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The map label for this gene is sucD [H]

Identifier: 189184255

GI number: 189184255

Start: 1374671

End: 1375549

Strand: Reverse

Name: sucD [H]

Synonym: OTT_1348

Alternate gene names: 189184255

Gene position: 1375549-1374671 (Counterclockwise)

Preceding gene: 189184256

Following gene: 189184254

Centisome position: 68.47

GC content: 36.29

Gene sequence:

>879_bases
ATGTCAGTATTGGTTGATAGAAATACTAAAGTTATATGTCAAGGTATAACAGGCGCTCAAGGAACTTTTCATACTGAGCA
AGCATTAAAATATGGAACTAAAATGGTTGGAGGAGTTACTCCAGGTAAAGGAGGCCAAACTATCTTGAATTTACCAGTAT
ACAATTCTGTTGATGAGGCTGTTCAAAAAACCGGAGCTACGGCTAGTGTAATATATGTTCCTCCAGCTTTTGCTGCTGAC
TCTATATTTGAAGCTATTGATGCTGGTATAGAATTGTTAGTTTGTATTACAGAAGGTATTCCAGTGCTTGATATGTTAAA
AATCAAGCAAGTATTGAAAGGAAGTAAAACTAGGTTAATAGGACCAAATTGTCCAGGGATTATTACTCCAGAGCAATGTA
AAATTGGAATTATGCCAGGACATATTCATAAAGCAGGTTCAATAGGAATTATCTCTCGTTCCGGAACTTTAACTTACGAG
GCAGTAGCTCAAACTACAGAAGTTGGATTAGGTCAATCAACATGTATTGGTATTGGTGGAGATCCAATTAATGGTACTAG
TTTTGTTGATTGTTTAGAATTATTTCTAGCAGATGGTGATACCAAAGCAATAATTATTATTGGAGAGATAGGTGGCAGCG
CAGAAGAAGAAGCAGCAGATTTCTTAAAATCATCTAGAATTAAGAAACCAATAGTAGGATTTATAGCTGGAGTAACTGCT
CCTCCTGGCAAAAGAATGGGACATGCTGGAGCAATAATAGATGGAGAAAAAGGAGCTGCCAGCAGTAAATTAGAAGCATT
AAAAAGCGCTGGAGTTTGTATTGCAGAATCTCCTGCAAAAATCGGGCAAACAATGTATAATTTATTACATAATCTCTAA

Upstream 100 bases:

>100_bases
AAATATTAAGTAATTCAAAATTACAAATAGTAGCAGCTAATGATTTAGATGATGCTGCTAGAAAAATAGTTGAAGCAGTT
AGTTAAATAAGGAAAAATGT

Downstream 100 bases:

>100_bases
ATATTGAATTTAAAATTTAATAACTAAAATATTTTTTAGTAGTTTTTTGAGACAAAACTACTCCTATAATGAGCGGAATG
ATGGAAAAAGCTAGCTTTCA

Product: succinyl-CoA synthetase alpha chain

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit alpha; SCS-alpha [H]

Number of amino acids: Translated: 292; Mature: 291

Protein sequence:

>292_residues
MSVLVDRNTKVICQGITGAQGTFHTEQALKYGTKMVGGVTPGKGGQTILNLPVYNSVDEAVQKTGATASVIYVPPAFAAD
SIFEAIDAGIELLVCITEGIPVLDMLKIKQVLKGSKTRLIGPNCPGIITPEQCKIGIMPGHIHKAGSIGIISRSGTLTYE
AVAQTTEVGLGQSTCIGIGGDPINGTSFVDCLELFLADGDTKAIIIIGEIGGSAEEEAADFLKSSRIKKPIVGFIAGVTA
PPGKRMGHAGAIIDGEKGAASSKLEALKSAGVCIAESPAKIGQTMYNLLHNL

Sequences:

>Translated_292_residues
MSVLVDRNTKVICQGITGAQGTFHTEQALKYGTKMVGGVTPGKGGQTILNLPVYNSVDEAVQKTGATASVIYVPPAFAAD
SIFEAIDAGIELLVCITEGIPVLDMLKIKQVLKGSKTRLIGPNCPGIITPEQCKIGIMPGHIHKAGSIGIISRSGTLTYE
AVAQTTEVGLGQSTCIGIGGDPINGTSFVDCLELFLADGDTKAIIIIGEIGGSAEEEAADFLKSSRIKKPIVGFIAGVTA
PPGKRMGHAGAIIDGEKGAASSKLEALKSAGVCIAESPAKIGQTMYNLLHNL
>Mature_291_residues
SVLVDRNTKVICQGITGAQGTFHTEQALKYGTKMVGGVTPGKGGQTILNLPVYNSVDEAVQKTGATASVIYVPPAFAADS
IFEAIDAGIELLVCITEGIPVLDMLKIKQVLKGSKTRLIGPNCPGIITPEQCKIGIMPGHIHKAGSIGIISRSGTLTYEA
VAQTTEVGLGQSTCIGIGGDPINGTSFVDCLELFLADGDTKAIIIIGEIGGSAEEEAADFLKSSRIKKPIVGFIAGVTAP
PGKRMGHAGAIIDGEKGAASSKLEALKSAGVCIAESPAKIGQTMYNLLHNL

Specific function: Unknown

COG id: COG0074

COG function: function code C; Succinyl-CoA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the succinate/malate CoA ligase alpha subunit family [H]

Homologues:

Organism=Homo sapiens, GI109452591, Length=288, Percent_Identity=69.0972222222222, Blast_Score=353, Evalue=7e-98,
Organism=Homo sapiens, GI38569421, Length=318, Percent_Identity=27.9874213836478, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI38569423, Length=318, Percent_Identity=27.9874213836478, Blast_Score=93, Evalue=4e-19,
Organism=Escherichia coli, GI1786949, Length=289, Percent_Identity=67.4740484429066, Blast_Score=393, Evalue=1e-111,
Organism=Caenorhabditis elegans, GI17553126, Length=292, Percent_Identity=64.3835616438356, Blast_Score=357, Evalue=6e-99,
Organism=Caenorhabditis elegans, GI17550194, Length=288, Percent_Identity=64.2361111111111, Blast_Score=356, Evalue=6e-99,
Organism=Caenorhabditis elegans, GI17557344, Length=263, Percent_Identity=29.277566539924, Blast_Score=99, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17551266, Length=265, Percent_Identity=28.3018867924528, Blast_Score=93, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6324716, Length=294, Percent_Identity=54.7619047619048, Blast_Score=297, Evalue=1e-81,
Organism=Drosophila melanogaster, GI21356559, Length=295, Percent_Identity=58.9830508474576, Blast_Score=349, Evalue=1e-96,
Organism=Drosophila melanogaster, GI28574296, Length=289, Percent_Identity=64.7058823529412, Blast_Score=342, Evalue=2e-94,
Organism=Drosophila melanogaster, GI281363477, Length=264, Percent_Identity=28.4090909090909, Blast_Score=98, Evalue=6e-21,
Organism=Drosophila melanogaster, GI281363475, Length=264, Percent_Identity=28.4090909090909, Blast_Score=98, Evalue=7e-21,
Organism=Drosophila melanogaster, GI281363473, Length=264, Percent_Identity=28.4090909090909, Blast_Score=98, Evalue=7e-21,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017440
- InterPro:   IPR003781
- InterPro:   IPR005810
- InterPro:   IPR005811
- InterPro:   IPR016040
- InterPro:   IPR016102 [H]

Pfam domain/function: PF02629 CoA_binding; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 30101; Mature: 29970

Theoretical pI: Translated: 6.66; Mature: 6.66

Prosite motif: PS01216 SUCCINYL_COA_LIG_1 ; PS00399 SUCCINYL_COA_LIG_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVLVDRNTKVICQGITGAQGTFHTEQALKYGTKMVGGVTPGKGGQTILNLPVYNSVDEA
CCEEEECCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCHHHH
VQKTGATASVIYVPPAFAADSIFEAIDAGIELLVCITEGIPVLDMLKIKQVLKGSKTRLI
HHHCCCCEEEEEECCCHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHCCCCCEEE
GPNCPGIITPEQCKIGIMPGHIHKAGSIGIISRSGTLTYEAVAQTTEVGLGQSTCIGIGG
CCCCCCCCCCCCCEEECCCCCCCCCCCEEEEECCCCEEHHHHHHHHHCCCCCCEEEECCC
DPINGTSFVDCLELFLADGDTKAIIIIGEIGGSAEEEAADFLKSSRIKKPIVGFIAGVTA
CCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHCCCC
PPGKRMGHAGAIIDGEKGAASSKLEALKSAGVCIAESPAKIGQTMYNLLHNL
CCCCCCCCCCCEEECCCCCCHHHHHHHHHCCCEEECCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SVLVDRNTKVICQGITGAQGTFHTEQALKYGTKMVGGVTPGKGGQTILNLPVYNSVDEA
CEEEECCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCHHHH
VQKTGATASVIYVPPAFAADSIFEAIDAGIELLVCITEGIPVLDMLKIKQVLKGSKTRLI
HHHCCCCEEEEEECCCHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHCCCCCEEE
GPNCPGIITPEQCKIGIMPGHIHKAGSIGIISRSGTLTYEAVAQTTEVGLGQSTCIGIGG
CCCCCCCCCCCCCEEECCCCCCCCCCCEEEEECCCCEEHHHHHHHHHCCCCCCEEEECCC
DPINGTSFVDCLELFLADGDTKAIIIIGEIGGSAEEEAADFLKSSRIKKPIVGFIAGVTA
CCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHCCCC
PPGKRMGHAGAIIDGEKGAASSKLEALKSAGVCIAESPAKIGQTMYNLLHNL
CCCCCCCCCCCEEECCCCCCHHHHHHHHHCCCEEECCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]