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The map label for this gene is yrpG [H]

Identifier: 189352004

GI number: 189352004

Start: 24148

End: 25095

Strand: Reverse

Name: yrpG [H]

Synonym: BMULJ_03221

Alternate gene names: 189352004

Gene position: 25095-24148 (Counterclockwise)

Preceding gene: 189352005

Following gene: 189352002

Centisome position: 1.01

GC content: 65.82

Gene sequence:

>948_bases
ATGGCCCTACGCACCCTCGGCACGTCCAGCATTCAGGTTTCGCCGCTCGCATTCGGCGGCAATGTGTTCGGCTGGACCGT
CGACGAGAACGCGTCGTTTTCGCTGCTCGACGCGCTCGCCGACACCGGCATCAATTTCATCGACACCGCCGACGTCTACT
CGGCCTGGGCGCCCGGCAATCGCGGCGGCGAATCGGAAACCATCATCGGCAAATGGCTTAAGCGCACGGGCAAGCGCGAA
CAGGTCGTGATCGCGACCAAGGTCGGCATGCTCGAAGCGCGCGCGGGCCTGTCGAAAGACAACATTCTGAAAGCCGCCGA
CGATTCGCTGCGCCGCCTGCAGACCGACTACATCGACCTGTACTTCTCGCATCGCGATCTGCCCGAGACGGCGCCGCTCG
AGGAAACGCTCGCCGCGTATCAGGCGCTGATCGACGCAGGAAAAGTGCGGATCATCGGCGCCTCGAACTACAGCGGTGCG
CGTCTGCGCGAGGCGGCCGAGATCAGCCGGCGCGACGGCCTGCCCACGTACCAGGTGATCCAGCCCGAATACAACCTGTA
CGACCGCGCCGAATACGAGCGCGATCTCGAGCCGGTCGTGCGCGACCTGAAGCTCGGCGTCGTCAACTACTACGCGCTGG
CGAGCGGTTTTCTGTCGGGCAAGTACCGTAGCGAAGCCGATCTGAAGAAGAGCGTGCGCGGCAGCCGCGTCGCCGGCTAT
CTCGATGCGCGCGGGCTGCGCATTCTCGCGGCGCTCGACGCGGTATCGGCGAAGCACGGCACGCAGCCGGCCGCGATCGC
GCTCGCGTGGCAGATCGCGCGGCCGACGATCACGGCGCCGATCGCCAGCGCGACGTCGCTTGCGCAACTTGCACTACTCG
GCGATGCGCTGCGCGTGCAGCTCGATCAGGACGACATCCGGCAGATCGACGAAGCGAGTGCGGTTTGA

Upstream 100 bases:

>100_bases
CGACACGATGCCGCGCACGCCGCTGCGCTGCGATGCCGACGCCCCACGCCGATGTCGCTCGCGTGGCTCCGTTCCGTCAA
TCGCATACACGGAGAGAAAG

Downstream 100 bases:

>100_bases
GCGCACGCTCGGCGAGCGCGTCGCGCGGCGTTCGTGCGACCGGTGCGGCGGCGCGGTTGGTGTCAGCGCTCGCCGGACGG
CACCGCGTCGCGCAACGCCA

Product: NADP-dependent aryl-alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 315; Mature: 314

Protein sequence:

>315_residues
MALRTLGTSSIQVSPLAFGGNVFGWTVDENASFSLLDALADTGINFIDTADVYSAWAPGNRGGESETIIGKWLKRTGKRE
QVVIATKVGMLEARAGLSKDNILKAADDSLRRLQTDYIDLYFSHRDLPETAPLEETLAAYQALIDAGKVRIIGASNYSGA
RLREAAEISRRDGLPTYQVIQPEYNLYDRAEYERDLEPVVRDLKLGVVNYYALASGFLSGKYRSEADLKKSVRGSRVAGY
LDARGLRILAALDAVSAKHGTQPAAIALAWQIARPTITAPIASATSLAQLALLGDALRVQLDQDDIRQIDEASAV

Sequences:

>Translated_315_residues
MALRTLGTSSIQVSPLAFGGNVFGWTVDENASFSLLDALADTGINFIDTADVYSAWAPGNRGGESETIIGKWLKRTGKRE
QVVIATKVGMLEARAGLSKDNILKAADDSLRRLQTDYIDLYFSHRDLPETAPLEETLAAYQALIDAGKVRIIGASNYSGA
RLREAAEISRRDGLPTYQVIQPEYNLYDRAEYERDLEPVVRDLKLGVVNYYALASGFLSGKYRSEADLKKSVRGSRVAGY
LDARGLRILAALDAVSAKHGTQPAAIALAWQIARPTITAPIASATSLAQLALLGDALRVQLDQDDIRQIDEASAV
>Mature_314_residues
ALRTLGTSSIQVSPLAFGGNVFGWTVDENASFSLLDALADTGINFIDTADVYSAWAPGNRGGESETIIGKWLKRTGKREQ
VVIATKVGMLEARAGLSKDNILKAADDSLRRLQTDYIDLYFSHRDLPETAPLEETLAAYQALIDAGKVRIIGASNYSGAR
LREAAEISRRDGLPTYQVIQPEYNLYDRAEYERDLEPVVRDLKLGVVNYYALASGFLSGKYRSEADLKKSVRGSRVAGYL
DARGLRILAALDAVSAKHGTQPAAIALAWQIARPTITAPIASATSLAQLALLGDALRVQLDQDDIRQIDEASAV

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=327, Percent_Identity=30.8868501529052, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI4504825, Length=324, Percent_Identity=30.8641975308642, Blast_Score=133, Evalue=3e-31,
Organism=Homo sapiens, GI27436962, Length=324, Percent_Identity=28.7037037037037, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI27436971, Length=324, Percent_Identity=29.6296296296296, Blast_Score=123, Evalue=2e-28,
Organism=Homo sapiens, GI27436964, Length=324, Percent_Identity=28.3950617283951, Blast_Score=122, Evalue=4e-28,
Organism=Homo sapiens, GI27436966, Length=302, Percent_Identity=29.1390728476821, Blast_Score=122, Evalue=6e-28,
Organism=Homo sapiens, GI223718702, Length=211, Percent_Identity=34.1232227488152, Blast_Score=88, Evalue=8e-18,
Organism=Homo sapiens, GI41327764, Length=188, Percent_Identity=35.6382978723404, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI41152114, Length=211, Percent_Identity=34.5971563981043, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI223718708, Length=168, Percent_Identity=33.3333333333333, Blast_Score=70, Evalue=4e-12,
Organism=Escherichia coli, GI87081735, Length=321, Percent_Identity=33.9563862928349, Blast_Score=155, Evalue=3e-39,
Organism=Escherichia coli, GI1789199, Length=341, Percent_Identity=30.2052785923754, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1788070, Length=336, Percent_Identity=30.0595238095238, Blast_Score=111, Evalue=6e-26,
Organism=Escherichia coli, GI1789375, Length=328, Percent_Identity=28.0487804878049, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1788081, Length=293, Percent_Identity=30.0341296928328, Blast_Score=91, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI212645785, Length=182, Percent_Identity=32.4175824175824, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6323998, Length=331, Percent_Identity=28.7009063444109, Blast_Score=113, Evalue=4e-26,
Organism=Saccharomyces cerevisiae, GI6319958, Length=300, Percent_Identity=27.6666666666667, Blast_Score=108, Evalue=8e-25,
Organism=Saccharomyces cerevisiae, GI6325169, Length=337, Percent_Identity=28.1899109792285, Blast_Score=105, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6319951, Length=332, Percent_Identity=26.8072289156627, Blast_Score=101, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6322615, Length=246, Percent_Identity=25.2032520325203, Blast_Score=75, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6321052, Length=168, Percent_Identity=33.3333333333333, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24640980, Length=314, Percent_Identity=26.7515923566879, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI45549126, Length=314, Percent_Identity=26.7515923566879, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24646155, Length=236, Percent_Identity=30.9322033898305, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24646159, Length=184, Percent_Identity=32.6086956521739, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 34176; Mature: 34045

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALRTLGTSSIQVSPLAFGGNVFGWTVDENASFSLLDALADTGINFIDTADVYSAWAPGN
CCCCCCCCCCEEEEEEEECCCEEEEEECCCCCHHHHHHHHHCCCCEEECHHHHHCCCCCC
RGGESETIIGKWLKRTGKREQVVIATKVGMLEARAGLSKDNILKAADDSLRRLQTDYIDL
CCCCCHHHHHHHHHHCCCCCEEEEEEECCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHEE
YFSHRDLPETAPLEETLAAYQALIDAGKVRIIGASNYSGARLREAAEISRRDGLPTYQVI
EECCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCEEEE
QPEYNLYDRAEYERDLEPVVRDLKLGVVNYYALASGFLSGKYRSEADLKKSVRGSRVAGY
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCEEEE
LDARGLRILAALDAVSAKHGTQPAAIALAWQIARPTITAPIASATSLAQLALLGDALRVQ
CCCCCEEEEHHHHHHHHHCCCCCCEEEEEEECCCCEECCCHHHHHHHHHHHHHHHHHEEE
LDQDDIRQIDEASAV
ECHHHHHHHHHHCCC
>Mature Secondary Structure 
ALRTLGTSSIQVSPLAFGGNVFGWTVDENASFSLLDALADTGINFIDTADVYSAWAPGN
CCCCCCCCCEEEEEEEECCCEEEEEECCCCCHHHHHHHHHCCCCEEECHHHHHCCCCCC
RGGESETIIGKWLKRTGKREQVVIATKVGMLEARAGLSKDNILKAADDSLRRLQTDYIDL
CCCCCHHHHHHHHHHCCCCCEEEEEEECCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHEE
YFSHRDLPETAPLEETLAAYQALIDAGKVRIIGASNYSGARLREAAEISRRDGLPTYQVI
EECCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCEEEE
QPEYNLYDRAEYERDLEPVVRDLKLGVVNYYALASGFLSGKYRSEADLKKSVRGSRVAGY
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCEEEE
LDARGLRILAALDAVSAKHGTQPAAIALAWQIARPTITAPIASATSLAQLALLGDALRVQ
CCCCCEEEEHHHHHHHHHCCCCCCEEEEEEECCCCEECCCHHHHHHHHHHHHHHHHHEEE
LDQDDIRQIDEASAV
ECHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9308178; 9384377 [H]