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The map label for this gene is dapE [H]

Identifier: 189183699

GI number: 189183699

Start: 834545

End: 835711

Strand: Direct

Name: dapE [H]

Synonym: OTT_0792

Alternate gene names: 189183699

Gene position: 834545-835711 (Clockwise)

Preceding gene: 189183698

Following gene: 189183700

Centisome position: 41.54

GC content: 28.53

Gene sequence:

>1167_bases
GTGATAAGTAAAAAATTAATTATTGAGCTATTAAAACAGTTAATAAGCTTTAAGTCTGTTACACCAAATGATAATGGTGC
AATAGACTTTATTACTAATTTACTTGTAAAACAAGGGTTTAAGGTTTATGTCAAGGAATTTGGTCAAGAATATAAAGTTA
AAAATCTTTATGGATATTTTGGTAACGGGCAGCCAAATATATGTTTTGCTGGTCACATTGATGTAGTACCTGCTGGATTT
ATTGAACAATGGAAATATCCTCCTTTTTGCGCTACTCAGTATAAAGATAAAATTTATGGTAGAGGTGTTGTAGATATGAA
AGGGGCAATATCTGCAATGCTATCTGCAGTATTCTGTTTTATTGATAATAATAATGATTTTAATGGAACAATTAGTTTTT
TAATTACAGCTGATGAGGAAGGTGAAGCATTATTTGGTACCAAGAAAATGTTGGAGTGGATTAACAAGCAAGGGCATAAA
ATAGATTTTACTATTTTAGGCGAACCGACATGTACAGATAAAATTGGTGATACTATAAAAATTGGCAGACGTGGCAGTAT
AAATTTCGATTTAAAAGTCTTTGGCAAGCAAGGTCATGTAGCCTATCCACATTTGGCTATTAATCCAAATCATTTAATTG
TGAAGATTTTGAATAGTTTTATTGGTTCTAAGATAGATGAAGGCAATGAATTTTTCGCACCATCTAATTTAGAAGTTGTT
TCAATAGATACAAACAATAATATTACAAATATTATACCTGAAATAGCTCAATCAAAGTTTAATATCAGGTTTAATGATAT
TCATACTAATGAACAGTTGTTAGAGATTGTTAAAAAAAATATTGAACAATTTACTACAAACTATGACTTACAATCAAGTT
GCAGGTCAAGACCATTTTTAGCAAAAATGTCTCCTTATATTTTCAGTTTTAAAGAATTAGTACATAAAGTAACAAAAATA
AAGCCAGAATTTTCAACTTCAGGAGGTACATCTGATGCTTATTTTTTTAAAGATTATTCTCCTATTGTAGAATTTGGATT
ATTAAATACTATGGCTCACAAAATTAATGAGTATTGTTTAATTAATGATTTACAAACTTTATGTAGAGTGTATTATAATG
CTTTATGCTTGTTTCTAATGAGCAATAGCAAATTTAGAACAAATTAA

Upstream 100 bases:

>100_bases
GCGCTTATACTAACATAATGTTGCTGAAAAACAACTGCGACCTAAGTTTCTAAAAGCTTTTTAGCTATAGCTATAAAATT
GAATATTAAAAATTAACTGA

Downstream 100 bases:

>100_bases
AGTATAATTAATTTAAAGCGGGTGTGGCGAAATTGGTAGACGTACCAGATTTAGGTTCTGGCGCCGAAAGGCATGGGGGT
TCAATTCCCTCCACCCGTAC

Product: succinyl-diaminopimelate desuccinylase

Products: NA

Alternate protein names: SDAP desuccinylase; N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase [H]

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MISKKLIIELLKQLISFKSVTPNDNGAIDFITNLLVKQGFKVYVKEFGQEYKVKNLYGYFGNGQPNICFAGHIDVVPAGF
IEQWKYPPFCATQYKDKIYGRGVVDMKGAISAMLSAVFCFIDNNNDFNGTISFLITADEEGEALFGTKKMLEWINKQGHK
IDFTILGEPTCTDKIGDTIKIGRRGSINFDLKVFGKQGHVAYPHLAINPNHLIVKILNSFIGSKIDEGNEFFAPSNLEVV
SIDTNNNITNIIPEIAQSKFNIRFNDIHTNEQLLEIVKKNIEQFTTNYDLQSSCRSRPFLAKMSPYIFSFKELVHKVTKI
KPEFSTSGGTSDAYFFKDYSPIVEFGLLNTMAHKINEYCLINDLQTLCRVYYNALCLFLMSNSKFRTN

Sequences:

>Translated_388_residues
MISKKLIIELLKQLISFKSVTPNDNGAIDFITNLLVKQGFKVYVKEFGQEYKVKNLYGYFGNGQPNICFAGHIDVVPAGF
IEQWKYPPFCATQYKDKIYGRGVVDMKGAISAMLSAVFCFIDNNNDFNGTISFLITADEEGEALFGTKKMLEWINKQGHK
IDFTILGEPTCTDKIGDTIKIGRRGSINFDLKVFGKQGHVAYPHLAINPNHLIVKILNSFIGSKIDEGNEFFAPSNLEVV
SIDTNNNITNIIPEIAQSKFNIRFNDIHTNEQLLEIVKKNIEQFTTNYDLQSSCRSRPFLAKMSPYIFSFKELVHKVTKI
KPEFSTSGGTSDAYFFKDYSPIVEFGLLNTMAHKINEYCLINDLQTLCRVYYNALCLFLMSNSKFRTN
>Mature_388_residues
MISKKLIIELLKQLISFKSVTPNDNGAIDFITNLLVKQGFKVYVKEFGQEYKVKNLYGYFGNGQPNICFAGHIDVVPAGF
IEQWKYPPFCATQYKDKIYGRGVVDMKGAISAMLSAVFCFIDNNNDFNGTISFLITADEEGEALFGTKKMLEWINKQGHK
IDFTILGEPTCTDKIGDTIKIGRRGSINFDLKVFGKQGHVAYPHLAINPNHLIVKILNSFIGSKIDEGNEFFAPSNLEVV
SIDTNNNITNIIPEIAQSKFNIRFNDIHTNEQLLEIVKKNIEQFTTNYDLQSSCRSRPFLAKMSPYIFSFKELVHKVTKI
KPEFSTSGGTSDAYFFKDYSPIVEFGLLNTMAHKINEYCLINDLQTLCRVYYNALCLFLMSNSKFRTN

Specific function: Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bact

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family. DapE subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788816, Length=370, Percent_Identity=36.4864864864865, Blast_Score=253, Evalue=1e-68,
Organism=Escherichia coli, GI1790395, Length=223, Percent_Identity=27.3542600896861, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17551016, Length=222, Percent_Identity=27.4774774774775, Blast_Score=73, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005941
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.18 [H]

Molecular weight: Translated: 44016; Mature: 44016

Theoretical pI: Translated: 8.19; Mature: 8.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISKKLIIELLKQLISFKSVTPNDNGAIDFITNLLVKQGFKVYVKEFGQEYKVKNLYGYF
CCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHCCCCEECCEEEEE
GNGQPNICFAGHIDVVPAGFIEQWKYPPFCATQYKDKIYGRGVVDMKGAISAMLSAVFCF
CCCCCCEEEECCCCCCCCHHHHHCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHEEE
IDNNNDFNGTISFLITADEEGEALFGTKKMLEWINKQGHKIDFTILGEPTCTDKIGDTIK
EECCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHCCCEEE
IGRRGSINFDLKVFGKQGHVAYPHLAINPNHLIVKILNSFIGSKIDEGNEFFAPSNLEVV
ECCCCCCEEEEEEECCCCCEECCEEEECCCHHHHHHHHHHHCCCCCCCCCEECCCCCEEE
SIDTNNNITNIIPEIAQSKFNIRFNDIHTNEQLLEIVKKNIEQFTTNYDLQSSCRSRPFL
EEECCCCHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHCCCCHHHHHCCCCCH
AKMSPYIFSFKELVHKVTKIKPEFSTSGGTSDAYFFKDYSPIVEFGLLNTMAHKINEYCL
HHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHCCHH
INDLQTLCRVYYNALCLFLMSNSKFRTN
HHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MISKKLIIELLKQLISFKSVTPNDNGAIDFITNLLVKQGFKVYVKEFGQEYKVKNLYGYF
CCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHCCCCEECCEEEEE
GNGQPNICFAGHIDVVPAGFIEQWKYPPFCATQYKDKIYGRGVVDMKGAISAMLSAVFCF
CCCCCCEEEECCCCCCCCHHHHHCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHEEE
IDNNNDFNGTISFLITADEEGEALFGTKKMLEWINKQGHKIDFTILGEPTCTDKIGDTIK
EECCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHCCCEEE
IGRRGSINFDLKVFGKQGHVAYPHLAINPNHLIVKILNSFIGSKIDEGNEFFAPSNLEVV
ECCCCCCEEEEEEECCCCCEECCEEEECCCHHHHHHHHHHHCCCCCCCCCEECCCCCEEE
SIDTNNNITNIIPEIAQSKFNIRFNDIHTNEQLLEIVKKNIEQFTTNYDLQSSCRSRPFL
EEECCCCHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHCCCCHHHHHCCCCCH
AKMSPYIFSFKELVHKVTKIKPEFSTSGGTSDAYFFKDYSPIVEFGLLNTMAHKINEYCL
HHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHCCHH
INDLQTLCRVYYNALCLFLMSNSKFRTN
HHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA