| Definition | Orientia tsutsugamushi str. Ikeda, complete genome. |
|---|---|
| Accession | NC_010793 |
| Length | 2,008,987 |
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The map label for this gene is uvrA [H]
Identifier: 189184314
GI number: 189184314
Start: 1441638
End: 1444511
Strand: Reverse
Name: uvrA [H]
Synonym: OTT_1407
Alternate gene names: 189184314
Gene position: 1444511-1441638 (Counterclockwise)
Preceding gene: 189184316
Following gene: 189184313
Centisome position: 71.9
GC content: 32.32
Gene sequence:
>2874_bases ATGGCTGATTGTATTAAAATACGGGGCGCAAGAGAGCATAACCTAAAAAATATTGATATAGATATCCCTAAACATAAATT AGTAGTTATTACTGGATTAAGTGGTTCTGGAAAATCATCTTTAGCATATGACACTATATATGCTGAGTCTATAAGAAGTT ATTTAGCAGGTTGGCCAGTGCGTAATATGCAGTTCTTTTCTTTGCAAAACAAATCAGATGTTGAATCTATTTCTGGTCTT TCTCCAGCTATTGCTATAGATCAAAAAACAATTTCTCGTAATCCTAGATCTACAGTCGGGACCATGACTGAAATATATGA CTATTTACGCTTACTATTTGCTAGAATAGGGATACCATATTCACCAGCTACTAATTCTCCAATTCAAGGACAAACTATTT CCGAGATGGTAGATATTATATGTGCTTTACCTCATGGAACTAAAATTGATATTCTTGTCCCAATTACTCAAGTTCATAAA GATAAATTCAATAAAGAGATATCTAGATTTAAAAAACATGGTTTTTCAAAGATAATAATTGATAACCATGAATATGAAAT AGATAATTTGCCAATACTAAACAAGTACGAAAAGCATAATATTTCAGTTATCGTTGATCAATTAGTTATTGATAACACGT TACGTAGCAAAATAACCTCTAGTTTAGAATCAGCATTGCAGTTATCAGATGGAATAATTTATGCTAAAAAAGTTACTTCC ACTTCTATGCAGAACAATAATGTTCAGTGCACTTTTCAGAACCAAGATGTTATAGTTTTATCAGAAAAGTACTCATGTCC AGTTTCAGGATTTCAGTTGCCAAAAATTGAGCCTCGTATGTTCTCATTTAATAGTCCATTTGGTGCTTGTAATACATGCA AAGGATTGGGCAAGGAGATGTTTTTTTCCACTGCACTAATTGTTCCTGATACCTCACTATCAATTGCTCAAGGCGCAATT TTGCCATGGGCTAATAATGATTCTTCTTTTATTAAAGATACTTTTAATGCTTTAGCCCAGCATTATAACTTTAGTCTTGA TGATCCTATTGAAAGTTTAAGTGATAAAGTTAAAAATGTTTTATTTTATGGATCAGGAGATGAAGAAATAAAGTTTACTT ATAATAGTGAAGCTAAGTCTAAGGTGGTTATTCAGCCATTTGGTGGAATAATTCCTAGTCTAGAGGAAAAATATTGTCAA GCTGCTACTCAGTGGATAAAAGATGAGTTGTTACGTTATCAGGTTGAAGGAGATTGTAGAGCATGTGGTGGAGACAGACT TACTCAAGAGTCATTATGTGTTAAAATTGCTAATCTAAATATTAGCGAAGTTGCAAAGATGAGAGTATCTGAAGCTTATG ATTGGTTTACTAACCTTGAGCATAGTTTAACAGAAACACATAAAATTATTGCGAAGCTAGTTATAAAAGAAATTAAGGAT AGGATATCTTTTTTAAAGAATGTAGGTTTAGAGTATTTAACAATTGATAGATCATCTACTACTCTGTCTGGTGGAGAAAG TCAACGTATTAGATTAGCATCACAAATAGGGTCAGGTTTGAGTGGAATAATGTATATTTTAGATGAACCATCTATAGGGT TGCATCAAAGTGATAATAAGAAGTTACTTTCTACTCTAAGAAATTTACAAAGTTTAGGAAATAGTCTTATTGTTGTTGAA CATGATAAAGAAACAATACTAGAAGCTGATCATATTATAGATGTTGGTCCTGGAGCTGGTACAGAAGGCGGAAAAATAGT TGCTCAAGGTGGAGTAAATGATATTATCAATGTTCCTGACAGTATTACTGGCCAATATTTAAGCGGTAAAAAATTTATTT CGATTCGAAGCAATGTAAGAATAGGTGATAATAATAGATCTATTGAACTTAAAGGAGCTAGATCTCATAATCTAAAAAAT GTTGATGTTAAAATACCTCTCGGTACCTTAACAGCAGTAACTGGAGTTTCTGGTAGCGGAAAATCAACACTCATTATTCA TACTCTATATAAAGCAATTTTAAAAAAACTTGAACCTAATACTAAAGGGTATGTTGGAGAGTATACTGATATTATAGGCT TAGATAATATAGATAAAGTGATCAATATTGATCAATCTCCTATTGGCAGGACTCCAAGATCTAATCCTGCTACTTACTCT GAAGTATTTAACTATATTCGTGATTGGTTTAGTGAGCTGCATGAAGCTAAAGCCCGAGGGTACAAACGTAGCAGATTTTC ATTTAATGTTAATGGTGGCCGTTGTGAAGCTTGCGAAGGATGTGGGTTAACTAGAATAGAAATGCACTTTTTACCAGATA TCTTTATAAACTGCGATGTGTGTGATGGAAACCGTTATAATAAAGAAACTTTAGAAATTAAATACAATGGAAAGTCTATA TCTGACGTACTAAATATGACAGTTGATAATGCTATAACGTTTTTTGATAAAGCTCCTCATATTCGTGATAAATTAAAAAC ATTAAATGAAGTAGGTTTAGGATATATTAAAATTGGGCAATCGGCTACAACACTTTCAGGAGGAGAAGCTCAGCGCATAA AACTTGCAAAAGAATTGTCAAAACGTTCCACTGGAAAAACATTATATATTTTAGATGAGCCAACTACAGGATTACATTTT GAAGATGTTAATAAGCTATTACAAATATTGCATAGGTTAGTTGATAATGGTAATACTGTATTAGTTATTGAGCATAATAT GGATGTTATTAAAAGTGCTGATTATATAGTAGATGTTGGTGTAGGAGGTGGTGATCAAGGAGGAGAAATAGTTGCCTTTG GTACTCCACAGCAAGTATCTTTTAATGATCAAAGTATTACAGGAGTATATTTAAGAGAATACTTTAATAAGTAG
Upstream 100 bases:
>100_bases TTATAATTGACTATCTAGTCAATTATAATTATGATTGCGACTATAGTTAAATAATATATGTTATTTGCTACTGAGTTATT GCGAAACATTAAAAATATGC
Downstream 100 bases:
>100_bases AGTTATCAGCTTAAGTTAATAGTCATTTACAATGAAGTTTGCGTATAAATATCCTGTTGGTTAATCTTATGATGCTATTG TCTCTTTTTTTATACTCAAA
Product: excinuclease ABC subunit A
Products: NA
Alternate protein names: UvrA protein; Excinuclease ABC subunit A [H]
Number of amino acids: Translated: 957; Mature: 956
Protein sequence:
>957_residues MADCIKIRGAREHNLKNIDIDIPKHKLVVITGLSGSGKSSLAYDTIYAESIRSYLAGWPVRNMQFFSLQNKSDVESISGL SPAIAIDQKTISRNPRSTVGTMTEIYDYLRLLFARIGIPYSPATNSPIQGQTISEMVDIICALPHGTKIDILVPITQVHK DKFNKEISRFKKHGFSKIIIDNHEYEIDNLPILNKYEKHNISVIVDQLVIDNTLRSKITSSLESALQLSDGIIYAKKVTS TSMQNNNVQCTFQNQDVIVLSEKYSCPVSGFQLPKIEPRMFSFNSPFGACNTCKGLGKEMFFSTALIVPDTSLSIAQGAI LPWANNDSSFIKDTFNALAQHYNFSLDDPIESLSDKVKNVLFYGSGDEEIKFTYNSEAKSKVVIQPFGGIIPSLEEKYCQ AATQWIKDELLRYQVEGDCRACGGDRLTQESLCVKIANLNISEVAKMRVSEAYDWFTNLEHSLTETHKIIAKLVIKEIKD RISFLKNVGLEYLTIDRSSTTLSGGESQRIRLASQIGSGLSGIMYILDEPSIGLHQSDNKKLLSTLRNLQSLGNSLIVVE HDKETILEADHIIDVGPGAGTEGGKIVAQGGVNDIINVPDSITGQYLSGKKFISIRSNVRIGDNNRSIELKGARSHNLKN VDVKIPLGTLTAVTGVSGSGKSTLIIHTLYKAILKKLEPNTKGYVGEYTDIIGLDNIDKVINIDQSPIGRTPRSNPATYS EVFNYIRDWFSELHEAKARGYKRSRFSFNVNGGRCEACEGCGLTRIEMHFLPDIFINCDVCDGNRYNKETLEIKYNGKSI SDVLNMTVDNAITFFDKAPHIRDKLKTLNEVGLGYIKIGQSATTLSGGEAQRIKLAKELSKRSTGKTLYILDEPTTGLHF EDVNKLLQILHRLVDNGNTVLVIEHNMDVIKSADYIVDVGVGGGDQGGEIVAFGTPQQVSFNDQSITGVYLREYFNK
Sequences:
>Translated_957_residues MADCIKIRGAREHNLKNIDIDIPKHKLVVITGLSGSGKSSLAYDTIYAESIRSYLAGWPVRNMQFFSLQNKSDVESISGL SPAIAIDQKTISRNPRSTVGTMTEIYDYLRLLFARIGIPYSPATNSPIQGQTISEMVDIICALPHGTKIDILVPITQVHK DKFNKEISRFKKHGFSKIIIDNHEYEIDNLPILNKYEKHNISVIVDQLVIDNTLRSKITSSLESALQLSDGIIYAKKVTS TSMQNNNVQCTFQNQDVIVLSEKYSCPVSGFQLPKIEPRMFSFNSPFGACNTCKGLGKEMFFSTALIVPDTSLSIAQGAI LPWANNDSSFIKDTFNALAQHYNFSLDDPIESLSDKVKNVLFYGSGDEEIKFTYNSEAKSKVVIQPFGGIIPSLEEKYCQ AATQWIKDELLRYQVEGDCRACGGDRLTQESLCVKIANLNISEVAKMRVSEAYDWFTNLEHSLTETHKIIAKLVIKEIKD RISFLKNVGLEYLTIDRSSTTLSGGESQRIRLASQIGSGLSGIMYILDEPSIGLHQSDNKKLLSTLRNLQSLGNSLIVVE HDKETILEADHIIDVGPGAGTEGGKIVAQGGVNDIINVPDSITGQYLSGKKFISIRSNVRIGDNNRSIELKGARSHNLKN VDVKIPLGTLTAVTGVSGSGKSTLIIHTLYKAILKKLEPNTKGYVGEYTDIIGLDNIDKVINIDQSPIGRTPRSNPATYS EVFNYIRDWFSELHEAKARGYKRSRFSFNVNGGRCEACEGCGLTRIEMHFLPDIFINCDVCDGNRYNKETLEIKYNGKSI SDVLNMTVDNAITFFDKAPHIRDKLKTLNEVGLGYIKIGQSATTLSGGEAQRIKLAKELSKRSTGKTLYILDEPTTGLHF EDVNKLLQILHRLVDNGNTVLVIEHNMDVIKSADYIVDVGVGGGDQGGEIVAFGTPQQVSFNDQSITGVYLREYFNK >Mature_956_residues ADCIKIRGAREHNLKNIDIDIPKHKLVVITGLSGSGKSSLAYDTIYAESIRSYLAGWPVRNMQFFSLQNKSDVESISGLS PAIAIDQKTISRNPRSTVGTMTEIYDYLRLLFARIGIPYSPATNSPIQGQTISEMVDIICALPHGTKIDILVPITQVHKD KFNKEISRFKKHGFSKIIIDNHEYEIDNLPILNKYEKHNISVIVDQLVIDNTLRSKITSSLESALQLSDGIIYAKKVTST SMQNNNVQCTFQNQDVIVLSEKYSCPVSGFQLPKIEPRMFSFNSPFGACNTCKGLGKEMFFSTALIVPDTSLSIAQGAIL PWANNDSSFIKDTFNALAQHYNFSLDDPIESLSDKVKNVLFYGSGDEEIKFTYNSEAKSKVVIQPFGGIIPSLEEKYCQA ATQWIKDELLRYQVEGDCRACGGDRLTQESLCVKIANLNISEVAKMRVSEAYDWFTNLEHSLTETHKIIAKLVIKEIKDR ISFLKNVGLEYLTIDRSSTTLSGGESQRIRLASQIGSGLSGIMYILDEPSIGLHQSDNKKLLSTLRNLQSLGNSLIVVEH DKETILEADHIIDVGPGAGTEGGKIVAQGGVNDIINVPDSITGQYLSGKKFISIRSNVRIGDNNRSIELKGARSHNLKNV DVKIPLGTLTAVTGVSGSGKSTLIIHTLYKAILKKLEPNTKGYVGEYTDIIGLDNIDKVINIDQSPIGRTPRSNPATYSE VFNYIRDWFSELHEAKARGYKRSRFSFNVNGGRCEACEGCGLTRIEMHFLPDIFINCDVCDGNRYNKETLEIKYNGKSIS DVLNMTVDNAITFFDKAPHIRDKLKTLNEVGLGYIKIGQSATTLSGGEAQRIKLAKELSKRSTGKTLYILDEPTTGLHFE DVNKLLQILHRLVDNGNTVLVIEHNMDVIKSADYIVDVGVGGGDQGGEIVAFGTPQQVSFNDQSITGVYLREYFNK
Specific function: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion h
COG id: COG0178
COG function: function code L; Excinuclease ATPase subunit
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 2 ABC transporter domains [H]
Homologues:
Organism=Escherichia coli, GI2367343, Length=951, Percent_Identity=49.211356466877, Blast_Score=947, Evalue=0.0,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003439 - InterPro: IPR017871 - InterPro: IPR013815 - InterPro: IPR004602 [H]
Pfam domain/function: PF00005 ABC_tran [H]
EC number: NA
Molecular weight: Translated: 106001; Mature: 105870
Theoretical pI: Translated: 7.06; Mature: 7.06
Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.6 %Cys (Translated Protein) 1.3 %Met (Translated Protein) 2.8 %Cys+Met (Translated Protein) 1.6 %Cys (Mature Protein) 1.2 %Met (Mature Protein) 2.7 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MADCIKIRGAREHNLKNIDIDIPKHKLVVITGLSGSGKSSLAYDTIYAESIRSYLAGWPV CCCCEEECCCCCCCCCEEEEECCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCC RNMQFFSLQNKSDVESISGLSPAIAIDQKTISRNPRSTVGTMTEIYDYLRLLFARIGIPY CCEEEEEECCCCCHHHHCCCCCEEEECHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCC SPATNSPIQGQTISEMVDIICALPHGTKIDILVPITQVHKDKFNKEISRFKKHGFSKIII CCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHCCCEEEEE DNHEYEIDNLPILNKYEKHNISVIVDQLVIDNTLRSKITSSLESALQLSDGIIYAKKVTS CCCEEECCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECC TSMQNNNVQCTFQNQDVIVLSEKYSCPVSGFQLPKIEPRMFSFNSPFGACNTCKGLGKEM CCCCCCCEEEEECCCCEEEEECCCCCCCCCCCCCCCCCCEEECCCCCCCCHHHHHCCHHH FFSTALIVPDTSLSIAQGAILPWANNDSSFIKDTFNALAQHYNFSLDDPIESLSDKVKNV HHEEEEEECCCCCHHHCCCEEECCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHE LFYGSGDEEIKFTYNSEAKSKVVIQPFGGIIPSLEEKYCQAATQWIKDELLRYQVEGDCR EEECCCCCEEEEEECCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHEEEECCCCC ACGGDRLTQESLCVKIANLNISEVAKMRVSEAYDWFTNLEHSLTETHKIIAKLVIKEIKD CCCCCCCCCHHHEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH RISFLKNVGLEYLTIDRSSTTLSGGESQRIRLASQIGSGLSGIMYILDEPSIGLHQSDNK HHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCH KLLSTLRNLQSLGNSLIVVEHDKETILEADHIIDVGPGAGTEGGKIVAQGGVNDIINVPD HHHHHHHHHHHCCCEEEEEECCHHHHHCCCCEEECCCCCCCCCCEEEECCCCCHHCCCCC SITGQYLSGKKFISIRSNVRIGDNNRSIELKGARSHNLKNVDVKIPLGTLTAVTGVSGSG CCCCCCCCCCEEEEEECCEEECCCCCEEEEECCCCCCCCEEEEEEECCHHHHEECCCCCC KSTLIIHTLYKAILKKLEPNTKGYVGEYTDIIGLDNIDKVINIDQSPIGRTPRSNPATYS CCEEHHHHHHHHHHHHCCCCCCCCCCCCHHCCCCCCCHHHEECCCCCCCCCCCCCCCCHH EVFNYIRDWFSELHEAKARGYKRSRFSFNVNGGRCEACEGCGLTRIEMHFLPDIFINCDV HHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCEEEEEEECCCEEEEEEE CDGNRYNKETLEIKYNGKSISDVLNMTVDNAITFFDKAPHIRDKLKTLNEVGLGYIKIGQ ECCCCCCCEEEEEEECCCCHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHCCCCEEEECC SATTLSGGEAQRIKLAKELSKRSTGKTLYILDEPTTGLHFEDVNKLLQILHRLVDNGNTV CCEECCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCEE LVIEHNMDVIKSADYIVDVGVGGGDQGGEIVAFGTPQQVSFNDQSITGVYLREYFNK EEEECCCHHHCCCCEEEEEECCCCCCCCEEEEECCCCEECCCCCCCHHHHHHHHHCC >Mature Secondary Structure ADCIKIRGAREHNLKNIDIDIPKHKLVVITGLSGSGKSSLAYDTIYAESIRSYLAGWPV CCCEEECCCCCCCCCEEEEECCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCC RNMQFFSLQNKSDVESISGLSPAIAIDQKTISRNPRSTVGTMTEIYDYLRLLFARIGIPY CCEEEEEECCCCCHHHHCCCCCEEEECHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCC SPATNSPIQGQTISEMVDIICALPHGTKIDILVPITQVHKDKFNKEISRFKKHGFSKIII CCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHCCCEEEEE DNHEYEIDNLPILNKYEKHNISVIVDQLVIDNTLRSKITSSLESALQLSDGIIYAKKVTS CCCEEECCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECC TSMQNNNVQCTFQNQDVIVLSEKYSCPVSGFQLPKIEPRMFSFNSPFGACNTCKGLGKEM CCCCCCCEEEEECCCCEEEEECCCCCCCCCCCCCCCCCCEEECCCCCCCCHHHHHCCHHH FFSTALIVPDTSLSIAQGAILPWANNDSSFIKDTFNALAQHYNFSLDDPIESLSDKVKNV HHEEEEEECCCCCHHHCCCEEECCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHE LFYGSGDEEIKFTYNSEAKSKVVIQPFGGIIPSLEEKYCQAATQWIKDELLRYQVEGDCR EEECCCCCEEEEEECCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHEEEECCCCC ACGGDRLTQESLCVKIANLNISEVAKMRVSEAYDWFTNLEHSLTETHKIIAKLVIKEIKD CCCCCCCCCHHHEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH RISFLKNVGLEYLTIDRSSTTLSGGESQRIRLASQIGSGLSGIMYILDEPSIGLHQSDNK HHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCH KLLSTLRNLQSLGNSLIVVEHDKETILEADHIIDVGPGAGTEGGKIVAQGGVNDIINVPD HHHHHHHHHHHCCCEEEEEECCHHHHHCCCCEEECCCCCCCCCCEEEECCCCCHHCCCCC SITGQYLSGKKFISIRSNVRIGDNNRSIELKGARSHNLKNVDVKIPLGTLTAVTGVSGSG CCCCCCCCCCEEEEEECCEEECCCCCEEEEECCCCCCCCEEEEEEECCHHHHEECCCCCC KSTLIIHTLYKAILKKLEPNTKGYVGEYTDIIGLDNIDKVINIDQSPIGRTPRSNPATYS CCEEHHHHHHHHHHHHCCCCCCCCCCCCHHCCCCCCCHHHEECCCCCCCCCCCCCCCCHH EVFNYIRDWFSELHEAKARGYKRSRFSFNVNGGRCEACEGCGLTRIEMHFLPDIFINCDV HHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCEEEEEEECCCEEEEEEE CDGNRYNKETLEIKYNGKSISDVLNMTVDNAITFFDKAPHIRDKLKTLNEVGLGYIKIGQ ECCCCCCCEEEEEEECCCCHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHCCCCEEEECC SATTLSGGEAQRIKLAKELSKRSTGKTLYILDEPTTGLHFEDVNKLLQILHRLVDNGNTV CCEECCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCEE LVIEHNMDVIKSADYIVDVGVGGGDQGGEIVAFGTPQQVSFNDQSITGVYLREYFNK EEEECCCHHHCCCCEEEEEECCCCCCCCEEEEECCCCEECCCCCCCHHHHHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: DNA [C]
Specific reaction: Protein + DNA = Protein-DNA [C]
General reaction: Hydrolase; Acting on ester bonds [C]
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 11557893 [H]