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The map label for this gene is thiE

Identifier: 189352401

GI number: 189352401

Start: 459430

End: 460014

Strand: Reverse

Name: thiE

Synonym: BMULJ_03620

Alternate gene names: NA

Gene position: 460014-459430 (Counterclockwise)

Preceding gene: 189352402

Following gene: 189352399

Centisome position: 18.6

GC content: 73.16

Gene sequence:

>585_bases
ATGAAGCCCGCGCTGCCGCGCCGCTACGTCATCACGCCGGAGCCGGCTTCCGCATCGGCGGCCGATTGCGATGCGTTTCT
CGATCGGCTGTCCGCCGTGCTCGCGCGCGGCGACACGCTCGTGCAACTGCGCGTGAAGTCGTTCGACGCGGCGGCGTTCG
CGCGGCTCGCGGCCGACGCGCTCGCCCGCTGCGAGGCCGCCGGCGCGCAGTTGATGCTGAACGGGCCGATCGACGCGCAC
GGTGTGTTGCAGCTCGAACACGCCGGCTGGCATCTCGACGGCGCGACGCTGCGTGCGACGCAGCAGCGGCCGCTGCCGGC
CGACCGGCTGCTATCCGCCGCCTGTCATGACGCCGACGATCTGCGGCTCGCCGCACGCGCGGGCGCCGACTTCGTCACGC
TGTCGCCGGTGCTGCCGACGCTGAGCCATCCGGGCGCACCGACGCTCGGCTGGGCGCAGTTCGGCGCGTGGGCCGCTCAG
GCCGCGATGCCGGTCTACGCGCTCGGCGGCATGACGCACGCGCATCTCGACGAAGCGCGCCGCCGTCACGCCTACGGAAT
CGCCGGCATTCGCGGCTTCTGGTAA

Upstream 100 bases:

>100_bases
GTCGTGAAGAAGATGAACGGGCCGCGCATCGTGCTCGTGCGCGTGTATCCGAAGGTCGCGAAGGAGGCCGACGAGTGACG
GCCTCGCAGCGCCGCGTGCC

Downstream 100 bases:

>100_bases
GCGATCCGCAGACCGCACACTCAACGCCCTATCCGCTCACGCATTCAGGCCGGCGCGCGGCGCACGCACCGTCATGCCGA
AGTCGATGCGTCTCGCATCG

Product: thiamine-phosphate pyrophosphorylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 194; Mature: 194

Protein sequence:

>194_residues
MKPALPRRYVITPEPASASAADCDAFLDRLSAVLARGDTLVQLRVKSFDAAAFARLAADALARCEAAGAQLMLNGPIDAH
GVLQLEHAGWHLDGATLRATQQRPLPADRLLSAACHDADDLRLAARAGADFVTLSPVLPTLSHPGAPTLGWAQFGAWAAQ
AAMPVYALGGMTHAHLDEARRRHAYGIAGIRGFW

Sequences:

>Translated_194_residues
MKPALPRRYVITPEPASASAADCDAFLDRLSAVLARGDTLVQLRVKSFDAAAFARLAADALARCEAAGAQLMLNGPIDAH
GVLQLEHAGWHLDGATLRATQQRPLPADRLLSAACHDADDLRLAARAGADFVTLSPVLPTLSHPGAPTLGWAQFGAWAAQ
AAMPVYALGGMTHAHLDEARRRHAYGIAGIRGFW
>Mature_194_residues
MKPALPRRYVITPEPASASAADCDAFLDRLSAVLARGDTLVQLRVKSFDAAAFARLAADALARCEAAGAQLMLNGPIDAH
GVLQLEHAGWHLDGATLRATQQRPLPADRLLSAACHDADDLRLAARAGADFVTLSPVLPTLSHPGAPTLGWAQFGAWAAQ
AAMPVYALGGMTHAHLDEARRRHAYGIAGIRGFW

Specific function: Unknown

COG id: COG0352

COG function: function code H; Thiamine monophosphate synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TMP-PPase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR022998
- InterPro:   IPR003733 [H]

Pfam domain/function: PF02581 TMP-TENI [H]

EC number: NA

Molecular weight: Translated: 20532; Mature: 20532

Theoretical pI: Translated: 7.67; Mature: 7.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPALPRRYVITPEPASASAADCDAFLDRLSAVLARGDTLVQLRVKSFDAAAFARLAADA
CCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHH
LARCEAAGAQLMLNGPIDAHGVLQLEHAGWHLDGATLRATQQRPLPADRLLSAACHDADD
HHHHHHCCCEEEEECCCCCCCEEEEECCCEEECCCEEEECCCCCCCHHHHHHHHHCCCHH
LRLAARAGADFVTLSPVLPTLSHPGAPTLGWAQFGAWAAQAAMPVYALGGMTHAHLDEAR
HHHHHHCCCCEEEECCCCHHCCCCCCCCCCHHHHHHHHHHHHCCHHHHCCCCHHHHHHHH
RRHAYGIAGIRGFW
HHHHCCCCCCCCCC
>Mature Secondary Structure
MKPALPRRYVITPEPASASAADCDAFLDRLSAVLARGDTLVQLRVKSFDAAAFARLAADA
CCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHH
LARCEAAGAQLMLNGPIDAHGVLQLEHAGWHLDGATLRATQQRPLPADRLLSAACHDADD
HHHHHHCCCEEEEECCCCCCCEEEEECCCEEECCCEEEECCCCCCCHHHHHHHHHCCCHH
LRLAARAGADFVTLSPVLPTLSHPGAPTLGWAQFGAWAAQAAMPVYALGGMTHAHLDEAR
HHHHHHCCCCEEEECCCCHHCCCCCCCCCCHHHHHHHHHHHHCCHHHHCCCCHHHHHHHH
RRHAYGIAGIRGFW
HHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]