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The map label for this gene is ndh [H]

Identifier: 189352471

GI number: 189352471

Start: 520642

End: 521976

Strand: Direct

Name: ndh [H]

Synonym: BMULJ_03690

Alternate gene names: 189352471

Gene position: 520642-521976 (Clockwise)

Preceding gene: 189352470

Following gene: 189352472

Centisome position: 21.05

GC content: 69.59

Gene sequence:

>1335_bases
ATGCATCGGATCATCATCGTAGGCGGCGGCGCGGGCGGCCTGGAACTGGCGACGCGGCTCGGCGACCGCTACGGCGCGCG
CGGCAATCGTCCGGCACGCGCACTCGTCACACTCGTCGACCGCAATCCGACCCACATCTGGAAACCGCTGCTGCACGAAG
TCGCGGCCGGCAGCATGGACCCGTTCACACAGGAACTCGAATATGCGGCGCAGGCGCGCTGGCATGGCTTCGAGTTTCAG
CAGGGCGAGCTCGCCGGGCTCGACCGTGCCGCGAAGCGCATCACGCTGTCGCCCGTCAACGACAGCGACGGCGCCGAGCT
GCTGCCCGCGCGCGAACTCGAATATGACACGCTCGTGATCGCGATCGGCAGCACGACGCACTTCTTCGGCGTGCAGGGCG
CCCCGGAAAACGCGATCGCGCTCGATACCGTCGGCGAGGCCGAACGCTTCCGCAAGCGGCTGATCGCCGCGTGCATGCGT
GCCGAGCATCAGGCGCCGGCAGCCGTTGCACCCGGCGAGCCGGCCGAGCCGCGTATCCAGGTCGTGATCGTCGGCGGCGG
TGCGACGGGCGTCGAGCTGTCCGCCGAGCTGCGCAACACCGCGCAGGTGCTGTCGGTGTACGGGCTGCACAAGCTCGATC
CGCGCCACGACGTCGGCATCGTGCTGATCGAATCGGGGCCGCGCATTCTGCCGGCGCTGCCGGAGCGCGTGTCGTCCGCG
ACCGCCGAACTGCTCGAGAAGCTCGGCGTGCGGCTGATGCTCGGCGAGCGCGTGACCGAAGTCGCGCCCGGCGCCGTGCA
TACGGCGAGCGGCAAGGCCGTGCGCGCCGACCTCACGGTCTGGGCGGCCGGCATCAAGGCGCCGGCCGTGCTCGCGCATC
TCGACGGCCTTCAAGTCAACAAGCTCGGTCAGCTCGACGTGCGCCGCACGCTGCAGACGGTCACCGACGACAACGTCTTC
GCGCTCGGCGATTGCGCGGCATGCGCGTGGCCCGGCAGCGAACGCAACGTGCCGCCGCGCGCGCAGGCCGCGCACCAGCA
GGCGAGCTTTCTGCTGAAGGCGATCGCGTGCCGGCTCGACGGGCGTCCGCTTCCCGAGTTCACGTATCGCGACTTCGGGT
CGCTCGTCTCGCTCGGTCACTTCAGCGCGGTCGGCAACCTGATGGGCGGCCTGATCGGCGGCAACATGCTGATCGAAGGC
CTGTTCGCGCGCTTCATGTACATGTCGCTGTACCGGCTGCACATCGCGGCGCTGCACGGCTATCCGCGGATGATCCTCGA
TACGGTCGCGCACTGGCTGCGTCGCACGACGCTGCCGCGCGTGAAGCTGCACTGA

Upstream 100 bases:

>100_bases
CATCGATGATGTCCGAACCGGTTAATCGACGCGACGGTGCGCGGATGAAGCCCGCATCGTCCGGCGGCAACAGGTTTCGA
ATCGCAAAGGGGGGAATCAG

Downstream 100 bases:

>100_bases
ACGCGTTCGGCACGCGCGGCACGTCGGTCGACGCACCGGCGGCCGCCGTCTGTCATCGAGTCTTACATATCGGACAGTTG
ACGCGACAACGGATTATTGG

Product: NADH dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 444; Mature: 444

Protein sequence:

>444_residues
MHRIIIVGGGAGGLELATRLGDRYGARGNRPARALVTLVDRNPTHIWKPLLHEVAAGSMDPFTQELEYAAQARWHGFEFQ
QGELAGLDRAAKRITLSPVNDSDGAELLPARELEYDTLVIAIGSTTHFFGVQGAPENAIALDTVGEAERFRKRLIAACMR
AEHQAPAAVAPGEPAEPRIQVVIVGGGATGVELSAELRNTAQVLSVYGLHKLDPRHDVGIVLIESGPRILPALPERVSSA
TAELLEKLGVRLMLGERVTEVAPGAVHTASGKAVRADLTVWAAGIKAPAVLAHLDGLQVNKLGQLDVRRTLQTVTDDNVF
ALGDCAACAWPGSERNVPPRAQAAHQQASFLLKAIACRLDGRPLPEFTYRDFGSLVSLGHFSAVGNLMGGLIGGNMLIEG
LFARFMYMSLYRLHIAALHGYPRMILDTVAHWLRRTTLPRVKLH

Sequences:

>Translated_444_residues
MHRIIIVGGGAGGLELATRLGDRYGARGNRPARALVTLVDRNPTHIWKPLLHEVAAGSMDPFTQELEYAAQARWHGFEFQ
QGELAGLDRAAKRITLSPVNDSDGAELLPARELEYDTLVIAIGSTTHFFGVQGAPENAIALDTVGEAERFRKRLIAACMR
AEHQAPAAVAPGEPAEPRIQVVIVGGGATGVELSAELRNTAQVLSVYGLHKLDPRHDVGIVLIESGPRILPALPERVSSA
TAELLEKLGVRLMLGERVTEVAPGAVHTASGKAVRADLTVWAAGIKAPAVLAHLDGLQVNKLGQLDVRRTLQTVTDDNVF
ALGDCAACAWPGSERNVPPRAQAAHQQASFLLKAIACRLDGRPLPEFTYRDFGSLVSLGHFSAVGNLMGGLIGGNMLIEG
LFARFMYMSLYRLHIAALHGYPRMILDTVAHWLRRTTLPRVKLH
>Mature_444_residues
MHRIIIVGGGAGGLELATRLGDRYGARGNRPARALVTLVDRNPTHIWKPLLHEVAAGSMDPFTQELEYAAQARWHGFEFQ
QGELAGLDRAAKRITLSPVNDSDGAELLPARELEYDTLVIAIGSTTHFFGVQGAPENAIALDTVGEAERFRKRLIAACMR
AEHQAPAAVAPGEPAEPRIQVVIVGGGATGVELSAELRNTAQVLSVYGLHKLDPRHDVGIVLIESGPRILPALPERVSSA
TAELLEKLGVRLMLGERVTEVAPGAVHTASGKAVRADLTVWAAGIKAPAVLAHLDGLQVNKLGQLDVRRTLQTVTDDNVF
ALGDCAACAWPGSERNVPPRAQAAHQQASFLLKAIACRLDGRPLPEFTYRDFGSLVSLGHFSAVGNLMGGLIGGNMLIEG
LFARFMYMSLYRLHIAALHGYPRMILDTVAHWLRRTTLPRVKLH

Specific function: Transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Does not couple the redox reaction to proton translocation [H]

COG id: COG1252

COG function: function code C; NADH dehydrogenase, FAD-containing subunit

Gene ontology:

Cell location: Cell membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787352, Length=444, Percent_Identity=47.7477477477478, Blast_Score=390, Evalue=1e-110,
Organism=Saccharomyces cerevisiae, GI6320118, Length=448, Percent_Identity=23.4375, Blast_Score=83, Evalue=9e-17,
Organism=Saccharomyces cerevisiae, GI6323794, Length=367, Percent_Identity=25.6130790190736, Blast_Score=74, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6323515, Length=458, Percent_Identity=23.5807860262009, Blast_Score=71, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.6.99.3 [H]

Molecular weight: Translated: 47849; Mature: 47849

Theoretical pI: Translated: 8.07; Mature: 8.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHRIIIVGGGAGGLELATRLGDRYGARGNRPARALVTLVDRNPTHIWKPLLHEVAAGSMD
CEEEEEEECCCCHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHCCCCC
PFTQELEYAAQARWHGFEFQQGELAGLDRAAKRITLSPVNDSDGAELLPARELEYDTLVI
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHEEEEECCCCCCCCCCCCCCCCCCCEEEE
AIGSTTHFFGVQGAPENAIALDTVGEAERFRKRLIAACMRAEHQAPAAVAPGEPAEPRIQ
EECCCEEEEECCCCCCCCEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEE
VVIVGGGATGVELSAELRNTAQVLSVYGLHKLDPRHDVGIVLIESGPRILPALPERVSSA
EEEEECCCCCCEEHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHH
TAELLEKLGVRLMLGERVTEVAPGAVHTASGKAVRADLTVWAAGIKAPAVLAHLDGLQVN
HHHHHHHCCCEEEECCHHHHHCCCCEEECCCCEEEEEHEEEECCCCCCHHHHHCCCCCCC
KLGQLDVRRTLQTVTDDNVFALGDCAACAWPGSERNVPPRAQAAHQQASFLLKAIACRLD
CCCHHHHHHHHHHHCCCCEEEECCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
GRPLPEFTYRDFGSLVSLGHFSAVGNLMGGLIGGNMLIEGLFARFMYMSLYRLHIAALHG
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
YPRMILDTVAHWLRRTTLPRVKLH
CHHHHHHHHHHHHHHCCCCCEECC
>Mature Secondary Structure
MHRIIIVGGGAGGLELATRLGDRYGARGNRPARALVTLVDRNPTHIWKPLLHEVAAGSMD
CEEEEEEECCCCHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHCCCCC
PFTQELEYAAQARWHGFEFQQGELAGLDRAAKRITLSPVNDSDGAELLPARELEYDTLVI
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHEEEEECCCCCCCCCCCCCCCCCCCEEEE
AIGSTTHFFGVQGAPENAIALDTVGEAERFRKRLIAACMRAEHQAPAAVAPGEPAEPRIQ
EECCCEEEEECCCCCCCCEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEE
VVIVGGGATGVELSAELRNTAQVLSVYGLHKLDPRHDVGIVLIESGPRILPALPERVSSA
EEEEECCCCCCEEHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHH
TAELLEKLGVRLMLGERVTEVAPGAVHTASGKAVRADLTVWAAGIKAPAVLAHLDGLQVN
HHHHHHHCCCEEEECCHHHHHCCCCEEECCCCEEEEEHEEEECCCCCCHHHHHCCCCCCC
KLGQLDVRRTLQTVTDDNVFALGDCAACAWPGSERNVPPRAQAAHQQASFLLKAIACRLD
CCCHHHHHHHHHHHCCCCEEEECCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
GRPLPEFTYRDFGSLVSLGHFSAVGNLMGGLIGGNMLIEGLFARFMYMSLYRLHIAALHG
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
YPRMILDTVAHWLRRTTLPRVKLH
CHHHHHHHHHHHHHHCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 6265208; 8905232; 9278503 [H]