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The map label for this gene is fbcH [H]

Identifier: 189184291

GI number: 189184291

Start: 1412734

End: 1413528

Strand: Direct

Name: fbcH [H]

Synonym: OTT_1384

Alternate gene names: 189184291

Gene position: 1412734-1413528 (Clockwise)

Preceding gene: 189184287

Following gene: 189184293

Centisome position: 70.32

GC content: 33.21

Gene sequence:

>795_bases
ATGCAGCAAATATTTAAAAAGATTTCTATATGTTTAATAATATTAGTTATGGAACTTATTGTTGTATTGTCAATACAAGC
TGAAGCTCTTCCTCCAAAAAAATTAGATTGGCCTTTTAATGGAATTTTAGGTCAATTAGATGTTCAAGCAGCTCAGCGAG
GATTTAAAGTATATAAAGAAGTTTGTTCCGCTTGCCATAGCTTAAAATATGTTTCATATAGAAATCTATCAGATATTGGC
TTTTCTGCCGATGAAATTAAAGCTATCGCTAGTGAGTATAATTTTCAGGATGGGCCTAATGACCAAGGGGAAATGTTTGA
GCGGTCTGGATTACCATCAGATCAATTTTACAGTCCATTTCCTAATGATAAGGCTGCTAGAGCAGCGAATAACGGTAGTT
ATCCAGTTGATCTTTCATTAATAATAAAAGCTAGAGAAAAAGGTGCAGACTATGTTTATTCACTCCTTACTGGATATACT
GCACCTCCAGAAGAGTTTAAGTTAGAACATGGACTATACTATAACCCTTATTTTAGCATTCAGAAAATAGCTATGCCACC
ACCTTTAACCGATCACCAAGTTAGTTATAGCGATGGTACTAACAGCAGTGTTGAACAAATGGCTAAAGATATAGTAGTTT
TTTTGCAGTGGGCTGCAGAACCTGAAATGACACATAGAAAGTCTATGGGGTTAAAGGTAATTATATTCCTCATTATTTTT
TCAACTATATTTTATATTGCTAAAGAAAGAGTTTGGTCAAATATCAAAGATAAACATAAAAATACCAATTTATGA

Upstream 100 bases:

>100_bases
AACTACTTGTAATATTATACGGAATAGTATAATAAGCTATATTTGTTAAGTAATAAGAAAAAAAATATTAACAACTATCT
GAAATATATACTTAAAGGTA

Downstream 100 bases:

>100_bases
TAATATTCCTTTCAAATCTATAGTGGTATGATGCTCACTTGAGTTTTATTCTTATCTGATGATACTTTTAACTTGAAAGA
AAATATAGAACTACCACATT

Product: cytochrome c1, heme protein precursor

Products: Q; ferrocytochrome c

Alternate protein names: NA

Number of amino acids: Translated: 264; Mature: 264

Protein sequence:

>264_residues
MQQIFKKISICLIILVMELIVVLSIQAEALPPKKLDWPFNGILGQLDVQAAQRGFKVYKEVCSACHSLKYVSYRNLSDIG
FSADEIKAIASEYNFQDGPNDQGEMFERSGLPSDQFYSPFPNDKAARAANNGSYPVDLSLIIKAREKGADYVYSLLTGYT
APPEEFKLEHGLYYNPYFSIQKIAMPPPLTDHQVSYSDGTNSSVEQMAKDIVVFLQWAAEPEMTHRKSMGLKVIIFLIIF
STIFYIAKERVWSNIKDKHKNTNL

Sequences:

>Translated_264_residues
MQQIFKKISICLIILVMELIVVLSIQAEALPPKKLDWPFNGILGQLDVQAAQRGFKVYKEVCSACHSLKYVSYRNLSDIG
FSADEIKAIASEYNFQDGPNDQGEMFERSGLPSDQFYSPFPNDKAARAANNGSYPVDLSLIIKAREKGADYVYSLLTGYT
APPEEFKLEHGLYYNPYFSIQKIAMPPPLTDHQVSYSDGTNSSVEQMAKDIVVFLQWAAEPEMTHRKSMGLKVIIFLIIF
STIFYIAKERVWSNIKDKHKNTNL
>Mature_264_residues
MQQIFKKISICLIILVMELIVVLSIQAEALPPKKLDWPFNGILGQLDVQAAQRGFKVYKEVCSACHSLKYVSYRNLSDIG
FSADEIKAIASEYNFQDGPNDQGEMFERSGLPSDQFYSPFPNDKAARAANNGSYPVDLSLIIKAREKGADYVYSLLTGYT
APPEEFKLEHGLYYNPYFSIQKIAMPPPLTDHQVSYSDGTNSSVEQMAKDIVVFLQWAAEPEMTHRKSMGLKVIIFLIIF
STIFYIAKERVWSNIKDKHKNTNL

Specific function: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. c1 functions as an electron donor to cytochrome c [H]

COG id: COG2857

COG function: function code C; Cytochrome c1

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cytochrome c domain [H]

Homologues:

Organism=Homo sapiens, GI21359867, Length=229, Percent_Identity=48.0349344978166, Blast_Score=228, Evalue=5e-60,
Organism=Caenorhabditis elegans, GI17506225, Length=244, Percent_Identity=39.7540983606557, Blast_Score=156, Evalue=8e-39,
Organism=Saccharomyces cerevisiae, GI6324639, Length=253, Percent_Identity=41.897233201581, Blast_Score=204, Evalue=2e-53,
Organism=Drosophila melanogaster, GI21358225, Length=246, Percent_Identity=44.7154471544715, Blast_Score=218, Evalue=4e-57,
Organism=Drosophila melanogaster, GI24658292, Length=248, Percent_Identity=45.1612903225806, Blast_Score=210, Evalue=6e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016175
- InterPro:   IPR005798
- InterPro:   IPR005797
- InterPro:   IPR002326
- InterPro:   IPR021157
- InterPro:   IPR009056
- InterPro:   IPR016174 [H]

Pfam domain/function: PF00032 Cytochrom_B_C; PF00033 Cytochrom_B_N; PF02167 Cytochrom_C1 [H]

EC number: 1.10.2.2

Molecular weight: Translated: 29898; Mature: 29898

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS51007 CYTC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQIFKKISICLIILVMELIVVLSIQAEALPPKKLDWPFNGILGQLDVQAAQRGFKVYKE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
VCSACHSLKYVSYRNLSDIGFSADEIKAIASEYNFQDGPNDQGEMFERSGLPSDQFYSPF
HHHHHHHHHHHHHCCCHHCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCCCCCCC
PNDKAARAANNGSYPVDLSLIIKAREKGADYVYSLLTGYTAPPEEFKLEHGLYYNPYFSI
CCCHHHHHCCCCCCCEEHHEEEEEHHCCHHHHHHHHHCCCCCHHHHHHCCCCEECCCCCE
QKIAMPPPLTDHQVSYSDGTNSSVEQMAKDIVVFLQWAAEPEMTHRKSMGLKVIIFLIIF
EEECCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHH
STIFYIAKERVWSNIKDKHKNTNL
HHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MQQIFKKISICLIILVMELIVVLSIQAEALPPKKLDWPFNGILGQLDVQAAQRGFKVYKE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
VCSACHSLKYVSYRNLSDIGFSADEIKAIASEYNFQDGPNDQGEMFERSGLPSDQFYSPF
HHHHHHHHHHHHHCCCHHCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCCCCCCC
PNDKAARAANNGSYPVDLSLIIKAREKGADYVYSLLTGYTAPPEEFKLEHGLYYNPYFSI
CCCHHHHHCCCCCCCEEHHEEEEEHHCCHHHHHHHHHCCCCCHHHHHHCCCCEECCCCCE
QKIAMPPPLTDHQVSYSDGTNSSVEQMAKDIVVFLQWAAEPEMTHRKSMGLKVIIFLIIF
EEECCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHH
STIFYIAKERVWSNIKDKHKNTNL
HHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: QH2; ferricytochrome c

Specific reaction: QH2 + 2 ferricytochrome c = Q + 2 ferrocytochrome c

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2541921; 12597275 [H]