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The map label for this gene is tig [H]

Identifier: 189183700

GI number: 189183700

Start: 835863

End: 837332

Strand: Direct

Name: tig [H]

Synonym: OTT_0793

Alternate gene names: 189183700

Gene position: 835863-837332 (Clockwise)

Preceding gene: 189183699

Following gene: 189183703

Centisome position: 41.61

GC content: 31.02

Gene sequence:

>1470_bases
ATGTCTCAAATCATCGAGTTGCAGAGTGAAGGCCTTGAAAAGCATTTTCAAATTTCTATTCCTGCAAGTGTAATAAAAGA
TAAGACTGATCAAAAGGTTATCTCTTTAACTGCAAGGGCAAATATGCCTGGATTTAGAAAGTTTAAGTCAGGATCTCACA
TTACTTCAAAAGCAATGCAAGTAAAGCAAATGCAAGTTCGAAGACAGTATGAAGCATCAATAAGAAATGATGTTCAAAAT
GATGTTATTGTTGCTGCGGTAGAAAGTTTAATCAAGTCTAATAATTTTTCACTAATTGGTGACCCTAGTATCAAGATTAA
TGATGATTCTAGTATTGAAGTTAATTCAGAACAAAACGCAAATGCAGAAGAAAAAGATATTACAGTAGATGTTAAATTTA
CTGTATATCCTGAAATTGAAATTCCTGATTTTAGTCAAATTACACTTAAGAAGCATGTAATACAGTGTACGGAAGAATCT
GTAAATGAGTTTATTAATGGGTTACGCCATGAAGTGTATGAATATAAGGATTGCTCAGAGCAAGAGAAAGCTATTAAGGG
AAGTAAGTTAGTTATAGATATTGCTATTACTGGTGATGGAATAGAAGATCATAATAAAGAAGATATAGAATTTATATTAG
GAAGTGGAAAGTTAATTAGTAAAGATATAGAGGAAAGATTTACTGACAGTATAGTAGGATCTCAGCTGGACATAAGTACA
ACTTTGCCAGATAATTATCCTGATAGTAAAGCTGCCGGTAAGCTGGCCAATTTAAGAGTTACAGTAAAAAAGATTCAACA
ACCTGTACTTATTACTGAGCAACAAATATTAGATAAATATAAAGTTACGAGTATAGATGAGCTGAAAGTCAAAGTAAAAG
AACTTCAGAATAAGGAATTTATGGGGCTTAGTCAAATATTACTAAGAGCCAGGCTTTTGAATCAGTTGGATAAGATGCTA
GATTATGATCTGCCTAAGCAACTATTAAAATCAGAGTATGCTGTTGTTAGGCAGAATGTTTTGGCTGCATTGAAGGATAA
TAATAATAATGGTATTAAGGTTGCTTTAGATAAAAGTTCTGATCATGATATTGAACAATATTGTCAATTTGTAGCTACTA
GAAGAGTAAGAATAGGTTTATTTGTATTACATTATGCTGATAAGAAAAATATTACTGTTACTGACGAAGAAAAAAATATG
CTTTTACTGCAATATTTAAATAAAGGTAAAGAAGAAGCAAATGCAATTGTGTATGCATATAATAATAACCTTAGATGGCT
ATCGAATAGCATAGCTATGGAAGCTAAGGAAATCAAGGTAATTAATCATATTCTTGAAAATGAAGTTCAAATTATAGAAG
AACCTTGTACATCTGATGAAATAGAAGGTTTCGCAGACGAAATAAGTAAGGATATGGGGTTAAGTTTTACTGATGATGCT
ATAAGCGAAAATATTAATAATGATTGTTAA

Upstream 100 bases:

>100_bases
TAGGTTCTGGCGCCGAAAGGCATGGGGGTTCAATTCCCTCCACCCGTACCAGCAAGCTTAAAAGAATGTAATTTACAAAA
TACTAAAGATTTAATTATTT

Downstream 100 bases:

>100_bases
GAGAGATGCTACAGTTGATTAATACCATCCAAGTAATATAAGCTAGATTGTGTTATATAAATTACAGTTTGATAGATAAA
AGAACAAAATATAGTAAGAA

Product: trigger factor

Products: peptidylproline (w =0) [C]

Alternate protein names: TF [H]

Number of amino acids: Translated: 489; Mature: 488

Protein sequence:

>489_residues
MSQIIELQSEGLEKHFQISIPASVIKDKTDQKVISLTARANMPGFRKFKSGSHITSKAMQVKQMQVRRQYEASIRNDVQN
DVIVAAVESLIKSNNFSLIGDPSIKINDDSSIEVNSEQNANAEEKDITVDVKFTVYPEIEIPDFSQITLKKHVIQCTEES
VNEFINGLRHEVYEYKDCSEQEKAIKGSKLVIDIAITGDGIEDHNKEDIEFILGSGKLISKDIEERFTDSIVGSQLDIST
TLPDNYPDSKAAGKLANLRVTVKKIQQPVLITEQQILDKYKVTSIDELKVKVKELQNKEFMGLSQILLRARLLNQLDKML
DYDLPKQLLKSEYAVVRQNVLAALKDNNNNGIKVALDKSSDHDIEQYCQFVATRRVRIGLFVLHYADKKNITVTDEEKNM
LLLQYLNKGKEEANAIVYAYNNNLRWLSNSIAMEAKEIKVINHILENEVQIIEEPCTSDEIEGFADEISKDMGLSFTDDA
ISENINNDC

Sequences:

>Translated_489_residues
MSQIIELQSEGLEKHFQISIPASVIKDKTDQKVISLTARANMPGFRKFKSGSHITSKAMQVKQMQVRRQYEASIRNDVQN
DVIVAAVESLIKSNNFSLIGDPSIKINDDSSIEVNSEQNANAEEKDITVDVKFTVYPEIEIPDFSQITLKKHVIQCTEES
VNEFINGLRHEVYEYKDCSEQEKAIKGSKLVIDIAITGDGIEDHNKEDIEFILGSGKLISKDIEERFTDSIVGSQLDIST
TLPDNYPDSKAAGKLANLRVTVKKIQQPVLITEQQILDKYKVTSIDELKVKVKELQNKEFMGLSQILLRARLLNQLDKML
DYDLPKQLLKSEYAVVRQNVLAALKDNNNNGIKVALDKSSDHDIEQYCQFVATRRVRIGLFVLHYADKKNITVTDEEKNM
LLLQYLNKGKEEANAIVYAYNNNLRWLSNSIAMEAKEIKVINHILENEVQIIEEPCTSDEIEGFADEISKDMGLSFTDDA
ISENINNDC
>Mature_488_residues
SQIIELQSEGLEKHFQISIPASVIKDKTDQKVISLTARANMPGFRKFKSGSHITSKAMQVKQMQVRRQYEASIRNDVQND
VIVAAVESLIKSNNFSLIGDPSIKINDDSSIEVNSEQNANAEEKDITVDVKFTVYPEIEIPDFSQITLKKHVIQCTEESV
NEFINGLRHEVYEYKDCSEQEKAIKGSKLVIDIAITGDGIEDHNKEDIEFILGSGKLISKDIEERFTDSIVGSQLDISTT
LPDNYPDSKAAGKLANLRVTVKKIQQPVLITEQQILDKYKVTSIDELKVKVKELQNKEFMGLSQILLRARLLNQLDKMLD
YDLPKQLLKSEYAVVRQNVLAALKDNNNNGIKVALDKSSDHDIEQYCQFVATRRVRIGLFVLHYADKKNITVTDEEKNML
LLQYLNKGKEEANAIVYAYNNNLRWLSNSIAMEAKEIKVINHILENEVQIIEEPCTSDEIEGFADEISKDMGLSFTDDAI
SENINNDC

Specific function: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation [H]

COG id: COG0544

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Escherichia coli, GI1786640, Length=447, Percent_Identity=24.6085011185682, Blast_Score=102, Evalue=5e-23,

Paralogues:

None

Copy number: 1070 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 500 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 340 Molecules/Cell In: Growth-Phase, Mini

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179
- InterPro:   IPR005215
- InterPro:   IPR008880
- InterPro:   IPR008881 [H]

Pfam domain/function: PF00254 FKBP_C; PF05698 Trigger_C; PF05697 Trigger_N [H]

EC number: NA

Molecular weight: Translated: 55353; Mature: 55221

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQIIELQSEGLEKHFQISIPASVIKDKTDQKVISLTARANMPGFRKFKSGSHITSKAMQ
CCHHHHHHHCCCCCEEEEECCHHHHCCCCCCCEEEEEECCCCCCHHHHCCCCHHHHHHHH
VKQMQVRRQYEASIRNDVQNDVIVAAVESLIKSNNFSLIGDPSIKINDDSSIEVNSEQNA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEECCCCCEEECCCCCC
NAEEKDITVDVKFTVYPEIEIPDFSQITLKKHVIQCTEESVNEFINGLRHEVYEYKDCSE
CCCCCCEEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
QEKAIKGSKLVIDIAITGDGIEDHNKEDIEFILGSGKLISKDIEERFTDSIVGSQLDIST
HHHHCCCCEEEEEEEEECCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCEEEEE
TLPDNYPDSKAAGKLANLRVTVKKIQQPVLITEQQILDKYKVTSIDELKVKVKELQNKEF
CCCCCCCCCHHHCCHHHHEEEHHHHCCCCEECHHHHHHHHCCCCHHHHHHHHHHHCCCCC
MGLSQILLRARLLNQLDKMLDYDLPKQLLKSEYAVVRQNVLAALKDNNNNGIKVALDKSS
CCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCC
DHDIEQYCQFVATRRVRIGLFVLHYADKKNITVTDEEKNMLLLQYLNKGKEEANAIVYAY
CCCHHHHHHHHHHHHHEEEEEEEEECCCCCEEEECCCCCCHHHHHHHCCCHHCCEEEEEE
NNNLRWLSNSIAMEAKEIKVINHILENEVQIIEEPCTSDEIEGFADEISKDMGLSFTDDA
ECCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCHH
ISENINNDC
HHHCCCCCC
>Mature Secondary Structure 
SQIIELQSEGLEKHFQISIPASVIKDKTDQKVISLTARANMPGFRKFKSGSHITSKAMQ
CHHHHHHHCCCCCEEEEECCHHHHCCCCCCCEEEEEECCCCCCHHHHCCCCHHHHHHHH
VKQMQVRRQYEASIRNDVQNDVIVAAVESLIKSNNFSLIGDPSIKINDDSSIEVNSEQNA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEECCCCCEEECCCCCC
NAEEKDITVDVKFTVYPEIEIPDFSQITLKKHVIQCTEESVNEFINGLRHEVYEYKDCSE
CCCCCCEEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
QEKAIKGSKLVIDIAITGDGIEDHNKEDIEFILGSGKLISKDIEERFTDSIVGSQLDIST
HHHHCCCCEEEEEEEEECCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCEEEEE
TLPDNYPDSKAAGKLANLRVTVKKIQQPVLITEQQILDKYKVTSIDELKVKVKELQNKEF
CCCCCCCCCHHHCCHHHHEEEHHHHCCCCEECHHHHHHHHCCCCHHHHHHHHHHHCCCCC
MGLSQILLRARLLNQLDKMLDYDLPKQLLKSEYAVVRQNVLAALKDNNNNGIKVALDKSS
CCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCC
DHDIEQYCQFVATRRVRIGLFVLHYADKKNITVTDEEKNMLLLQYLNKGKEEANAIVYAY
CCCHHHHHHHHHHHHHEEEEEEEEECCCCCEEEECCCCCCHHHHHHHCCCHHCCEEEEEE
NNNLRWLSNSIAMEAKEIKVINHILENEVQIIEEPCTSDEIEGFADEISKDMGLSFTDDA
ECCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCHH
ISENINNDC
HHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: peptidylproline (w =180) [C]

Specific reaction: peptidylproline (w =180) = peptidylproline (w =0) [C]

General reaction: Isomerases; cis-trans-Isomerases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA