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The map label for this gene is aatA [H]

Identifier: 189184077

GI number: 189184077

Start: 1197282

End: 1198484

Strand: Reverse

Name: aatA [H]

Synonym: OTT_1170

Alternate gene names: 189184077

Gene position: 1198484-1197282 (Counterclockwise)

Preceding gene: 189184086

Following gene: 189184073

Centisome position: 59.66

GC content: 32.0

Gene sequence:

>1203_bases
ATGTCACTTATTACTCATAGAATCAATCGTATAAAAAGTTCTCCAACATTGGCAGTTGCAAAAAAGGCAGCTGAACTTCA
GCAACAAGGCAAAAATATAATTTCCTTAAGTGTAGGCGAGTTAAATTTTGATACTCATGATAACATTAAAGCTCAAGCTA
TTGAAGCTATAAATCGCGGTATGACAAAATACACTAATGTTGATGGTATGCCAGAATTAAAACAAGCAGTAAAAAACAAG
TTTAAGGTTGAAAATAATCTTGATTATCAACTAGATGAGCTAATAGTTAGCTCTGGAGCTAAGCAAGTTATTTTTAATGC
TCTATTAGCTACTTTGGATATAGGAGATGAAGTTATTATTCCAACACCATACTGGGTGTCATATCCTGATATTGTATCTC
TAACTGGCGCTACTAGTAAATTTATTTATTGTCATGAAAGCTCTAATTTTAAAATTACTCCAGCACAACTTAGTAATGCG
ATTACTGATAAAACTAAGTGGCTATTACTAAATTCACCTAATAATCCTACTGGCGCCATTTATACAATTGAAGAGTTAAA
ATTATTAGCAGAAATACTTAGCATACATAAAAATATACACATAATGTGTGATGATATTTATGAGCATATTATATTTGATA
ACAATAAATTTTATACTTTAGCAGCTATAGCTCCAAGTTTAAAGGAAAGAATATTTATTGTTAATGGAGTTTCAAAGGCA
TATGCAATGACTGGATGGCGCATTGGTTATGGAGCTGGCAATAGCGAAATTATTAAAGCAATGATTAAAATTCAGTCTCA
TAGTACTTCTAATCCTTGTTCTATTAGCCAAGTTGCAGCAATTGAAGCATTAACAGGCAGTCAGAGTCATATTCAAGATA
ATATTACAATTTTACAAAGAAACCGAGATTTAGCCTTTAATATTCTCAATAATACCATTGGGCTTAAGTGCTATAAACCA
ACAGGAACATTTTATCTTTTTGTTTCTTGTCAAGAACTGTTACATAAAGCTACCTCTACTGGTCAAAAAATAAACACAAG
TAATGACTTTGCTTGCTACTTACTCGAAGAGGCAGAAGTATCAGTAGTACCTGGTGAAGCTTTTGGTATAAATGGATACT
TTAGATTATCTTATGCAGTAGATGCAGCAGAACTAAATATTGCATGTCTGCAAATCAAAAAAGCTTGCGAAAAGCTGATA
TAG

Upstream 100 bases:

>100_bases
TTTGATTTAAATAATGTATACTTAATATAATAATTATATTTGGTAGCATATGTAATTTAATAATTTATAGCTTTAAATAT
TACAATTATGTAGTTAATTT

Downstream 100 bases:

>100_bases
TAAGTTTGTCATATAATTTACATAAGTAGACAAAACAGAATCTACAAAATCTTAACTTGATATTGTGAAGTATTCCAAGA
ACTATATGCCTACAAATATA

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 400; Mature: 399

Protein sequence:

>400_residues
MSLITHRINRIKSSPTLAVAKKAAELQQQGKNIISLSVGELNFDTHDNIKAQAIEAINRGMTKYTNVDGMPELKQAVKNK
FKVENNLDYQLDELIVSSGAKQVIFNALLATLDIGDEVIIPTPYWVSYPDIVSLTGATSKFIYCHESSNFKITPAQLSNA
ITDKTKWLLLNSPNNPTGAIYTIEELKLLAEILSIHKNIHIMCDDIYEHIIFDNNKFYTLAAIAPSLKERIFIVNGVSKA
YAMTGWRIGYGAGNSEIIKAMIKIQSHSTSNPCSISQVAAIEALTGSQSHIQDNITILQRNRDLAFNILNNTIGLKCYKP
TGTFYLFVSCQELLHKATSTGQKINTSNDFACYLLEEAEVSVVPGEAFGINGYFRLSYAVDAAELNIACLQIKKACEKLI

Sequences:

>Translated_400_residues
MSLITHRINRIKSSPTLAVAKKAAELQQQGKNIISLSVGELNFDTHDNIKAQAIEAINRGMTKYTNVDGMPELKQAVKNK
FKVENNLDYQLDELIVSSGAKQVIFNALLATLDIGDEVIIPTPYWVSYPDIVSLTGATSKFIYCHESSNFKITPAQLSNA
ITDKTKWLLLNSPNNPTGAIYTIEELKLLAEILSIHKNIHIMCDDIYEHIIFDNNKFYTLAAIAPSLKERIFIVNGVSKA
YAMTGWRIGYGAGNSEIIKAMIKIQSHSTSNPCSISQVAAIEALTGSQSHIQDNITILQRNRDLAFNILNNTIGLKCYKP
TGTFYLFVSCQELLHKATSTGQKINTSNDFACYLLEEAEVSVVPGEAFGINGYFRLSYAVDAAELNIACLQIKKACEKLI
>Mature_399_residues
SLITHRINRIKSSPTLAVAKKAAELQQQGKNIISLSVGELNFDTHDNIKAQAIEAINRGMTKYTNVDGMPELKQAVKNKF
KVENNLDYQLDELIVSSGAKQVIFNALLATLDIGDEVIIPTPYWVSYPDIVSLTGATSKFIYCHESSNFKITPAQLSNAI
TDKTKWLLLNSPNNPTGAIYTIEELKLLAEILSIHKNIHIMCDDIYEHIIFDNNKFYTLAAIAPSLKERIFIVNGVSKAY
AMTGWRIGYGAGNSEIIKAMIKIQSHSTSNPCSISQVAAIEALTGSQSHIQDNITILQRNRDLAFNILNNTIGLKCYKPT
GTFYLFVSCQELLHKATSTGQKINTSNDFACYLLEEAEVSVVPGEAFGINGYFRLSYAVDAAELNIACLQIKKACEKLI

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=427, Percent_Identity=24.5901639344262, Blast_Score=142, Evalue=6e-34,
Organism=Homo sapiens, GI169881279, Length=427, Percent_Identity=24.5901639344262, Blast_Score=142, Evalue=6e-34,
Organism=Homo sapiens, GI56713256, Length=377, Percent_Identity=25.9946949602122, Blast_Score=129, Evalue=4e-30,
Organism=Homo sapiens, GI56713254, Length=377, Percent_Identity=25.9946949602122, Blast_Score=129, Evalue=4e-30,
Organism=Homo sapiens, GI169881281, Length=303, Percent_Identity=24.0924092409241, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI4507369, Length=382, Percent_Identity=24.3455497382199, Blast_Score=113, Evalue=3e-25,
Organism=Escherichia coli, GI1788627, Length=363, Percent_Identity=27.5482093663912, Blast_Score=141, Evalue=6e-35,
Organism=Escherichia coli, GI1786816, Length=373, Percent_Identity=25.201072386059, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1788722, Length=391, Percent_Identity=28.6445012787724, Blast_Score=131, Evalue=8e-32,
Organism=Caenorhabditis elegans, GI17567663, Length=397, Percent_Identity=23.4256926952141, Blast_Score=127, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI71994476, Length=328, Percent_Identity=25, Blast_Score=108, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI71994472, Length=328, Percent_Identity=25, Blast_Score=108, Evalue=7e-24,
Organism=Caenorhabditis elegans, GI17567369, Length=297, Percent_Identity=23.2323232323232, Blast_Score=93, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI71981209, Length=308, Percent_Identity=22.7272727272727, Blast_Score=65, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6322401, Length=389, Percent_Identity=24.6786632390745, Blast_Score=117, Evalue=3e-27,
Organism=Saccharomyces cerevisiae, GI6320317, Length=369, Percent_Identity=24.6612466124661, Blast_Score=82, Evalue=1e-16,
Organism=Drosophila melanogaster, GI28573069, Length=294, Percent_Identity=23.1292517006803, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24646114, Length=294, Percent_Identity=23.1292517006803, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI28573067, Length=294, Percent_Identity=23.1292517006803, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI28573065, Length=294, Percent_Identity=23.1292517006803, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI18859735, Length=413, Percent_Identity=24.2130750605327, Blast_Score=113, Evalue=3e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 44235; Mature: 44104

Theoretical pI: Translated: 7.22; Mature: 7.22

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLITHRINRIKSSPTLAVAKKAAELQQQGKNIISLSVGELNFDTHDNIKAQAIEAINRG
CCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHCC
MTKYTNVDGMPELKQAVKNKFKVENNLDYQLDELIVSSGAKQVIFNALLATLDIGDEVII
CCEECCCCCCHHHHHHHHHHEECCCCCCHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEE
PTPYWVSYPDIVSLTGATSKFIYCHESSNFKITPAQLSNAITDKTKWLLLNSPNNPTGAI
CCCCEECCCCCEEECCCCEEEEEEEECCCEEEEHHHHHHHHCCCEEEEEEECCCCCCCEE
YTIEELKLLAEILSIHKNIHIMCDDIYEHIIFDNNKFYTLAAIAPSLKERIFIVNGVSKA
EEHHHHHHHHHHHHHCCCEEEEEHHHHHHHEECCCCEEEEEEECCCCCCEEEEEECCCHH
YAMTGWRIGYGAGNSEIIKAMIKIQSHSTSNPCSISQVAAIEALTGSQSHIQDNITILQR
HHCCCEEEEECCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCHHHHHCCEEEEEC
NRDLAFNILNNTIGLKCYKPTGTFYLFVSCQELLHKATSTGQKINTSNDFACYLLEEAEV
CCCEEEEEECCCCEEEEECCCCCEEEEEEHHHHHHHHHCCCCEECCCCCEEEEEEECCCE
SVVPGEAFGINGYFRLSYAVDAAELNIACLQIKKACEKLI
EEECCCEECCCCEEEEEEEEEHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SLITHRINRIKSSPTLAVAKKAAELQQQGKNIISLSVGELNFDTHDNIKAQAIEAINRG
CHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHCC
MTKYTNVDGMPELKQAVKNKFKVENNLDYQLDELIVSSGAKQVIFNALLATLDIGDEVII
CCEECCCCCCHHHHHHHHHHEECCCCCCHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEE
PTPYWVSYPDIVSLTGATSKFIYCHESSNFKITPAQLSNAITDKTKWLLLNSPNNPTGAI
CCCCEECCCCCEEECCCCEEEEEEEECCCEEEEHHHHHHHHCCCEEEEEEECCCCCCCEE
YTIEELKLLAEILSIHKNIHIMCDDIYEHIIFDNNKFYTLAAIAPSLKERIFIVNGVSKA
EEHHHHHHHHHHHHHCCCEEEEEHHHHHHHEECCCCEEEEEEECCCCCCEEEEEECCCHH
YAMTGWRIGYGAGNSEIIKAMIKIQSHSTSNPCSISQVAAIEALTGSQSHIQDNITILQR
HHCCCEEEEECCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCHHHHHCCEEEEEC
NRDLAFNILNNTIGLKCYKPTGTFYLFVSCQELLHKATSTGQKINTSNDFACYLLEEAEV
CCCEEEEEECCCCEEEEECCCCCEEEEEEHHHHHHHHHCCCCEECCCCCEEEEEEECCCE
SVVPGEAFGINGYFRLSYAVDAAELNIACLQIKKACEKLI
EEECCCEECCCCEEEEEEEEEHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA