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The map label for this gene is ppiD [H]

Identifier: 189184244

GI number: 189184244

Start: 1361244

End: 1362797

Strand: Reverse

Name: ppiD [H]

Synonym: OTT_1337

Alternate gene names: 189184244

Gene position: 1362797-1361244 (Counterclockwise)

Preceding gene: 189184247

Following gene: 189184240

Centisome position: 67.84

GC content: 27.28

Gene sequence:

>1554_bases
GTGTTAAATAAATTAAGAACAGCCTCACATAGCATTGCGTTTAAAATCTTAATATTAATTTTAATATTAGCCTCTGTTTT
CTGGAGCATAGGTACAATGTTTCATTCAAGTAACAATAGCTCTGACATCGTAACTTTTACTAAGGCTAAAAATATTACTA
AAAGTGAGTTTATGCAAGCACTAAAACTAGCAATGCATCAAATACCACAAAATTCTGATCAAAATCTTCTTACACAAAAT
AACATAAGAGAACTAGTATTAAGCAATTTAATAAGTACTCACGTATTAGAACAATTAGCGCATGAATATAATTTAACTTT
AAGTACAGCAGCAGTTTTTAAATTTATTCAAAATTCAAAAGCTTTTAATAATAACCAGAATTTTGACATCAATATTTTTA
GAAATATACTCAAAAATTTACATATCAGTGAACCACAATATTTTGATCAAGCTGCAAAACAGCAATTATCAGAAATATTA
TTACGTCAGTTTATTAATAATAACTATGTTCCAAGTATACTAACCAAAAATATTATTAATTTATCTGCTGAAACACGAAA
TATTCAGCTAGTAAGTATTGATTTGCAAAATGAACAGTTACAATCAACTCTTGATTCTCCATCAAGCGAGCAATTACAAG
AATTTTACAATAATAACCAATCTAAGTTTGAAAAACCAGAGCAGCGTCATATTAGCTATATAGTACTTGACAACAATTAT
TTTAAAAACAAAGTTATTGTTGACAACAAATCACTAGAAGAATTCTATCGCACTCATAGTGATCAATTTTCAGAAAAAAA
TAGCTTTACTAAAAATATTGCTGAGGTTAGGGAAAAATATGTTAATCATCAGGTTGATAAATTATTTAATGATACTATAA
CACTATTAGAAGATGAAGTAGCATCAGGCAGTAATTCATCAGAAATAGCTAAAATGCTAAATGTAAAGCTACTAACATTA
AATAATGTAACTAAGCAAAAATTAGCCAATAATAAAATTTTGAGTAATGTTACTGATGCTATTTTTGCATTAGAAGAGCA
TGAAACATCATATCCGCTTGATGTTTCATCAAAGATGCTGATTATAGTCAGTATTCAAAAAATCATTCCTACTGCTGTTG
AAAAATTTGATAATGTACTTAATCAAGTCCAAGAAGAATGGAAAAAAAATACTATAAGAGAACGCAATATTGAACTTTTA
AATAAGTTTCAGCAAACGACTAACGCTGATAATTTTATTGCTGATGCTAAGAAATATAAACTAACTGTAAAGCCAAATGT
AATAGTAACTAGATTAAATAACAATACTGTAGAACTTCCTAAAGAATTTGTTGAGCAATTGCTAACTTTAAAAAAACGTG
AAGTTTCAAATGTTTACATCTCTACATCAAACCAACATGCTTATGTAGCACTCATATCGGCAATTACAACAGATCGTGAC
TTAACAACAAAATTTTTGTCATTAACAGAAGATATTAAAGGTAGCTTTAAAAATTTAGTATATCATGAGTTAGTTACATA
CCTATATAATTTATATAAAGGAGAAGTTAAATAA

Upstream 100 bases:

>100_bases
AGAAACTACAATTGATTCCATACTTTAAGATAAAAAATTACTTGCAGATTTATAATACTTAAATATTGTATTGGTATATA
CATATATTATACAAGTTACA

Downstream 100 bases:

>100_bases
TTTCTCCTTTTATAGGCTATATTAATTTAATTAGTATCACTATCATAACCTCCGCATGCACCAGTCACATCAACTGAAAA
TTCTTCACAGCTGCATTGAT

Product: peptidyl-prolyl cis-trans isomerse D

Products: NA

Alternate protein names: PPIase D; Rotamase D [H]

Number of amino acids: Translated: 517; Mature: 517

Protein sequence:

>517_residues
MLNKLRTASHSIAFKILILILILASVFWSIGTMFHSSNNSSDIVTFTKAKNITKSEFMQALKLAMHQIPQNSDQNLLTQN
NIRELVLSNLISTHVLEQLAHEYNLTLSTAAVFKFIQNSKAFNNNQNFDINIFRNILKNLHISEPQYFDQAAKQQLSEIL
LRQFINNNYVPSILTKNIINLSAETRNIQLVSIDLQNEQLQSTLDSPSSEQLQEFYNNNQSKFEKPEQRHISYIVLDNNY
FKNKVIVDNKSLEEFYRTHSDQFSEKNSFTKNIAEVREKYVNHQVDKLFNDTITLLEDEVASGSNSSEIAKMLNVKLLTL
NNVTKQKLANNKILSNVTDAIFALEEHETSYPLDVSSKMLIIVSIQKIIPTAVEKFDNVLNQVQEEWKKNTIRERNIELL
NKFQQTTNADNFIADAKKYKLTVKPNVIVTRLNNNTVELPKEFVEQLLTLKKREVSNVYISTSNQHAYVALISAITTDRD
LTTKFLSLTEDIKGSFKNLVYHELVTYLYNLYKGEVK

Sequences:

>Translated_517_residues
MLNKLRTASHSIAFKILILILILASVFWSIGTMFHSSNNSSDIVTFTKAKNITKSEFMQALKLAMHQIPQNSDQNLLTQN
NIRELVLSNLISTHVLEQLAHEYNLTLSTAAVFKFIQNSKAFNNNQNFDINIFRNILKNLHISEPQYFDQAAKQQLSEIL
LRQFINNNYVPSILTKNIINLSAETRNIQLVSIDLQNEQLQSTLDSPSSEQLQEFYNNNQSKFEKPEQRHISYIVLDNNY
FKNKVIVDNKSLEEFYRTHSDQFSEKNSFTKNIAEVREKYVNHQVDKLFNDTITLLEDEVASGSNSSEIAKMLNVKLLTL
NNVTKQKLANNKILSNVTDAIFALEEHETSYPLDVSSKMLIIVSIQKIIPTAVEKFDNVLNQVQEEWKKNTIRERNIELL
NKFQQTTNADNFIADAKKYKLTVKPNVIVTRLNNNTVELPKEFVEQLLTLKKREVSNVYISTSNQHAYVALISAITTDRD
LTTKFLSLTEDIKGSFKNLVYHELVTYLYNLYKGEVK
>Mature_517_residues
MLNKLRTASHSIAFKILILILILASVFWSIGTMFHSSNNSSDIVTFTKAKNITKSEFMQALKLAMHQIPQNSDQNLLTQN
NIRELVLSNLISTHVLEQLAHEYNLTLSTAAVFKFIQNSKAFNNNQNFDINIFRNILKNLHISEPQYFDQAAKQQLSEIL
LRQFINNNYVPSILTKNIINLSAETRNIQLVSIDLQNEQLQSTLDSPSSEQLQEFYNNNQSKFEKPEQRHISYIVLDNNY
FKNKVIVDNKSLEEFYRTHSDQFSEKNSFTKNIAEVREKYVNHQVDKLFNDTITLLEDEVASGSNSSEIAKMLNVKLLTL
NNVTKQKLANNKILSNVTDAIFALEEHETSYPLDVSSKMLIIVSIQKIIPTAVEKFDNVLNQVQEEWKKNTIRERNIELL
NKFQQTTNADNFIADAKKYKLTVKPNVIVTRLNNNTVELPKEFVEQLLTLKKREVSNVYISTSNQHAYVALISAITTDRD
LTTKFLSLTEDIKGSFKNLVYHELVTYLYNLYKGEVK

Specific function: PPIases accelerate the folding of proteins. Seems to be involved in the folding of outer membrane proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1786645, Length=394, Percent_Identity=24.1116751269036, Blast_Score=87, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 59575; Mature: 59575

Theoretical pI: Translated: 8.53; Mature: 8.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNKLRTASHSIAFKILILILILASVFWSIGTMFHSSNNSSDIVTFTKAKNITKSEFMQA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHHH
LKLAMHQIPQNSDQNLLTQNNIRELVLSNLISTHVLEQLAHEYNLTLSTAAVFKFIQNSK
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCC
AFNNNQNFDINIFRNILKNLHISEPQYFDQAAKQQLSEILLRQFINNNYVPSILTKNIIN
CCCCCCCEEHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
LSAETRNIQLVSIDLQNEQLQSTLDSPSSEQLQEFYNNNQSKFEKPEQRHISYIVLDNNY
CCCCCCEEEEEEEECCHHHHHHHHCCCCHHHHHHHHCCCCHHCCCCHHHCEEEEEEECCC
FKNKVIVDNKSLEEFYRTHSDQFSEKNSFTKNIAEVREKYVNHQVDKLFNDTITLLEDEV
CCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASGSNSSEIAKMLNVKLLTLNNVTKQKLANNKILSNVTDAIFALEEHETSYPLDVSSKML
CCCCCHHHHHHHHHHEEEEECCHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEE
IIVSIQKIIPTAVEKFDNVLNQVQEEWKKNTIRERNIELLNKFQQTTNADNFIADAKKYK
EEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHEE
LTVKPNVIVTRLNNNTVELPKEFVEQLLTLKKREVSNVYISTSNQHAYVALISAITTDRD
EEECCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCEEEEECCCCCHHHHHHHHHHCCHH
LTTKFLSLTEDIKGSFKNLVYHELVTYLYNLYKGEVK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLNKLRTASHSIAFKILILILILASVFWSIGTMFHSSNNSSDIVTFTKAKNITKSEFMQA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHHH
LKLAMHQIPQNSDQNLLTQNNIRELVLSNLISTHVLEQLAHEYNLTLSTAAVFKFIQNSK
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCC
AFNNNQNFDINIFRNILKNLHISEPQYFDQAAKQQLSEILLRQFINNNYVPSILTKNIIN
CCCCCCCEEHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
LSAETRNIQLVSIDLQNEQLQSTLDSPSSEQLQEFYNNNQSKFEKPEQRHISYIVLDNNY
CCCCCCEEEEEEEECCHHHHHHHHCCCCHHHHHHHHCCCCHHCCCCHHHCEEEEEEECCC
FKNKVIVDNKSLEEFYRTHSDQFSEKNSFTKNIAEVREKYVNHQVDKLFNDTITLLEDEV
CCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASGSNSSEIAKMLNVKLLTLNNVTKQKLANNKILSNVTDAIFALEEHETSYPLDVSSKML
CCCCCHHHHHHHHHHEEEEECCHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEE
IIVSIQKIIPTAVEKFDNVLNQVQEEWKKNTIRERNIELLNKFQQTTNADNFIADAKKYK
EEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHEE
LTVKPNVIVTRLNNNTVELPKEFVEQLLTLKKREVSNVYISTSNQHAYVALISAITTDRD
EEECCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCEEEEECCCCCHHHHHHHHHHCCHH
LTTKFLSLTEDIKGSFKNLVYHELVTYLYNLYKGEVK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]