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The map label for this gene is sucC [H]

Identifier: 189184256

GI number: 189184256

Start: 1375564

End: 1376724

Strand: Reverse

Name: sucC [H]

Synonym: OTT_1349

Alternate gene names: 189184256

Gene position: 1376724-1375564 (Counterclockwise)

Preceding gene: 189184257

Following gene: 189184255

Centisome position: 68.53

GC content: 32.39

Gene sequence:

>1161_bases
ATGAATATACATGAATATCAGGCAAAGGAAATTCTTAGTAAATACAATGTTCCAATTCAGCCTGGAATTGCAATACTAAA
GTATGAAGATATTGATTACGCAATTGACTCACTAGCTACTGATACATTTGTTATAAAAGCTCAAATACATGCAGGCGGTA
GAAAAATAGGTGGTGGCATTAAAATATCAAATGATAAAAATGAAGCAAAAAACTTAGCAAAGAATATGTGGGGAATGAAT
TTAGTAACTCCACAAACTGGTCCTAAAGGCCAAAAAGTGCAAAGAATATATATTGAATCTGCTGCTAAGATCAAGCTAGA
GCTATACTTAGGAGCAGTGATAGATCGGTCAAATCATTGTATTACTTTTATGGCATCTTCTGAAGGAGGAATTAATATTG
AAGAAGTAGCTCATACTAATCCAGACAAAATCATCAAAGTTAAGATAAATATTTTAACTGGTATACAACCATTTCATAGT
CGTAAAATTATTTTTCAGCTTGGACTTACTGGAGATTTAGCAAAACAAATGGCTAAAATAATGAGTGCAGTTTATAGCAT
GCTAATTAATACTGATGCTACTCAAGTTGAAATTAATCCTCTAATTATTACTTTGGACGATAAACTAATAGCACTTGATG
CTAAAATAAACTTTGACGATAGTGCTTTGTTTAGGCAGCCATTAATTCAAGAAATGCGTGATGAAGATGAGGAAGACCAG
CTAGAATTAAGAGCTACAAAAGCTGATTTAAGTTATGTTAGAATGAATGGCAATATTGGATGTATGGTTAATGGGGCTGG
TCTAGCAATGGCCACTATGGATATTATTAAGCTTTATGGTGCAGAACCAGCTAATTTTCTCGATGTTGGAGGAAGTGCTG
ATAAGGAAAGAGTAGCAGAGGCCTTAAAAATTATATCATCTGATCAAAATGTTAAAGGAATATTAATTAACATTTTTGGA
GGAATTATGCGATGTGATATTATTGCTGAAGGAGTATTAGCAGCAGCTAAGGAAATAAATTTATCTATACCTTTGGTTGT
TAGATTAGCTGGTACTAACTTTGAACTTGGTAAAGAAATATTAAGTAATTCAAAATTACAAATAGTAGCAGCTAATGATT
TAGATGATGCTGCTAGAAAAATAGTTGAAGCAGTTAGTTAA

Upstream 100 bases:

>100_bases
CCGTTAGTTCCAAAATAATAAATATTGCAAATTATATTTTTTAAGTTACATTCAAGTAATAAATTATATTTAACACTAAA
ATGATTTATAGGATTAAGTA

Downstream 100 bases:

>100_bases
ATAAGGAAAAATGTATGTCAGTATTGGTTGATAGAAATACTAAAGTTATATGTCAAGGTATAACAGGCGCTCAAGGAACT
TTTCATACTGAGCAAGCATT

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta [H]

Number of amino acids: Translated: 386; Mature: 386

Protein sequence:

>386_residues
MNIHEYQAKEILSKYNVPIQPGIAILKYEDIDYAIDSLATDTFVIKAQIHAGGRKIGGGIKISNDKNEAKNLAKNMWGMN
LVTPQTGPKGQKVQRIYIESAAKIKLELYLGAVIDRSNHCITFMASSEGGINIEEVAHTNPDKIIKVKINILTGIQPFHS
RKIIFQLGLTGDLAKQMAKIMSAVYSMLINTDATQVEINPLIITLDDKLIALDAKINFDDSALFRQPLIQEMRDEDEEDQ
LELRATKADLSYVRMNGNIGCMVNGAGLAMATMDIIKLYGAEPANFLDVGGSADKERVAEALKIISSDQNVKGILINIFG
GIMRCDIIAEGVLAAAKEINLSIPLVVRLAGTNFELGKEILSNSKLQIVAANDLDDAARKIVEAVS

Sequences:

>Translated_386_residues
MNIHEYQAKEILSKYNVPIQPGIAILKYEDIDYAIDSLATDTFVIKAQIHAGGRKIGGGIKISNDKNEAKNLAKNMWGMN
LVTPQTGPKGQKVQRIYIESAAKIKLELYLGAVIDRSNHCITFMASSEGGINIEEVAHTNPDKIIKVKINILTGIQPFHS
RKIIFQLGLTGDLAKQMAKIMSAVYSMLINTDATQVEINPLIITLDDKLIALDAKINFDDSALFRQPLIQEMRDEDEEDQ
LELRATKADLSYVRMNGNIGCMVNGAGLAMATMDIIKLYGAEPANFLDVGGSADKERVAEALKIISSDQNVKGILINIFG
GIMRCDIIAEGVLAAAKEINLSIPLVVRLAGTNFELGKEILSNSKLQIVAANDLDDAARKIVEAVS
>Mature_386_residues
MNIHEYQAKEILSKYNVPIQPGIAILKYEDIDYAIDSLATDTFVIKAQIHAGGRKIGGGIKISNDKNEAKNLAKNMWGMN
LVTPQTGPKGQKVQRIYIESAAKIKLELYLGAVIDRSNHCITFMASSEGGINIEEVAHTNPDKIIKVKINILTGIQPFHS
RKIIFQLGLTGDLAKQMAKIMSAVYSMLINTDATQVEINPLIITLDDKLIALDAKINFDDSALFRQPLIQEMRDEDEEDQ
LELRATKADLSYVRMNGNIGCMVNGAGLAMATMDIIKLYGAEPANFLDVGGSADKERVAEALKIISSDQNVKGILINIFG
GIMRCDIIAEGVLAAAKEINLSIPLVVRLAGTNFELGKEILSNSKLQIVAANDLDDAARKIVEAVS

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

Organism=Homo sapiens, GI11321583, Length=391, Percent_Identity=42.9667519181586, Blast_Score=317, Evalue=1e-86,
Organism=Homo sapiens, GI157779135, Length=383, Percent_Identity=43.3420365535248, Blast_Score=309, Evalue=3e-84,
Organism=Homo sapiens, GI294862256, Length=362, Percent_Identity=43.0939226519337, Blast_Score=291, Evalue=7e-79,
Organism=Escherichia coli, GI1786948, Length=385, Percent_Identity=50.3896103896104, Blast_Score=389, Evalue=1e-109,
Organism=Caenorhabditis elegans, GI17567829, Length=393, Percent_Identity=43.2569974554707, Blast_Score=327, Evalue=5e-90,
Organism=Caenorhabditis elegans, GI17539378, Length=394, Percent_Identity=43.4010152284264, Blast_Score=315, Evalue=3e-86,
Organism=Saccharomyces cerevisiae, GI6321683, Length=393, Percent_Identity=42.4936386768448, Blast_Score=316, Evalue=4e-87,
Organism=Drosophila melanogaster, GI21356231, Length=395, Percent_Identity=44.5569620253165, Blast_Score=311, Evalue=4e-85,
Organism=Drosophila melanogaster, GI161078106, Length=387, Percent_Identity=43.9276485788114, Blast_Score=310, Evalue=1e-84,
Organism=Drosophila melanogaster, GI24645208, Length=387, Percent_Identity=43.9276485788114, Blast_Score=310, Evalue=1e-84,
Organism=Drosophila melanogaster, GI281361397, Length=388, Percent_Identity=43.8144329896907, Blast_Score=308, Evalue=5e-84,
Organism=Drosophila melanogaster, GI281361395, Length=388, Percent_Identity=43.8144329896907, Blast_Score=308, Evalue=5e-84,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102 [H]

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 42123; Mature: 42123

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIHEYQAKEILSKYNVPIQPGIAILKYEDIDYAIDSLATDTFVIKAQIHAGGRKIGGGI
CCCHHHHHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHCCCEEEEEEEEECCCEEECCCE
KISNDKNEAKNLAKNMWGMNLVTPQTGPKGQKVQRIYIESAAKIKLELYLGAVIDRSNHC
EECCCHHHHHHHHHHHCCCEEECCCCCCCCCCEEEEEEECCCEEEEEEEEEEEEECCCCE
ITFMASSEGGINIEEVAHTNPDKIIKVKINILTGIQPFHSRKIIFQLGLTGDLAKQMAKI
EEEEECCCCCCCHHHHCCCCCCCEEEEEEEEEECCCCCCCCEEEEEECCCHHHHHHHHHH
MSAVYSMLINTDATQVEINPLIITLDDKLIALDAKINFDDSALFRQPLIQEMRDEDEEDQ
HHHHHHHHHCCCCCEEEEEEEEEEECCEEEEEEEEECCCCHHHHHHHHHHHHHCCCCCCC
LELRATKADLSYVRMNGNIGCMVNGAGLAMATMDIIKLYGAEPANFLDVGGSADKERVAE
EEEEEEECCEEEEEECCCEEEEEECCCHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHH
ALKIISSDQNVKGILINIFGGIMRCDIIAEGVLAAAKEINLSIPLVVRLAGTNFELGKEI
HHHHHCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHH
LSNSKLQIVAANDLDDAARKIVEAVS
HCCCCEEEEEECCCCHHHHHHHHHCC
>Mature Secondary Structure
MNIHEYQAKEILSKYNVPIQPGIAILKYEDIDYAIDSLATDTFVIKAQIHAGGRKIGGGI
CCCHHHHHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHCCCEEEEEEEEECCCEEECCCE
KISNDKNEAKNLAKNMWGMNLVTPQTGPKGQKVQRIYIESAAKIKLELYLGAVIDRSNHC
EECCCHHHHHHHHHHHCCCEEECCCCCCCCCCEEEEEEECCCEEEEEEEEEEEEECCCCE
ITFMASSEGGINIEEVAHTNPDKIIKVKINILTGIQPFHSRKIIFQLGLTGDLAKQMAKI
EEEEECCCCCCCHHHHCCCCCCCEEEEEEEEEECCCCCCCCEEEEEECCCHHHHHHHHHH
MSAVYSMLINTDATQVEINPLIITLDDKLIALDAKINFDDSALFRQPLIQEMRDEDEEDQ
HHHHHHHHHCCCCCEEEEEEEEEEECCEEEEEEEEECCCCHHHHHHHHHHHHHCCCCCCC
LELRATKADLSYVRMNGNIGCMVNGAGLAMATMDIIKLYGAEPANFLDVGGSADKERVAE
EEEEEEECCEEEEEECCCEEEEEECCCHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHH
ALKIISSDQNVKGILINIFGGIMRCDIIAEGVLAAAKEINLSIPLVVRLAGTNFELGKEI
HHHHHCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHH
LSNSKLQIVAANDLDDAARKIVEAVS
HCCCCEEEEEECCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA