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The map label for this gene is ahpC [H]

Identifier: 189352783

GI number: 189352783

Start: 897371

End: 897934

Strand: Reverse

Name: ahpC [H]

Synonym: BMULJ_04015

Alternate gene names: 189352783

Gene position: 897934-897371 (Counterclockwise)

Preceding gene: 189352784

Following gene: 189352782

Centisome position: 36.31

GC content: 62.23

Gene sequence:

>564_bases
ATGCCGATCATCAACACGCAGATCAAACCGTTCAAGGCCACCGCATACCACAACGGCGAATTCGTGCCCGTGTCCGACGA
GAACTTCAAGGGCAAGTGGTCCGTCGTCGTGTTCTACCCGGCCGACTTCACGTTCGTGTGCCCGACCGAACTCGGCGATC
TCGCCGACCGCTACGCGGAATTCCAGAAGCTCGGCGTCGAGATCTACGCGGTGTCGACCGACACGCACTTCACGCACAAG
GCATGGCACGACACGTCGGACACGATCGGCAAGATCAAGTACCCGATGATCGGCGATCCGACGCTGACGCTGTCGCGCAA
CTTCGACGTGCTGATCGAGGAAGAAGGGATGGCGCTGCGCGGCACGTTCGTGATCAACCCGGAAGGCGAGATCAAGCTCT
GCGAGATCCACGACAACGGCATCGGCCGCGACGCAGGCGAACTGCTGCGCAAGGTGCAGGCCGCGCAATACATCGCCGCG
CATCCGGGTGAAGTCTGCCCGGCCAAGTGGACGCCGGGTGCGGAAACGCTGACCCCGTCGCTCGACCTGATCGGCAAGAT
CTGA

Upstream 100 bases:

>100_bases
TTCCCGATGCCGCGGATTAAAACAAGCAATTTCACAGACTGCGGGTGAACCCGGATACTGGCGTCTCTCCATTCATCACC
GACGCAAAGGGAAACACCAG

Downstream 100 bases:

>100_bases
CGATCGCCCCGCGCGCCGCACAGGCGCGCGACGGCGGGCCGCCGCATCGCGCGGCCCGCATCCCCTTCTCCGGCATGCAG
TGCCCGGCCGGAACCTTCGC

Product: alkyl hydroperoxide reductase subunit C

Products: NA

Alternate protein names: Alkyl hydroperoxide reductase protein C22; Peroxiredoxin; SCRP-23; Sulfate starvation-induced protein 8; SSI8; Thioredoxin peroxidase [H]

Number of amino acids: Translated: 187; Mature: 186

Protein sequence:

>187_residues
MPIINTQIKPFKATAYHNGEFVPVSDENFKGKWSVVVFYPADFTFVCPTELGDLADRYAEFQKLGVEIYAVSTDTHFTHK
AWHDTSDTIGKIKYPMIGDPTLTLSRNFDVLIEEEGMALRGTFVINPEGEIKLCEIHDNGIGRDAGELLRKVQAAQYIAA
HPGEVCPAKWTPGAETLTPSLDLIGKI

Sequences:

>Translated_187_residues
MPIINTQIKPFKATAYHNGEFVPVSDENFKGKWSVVVFYPADFTFVCPTELGDLADRYAEFQKLGVEIYAVSTDTHFTHK
AWHDTSDTIGKIKYPMIGDPTLTLSRNFDVLIEEEGMALRGTFVINPEGEIKLCEIHDNGIGRDAGELLRKVQAAQYIAA
HPGEVCPAKWTPGAETLTPSLDLIGKI
>Mature_186_residues
PIINTQIKPFKATAYHNGEFVPVSDENFKGKWSVVVFYPADFTFVCPTELGDLADRYAEFQKLGVEIYAVSTDTHFTHKA
WHDTSDTIGKIKYPMIGDPTLTLSRNFDVLIEEEGMALRGTFVINPEGEIKLCEIHDNGIGRDAGELLRKVQAAQYIAAH
PGEVCPAKWTPGAETLTPSLDLIGKI

Specific function: Directly reduces organic hydroperoxides in its reduced dithiol form [H]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI5802974, Length=182, Percent_Identity=45.6043956043956, Blast_Score=167, Evalue=4e-42,
Organism=Homo sapiens, GI32483377, Length=179, Percent_Identity=46.3687150837989, Blast_Score=167, Evalue=5e-42,
Organism=Homo sapiens, GI32189392, Length=175, Percent_Identity=45.1428571428571, Blast_Score=158, Evalue=2e-39,
Organism=Homo sapiens, GI4505591, Length=175, Percent_Identity=42.2857142857143, Blast_Score=153, Evalue=9e-38,
Organism=Homo sapiens, GI32455266, Length=175, Percent_Identity=42.2857142857143, Blast_Score=153, Evalue=9e-38,
Organism=Homo sapiens, GI32455264, Length=175, Percent_Identity=42.2857142857143, Blast_Score=153, Evalue=9e-38,
Organism=Homo sapiens, GI5453549, Length=180, Percent_Identity=42.2222222222222, Blast_Score=147, Evalue=4e-36,
Organism=Homo sapiens, GI33188454, Length=74, Percent_Identity=51.3513513513513, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI4758638, Length=157, Percent_Identity=30.5732484076433, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1786822, Length=187, Percent_Identity=66.3101604278075, Blast_Score=277, Evalue=3e-76,
Organism=Caenorhabditis elegans, GI193204376, Length=174, Percent_Identity=44.2528735632184, Blast_Score=158, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI32565831, Length=174, Percent_Identity=44.2528735632184, Blast_Score=158, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI17554494, Length=177, Percent_Identity=41.2429378531073, Blast_Score=149, Evalue=6e-37,
Organism=Caenorhabditis elegans, GI25153706, Length=169, Percent_Identity=28.4023668639053, Blast_Score=69, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6320661, Length=181, Percent_Identity=39.7790055248619, Blast_Score=143, Evalue=2e-35,
Organism=Saccharomyces cerevisiae, GI6323613, Length=182, Percent_Identity=40.1098901098901, Blast_Score=140, Evalue=1e-34,
Organism=Saccharomyces cerevisiae, GI6319407, Length=159, Percent_Identity=30.8176100628931, Blast_Score=84, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24656348, Length=181, Percent_Identity=43.646408839779, Blast_Score=159, Evalue=1e-39,
Organism=Drosophila melanogaster, GI17864676, Length=181, Percent_Identity=43.646408839779, Blast_Score=159, Evalue=1e-39,
Organism=Drosophila melanogaster, GI17738015, Length=177, Percent_Identity=40.6779661016949, Blast_Score=157, Evalue=4e-39,
Organism=Drosophila melanogaster, GI21357347, Length=182, Percent_Identity=40.6593406593407, Blast_Score=154, Evalue=3e-38,
Organism=Drosophila melanogaster, GI17157991, Length=180, Percent_Identity=40, Blast_Score=147, Evalue=5e-36,
Organism=Drosophila melanogaster, GI24641739, Length=180, Percent_Identity=40, Blast_Score=147, Evalue=5e-36,
Organism=Drosophila melanogaster, GI17975518, Length=167, Percent_Identity=32.3353293413174, Blast_Score=91, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24652434, Length=167, Percent_Identity=32.3353293413174, Blast_Score=91, Evalue=5e-19,
Organism=Drosophila melanogaster, GI24652436, Length=167, Percent_Identity=32.3353293413174, Blast_Score=91, Evalue=5e-19,
Organism=Drosophila melanogaster, GI24581278, Length=158, Percent_Identity=32.9113924050633, Blast_Score=87, Evalue=8e-18,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR017559
- InterPro:   IPR019479
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 20743; Mature: 20612

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIINTQIKPFKATAYHNGEFVPVSDENFKGKWSVVVFYPADFTFVCPTELGDLADRYAE
CCCCCCCCCCEEEEEEECCCEEECCCCCCCCEEEEEEEECCCEEEECCCHHHHHHHHHHH
FQKLGVEIYAVSTDTHFTHKAWHDTSDTIGKIKYPMIGDPTLTLSRNFDVLIEEEGMALR
HHHCCEEEEEEECCCCEEECCCCCCCCCCCEEECCCCCCCEEEEECCCEEEEECCCCEEE
GTFVINPEGEIKLCEIHDNGIGRDAGELLRKVQAAQYIAAHPGEVCPAKWTPGAETLTPS
EEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
LDLIGKI
HHHEECC
>Mature Secondary Structure 
PIINTQIKPFKATAYHNGEFVPVSDENFKGKWSVVVFYPADFTFVCPTELGDLADRYAE
CCCCCCCCCEEEEEEECCCEEECCCCCCCCEEEEEEEECCCEEEECCCHHHHHHHHHHH
FQKLGVEIYAVSTDTHFTHKAWHDTSDTIGKIKYPMIGDPTLTLSRNFDVLIEEEGMALR
HHHCCEEEEEEECCCCEEECCCCCCCCCCCEEECCCCCCCEEEEECCCEEEEECCCCEEE
GTFVINPEGEIKLCEIHDNGIGRDAGELLRKVQAAQYIAAHPGEVCPAKWTPGAETLTPS
EEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
LDLIGKI
HHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]