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The map label for this gene is betA [C]

Identifier: 189352750

GI number: 189352750

Start: 857523

End: 859175

Strand: Direct

Name: betA [C]

Synonym: BMULJ_03982

Alternate gene names: 189352750

Gene position: 857523-859175 (Clockwise)

Preceding gene: 189352748

Following gene: 189352751

Centisome position: 34.67

GC content: 68.72

Gene sequence:

>1653_bases
ATGACACGCAGCTTCGACTATGTCGTGGTCGGCGCGGGATCGGCCGGTTGCGTCCTCGCCCATCGCTTGTCCGAGGGCGG
CCGCCATACGGTCTGCCTGCTCGAGGCGGGCCCCGCGGACAACTACATGTGGATCCACGTGCCGATCGGTTACGGCAAGA
CGATGTTCCATCCCGTCTACAACTGGGGCTTTCATACCGATCCCGATCCGAACATGCACAACCGGCGGCTGTACTGGCCG
CGCGGGCGCACGCTCGGCGGCTGCAGCTCGATCAACGGGCTGATCTACGTGCGCGGCCAGCAGCAGGACTATGACCATTG
GGCCGCGCTCGGCAATCGCGGCTGGAGCTGGCGCGACTGCCTGCCGTACTTTCGGCGGCTCGAACACAACACGCTCGGCG
AAGGGCCGACGCGCGGCATCGGCGGCCCGCTGTGGGCGTCGACGATCCGCCAGCGTCACGAACTCGTCGACGCATTCATT
GCCGCGTCGAACCGGCTCGGCGTGCGCAGCGTCGACGACTTCAACACCGGCGATCAGGAAGGCGTCGGCTACTACCAGCT
GACGACACGCAACGGGCTGCGCTGCTCGACCGCGGTCGCGTATCTGAAGCCCGCGCGCGGGCGGCTGAACCTGCACGTCG
AAACCGATGCGCAGGCGCTGAAGGTGCTGTTCGACGGCACGCAGGCACGCGGCGTGCGCTACGTGCGCCACGGCGAGACG
CACGACGTGCACGCGCGGCGCGAGGTCGTGCTCGCGGCCGGCGCGCTGCAGTCGCCGCAATTGCTGCAGGTGTCGGGCGT
CGGGCCCGCCGCGCTGCTGAGCCGGCTCGGGATACCGATCGTCGCCGATCGCGCGGGCGTCGGCGAGAACCTGCAGGATC
ATCTGCAGATTCGTCTGATCTACGAGGTCACGAAGCCGATCACGACGAACGACGCGCTGCATTCGTGGTTCGGCCGCGCG
AAGATGGGTCTGCAATGGGCGCTGATGCGCGGCGGGCCGCTCGCGGTCGGCATCAATCAGGGCGGCATGTTCTGTCGCGC
GCTGCCCGAAGCGGCGACGCCCGACATTCAGTTTCATTTCTCGACGCTGTCCGCCGATTCGGCGGGCGGCAGCGTGCATC
CGTTTCCCGGCTGCACGTATTCCGTGTGCCAGCTGCGGCCCGAATCGCGCGGCACCGTGCGCATCCGCACCGACGATGCG
CGCGATGCGCCGTCGATCCAGCCGAACTATCTCGACACCGAGCTCGACCGCCGCACGACGGTGGCCGGCGTGCGCTTCGC
ACGGCGCGTCGCGGCGACCGAGCCGATGGCGTCGCTGATGAAGCGCGAGGTGCGGCCCGGCGCCGATGCGCAGACCGACG
ACGAACTGCTCGAGTTCTGCCGCGAATACGGGCAGACGATCTTTCATCCGTCCGGCACCGCGAAGATGGGTGTCGCGAGC
GATCCGCTCGCGGTCGTCGACGAGCGGCTGCGCGTCTACGGCACGCGCGGGCTGCGCGTGGTCGACTGCTCGATCATGCC
GACGCTCGTGTCGGGCAACACCAACGTGCCGATCGTGATGGTCGCGGAGAAAGCGTCCGACATGATCCTCGAGGACGCAC
GCGAGGCCGACCGTGGCCGCAGCGTCGCGCCGGCCGTCGAAGCCGCCGCCTAG

Upstream 100 bases:

>100_bases
ATTCCCCGCGTGGACAATAAATCGGCTTGAACGTGTTCCGTGCGCTCAATAAATTTGGACAAAACATACCGAATTTTTCA
TATCGGAACGGAGACACGGA

Downstream 100 bases:

>100_bases
CGCGACACGCCGAATCGCCCGCGCGGCCCGTGCTCCTGCGCCCGGACGGCCGCCGCGCGCTCATCGGATGCCCCCGCCGG
TACGGCGTCGGGGCAGGTCG

Product: choline dehydrogenase

Products: NA

Alternate protein names: SDH [H]

Number of amino acids: Translated: 550; Mature: 549

Protein sequence:

>550_residues
MTRSFDYVVVGAGSAGCVLAHRLSEGGRHTVCLLEAGPADNYMWIHVPIGYGKTMFHPVYNWGFHTDPDPNMHNRRLYWP
RGRTLGGCSSINGLIYVRGQQQDYDHWAALGNRGWSWRDCLPYFRRLEHNTLGEGPTRGIGGPLWASTIRQRHELVDAFI
AASNRLGVRSVDDFNTGDQEGVGYYQLTTRNGLRCSTAVAYLKPARGRLNLHVETDAQALKVLFDGTQARGVRYVRHGET
HDVHARREVVLAAGALQSPQLLQVSGVGPAALLSRLGIPIVADRAGVGENLQDHLQIRLIYEVTKPITTNDALHSWFGRA
KMGLQWALMRGGPLAVGINQGGMFCRALPEAATPDIQFHFSTLSADSAGGSVHPFPGCTYSVCQLRPESRGTVRIRTDDA
RDAPSIQPNYLDTELDRRTTVAGVRFARRVAATEPMASLMKREVRPGADAQTDDELLEFCREYGQTIFHPSGTAKMGVAS
DPLAVVDERLRVYGTRGLRVVDCSIMPTLVSGNTNVPIVMVAEKASDMILEDAREADRGRSVAPAVEAAA

Sequences:

>Translated_550_residues
MTRSFDYVVVGAGSAGCVLAHRLSEGGRHTVCLLEAGPADNYMWIHVPIGYGKTMFHPVYNWGFHTDPDPNMHNRRLYWP
RGRTLGGCSSINGLIYVRGQQQDYDHWAALGNRGWSWRDCLPYFRRLEHNTLGEGPTRGIGGPLWASTIRQRHELVDAFI
AASNRLGVRSVDDFNTGDQEGVGYYQLTTRNGLRCSTAVAYLKPARGRLNLHVETDAQALKVLFDGTQARGVRYVRHGET
HDVHARREVVLAAGALQSPQLLQVSGVGPAALLSRLGIPIVADRAGVGENLQDHLQIRLIYEVTKPITTNDALHSWFGRA
KMGLQWALMRGGPLAVGINQGGMFCRALPEAATPDIQFHFSTLSADSAGGSVHPFPGCTYSVCQLRPESRGTVRIRTDDA
RDAPSIQPNYLDTELDRRTTVAGVRFARRVAATEPMASLMKREVRPGADAQTDDELLEFCREYGQTIFHPSGTAKMGVAS
DPLAVVDERLRVYGTRGLRVVDCSIMPTLVSGNTNVPIVMVAEKASDMILEDAREADRGRSVAPAVEAAA
>Mature_549_residues
TRSFDYVVVGAGSAGCVLAHRLSEGGRHTVCLLEAGPADNYMWIHVPIGYGKTMFHPVYNWGFHTDPDPNMHNRRLYWPR
GRTLGGCSSINGLIYVRGQQQDYDHWAALGNRGWSWRDCLPYFRRLEHNTLGEGPTRGIGGPLWASTIRQRHELVDAFIA
ASNRLGVRSVDDFNTGDQEGVGYYQLTTRNGLRCSTAVAYLKPARGRLNLHVETDAQALKVLFDGTQARGVRYVRHGETH
DVHARREVVLAAGALQSPQLLQVSGVGPAALLSRLGIPIVADRAGVGENLQDHLQIRLIYEVTKPITTNDALHSWFGRAK
MGLQWALMRGGPLAVGINQGGMFCRALPEAATPDIQFHFSTLSADSAGGSVHPFPGCTYSVCQLRPESRGTVRIRTDDAR
DAPSIQPNYLDTELDRRTTVAGVRFARRVAATEPMASLMKREVRPGADAQTDDELLEFCREYGQTIFHPSGTAKMGVASD
PLAVVDERLRVYGTRGLRVVDCSIMPTLVSGNTNVPIVMVAEKASDMILEDAREADRGRSVAPAVEAAA

Specific function: Can Catalyze The Oxidation Of Choline To Betaine Aldehyde And Betaine Aldehyde To Glycine Betaine At The Same Rate. [C]

COG id: COG2303

COG function: function code E; Choline dehydrogenase and related flavoproteins

Gene ontology:

Cell location: Membrane-Bound [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GMC oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI217272839, Length=532, Percent_Identity=43.421052631579, Blast_Score=424, Evalue=1e-118,
Organism=Escherichia coli, GI1786503, Length=534, Percent_Identity=41.0112359550562, Blast_Score=373, Evalue=1e-104,
Organism=Caenorhabditis elegans, GI17532301, Length=546, Percent_Identity=39.1941391941392, Blast_Score=380, Evalue=1e-106,
Organism=Drosophila melanogaster, GI24642042, Length=589, Percent_Identity=39.7283531409168, Blast_Score=364, Evalue=1e-101,
Organism=Drosophila melanogaster, GI24642059, Length=566, Percent_Identity=38.6925795053004, Blast_Score=347, Evalue=2e-95,
Organism=Drosophila melanogaster, GI45549471, Length=571, Percent_Identity=37.6532399299475, Blast_Score=333, Evalue=2e-91,
Organism=Drosophila melanogaster, GI45551458, Length=569, Percent_Identity=37.7855887521968, Blast_Score=332, Evalue=4e-91,
Organism=Drosophila melanogaster, GI24642055, Length=592, Percent_Identity=36.8243243243243, Blast_Score=327, Evalue=1e-89,
Organism=Drosophila melanogaster, GI24642048, Length=566, Percent_Identity=36.7491166077738, Blast_Score=319, Evalue=3e-87,
Organism=Drosophila melanogaster, GI18859995, Length=573, Percent_Identity=36.9982547993019, Blast_Score=308, Evalue=7e-84,
Organism=Drosophila melanogaster, GI24650267, Length=569, Percent_Identity=34.7978910369069, Blast_Score=300, Evalue=2e-81,
Organism=Drosophila melanogaster, GI24642039, Length=580, Percent_Identity=35.5172413793103, Blast_Score=298, Evalue=7e-81,
Organism=Drosophila melanogaster, GI17137792, Length=556, Percent_Identity=35.431654676259, Blast_Score=290, Evalue=2e-78,
Organism=Drosophila melanogaster, GI24642051, Length=572, Percent_Identity=33.2167832167832, Blast_Score=277, Evalue=1e-74,
Organism=Drosophila melanogaster, GI24642037, Length=570, Percent_Identity=33.859649122807, Blast_Score=267, Evalue=2e-71,
Organism=Drosophila melanogaster, GI18859993, Length=568, Percent_Identity=32.7464788732394, Blast_Score=265, Evalue=5e-71,
Organism=Drosophila melanogaster, GI24642035, Length=302, Percent_Identity=41.0596026490066, Blast_Score=211, Evalue=1e-54,
Organism=Drosophila melanogaster, GI24642057, Length=587, Percent_Identity=31.175468483816, Blast_Score=174, Evalue=2e-43,
Organism=Drosophila melanogaster, GI24645930, Length=586, Percent_Identity=28.3276450511945, Blast_Score=154, Evalue=1e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012132
- InterPro:   IPR000172
- InterPro:   IPR007867 [H]

Pfam domain/function: PF05199 GMC_oxred_C; PF00732 GMC_oxred_N [H]

EC number: =1.1.99.32 [H]

Molecular weight: Translated: 60279; Mature: 60148

Theoretical pI: Translated: 8.13; Mature: 8.13

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00624 GMC_OXRED_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRSFDYVVVGAGSAGCVLAHRLSEGGRHTVCLLEAGPADNYMWIHVPIGYGKTMFHPVY
CCCCCCEEEEECCCCCHHHHHHHCCCCCEEEEEEECCCCCCEEEEEEECCCCCHHHHHHH
NWGFHTDPDPNMHNRRLYWPRGRTLGGCSSINGLIYVRGQQQDYDHWAALGNRGWSWRDC
CCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHCCCCCCHHHH
LPYFRRLEHNTLGEGPTRGIGGPLWASTIRQRHELVDAFIAASNRLGVRSVDDFNTGDQE
HHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
GVGYYQLTTRNGLRCSTAVAYLKPARGRLNLHVETDAQALKVLFDGTQARGVRYVRHGET
CCCEEEEECCCCCCHHHHHHEECCCCCEEEEEEECCHHHHHHHHCCCHHCCEEEEECCCC
HDVHARREVVLAAGALQSPQLLQVSGVGPAALLSRLGIPIVADRAGVGENLQDHLQIRLI
CCCHHHHEEEEEECCCCCCCEEEECCCCHHHHHHHCCCCEEECCCCCCCCCHHCEEEEEE
YEVTKPITTNDALHSWFGRAKMGLQWALMRGGPLAVGINQGGMFCRALPEAATPDIQFHF
EEECCCCCCCHHHHHHHHHHHCCEEEEEECCCEEEEEECCCCEEEEECCCCCCCCEEEEE
STLSADSAGGSVHPFPGCTYSVCQLRPESRGTVRIRTDDARDAPSIQPNYLDTELDRRTT
EEECCCCCCCCCCCCCCCCCCEEECCCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHH
VAGVRFARRVAATEPMASLMKREVRPGADAQTDDELLEFCREYGQTIFHPSGTAKMGVAS
HHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCEEECCCCCCCCCCCC
DPLAVVDERLRVYGTRGLRVVDCSIMPTLVSGNTNVPIVMVAEKASDMILEDAREADRGR
CCHHHHHHHHHHEECCCCEEEEEEEEEEEECCCCCCCEEEEECCCHHHHHHHHHHHHCCC
SVAPAVEAAA
CCCCHHHCCC
>Mature Secondary Structure 
TRSFDYVVVGAGSAGCVLAHRLSEGGRHTVCLLEAGPADNYMWIHVPIGYGKTMFHPVY
CCCCCEEEEECCCCCHHHHHHHCCCCCEEEEEEECCCCCCEEEEEEECCCCCHHHHHHH
NWGFHTDPDPNMHNRRLYWPRGRTLGGCSSINGLIYVRGQQQDYDHWAALGNRGWSWRDC
CCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHCCCCCCHHHH
LPYFRRLEHNTLGEGPTRGIGGPLWASTIRQRHELVDAFIAASNRLGVRSVDDFNTGDQE
HHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
GVGYYQLTTRNGLRCSTAVAYLKPARGRLNLHVETDAQALKVLFDGTQARGVRYVRHGET
CCCEEEEECCCCCCHHHHHHEECCCCCEEEEEEECCHHHHHHHHCCCHHCCEEEEECCCC
HDVHARREVVLAAGALQSPQLLQVSGVGPAALLSRLGIPIVADRAGVGENLQDHLQIRLI
CCCHHHHEEEEEECCCCCCCEEEECCCCHHHHHHHCCCCEEECCCCCCCCCHHCEEEEEE
YEVTKPITTNDALHSWFGRAKMGLQWALMRGGPLAVGINQGGMFCRALPEAATPDIQFHF
EEECCCCCCCHHHHHHHHHHHCCEEEEEECCCEEEEEECCCCEEEEECCCCCCCCEEEEE
STLSADSAGGSVHPFPGCTYSVCQLRPESRGTVRIRTDDARDAPSIQPNYLDTELDRRTT
EEECCCCCCCCCCCCCCCCCCEEECCCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHH
VAGVRFARRVAATEPMASLMKREVRPGADAQTDDELLEFCREYGQTIFHPSGTAKMGVAS
HHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCEEECCCCCCCCCCCC
DPLAVVDERLRVYGTRGLRVVDCSIMPTLVSGNTNVPIVMVAEKASDMILEDAREADRGR
CCHHHHHHHHHHEECCCCEEEEEEEEEEEECCCCCCCEEEEECCCHHHHHHHHHHHHCCC
SVAPAVEAAA
CCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9023923 [H]