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The map label for this gene is asd [H]

Identifier: 189352654

GI number: 189352654

Start: 742123

End: 743244

Strand: Direct

Name: asd [H]

Synonym: BMULJ_03885

Alternate gene names: 189352654

Gene position: 742123-743244 (Clockwise)

Preceding gene: 189352653

Following gene: 189352655

Centisome position: 30.01

GC content: 64.62

Gene sequence:

>1122_bases
ATGAACGTAGGTCTCGTAGGTTGGCGCGGCATGGTCGGCAGCGTCCTGATGCAGCGCATGCAGGAAGAGGGCGATTTCGA
CCTGATCGAACCGGTGTTTTTCAGCACCAGCAACTCGGGCGGCAAGGCACCGTCGTTCGCGAAAAACGAGACCACGCTGA
AGGACGCGACCAACGTCGACGAACTGAAGAAGTGCGACGTCATCATCACGTGCCAGGGCGGCGACTACACGAATGACGTG
TTCCCGAAGCTGCGCGCGGCGGGCTGGAACGGCTACTGGATCGATGCGGCGTCGTCGCTGCGGATGAAGGACGACGCGGT
CATCATCCTCGATCCGGTGAACCTCGACGTCATCAAGGACGCGCTCGTCAAGGGCACGAAGAACTTCATCGGCGGCAACT
GCACGGTCAGCCTGATGCTGATGGCGCTCGGCGGCCTGTTCCGCGAGAACCTCGTCGATTGGATGACGGCCATGACGTAT
CAGGCCGCGTCGGGCGCGGGCGCGCAGAACATGCGTGAACTGCTGTCGCAGATGGGCGCGCTGCACGGCGCGGTGCAGCA
GCAGCTCGCCGATCCGGCATCGGCGATCCTCGACATCGATCGCCGCGTGCTCGCCACGATGAACAGCGACGCGATGCCGA
CGAGCCACTTCGGCGTGCCGCTCGCGGGTTCGCTGATTCCGTGGATCGACAAGGATCTCGGCAACGGCATGTCGAAGGAA
GAATGGAAGGGCGGCGCGGAAACGAACAAGATCCTCGGCAAGCCGGCGATGGGCGAGCCGGGCTCGATTCCGGTCGACGG
GCTGTGCGTGCGGATCGGCGCGATGCGCTGCCACTCGCAGGCGCTGACGATCAAGCTGAAGAAGGACGTGCCGCTCGACG
AGATCAACGGCATTCTCGCGTCGGCGAACGACTGGGTGAAGGTCGTGCCGAACGAGCGCGAAGCGTCGATGCACGATCTG
TCGCCGGCGAAGGTCACCGGCACGCTGACCGTGCCGGTCGGCCGTCTGCGCAAGCTCGCGATGGGCGGCGAATACCTGTC
GGCGTTCACGGTCGGCGATCAGTTGCTGTGGGGCGCGGCCGAACCGCTGCGCCGCATGCTGCGCATCCTGCTCGACAAGT
AA

Upstream 100 bases:

>100_bases
ACGATCATTAAACGCTGATCGTCCGTCGTGCCCGCCTGTTTCCCCGCGCGGTCACGCCGGGGGCGGAAATGGCGGGGAAG
CTCCATTCAAAGGGTTAGTC

Downstream 100 bases:

>100_bases
GACGAGATCGTGCGCCGGCCGGCGCGCGATGCGACGCGCCTGCGTGCCTTCAACGGGCCGCAGGCGCGTTTTTTATCGGC
GGGCGCCGTGCCCGAAAATG

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 373; Mature: 373

Protein sequence:

>373_residues
MNVGLVGWRGMVGSVLMQRMQEEGDFDLIEPVFFSTSNSGGKAPSFAKNETTLKDATNVDELKKCDVIITCQGGDYTNDV
FPKLRAAGWNGYWIDAASSLRMKDDAVIILDPVNLDVIKDALVKGTKNFIGGNCTVSLMLMALGGLFRENLVDWMTAMTY
QAASGAGAQNMRELLSQMGALHGAVQQQLADPASAILDIDRRVLATMNSDAMPTSHFGVPLAGSLIPWIDKDLGNGMSKE
EWKGGAETNKILGKPAMGEPGSIPVDGLCVRIGAMRCHSQALTIKLKKDVPLDEINGILASANDWVKVVPNEREASMHDL
SPAKVTGTLTVPVGRLRKLAMGGEYLSAFTVGDQLLWGAAEPLRRMLRILLDK

Sequences:

>Translated_373_residues
MNVGLVGWRGMVGSVLMQRMQEEGDFDLIEPVFFSTSNSGGKAPSFAKNETTLKDATNVDELKKCDVIITCQGGDYTNDV
FPKLRAAGWNGYWIDAASSLRMKDDAVIILDPVNLDVIKDALVKGTKNFIGGNCTVSLMLMALGGLFRENLVDWMTAMTY
QAASGAGAQNMRELLSQMGALHGAVQQQLADPASAILDIDRRVLATMNSDAMPTSHFGVPLAGSLIPWIDKDLGNGMSKE
EWKGGAETNKILGKPAMGEPGSIPVDGLCVRIGAMRCHSQALTIKLKKDVPLDEINGILASANDWVKVVPNEREASMHDL
SPAKVTGTLTVPVGRLRKLAMGGEYLSAFTVGDQLLWGAAEPLRRMLRILLDK
>Mature_373_residues
MNVGLVGWRGMVGSVLMQRMQEEGDFDLIEPVFFSTSNSGGKAPSFAKNETTLKDATNVDELKKCDVIITCQGGDYTNDV
FPKLRAAGWNGYWIDAASSLRMKDDAVIILDPVNLDVIKDALVKGTKNFIGGNCTVSLMLMALGGLFRENLVDWMTAMTY
QAASGAGAQNMRELLSQMGALHGAVQQQLADPASAILDIDRRVLATMNSDAMPTSHFGVPLAGSLIPWIDKDLGNGMSKE
EWKGGAETNKILGKPAMGEPGSIPVDGLCVRIGAMRCHSQALTIKLKKDVPLDEINGILASANDWVKVVPNEREASMHDL
SPAKVTGTLTVPVGRLRKLAMGGEYLSAFTVGDQLLWGAAEPLRRMLRILLDK

Specific function: Second step in the common biosynthetic pathway leading from Asp to the cell wall precursor meso-diaminopimelate, to Lys, to Met, to Ile and to Thr. [C]

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1789841, Length=369, Percent_Identity=68.5636856368564, Blast_Score=526, Evalue=1e-150,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000319
- InterPro:   IPR011534
- InterPro:   IPR012080
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 40208; Mature: 40208

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: PS01103 ASD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVGLVGWRGMVGSVLMQRMQEEGDFDLIEPVFFSTSNSGGKAPSFAKNETTLKDATNVD
CCCCCCCHHHHHHHHHHHHHHHCCCCCEECHHEEECCCCCCCCCCCCCCCCCHHCCCCHH
ELKKCDVIITCQGGDYTNDVFPKLRAAGWNGYWIDAASSLRMKDDAVIILDPVNLDVIKD
HHHHCCEEEEECCCCCCHHHHHHHHHCCCCCEEEECCCCCEECCCCEEEEECCCHHHHHH
ALVKGTKNFIGGNCTVSLMLMALGGLFRENLVDWMTAMTYQAASGAGAQNMRELLSQMGA
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
LHGAVQQQLADPASAILDIDRRVLATMNSDAMPTSHFGVPLAGSLIPWIDKDLGNGMSKE
HHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCHH
EWKGGAETNKILGKPAMGEPGSIPVDGLCVRIGAMRCHSQALTIKLKKDVPLDEINGILA
HHCCCCCHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEEECCCCHHHHCCHHC
SANDWVKVVPNEREASMHDLSPAKVTGTLTVPVGRLRKLAMGGEYLSAFTVGDQLLWGAA
CCCCCEEECCCCCCCHHHCCCCCEEEEEEECCHHHHHHHHCCCHHHHHHHHHHHHHHCCH
EPLRRMLRILLDK
HHHHHHHHHHHCC
>Mature Secondary Structure
MNVGLVGWRGMVGSVLMQRMQEEGDFDLIEPVFFSTSNSGGKAPSFAKNETTLKDATNVD
CCCCCCCHHHHHHHHHHHHHHHCCCCCEECHHEEECCCCCCCCCCCCCCCCCHHCCCCHH
ELKKCDVIITCQGGDYTNDVFPKLRAAGWNGYWIDAASSLRMKDDAVIILDPVNLDVIKD
HHHHCCEEEEECCCCCCHHHHHHHHHCCCCCEEEECCCCCEECCCCEEEEECCCHHHHHH
ALVKGTKNFIGGNCTVSLMLMALGGLFRENLVDWMTAMTYQAASGAGAQNMRELLSQMGA
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
LHGAVQQQLADPASAILDIDRRVLATMNSDAMPTSHFGVPLAGSLIPWIDKDLGNGMSKE
HHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCHH
EWKGGAETNKILGKPAMGEPGSIPVDGLCVRIGAMRCHSQALTIKLKKDVPLDEINGILA
HHCCCCCHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEEECCCCHHHHCCHHC
SANDWVKVVPNEREASMHDLSPAKVTGTLTVPVGRLRKLAMGGEYLSAFTVGDQLLWGAA
CCCCCEEECCCCCCCHHHCCCCCEEEEEEECCHHHHHHHHCCCHHHHHHHHHHHHHHCCH
EPLRRMLRILLDK
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9084174; 10984043 [H]