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The map label for this gene is yleA [C]

Identifier: 189183909

GI number: 189183909

Start: 1049050

End: 1050321

Strand: Reverse

Name: yleA [C]

Synonym: OTT_1002

Alternate gene names: 189183909

Gene position: 1050321-1049050 (Counterclockwise)

Preceding gene: 189183917

Following gene: 189183908

Centisome position: 52.28

GC content: 31.6

Gene sequence:

>1272_bases
ATGAATGAAGATAAAATAAGTACTAGTACTTACACTAATAAGGTAATAACATTTGGTTGCCGCTTAAATGCATATGAAAG
TGAGATTATTAAACAGAATCTCAAAATTGCTAATCTTGATAATGTTGTAGTATTTAATACTTGTACTGTAACACAAGAAG
CTGAAAGGCAGGCTAAGCAAGCTATTAGAAAAGCAAAAAGAGAAAATCCTAACATTAAGATTATTGTTACTGGTTGCGCA
GCTCAGAACAACCCTGATCTCTTTAATCAAATGCCACAAGTGAATAAGATACTTGGCAATGAGGAAAAACTGTATCCTGA
ATTTTATCAATTTGATGAAAATAAAATTCAAGTAAATGATATTATGTCAATTCAAGAAACTGCTACTCATATGATTAGCA
ATTTTGATGGTAAAACGAGAGCGTTTATACAGGTCCAAAATGGCTGTAACCATCGCTGTACGTTTTGCATAATACCATAT
GCTCGAGGTAATAGTAGATCTGTACCAATTGGTGTAATAACTCAGCAGATTCAGCTTCTTATCAATCAAGGGTACAAGGA
AATAGTTTTTACAGGAGTAGATTTAACTTCTTATGGAGCTGACTTACCAGGATCTCCTACTTTAGCTCAAATGATTAAAC
GTGTTTTAATGCTAGTACCAGCTTTACCAAGATTGAGATTATCTTCAATAGATATAGCTGAAATAGATCAAGAATTATTT
AAATTGATGACTGATGAACCACGTTTAATGCCACACTTTCATATTAGTTTGCAAGCAGGTGATAATATGATATTAAAACG
TATGAAAAGACGTCACACTAGAGAACAAATAATAGAATTTTGCAACAAAATGCGCAAAATTCTTCCAGATGCATCATTTG
GAGCTGATATGATAGCTGGCTTTCCTACTGAAACTGAAATTATGTTTAACAATAGCTTAAACTTGATTTCAGAAACTGGA
ATTCAATATTTACATGTTTTCCCTTATTCAGAAAGAGAAAATACTCCAGCTAGTAAAATGCCACAAGTGCAAAAACACAT
CAGAAAAAAAAGAGCTCAATTATTGCGTAATGAAGGAAAAAAACAACTACAACTATTTTTTCAACAACAAATAGGCAAGA
TAGTTAAAGTGTTAGTAGAAAAAGAACAATTTGGACACAGTGAAAATTTTATTCCTACTTATATTGCTACTAGGCAAACA
ATAGGTGAGATAGTAAATGTAAAATTAACGAGTATTAATAATGATCATATGATTGGAACAGTGGTTAATTAA

Upstream 100 bases:

>100_bases
AAAAACTATCAACTATATTATATAGTAATATAGTTTGCTAATCTTAGTAAAGTAGTATTAAATAAAGCTACTTGATAATC
CTATAATTATAACAATTCAA

Downstream 100 bases:

>100_bases
ATCAACAATTTATACTTTTTAAAATCAAATAAACTATTTCAATAACTAAAATTATTTTAAATATGAAAATCGCAATAATA
GGAGCTGGAGCTTGGGGGAC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 423; Mature: 423

Protein sequence:

>423_residues
MNEDKISTSTYTNKVITFGCRLNAYESEIIKQNLKIANLDNVVVFNTCTVTQEAERQAKQAIRKAKRENPNIKIIVTGCA
AQNNPDLFNQMPQVNKILGNEEKLYPEFYQFDENKIQVNDIMSIQETATHMISNFDGKTRAFIQVQNGCNHRCTFCIIPY
ARGNSRSVPIGVITQQIQLLINQGYKEIVFTGVDLTSYGADLPGSPTLAQMIKRVLMLVPALPRLRLSSIDIAEIDQELF
KLMTDEPRLMPHFHISLQAGDNMILKRMKRRHTREQIIEFCNKMRKILPDASFGADMIAGFPTETEIMFNNSLNLISETG
IQYLHVFPYSERENTPASKMPQVQKHIRKKRAQLLRNEGKKQLQLFFQQQIGKIVKVLVEKEQFGHSENFIPTYIATRQT
IGEIVNVKLTSINNDHMIGTVVN

Sequences:

>Translated_423_residues
MNEDKISTSTYTNKVITFGCRLNAYESEIIKQNLKIANLDNVVVFNTCTVTQEAERQAKQAIRKAKRENPNIKIIVTGCA
AQNNPDLFNQMPQVNKILGNEEKLYPEFYQFDENKIQVNDIMSIQETATHMISNFDGKTRAFIQVQNGCNHRCTFCIIPY
ARGNSRSVPIGVITQQIQLLINQGYKEIVFTGVDLTSYGADLPGSPTLAQMIKRVLMLVPALPRLRLSSIDIAEIDQELF
KLMTDEPRLMPHFHISLQAGDNMILKRMKRRHTREQIIEFCNKMRKILPDASFGADMIAGFPTETEIMFNNSLNLISETG
IQYLHVFPYSERENTPASKMPQVQKHIRKKRAQLLRNEGKKQLQLFFQQQIGKIVKVLVEKEQFGHSENFIPTYIATRQT
IGEIVNVKLTSINNDHMIGTVVN
>Mature_423_residues
MNEDKISTSTYTNKVITFGCRLNAYESEIIKQNLKIANLDNVVVFNTCTVTQEAERQAKQAIRKAKRENPNIKIIVTGCA
AQNNPDLFNQMPQVNKILGNEEKLYPEFYQFDENKIQVNDIMSIQETATHMISNFDGKTRAFIQVQNGCNHRCTFCIIPY
ARGNSRSVPIGVITQQIQLLINQGYKEIVFTGVDLTSYGADLPGSPTLAQMIKRVLMLVPALPRLRLSSIDIAEIDQELF
KLMTDEPRLMPHFHISLQAGDNMILKRMKRRHTREQIIEFCNKMRKILPDASFGADMIAGFPTETEIMFNNSLNLISETG
IQYLHVFPYSERENTPASKMPQVQKHIRKKRAQLLRNEGKKQLQLFFQQQIGKIVKVLVEKEQFGHSENFIPTYIATRQT
IGEIVNVKLTSINNDHMIGTVVN

Specific function: Unknown

COG id: COG0621

COG function: function code J; 2-methylthioadenine synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MTTase N-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI28872784, Length=375, Percent_Identity=24.2666666666667, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI28872782, Length=375, Percent_Identity=24.2666666666667, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI93277076, Length=408, Percent_Identity=25.2450980392157, Blast_Score=127, Evalue=2e-29,
Organism=Escherichia coli, GI1786882, Length=438, Percent_Identity=26.2557077625571, Blast_Score=162, Evalue=4e-41,
Organism=Escherichia coli, GI1787057, Length=437, Percent_Identity=27.2311212814645, Blast_Score=144, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI17553146, Length=429, Percent_Identity=26.5734265734266, Blast_Score=151, Evalue=7e-37,
Organism=Caenorhabditis elegans, GI71996771, Length=287, Percent_Identity=24.0418118466899, Blast_Score=105, Evalue=3e-23,
Organism=Drosophila melanogaster, GI21356207, Length=398, Percent_Identity=26.1306532663317, Blast_Score=148, Evalue=5e-36,
Organism=Drosophila melanogaster, GI19922432, Length=441, Percent_Identity=24.7165532879819, Blast_Score=135, Evalue=7e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR005839
- InterPro:   IPR020612
- InterPro:   IPR013848
- InterPro:   IPR006467
- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM; PF00919 UPF0004 [H]

EC number: NA

Molecular weight: Translated: 48325; Mature: 48325

Theoretical pI: Translated: 9.28; Mature: 9.28

Prosite motif: PS50926 TRAM ; PS01278 UPF0004

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEDKISTSTYTNKVITFGCRLNAYESEIIKQNLKIANLDNVVVFNTCTVTQEAERQAKQ
CCCCCCCCCHHCCEEEEEEEECCHHHHHHHHCCCCEECCCCEEEEEEECCCHHHHHHHHH
AIRKAKRENPNIKIIVTGCAAQNNPDLFNQMPQVNKILGNEEKLYPEFYQFDENKIQVND
HHHHHHHCCCCEEEEEEECCCCCCCHHHHHCCHHHHHHCCCHHCCCHHHHCCCCEEEHHH
IMSIQETATHMISNFDGKTRAFIQVQNGCNHRCTFCIIPYARGNSRSVPIGVITQQIQLL
HHHHHHHHHHHHHCCCCCEEEEEEECCCCCCEEEEEEEEECCCCCCCCCHHHHHHHHHHH
INQGYKEIVFTGVDLTSYGADLPGSPTLAQMIKRVLMLVPALPRLRLSSIDIAEIDQELF
HHCCCCEEEEECCCHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCEECCCCHHHHHHHHH
KLMTDEPRLMPHFHISLQAGDNMILKRMKRRHTREQIIEFCNKMRKILPDASFGADMIAG
HHHCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCC
FPTETEIMFNNSLNLISETGIQYLHVFPYSERENTPASKMPQVQKHIRKKRAQLLRNEGK
CCCCEEEEECCCCHHHHHCCCEEEEEECCCCCCCCCHHCCHHHHHHHHHHHHHHHHHCCH
KQLQLFFQQQIGKIVKVLVEKEQFGHSENFIPTYIATRQTIGEIVNVKLTSINNDHMIGT
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHEEEEEEECCCEEEEE
VVN
ECC
>Mature Secondary Structure
MNEDKISTSTYTNKVITFGCRLNAYESEIIKQNLKIANLDNVVVFNTCTVTQEAERQAKQ
CCCCCCCCCHHCCEEEEEEEECCHHHHHHHHCCCCEECCCCEEEEEEECCCHHHHHHHHH
AIRKAKRENPNIKIIVTGCAAQNNPDLFNQMPQVNKILGNEEKLYPEFYQFDENKIQVND
HHHHHHHCCCCEEEEEEECCCCCCCHHHHHCCHHHHHHCCCHHCCCHHHHCCCCEEEHHH
IMSIQETATHMISNFDGKTRAFIQVQNGCNHRCTFCIIPYARGNSRSVPIGVITQQIQLL
HHHHHHHHHHHHHCCCCCEEEEEEECCCCCCEEEEEEEEECCCCCCCCCHHHHHHHHHHH
INQGYKEIVFTGVDLTSYGADLPGSPTLAQMIKRVLMLVPALPRLRLSSIDIAEIDQELF
HHCCCCEEEEECCCHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCEECCCCHHHHHHHHH
KLMTDEPRLMPHFHISLQAGDNMILKRMKRRHTREQIIEFCNKMRKILPDASFGADMIAG
HHHCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCC
FPTETEIMFNNSLNLISETGIQYLHVFPYSERENTPASKMPQVQKHIRKKRAQLLRNEGK
CCCCEEEEECCCCHHHHHCCCEEEEEECCCCCCCCCHHCCHHHHHHHHHHHHHHHHHCCH
KQLQLFFQQQIGKIVKVLVEKEQFGHSENFIPTYIATRQTIGEIVNVKLTSINNDHMIGT
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHEEEEEEECCCEEEEE
VVN
ECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9823893 [H]