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The map label for this gene is tppB [H]

Identifier: 189183758

GI number: 189183758

Start: 895036

End: 896514

Strand: Reverse

Name: tppB [H]

Synonym: OTT_0851

Alternate gene names: 189183758

Gene position: 896514-895036 (Counterclockwise)

Preceding gene: 189183759

Following gene: 189183755

Centisome position: 44.63

GC content: 31.1

Gene sequence:

>1479_bases
ATGAATAAATCAATCAGTGTATTAAATACAACAACCACAGTTAGAAAATTTCCACAATTTTTGTTGTTATTATTCTTTGT
TGAGATGTGGGAACGCTTTAGTTATTATGGAATGAGGGCGCTTTTAGTGCTTTTTTTAACTTCTCAGTTAGGCTTTACTG
ATATAAAAGCTTATACTACATACTCTTTATTCGCTGTAATAGGTTATGCTGGACCAGTGATTGGAGGGCTTTTAGCTGAT
AAATTAATGGGGTTCCGCAACATGGTACTAATAGGAGGAATTGTTATAGTAGCTGGACATATGAGCATACTCCTAGTAGG
ATTTAATTCAGACATAATATATTTTAGCCTATCTTTAATAGCTGTAGGTACTGGAATGTTTAAAGGTAATATCGTAAACT
TGCTTGGAGCTTGTTATAGAAAGGATGATTCTGAACGTAGTAGAGGATTTACTTTATTTTATGTAGGTGTTAATTTAGGC
GGGGCATTAGCAGCTATTTCTTGTGGATATATTGCTCATTTATATGGCTGGCATTATGGATTTGGCTTAGCAGGAATTGG
AATGATTATTGGCCTTATTACTTTTATAAAATTTCAACACATTTTAGGAGATAAAGGCCTGTCTGCATACCCTATGCTTA
TGAACAAAAGAATACTAGGAATAAATGTTTTTGGAATAGTATTCGCTAGTTGCTTCTTGTTAGCATTAATGGTATCTACA
ATGCTTATATTTAGCGAGTTTTTTACTTCTGCACTTACATTTAGTGGAATAATAGTTCTAGGGGTATTTGTTAGTATAAT
ATTTAAAACATCACTTGAGCAAAGGCCAAAGTTGATAGTATTAGCAATTCTTATAATATTCCAGATGTTATTTTTTGCAC
TAGAAATGCAACTTGGCTCTTTAATTAACTTGTTTACTGAAAGAAATGTTGCCAACAATATCTTAGGTATAACAATTCCA
GCTTCAGTATCTCAAGCAATCAATCCTGTATCAATTATAATACTTGGATCTCTTTTTGGAATGTTTTCGAAGTTCAGAAA
AAAAGATGCCACTGCTATCTTTGCTTTTGGTCTTTTTACAATTTCTATATGTTTTTTTATTTTATATACAGGATGTTTAA
ATGCTAATGATGGAAAAGTAAACTATTTATATCTAATAGCTGCTATTTCTATTATGGGATTAGGAGAGCTTTGCGTTGCG
CCATTAGTACAAGAACAAGCAATTTTATTATCTCCTAAAAATGCAAAAGGAGCATTAATGGGTATGATGATATTATCATT
AGCATTTTCTAACCTAATTGGTATGGCAGTATCAAACTCTATGTTAGTACCTTCGGTAAATGGCGAAGTAAATCGTTTTG
AATCTTTAGCAATATATCAAGAGGGATTTTTAAATGTAACAATATCTGCTGCAATATTAAGTATTATATTTTTACTTTTT
TTTAAAATAATACATAAAGTTATTGCTATGCAAGAATAA

Upstream 100 bases:

>100_bases
ATTTTGATTGTTAATCTTTTTTTAATGAAGCTATAAGTATAGAGTCATAATTTACTTAAAATTACTTTAAAATTAACTAA
TTAGTGTAATGGAATAGTTT

Downstream 100 bases:

>100_bases
TTACAATTTTAAATAGGATTTTAACTATTTATAAAACACAAAAGTTTGATATAATTGAGAACAACAGAAAGCAGGAAAAA
TATGCTGTAATCTTTATATC

Product: tripeptide permease TppB, putative POT family peptide transport protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 492; Mature: 492

Protein sequence:

>492_residues
MNKSISVLNTTTTVRKFPQFLLLLFFVEMWERFSYYGMRALLVLFLTSQLGFTDIKAYTTYSLFAVIGYAGPVIGGLLAD
KLMGFRNMVLIGGIVIVAGHMSILLVGFNSDIIYFSLSLIAVGTGMFKGNIVNLLGACYRKDDSERSRGFTLFYVGVNLG
GALAAISCGYIAHLYGWHYGFGLAGIGMIIGLITFIKFQHILGDKGLSAYPMLMNKRILGINVFGIVFASCFLLALMVST
MLIFSEFFTSALTFSGIIVLGVFVSIIFKTSLEQRPKLIVLAILIIFQMLFFALEMQLGSLINLFTERNVANNILGITIP
ASVSQAINPVSIIILGSLFGMFSKFRKKDATAIFAFGLFTISICFFILYTGCLNANDGKVNYLYLIAAISIMGLGELCVA
PLVQEQAILLSPKNAKGALMGMMILSLAFSNLIGMAVSNSMLVPSVNGEVNRFESLAIYQEGFLNVTISAAILSIIFLLF
FKIIHKVIAMQE

Sequences:

>Translated_492_residues
MNKSISVLNTTTTVRKFPQFLLLLFFVEMWERFSYYGMRALLVLFLTSQLGFTDIKAYTTYSLFAVIGYAGPVIGGLLAD
KLMGFRNMVLIGGIVIVAGHMSILLVGFNSDIIYFSLSLIAVGTGMFKGNIVNLLGACYRKDDSERSRGFTLFYVGVNLG
GALAAISCGYIAHLYGWHYGFGLAGIGMIIGLITFIKFQHILGDKGLSAYPMLMNKRILGINVFGIVFASCFLLALMVST
MLIFSEFFTSALTFSGIIVLGVFVSIIFKTSLEQRPKLIVLAILIIFQMLFFALEMQLGSLINLFTERNVANNILGITIP
ASVSQAINPVSIIILGSLFGMFSKFRKKDATAIFAFGLFTISICFFILYTGCLNANDGKVNYLYLIAAISIMGLGELCVA
PLVQEQAILLSPKNAKGALMGMMILSLAFSNLIGMAVSNSMLVPSVNGEVNRFESLAIYQEGFLNVTISAAILSIIFLLF
FKIIHKVIAMQE
>Mature_492_residues
MNKSISVLNTTTTVRKFPQFLLLLFFVEMWERFSYYGMRALLVLFLTSQLGFTDIKAYTTYSLFAVIGYAGPVIGGLLAD
KLMGFRNMVLIGGIVIVAGHMSILLVGFNSDIIYFSLSLIAVGTGMFKGNIVNLLGACYRKDDSERSRGFTLFYVGVNLG
GALAAISCGYIAHLYGWHYGFGLAGIGMIIGLITFIKFQHILGDKGLSAYPMLMNKRILGINVFGIVFASCFLLALMVST
MLIFSEFFTSALTFSGIIVLGVFVSIIFKTSLEQRPKLIVLAILIIFQMLFFALEMQLGSLINLFTERNVANNILGITIP
ASVSQAINPVSIIILGSLFGMFSKFRKKDATAIFAFGLFTISICFFILYTGCLNANDGKVNYLYLIAAISIMGLGELCVA
PLVQEQAILLSPKNAKGALMGMMILSLAFSNLIGMAVSNSMLVPSVNGEVNRFESLAIYQEGFLNVTISAAILSIIFLLF
FKIIHKVIAMQE

Specific function: Proton-dependent permease that transports di- and tripeptides [H]

COG id: COG3104

COG function: function code E; Dipeptide/tripeptide permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTR2/POT transporter (TC 2.A.17) family. DtpA subfamily [H]

Homologues:

Organism=Homo sapiens, GI4827008, Length=206, Percent_Identity=28.6407766990291, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI226371746, Length=186, Percent_Identity=29.0322580645161, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI226371748, Length=179, Percent_Identity=29.608938547486, Blast_Score=70, Evalue=4e-12,
Organism=Escherichia coli, GI1786927, Length=497, Percent_Identity=31.3883299798793, Blast_Score=223, Evalue=3e-59,
Organism=Escherichia coli, GI1787922, Length=479, Percent_Identity=31.5240083507307, Blast_Score=221, Evalue=6e-59,
Organism=Escherichia coli, GI1790572, Length=478, Percent_Identity=30.7531380753138, Blast_Score=209, Evalue=2e-55,
Organism=Escherichia coli, GI1789911, Length=504, Percent_Identity=28.7698412698413, Blast_Score=184, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI71987453, Length=161, Percent_Identity=34.1614906832298, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24639583, Length=347, Percent_Identity=26.8011527377522, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24639581, Length=340, Percent_Identity=27.0588235294118, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24639585, Length=340, Percent_Identity=27.0588235294118, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR000109
- InterPro:   IPR005279
- InterPro:   IPR018456 [H]

Pfam domain/function: PF00854 PTR2 [H]

EC number: NA

Molecular weight: Translated: 53799; Mature: 53799

Theoretical pI: Translated: 9.45; Mature: 9.45

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKSISVLNTTTTVRKFPQFLLLLFFVEMWERFSYYGMRALLVLFLTSQLGFTDIKAYTT
CCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
YSLFAVIGYAGPVIGGLLADKLMGFRNMVLIGGIVIVAGHMSILLVGFNSDIIYFSLSLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHH
AVGTGMFKGNIVNLLGACYRKDDSERSRGFTLFYVGVNLGGALAAISCGYIAHLYGWHYG
HHHCCHHCCHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHH
FGLAGIGMIIGLITFIKFQHILGDKGLSAYPMLMNKRILGINVFGIVFASCFLLALMVST
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCEEEEEHHHHHHHHHHHHHHHHHHH
MLIFSEFFTSALTFSGIIVLGVFVSIIFKTSLEQRPKLIVLAILIIFQMLFFALEMQLGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
LINLFTERNVANNILGITIPASVSQAINPVSIIILGSLFGMFSKFRKKDATAIFAFGLFT
HHHHHHHCCHHCCEEEEEECHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
ISICFFILYTGCLNANDGKVNYLYLIAAISIMGLGELCVAPLVQEQAILLSPKNAKGALM
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHCCEEEECCCCCCHHHH
GMMILSLAFSNLIGMAVSNSMLVPSVNGEVNRFESLAIYQEGFLNVTISAAILSIIFLLF
HHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHH
FKIIHKVIAMQE
HHHHHHHHHCCC
>Mature Secondary Structure
MNKSISVLNTTTTVRKFPQFLLLLFFVEMWERFSYYGMRALLVLFLTSQLGFTDIKAYTT
CCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
YSLFAVIGYAGPVIGGLLADKLMGFRNMVLIGGIVIVAGHMSILLVGFNSDIIYFSLSLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHH
AVGTGMFKGNIVNLLGACYRKDDSERSRGFTLFYVGVNLGGALAAISCGYIAHLYGWHYG
HHHCCHHCCHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHH
FGLAGIGMIIGLITFIKFQHILGDKGLSAYPMLMNKRILGINVFGIVFASCFLLALMVST
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCEEEEEHHHHHHHHHHHHHHHHHHH
MLIFSEFFTSALTFSGIIVLGVFVSIIFKTSLEQRPKLIVLAILIIFQMLFFALEMQLGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
LINLFTERNVANNILGITIPASVSQAINPVSIIILGSLFGMFSKFRKKDATAIFAFGLFT
HHHHHHHCCHHCCEEEEEECHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
ISICFFILYTGCLNANDGKVNYLYLIAAISIMGLGELCVAPLVQEQAILLSPKNAKGALM
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHCCEEEECCCCCCHHHH
GMMILSLAFSNLIGMAVSNSMLVPSVNGEVNRFESLAIYQEGFLNVTISAAILSIIFLLF
HHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHH
FKIIHKVIAMQE
HHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]