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The map label for this gene is gpsA [H]

Identifier: 189183908

GI number: 189183908

Start: 1047995

End: 1048987

Strand: Reverse

Name: gpsA [H]

Synonym: OTT_1001

Alternate gene names: 189183908

Gene position: 1048987-1047995 (Counterclockwise)

Preceding gene: 189183909

Following gene: 189183906

Centisome position: 52.21

GC content: 31.42

Gene sequence:

>993_bases
ATGAAAATCGCAATAATAGGAGCTGGAGCTTGGGGGACAGCGATAGCTATGCTTCTAGCTCGTAATAATTACAGAGTAAC
ATTATATACTAGACACTCAGCCCATACTCAAGAAATCAATCAGCTGCATACTAATAAAAAATACCTACCTAATATCATAT
TACCAAATATCATTAAGGCTACTAGCAGCTTTTCTGATATTGTTGATCATGAAATAATCATTATTGTTACACCATCAGAT
CAAGTAAGAGCTACTATTAAAAATTTAAAGCAACATGGCATATCTAATAATGCCATTATTGGAATTGCATCAAAAGGATT
AGATCATAATCAATCTAAACTATTAAGTGACGTAGTAAAAGATTATTTAGCAAATAATCCTTTATTCATCATAGCTGGAC
CAAATTTAGCAAATGAGGTAGCCCAAGGTTTGCCATGCGCTCTGACAATTGCTGCTATACAAAAAGAAGTGCGATTCAAC
ATTTCTACATTATTTCATAGCCCTAATGTTATAACTAGTACTACTGAAGATATTATTACTATTCAAGTTGCAAGCGCATT
TAAAAATATCATTGCTATCATTGCTGGTATTATTATTGCTAAACAATATGGTCAAAACTGTAAAGCATCTATTATAACTC
AAGGAATAAAGGAAATTGTGGCATTTGCTAGAGCAGCTGGCAGTACAAACCCAGATATTAGTGAATTTGCAGTAATAGGA
GACCTAATATTAACTAGTTATGCCATTACTTCTCGTAATACAAAATTTGGTTATGATTTAGGGCAATATGAATACTATAC
TGATCTAAGCAATAATACTAATCCAAATTTAATAGAAGGAATTAAAGCAGCTAAAATCTTATATCCTCTAACAGTTAAAC
TAAACCTTAATTGTCATATTATTTACTGCGCTTATTCGATATTACATAATGGAGGCAAAATAAGCTCTGCTATAGAATGC
ATGTTAAAGAAAATTAATCATGAAACAAAGTAG

Upstream 100 bases:

>100_bases
TTAATAATGATCATATGATTGGAACAGTGGTTAATTAAATCAACAATTTATACTTTTTAAAATCAAATAAACTATTTCAA
TAACTAAAATTATTTTAAAT

Downstream 100 bases:

>100_bases
TAACTGTGTAAATTATTAGTCATTTAAGTAGGAAATTAATATTACAGAAATCTGATTACAAACAGAAAGATATTGCGGTG
CCGATAAAGGGAGTTGAACC

Product: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase [H]

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MKIAIIGAGAWGTAIAMLLARNNYRVTLYTRHSAHTQEINQLHTNKKYLPNIILPNIIKATSSFSDIVDHEIIIIVTPSD
QVRATIKNLKQHGISNNAIIGIASKGLDHNQSKLLSDVVKDYLANNPLFIIAGPNLANEVAQGLPCALTIAAIQKEVRFN
ISTLFHSPNVITSTTEDIITIQVASAFKNIIAIIAGIIIAKQYGQNCKASIITQGIKEIVAFARAAGSTNPDISEFAVIG
DLILTSYAITSRNTKFGYDLGQYEYYTDLSNNTNPNLIEGIKAAKILYPLTVKLNLNCHIIYCAYSILHNGGKISSAIEC
MLKKINHETK

Sequences:

>Translated_330_residues
MKIAIIGAGAWGTAIAMLLARNNYRVTLYTRHSAHTQEINQLHTNKKYLPNIILPNIIKATSSFSDIVDHEIIIIVTPSD
QVRATIKNLKQHGISNNAIIGIASKGLDHNQSKLLSDVVKDYLANNPLFIIAGPNLANEVAQGLPCALTIAAIQKEVRFN
ISTLFHSPNVITSTTEDIITIQVASAFKNIIAIIAGIIIAKQYGQNCKASIITQGIKEIVAFARAAGSTNPDISEFAVIG
DLILTSYAITSRNTKFGYDLGQYEYYTDLSNNTNPNLIEGIKAAKILYPLTVKLNLNCHIIYCAYSILHNGGKISSAIEC
MLKKINHETK
>Mature_330_residues
MKIAIIGAGAWGTAIAMLLARNNYRVTLYTRHSAHTQEINQLHTNKKYLPNIILPNIIKATSSFSDIVDHEIIIIVTPSD
QVRATIKNLKQHGISNNAIIGIASKGLDHNQSKLLSDVVKDYLANNPLFIIAGPNLANEVAQGLPCALTIAAIQKEVRFN
ISTLFHSPNVITSTTEDIITIQVASAFKNIIAIIAGIIIAKQYGQNCKASIITQGIKEIVAFARAAGSTNPDISEFAVIG
DLILTSYAITSRNTKFGYDLGQYEYYTDLSNNTNPNLIEGIKAAKILYPLTVKLNLNCHIIYCAYSILHNGGKISSAIEC
MLKKINHETK

Specific function: De novo phospholipid biosynthesis; glycerol-3 phosphate formation. [C]

COG id: COG0240

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI33695088, Length=351, Percent_Identity=27.9202279202279, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI24307999, Length=272, Percent_Identity=28.6764705882353, Blast_Score=105, Evalue=5e-23,
Organism=Escherichia coli, GI1790037, Length=331, Percent_Identity=28.0966767371601, Blast_Score=150, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI32564399, Length=274, Percent_Identity=29.5620437956204, Blast_Score=95, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI193210136, Length=283, Percent_Identity=28.6219081272085, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI32564403, Length=283, Percent_Identity=28.6219081272085, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17507425, Length=281, Percent_Identity=29.1814946619217, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI193210134, Length=270, Percent_Identity=28.1481481481481, Blast_Score=80, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6324513, Length=287, Percent_Identity=29.616724738676, Blast_Score=89, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6320181, Length=287, Percent_Identity=29.2682926829268, Blast_Score=87, Evalue=5e-18,
Organism=Drosophila melanogaster, GI17136204, Length=274, Percent_Identity=29.9270072992701, Blast_Score=93, Evalue=3e-19,
Organism=Drosophila melanogaster, GI17136202, Length=274, Percent_Identity=29.9270072992701, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI17136200, Length=274, Percent_Identity=29.9270072992701, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI22026922, Length=275, Percent_Identity=29.4545454545455, Blast_Score=91, Evalue=8e-19,
Organism=Drosophila melanogaster, GI281362270, Length=239, Percent_Identity=27.6150627615063, Blast_Score=85, Evalue=5e-17,
Organism=Drosophila melanogaster, GI45551945, Length=239, Percent_Identity=27.6150627615063, Blast_Score=85, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24648969, Length=228, Percent_Identity=25.8771929824561, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR006168
- InterPro:   IPR006109
- InterPro:   IPR011128
- InterPro:   IPR016040 [H]

Pfam domain/function: PF07479 NAD_Gly3P_dh_C; PF01210 NAD_Gly3P_dh_N [H]

EC number: =1.1.1.94 [H]

Molecular weight: Translated: 36000; Mature: 36000

Theoretical pI: Translated: 9.21; Mature: 9.21

Prosite motif: PS00957 NAD_G3PDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIAIIGAGAWGTAIAMLLARNNYRVTLYTRHSAHTQEINQLHTNKKYLPNIILPNIIKA
CEEEEEECCHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHCCCHHCCCHHHHHHHHH
TSSFSDIVDHEIIIIVTPSDQVRATIKNLKQHGISNNAIIGIASKGLDHNQSKLLSDVVK
HHHHHHHCCCCEEEEECCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHH
DYLANNPLFIIAGPNLANEVAQGLPCALTIAAIQKEVRFNISTLFHSPNVITSTTEDIIT
HHHCCCCEEEEECCCHHHHHHCCCCCEEEHHHHHHHHHHHHHHEEECCCEEECCCCCEEE
IQVASAFKNIIAIIAGIIIAKQYGQNCKASIITQGIKEIVAFARAAGSTNPDISEFAVIG
EEHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
DLILTSYAITSRNTKFGYDLGQYEYYTDLSNNTNPNLIEGIKAAKILYPLTVKLNLNCHI
HHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHEEEEEEEEEEECCEEE
IYCAYSILHNGGKISSAIECMLKKINHETK
EEEEHHHHHCCCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKIAIIGAGAWGTAIAMLLARNNYRVTLYTRHSAHTQEINQLHTNKKYLPNIILPNIIKA
CEEEEEECCHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHCCCHHCCCHHHHHHHHH
TSSFSDIVDHEIIIIVTPSDQVRATIKNLKQHGISNNAIIGIASKGLDHNQSKLLSDVVK
HHHHHHHCCCCEEEEECCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHH
DYLANNPLFIIAGPNLANEVAQGLPCALTIAAIQKEVRFNISTLFHSPNVITSTTEDIIT
HHHCCCCEEEEECCCHHHHHHCCCCCEEEHHHHHHHHHHHHHHEEECCCEEECCCCCEEE
IQVASAFKNIIAIIAGIIIAKQYGQNCKASIITQGIKEIVAFARAAGSTNPDISEFAVIG
EEHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
DLILTSYAITSRNTKFGYDLGQYEYYTDLSNNTNPNLIEGIKAAKILYPLTVKLNLNCHI
HHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHEEEEEEEEEEECCEEE
IYCAYSILHNGGKISSAIECMLKKINHETK
EEEEHHHHHCCCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA