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The map label for this gene is polB [H]

Identifier: 189352045

GI number: 189352045

Start: 61368

End: 63743

Strand: Reverse

Name: polB [H]

Synonym: BMULJ_03262

Alternate gene names: 189352045

Gene position: 63743-61368 (Counterclockwise)

Preceding gene: 189352046

Following gene: 189352044

Centisome position: 2.58

GC content: 67.63

Gene sequence:

>2376_bases
TTGACGGAGTTCGAGCAAGGTTTCATCCTCACCCGACACTGGCGTGACACGTCGGCCGGCGTCGAAGTCGAGTTCTGGCT
GGCGACCGAGCACGGGCCGCGCCGCGTGCGGCTGCGTCCGCAAGAGGCGGTCGCGTTCGTGCCCGCCGAACAGCAGCCGC
TCGCCGAACGCGTGCTCGCCGGCGAGCGCGACGCCGAGCTGCGCCCGCTCGCGCTGCGCGATTTCCGGAAGCGCGCCGTC
GTCGGCCTGTACTGCCGGCGCTACCGGCATCTGACTGCGCTGCAGAAACGGCTCGCGGCGGCCGGCGTCGACGTCTACGA
AGCCGACGTACAACCGCCCGACCGCTACACGATGGAGCGCTTCATCACCGCGCCGGTGCGGTTTCGAGGCCGGCCCGGCG
ATGCGCGCACGCTCGTCGATGCGGAACTGAAAGCCGCGACCGACTATCGCCCCGCGCTGCGCTGCGTGTCGCTCGACATC
GAAACGAGCGTGCACGGCGATCTCTATTCGATCGCGCTCGAAGGCTGCGGACAACGACAGGTGTTCATGCTCGGGCCGCC
GAACGGCGACGCGGCCGAAGCCCGCGATTTCGGCCTCGACTACTGCGACGACCGCGCGACGATGCTCGCGCGCCTCAACG
ACTGGTTCGACGCGCACGATCCCGACGCGATCATCGGCTGGAACCTCGTGCAGTTCGACCTGCGCGTGCTGCATGCGCAT
GCGGAGCAGCTCGGCGTGCCGCTGAAGCTCGGCCGCGGCGGCAGCGTGCTCGACTGGCGCGCGCACGGGCAGCAGCCCGA
TCATTTCTTCGCGGGCGCGGCCGGCCGGCTGATCCTCGACGGCATCGACATGCTGAAGTCCGCGACGTGGAGCTTCCCGT
CGTTCAGCCTCGAATACGTCGCGCAGCAACTGCTCGGCGAAGGCAAGTCGATCGACAACCCGTATCAGCGGATGGACGAA
ATCCAGCGCCGCTTCGATCACGACAAGCCGGCGCTCGCGCGCTACAACCTGAAGGACTGCGAGCTCGTCACGCGCATTTT
CGCGAAGGCCGACCTGCTGTCGTTCGCGCTCGAACGCGCGACCGTCACCGGGCTCGCGGCCGATCGCACCGGCGGCTCGG
TCGCCGCGTTCACGCATCTGTATCTGCCGCGCATGCATCGGCTCGGTTACGTCGCGCCGAATCTCGGCGACGTGACCGGG
CAGAACAGCCCCGGCGGCTTCGTGATGGATTCGCGGCCCGGCCTGTACGACTCGGTGCTCGTCTTCGACTACAAGAGCCT
GTATCCGTCGATCATCCGCACGTTCCTGATCGATCCGGTCGGACTCATCGAAGGGCTCGCGCATCCGGACGACGATGCGT
CGGTGCCCGGCTTTCTCGGCGCGCGCTTCTCGCGTACCGCGCACTGTCTGCCCGACATCGTGCGGCGCGTGTGGGAAGGC
CGCGACGACGCGAAGCGCCAGCGCAACGCGCCGCTCTCGCAGGCGTTGAAGATCATCATGAACTCGTTCTACGGCGTGCT
CGGTTCGACCGGCTGCCGGTTCTTCGATCCGCGTCTCGCGTCGTCGATCACGATGCGCGGCCACGAGATCATGCATCGCA
CGCGCGAACTGATCGAGGCGCAGGGCTTCGACGTGATCTATGGCGATACCGATTCGACCTTCGTCTGGCTCGGCCGCGCG
CACGACGACGACGAGGCCGCGCGCAAGGGCCGTGCACTCGTCGCACATGTGAACGGCTGGTGGCGCACGCATCTGCGCGA
ACGCTTCGGGCTCGACAGCGCGCTCGAGCTGCAATACGAACGGCATTACCGCCGCTTCCTGATGCCGACCGTGCGCGGCG
CGGAGGAAGGCAGCAAGAAGCGCTATGCGGGGCTCGCCGCTGCGGCCGACGGCAGCGAAGACCTCGTGTTCAAGGGACTC
GAAACGGTCCGTACCGACTGGACGCCGCTCGCGCAGCAGTTCCAGCGCGAGCTGTATCGTCGCGTGTTCCGGCGCGAGCC
CTATCGGGACTTCATCCGCGACTACGTGCAGCGCACGCTCGCCGGCGAATTCGACGCGCTGCTCGTCTATCGGAAGCGCG
TGCGCCGGCCGCTGCGCGAATATCAGCGCAACGTGCCGCCGCACGTGCGCGCGGCGCGGATCGCCGACGAATTCAATCAG
GCCAACGGCCGGCCGCTTCAATATCAGCGCGGCGGCTGGATCAGCTACGTGATGACGACGGCCGGGCCCGAGCCGCTCGA
AGCGACGCACGCGCCGATCGACTACGCGTTCTATGTGAGCCGGCAGCTGCAGCCCGTCGCCGATGCGATCCTGCCGTTTC
TGCGCGACGATTTCGAACGCGTCGTGTCGGGGCAAGGGCAGCTGTTTCTCGAATGA

Upstream 100 bases:

>100_bases
CTGCCGCGCCGTGCAGCGCGGCGCAGGCGTGCGGCGTGCGGCGTGCCGCGTGCGCAGGCGCTACAATCCGCCGCCTGGGC
ATCCATCGCGAGCGTGCGTT

Downstream 100 bases:

>100_bases
ACGCGGATCCGGCCAGCTAGAATAGCGGCCTGCTGCGCGTTCCGCCGCAGCCGGAGGACACCATCATGACCGCACGTCGC
GGCACCGCGGTCGCCATCGC

Product: DNA polymerase II

Products: NA

Alternate protein names: Pol II [H]

Number of amino acids: Translated: 791; Mature: 790

Protein sequence:

>791_residues
MTEFEQGFILTRHWRDTSAGVEVEFWLATEHGPRRVRLRPQEAVAFVPAEQQPLAERVLAGERDAELRPLALRDFRKRAV
VGLYCRRYRHLTALQKRLAAAGVDVYEADVQPPDRYTMERFITAPVRFRGRPGDARTLVDAELKAATDYRPALRCVSLDI
ETSVHGDLYSIALEGCGQRQVFMLGPPNGDAAEARDFGLDYCDDRATMLARLNDWFDAHDPDAIIGWNLVQFDLRVLHAH
AEQLGVPLKLGRGGSVLDWRAHGQQPDHFFAGAAGRLILDGIDMLKSATWSFPSFSLEYVAQQLLGEGKSIDNPYQRMDE
IQRRFDHDKPALARYNLKDCELVTRIFAKADLLSFALERATVTGLAADRTGGSVAAFTHLYLPRMHRLGYVAPNLGDVTG
QNSPGGFVMDSRPGLYDSVLVFDYKSLYPSIIRTFLIDPVGLIEGLAHPDDDASVPGFLGARFSRTAHCLPDIVRRVWEG
RDDAKRQRNAPLSQALKIIMNSFYGVLGSTGCRFFDPRLASSITMRGHEIMHRTRELIEAQGFDVIYGDTDSTFVWLGRA
HDDDEAARKGRALVAHVNGWWRTHLRERFGLDSALELQYERHYRRFLMPTVRGAEEGSKKRYAGLAAAADGSEDLVFKGL
ETVRTDWTPLAQQFQRELYRRVFRREPYRDFIRDYVQRTLAGEFDALLVYRKRVRRPLREYQRNVPPHVRAARIADEFNQ
ANGRPLQYQRGGWISYVMTTAGPEPLEATHAPIDYAFYVSRQLQPVADAILPFLRDDFERVVSGQGQLFLE

Sequences:

>Translated_791_residues
MTEFEQGFILTRHWRDTSAGVEVEFWLATEHGPRRVRLRPQEAVAFVPAEQQPLAERVLAGERDAELRPLALRDFRKRAV
VGLYCRRYRHLTALQKRLAAAGVDVYEADVQPPDRYTMERFITAPVRFRGRPGDARTLVDAELKAATDYRPALRCVSLDI
ETSVHGDLYSIALEGCGQRQVFMLGPPNGDAAEARDFGLDYCDDRATMLARLNDWFDAHDPDAIIGWNLVQFDLRVLHAH
AEQLGVPLKLGRGGSVLDWRAHGQQPDHFFAGAAGRLILDGIDMLKSATWSFPSFSLEYVAQQLLGEGKSIDNPYQRMDE
IQRRFDHDKPALARYNLKDCELVTRIFAKADLLSFALERATVTGLAADRTGGSVAAFTHLYLPRMHRLGYVAPNLGDVTG
QNSPGGFVMDSRPGLYDSVLVFDYKSLYPSIIRTFLIDPVGLIEGLAHPDDDASVPGFLGARFSRTAHCLPDIVRRVWEG
RDDAKRQRNAPLSQALKIIMNSFYGVLGSTGCRFFDPRLASSITMRGHEIMHRTRELIEAQGFDVIYGDTDSTFVWLGRA
HDDDEAARKGRALVAHVNGWWRTHLRERFGLDSALELQYERHYRRFLMPTVRGAEEGSKKRYAGLAAAADGSEDLVFKGL
ETVRTDWTPLAQQFQRELYRRVFRREPYRDFIRDYVQRTLAGEFDALLVYRKRVRRPLREYQRNVPPHVRAARIADEFNQ
ANGRPLQYQRGGWISYVMTTAGPEPLEATHAPIDYAFYVSRQLQPVADAILPFLRDDFERVVSGQGQLFLE
>Mature_790_residues
TEFEQGFILTRHWRDTSAGVEVEFWLATEHGPRRVRLRPQEAVAFVPAEQQPLAERVLAGERDAELRPLALRDFRKRAVV
GLYCRRYRHLTALQKRLAAAGVDVYEADVQPPDRYTMERFITAPVRFRGRPGDARTLVDAELKAATDYRPALRCVSLDIE
TSVHGDLYSIALEGCGQRQVFMLGPPNGDAAEARDFGLDYCDDRATMLARLNDWFDAHDPDAIIGWNLVQFDLRVLHAHA
EQLGVPLKLGRGGSVLDWRAHGQQPDHFFAGAAGRLILDGIDMLKSATWSFPSFSLEYVAQQLLGEGKSIDNPYQRMDEI
QRRFDHDKPALARYNLKDCELVTRIFAKADLLSFALERATVTGLAADRTGGSVAAFTHLYLPRMHRLGYVAPNLGDVTGQ
NSPGGFVMDSRPGLYDSVLVFDYKSLYPSIIRTFLIDPVGLIEGLAHPDDDASVPGFLGARFSRTAHCLPDIVRRVWEGR
DDAKRQRNAPLSQALKIIMNSFYGVLGSTGCRFFDPRLASSITMRGHEIMHRTRELIEAQGFDVIYGDTDSTFVWLGRAH
DDDEAARKGRALVAHVNGWWRTHLRERFGLDSALELQYERHYRRFLMPTVRGAEEGSKKRYAGLAAAADGSEDLVFKGLE
TVRTDWTPLAQQFQRELYRRVFRREPYRDFIRDYVQRTLAGEFDALLVYRKRVRRPLREYQRNVPPHVRAARIADEFNQA
NGRPLQYQRGGWISYVMTTAGPEPLEATHAPIDYAFYVSRQLQPVADAILPFLRDDFERVVSGQGQLFLE

Specific function: Thought to be involved in DNA repair and/or mutagenesis [H]

COG id: COG0417

COG function: function code L; DNA polymerase elongation subunit (family B)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DNA polymerase type-B family [H]

Homologues:

Organism=Homo sapiens, GI156616275, Length=628, Percent_Identity=27.2292993630573, Blast_Score=131, Evalue=3e-30,
Organism=Homo sapiens, GI106507301, Length=630, Percent_Identity=24.6031746031746, Blast_Score=130, Evalue=4e-30,
Organism=Escherichia coli, GI1786246, Length=785, Percent_Identity=66.3694267515924, Blast_Score=1066, Evalue=0.0,
Organism=Caenorhabditis elegans, GI32565317, Length=637, Percent_Identity=24.9607535321821, Blast_Score=135, Evalue=7e-32,
Organism=Caenorhabditis elegans, GI17559488, Length=709, Percent_Identity=26.0930888575458, Blast_Score=132, Evalue=5e-31,
Organism=Saccharomyces cerevisiae, GI6324227, Length=589, Percent_Identity=26.1460101867572, Blast_Score=116, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6320101, Length=627, Percent_Identity=25.0398724082935, Blast_Score=114, Evalue=7e-26,
Organism=Drosophila melanogaster, GI24648780, Length=656, Percent_Identity=24.5426829268293, Blast_Score=127, Evalue=3e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006172
- InterPro:   IPR017964
- InterPro:   IPR006133
- InterPro:   IPR006134
- InterPro:   IPR023211
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00136 DNA_pol_B; PF03104 DNA_pol_B_exo [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 89833; Mature: 89702

Theoretical pI: Translated: 7.54; Mature: 7.54

Prosite motif: PS00116 DNA_POLYMERASE_B

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEFEQGFILTRHWRDTSAGVEVEFWLATEHGPRRVRLRPQEAVAFVPAEQQPLAERVLA
CCCCCCCCEEEEECCCCCCCEEEEEEEECCCCCCEEEECHHHCEEECCCCCCHHHHHHHC
GERDAELRPLALRDFRKRAVVGLYCRRYRHLTALQKRLAAAGVDVYEADVQPPDRYTMER
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCHHHHHH
FITAPVRFRGRPGDARTLVDAELKAATDYRPALRCVSLDIETSVHGDLYSIALEGCGQRQ
HHCCCCEECCCCCCCCEEEHHHHHHHCCCCHHHEEEEEEECCCCCCHHHHHHHHCCCCCE
VFMLGPPNGDAAEARDFGLDYCDDRATMLARLNDWFDAHDPDAIIGWNLVQFDLRVLHAH
EEEEECCCCCCCHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCEECCHHHHHHHHHHHHH
AEQLGVPLKLGRGGSVLDWRAHGQQPDHFFAGAAGRLILDGIDMLKSATWSFPSFSLEYV
HHHHCCCEEECCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHH
AQQLLGEGKSIDNPYQRMDEIQRRFDHDKPALARYNLKDCELVTRIFAKADLLSFALERA
HHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
TVTGLAADRTGGSVAAFTHLYLPRMHRLGYVAPNLGDVTGQNSPGGFVMDSRPGLYDSVL
HHHCEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEECCCCCCHHHHH
VFDYKSLYPSIIRTFLIDPVGLIEGLAHPDDDASVPGFLGARFSRTAHCLPDIVRRVWEG
HHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
RDDAKRQRNAPLSQALKIIMNSFYGVLGSTGCRFFDPRLASSITMRGHEIMHRTRELIEA
CCHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHH
QGFDVIYGDTDSTFVWLGRAHDDDEAARKGRALVAHVNGWWRTHLRERFGLDSALELQYE
CCCEEEECCCCCEEEEEECCCCCHHHHHCCCEEEEECCHHHHHHHHHHHCCCHHHHHHHH
RHYRRFLMPTVRGAEEGSKKRYAGLAAAADGSEDLVFKGLETVRTDWTPLAQQFQRELYR
HHHHHHHHHHHCCCCCCCHHHHHCEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHH
RVFRREPYRDFIRDYVQRTLAGEFDALLVYRKRVRRPLREYQRNVPPHVRAARIADEFNQ
HHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHC
ANGRPLQYQRGGWISYVMTTAGPEPLEATHAPIDYAFYVSRQLQPVADAILPFLRDDFER
CCCCCEEEECCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHH
VVSGQGQLFLE
HHCCCCCEEEC
>Mature Secondary Structure 
TEFEQGFILTRHWRDTSAGVEVEFWLATEHGPRRVRLRPQEAVAFVPAEQQPLAERVLA
CCCCCCCEEEEECCCCCCCEEEEEEEECCCCCCEEEECHHHCEEECCCCCCHHHHHHHC
GERDAELRPLALRDFRKRAVVGLYCRRYRHLTALQKRLAAAGVDVYEADVQPPDRYTMER
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCHHHHHH
FITAPVRFRGRPGDARTLVDAELKAATDYRPALRCVSLDIETSVHGDLYSIALEGCGQRQ
HHCCCCEECCCCCCCCEEEHHHHHHHCCCCHHHEEEEEEECCCCCCHHHHHHHHCCCCCE
VFMLGPPNGDAAEARDFGLDYCDDRATMLARLNDWFDAHDPDAIIGWNLVQFDLRVLHAH
EEEEECCCCCCCHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCEECCHHHHHHHHHHHHH
AEQLGVPLKLGRGGSVLDWRAHGQQPDHFFAGAAGRLILDGIDMLKSATWSFPSFSLEYV
HHHHCCCEEECCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHH
AQQLLGEGKSIDNPYQRMDEIQRRFDHDKPALARYNLKDCELVTRIFAKADLLSFALERA
HHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
TVTGLAADRTGGSVAAFTHLYLPRMHRLGYVAPNLGDVTGQNSPGGFVMDSRPGLYDSVL
HHHCEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEECCCCCCHHHHH
VFDYKSLYPSIIRTFLIDPVGLIEGLAHPDDDASVPGFLGARFSRTAHCLPDIVRRVWEG
HHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
RDDAKRQRNAPLSQALKIIMNSFYGVLGSTGCRFFDPRLASSITMRGHEIMHRTRELIEA
CCHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHH
QGFDVIYGDTDSTFVWLGRAHDDDEAARKGRALVAHVNGWWRTHLRERFGLDSALELQYE
CCCEEEECCCCCEEEEEECCCCCHHHHHCCCEEEEECCHHHHHHHHHHHCCCHHHHHHHH
RHYRRFLMPTVRGAEEGSKKRYAGLAAAADGSEDLVFKGLETVRTDWTPLAQQFQRELYR
HHHHHHHHHHHCCCCCCCHHHHHCEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHH
RVFRREPYRDFIRDYVQRTLAGEFDALLVYRKRVRRPLREYQRNVPPHVRAARIADEFNQ
HHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHC
ANGRPLQYQRGGWISYVMTTAGPEPLEATHAPIDYAFYVSRQLQPVADAILPFLRDDFER
CCCCCEEEECCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHH
VVSGQGQLFLE
HHCCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2034216; 2261080; 1630901; 9278503; 2217198; 9079692 [H]