MYPPIEPYAHGYLDTDDGHRIYWERCGNPAGKPAVFLHGGPGAGCSADHRRLFDPQRYDVLLFDQRGCGRSTPHASLDNN
TTWHLVADIERLREMVGAEQWLVFGGSWGSALGLAYAETHPARVSALIVRGIFTMRRAELLWYYQEGASWLFPDLWEAFI
APIPPAERGDLMAAYHRRLTGDDETAKLEAARAWSVWEGRTITLLPDPALAEHFADGHYALAFARIENHYFVNRGFVDEG
QLLRDAHRLAGIPGVIVQGRYDIATPARTAWELSKAWPDATLEIVPDAGHAYNEPGILSALLAATDRFAM
>Mature_310_residues
MYPPIEPYAHGYLDTDDGHRIYWERCGNPAGKPAVFLHGGPGAGCSADHRRLFDPQRYDVLLFDQRGCGRSTPHASLDNN
TTWHLVADIERLREMVGAEQWLVFGGSWGSALGLAYAETHPARVSALIVRGIFTMRRAELLWYYQEGASWLFPDLWEAFI
APIPPAERGDLMAAYHRRLTGDDETAKLEAARAWSVWEGRTITLLPDPALAEHFADGHYALAFARIENHYFVNRGFVDEG
QLLRDAHRLAGIPGVIVQGRYDIATPARTAWELSKAWPDATLEIVPDAGHAYNEPGILSALLAATDRFAM

Specific function: Specifically catalyzes the removal of N-terminal proline residues from peptides [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S33 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR005944
- InterPro:   IPR002410 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.4.11.5 [H]

Molecular weight: Translated: 34578; Mature: 34578

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYPPIEPYAHGYLDTDDGHRIYWERCGNPAGKPAVFLHGGPGAGCSADHRRLFDPQRYDV
CCCCCCCHHCCCCCCCCCCEEEEECCCCCCCCCEEEEECCCCCCCCCCHHHCCCCCCCEE
LLFDQRGCGRSTPHASLDNNTTWHLVADIERLREMVGAEQWLVFGGSWGSALGLAYAETH
EEECCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHCCCEEEEEECCCCHHHEEEHHCCC
PARVSALIVRGIFTMRRAELLWYYQEGASWLFPDLWEAFIAPIPPAERGDLMAAYHRRLT
CHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHCC
GDDETAKLEAARAWSVWEGRTITLLPDPALAEHFADGHYALAFARIENHYFVNRGFVDEG
CCCHHHHHHHHHEEEEECCCEEEEECCHHHHHHHCCCCEEEEEEEECCEEEEECCCCCCH
QLLRDAHRLAGIPGVIVQGRYDIATPARTAWELSKAWPDATLEIVPDAGHAYNEPGILSA
HHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHH
LLAATDRFAM
HHHHHHHCCC
>Mature Secondary Structure
MYPPIEPYAHGYLDTDDGHRIYWERCGNPAGKPAVFLHGGPGAGCSADHRRLFDPQRYDV
CCCCCCCHHCCCCCCCCCCEEEEECCCCCCCCCEEEEECCCCCCCCCCHHHCCCCCCCEE
LLFDQRGCGRSTPHASLDNNTTWHLVADIERLREMVGAEQWLVFGGSWGSALGLAYAETH
EEECCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHCCCEEEEEECCCCHHHEEEHHCCC
PARVSALIVRGIFTMRRAELLWYYQEGASWLFPDLWEAFIAPIPPAERGDLMAAYHRRLT
CHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHCC
GDDETAKLEAARAWSVWEGRTITLLPDPALAEHFADGHYALAFARIENHYFVNRGFVDEG
CCCHHHHHHHHHEEEEECCCEEEEECCHHHHHHHCCCCEEEEEEEECCEEEEECCCCCCH
QLLRDAHRLAGIPGVIVQGRYDIATPARTAWELSKAWPDATLEIVPDAGHAYNEPGILSA
HHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHH
LLAATDRFAM
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9348090; 11011150; 10467172 [H]