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The map label for this gene is phnW [H]

Identifier: 189352805

GI number: 189352805

Start: 924853

End: 925917

Strand: Reverse

Name: phnW [H]

Synonym: BMULJ_04037

Alternate gene names: 189352805

Gene position: 925917-924853 (Counterclockwise)

Preceding gene: 189352806

Following gene: 189352804

Centisome position: 37.44

GC content: 68.17

Gene sequence:

>1065_bases
ATGCTGCTGCTGAATCCCGGCCCGGTCACGCTCACCGAACGCGTGCGCCGCAGCCTGCTGCAACCGGACCTATGCCATCG
CGAAAGCGAGTTCTTCGATCTGCAGGACGAGGCGCGCGCGCGTCTCGTCGCCGCATACGAACTCGATCCGGCCGAATGGA
CCGCCGTGCTGATGACCGGTTCGGGCACGGCCGCCGTCGAAAGCATGATTGCCGCGCTCGTGCCGAAGGACGGCAAGCTG
CTCGTGATCGAAAACGGCGTGTACGGCGAGCGCATCACGCAGATCGCGACGCAGTACGGGATCGCACATGACGTGCTCAA
GCACGAATGGATGCAGGCGCCCGATCTCGCGCAGATCGCTGCGCGGCTCGACGCAGGCGGCTACTCGCACGTCGCGGTGA
TCCATCACGAGACGACGACCGGCCGCCTGAACGATCTCGGCGCGATCGCCGAGGTCTGTCGCGCACGAGGCGTGAAGCTG
CTCGTCGACGGCGTCAGCAGTTTCGGCGCGGAAGCGATCGACTTCGCGGGCGGCGACATCGATGCCGTCGCGGCGACCGC
GAACAAGTGCCTGCACGGCGTGCCGGGTGCCGCGTTCGTGATCGTGCGCCGCAGCGCGCTCGCGAGCGCCGCGAGCCGCA
CCTACTATCTCGACCTCGGCCGTCTCGCGAAGCTGCAGGATCAGCGCAACACGCCGTTCACGCCGTCCGTACATGCGTAT
TACGCGCTCGTCGAGGCGCTGCGCGAATTCGACGAAGCGGGCAGCTGGCGCGCGCGTCATGCGCGCTACAAGGCGCTCGC
CGATCAGGCGCAGGCCGGGCTCGCTGCACGCGGGATGCCGCTCGTGCTGCCGGAAGGCGCGTCGTCGGTCGTGCTGCGCG
CGTATCGGCTGCCGCAAGGCGTCACGTACGAAGCGCTGCACGACGGGCTGAAGGCGCGCGGCTTCGTGATCTACGCGGGG
CAAGGCGGGCTGTCGAAGGAACTGTTCCGCATCTCGACGATGGGCGCGATCGAAGCGGCCGACGTCGAGCGGCTGCTGGA
CGGGTTCAGCGAGCTGACGCGGTAA

Upstream 100 bases:

>100_bases
GCCTGCCGCGCCCGACCGTGACGCCGGTCGAGGTCAAGACTCGTCTGATGCGGCACATCGGCGCCGCGCAGACCGAAGCC
CACGCTGAAGGAGCCCATTG

Downstream 100 bases:

>100_bases
GCCGCGCGTCACTTCGTTCGACGAAAGGCCCGTGAGGGCCTTTTTTGTTGGCTGCGGTAAGCCCTGTCGCGGGCAACACG
TCGAACGGTACGAAGTACGG

Product: aminotransferase

Products: NA

Alternate protein names: 2-aminoethylphosphonate aminotransferase; AEP transaminase; AEPT [H]

Number of amino acids: Translated: 354; Mature: 354

Protein sequence:

>354_residues
MLLLNPGPVTLTERVRRSLLQPDLCHRESEFFDLQDEARARLVAAYELDPAEWTAVLMTGSGTAAVESMIAALVPKDGKL
LVIENGVYGERITQIATQYGIAHDVLKHEWMQAPDLAQIAARLDAGGYSHVAVIHHETTTGRLNDLGAIAEVCRARGVKL
LVDGVSSFGAEAIDFAGGDIDAVAATANKCLHGVPGAAFVIVRRSALASAASRTYYLDLGRLAKLQDQRNTPFTPSVHAY
YALVEALREFDEAGSWRARHARYKALADQAQAGLAARGMPLVLPEGASSVVLRAYRLPQGVTYEALHDGLKARGFVIYAG
QGGLSKELFRISTMGAIEAADVERLLDGFSELTR

Sequences:

>Translated_354_residues
MLLLNPGPVTLTERVRRSLLQPDLCHRESEFFDLQDEARARLVAAYELDPAEWTAVLMTGSGTAAVESMIAALVPKDGKL
LVIENGVYGERITQIATQYGIAHDVLKHEWMQAPDLAQIAARLDAGGYSHVAVIHHETTTGRLNDLGAIAEVCRARGVKL
LVDGVSSFGAEAIDFAGGDIDAVAATANKCLHGVPGAAFVIVRRSALASAASRTYYLDLGRLAKLQDQRNTPFTPSVHAY
YALVEALREFDEAGSWRARHARYKALADQAQAGLAARGMPLVLPEGASSVVLRAYRLPQGVTYEALHDGLKARGFVIYAG
QGGLSKELFRISTMGAIEAADVERLLDGFSELTR
>Mature_354_residues
MLLLNPGPVTLTERVRRSLLQPDLCHRESEFFDLQDEARARLVAAYELDPAEWTAVLMTGSGTAAVESMIAALVPKDGKL
LVIENGVYGERITQIATQYGIAHDVLKHEWMQAPDLAQIAARLDAGGYSHVAVIHHETTTGRLNDLGAIAEVCRARGVKL
LVDGVSSFGAEAIDFAGGDIDAVAATANKCLHGVPGAAFVIVRRSALASAASRTYYLDLGRLAKLQDQRNTPFTPSVHAY
YALVEALREFDEAGSWRARHARYKALADQAQAGLAARGMPLVLPEGASSVVLRAYRLPQGVTYEALHDGLKARGFVIYAG
QGGLSKELFRISTMGAIEAADVERLLDGFSELTR

Specific function: Involved in phosphonate degradation [H]

COG id: COG0075

COG function: function code E; Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557289, Length=358, Percent_Identity=25.1396648044693, Blast_Score=82, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17536281, Length=345, Percent_Identity=25.5072463768116, Blast_Score=90, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6321079, Length=364, Percent_Identity=24.4505494505494, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI17530823, Length=355, Percent_Identity=23.3802816901408, Blast_Score=82, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017688
- InterPro:   IPR000192
- InterPro:   IPR012703
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.6.1.37 [H]

Molecular weight: Translated: 38152; Mature: 38152

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLLNPGPVTLTERVRRSLLQPDLCHRESEFFDLQDEARARLVAAYELDPAEWTAVLMTG
CEEECCCCCHHHHHHHHHHCCCHHHCCCCCCCCCCHHHHHEEEEEEECCCCCEEEEEEEC
SGTAAVESMIAALVPKDGKLLVIENGVYGERITQIATQYGIAHDVLKHEWMQAPDLAQIA
CCHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
ARLDAGGYSHVAVIHHETTTGRLNDLGAIAEVCRARGVKLLVDGVSSFGAEAIDFAGGDI
HHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEECHHHCCCHHHHCCCCCH
DAVAATANKCLHGVPGAAFVIVRRSALASAASRTYYLDLGRLAKLQDQRNTPFTPSVHAY
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHCCCCCCCCCHHHH
YALVEALREFDEAGSWRARHARYKALADQAQAGLAARGMPLVLPEGASSVVLRAYRLPQG
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHCCCCEEECCCCHHHHHHHHHCCCC
VTYEALHDGLKARGFVIYAGQGGLSKELFRISTMGAIEAADVERLLDGFSELTR
CCHHHHHCCHHHCCEEEEECCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLLLNPGPVTLTERVRRSLLQPDLCHRESEFFDLQDEARARLVAAYELDPAEWTAVLMTG
CEEECCCCCHHHHHHHHHHCCCHHHCCCCCCCCCCHHHHHEEEEEEECCCCCEEEEEEEC
SGTAAVESMIAALVPKDGKLLVIENGVYGERITQIATQYGIAHDVLKHEWMQAPDLAQIA
CCHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
ARLDAGGYSHVAVIHHETTTGRLNDLGAIAEVCRARGVKLLVDGVSSFGAEAIDFAGGDI
HHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEECHHHCCCHHHHCCCCCH
DAVAATANKCLHGVPGAAFVIVRRSALASAASRTYYLDLGRLAKLQDQRNTPFTPSVHAY
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHCCCCCCCCCHHHH
YALVEALREFDEAGSWRARHARYKALADQAQAGLAARGMPLVLPEGASSVVLRAYRLPQG
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHCCCCEEECCCCHHHHHHHHHCCCC
VTYEALHDGLKARGFVIYAGQGGLSKELFRISTMGAIEAADVERLLDGFSELTR
CCHHHHHCCHHHCCEEEEECCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA