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The map label for this gene is iscR [H]

Identifier: 189183482

GI number: 189183482

Start: 587565

End: 588011

Strand: Reverse

Name: iscR [H]

Synonym: OTT_0575

Alternate gene names: 189183482

Gene position: 588011-587565 (Counterclockwise)

Preceding gene: 189183488

Following gene: 189183481

Centisome position: 29.27

GC content: 30.2

Gene sequence:

>447_bases
TTGATATTAACCACTAAAAGCAAATATGCTGTTATGGGAGTGCTAGATATTGCAAGTAGAGAGTCAAGCAAACCAGCTAA
ATTATTTGAAATTGCCAAGCGTCAGAATATAGCGCTCAATTACTTAGAGCAACTATTCAATAAACTTAAAAATAAGGGGA
TAGTAAAATCAGTTAAAGGCCCAAACGGAGGTTATTTATTAAGCTGCGATATAAAAAAAACGACTATTAATGATATTATT
TTTGCTGTTGAAGAAAAAATTCAAATTACTAGATGTAATAATAGCAAAGGATGTTTAGCATTAAATGTTAGATGTACTGC
TCACTATTTGTGGGAAGAATTAGAATATAAAATTAAACACTACTTTAGTGAAATCTCTTTGGATGATATAATTTCCGGGA
AAGTAAAGTCACAAGCTTTAAAAGCAAGATCACTTAGGTTAAATTGA

Upstream 100 bases:

>100_bases
TAATAATTAGATGTTTGCTTAGTTATAGCAAATATTTTTTAGTCTAGTTTATTTAGAATTTTTTCTATATACCAAAATAA
CACAAGAGGTTGTAAGTCTA

Downstream 100 bases:

>100_bases
ATGGCTGAGTAATGTATAACTTTATTGATCATAGCACTGCAGCAGCTATTGAAAATTCAGCTAGATATTATAATTCTACT
GATAGGCCTTCTTTTTCTAG

Product: Rrf2 family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 148; Mature: 148

Protein sequence:

>148_residues
MILTTKSKYAVMGVLDIASRESSKPAKLFEIAKRQNIALNYLEQLFNKLKNKGIVKSVKGPNGGYLLSCDIKKTTINDII
FAVEEKIQITRCNNSKGCLALNVRCTAHYLWEELEYKIKHYFSEISLDDIISGKVKSQALKARSLRLN

Sequences:

>Translated_148_residues
MILTTKSKYAVMGVLDIASRESSKPAKLFEIAKRQNIALNYLEQLFNKLKNKGIVKSVKGPNGGYLLSCDIKKTTINDII
FAVEEKIQITRCNNSKGCLALNVRCTAHYLWEELEYKIKHYFSEISLDDIISGKVKSQALKARSLRLN
>Mature_148_residues
MILTTKSKYAVMGVLDIASRESSKPAKLFEIAKRQNIALNYLEQLFNKLKNKGIVKSVKGPNGGYLLSCDIKKTTINDII
FAVEEKIQITRCNNSKGCLALNVRCTAHYLWEELEYKIKHYFSEISLDDIISGKVKSQALKARSLRLN

Specific function: Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins [H]

COG id: COG1959

COG function: function code K; Predicted transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH rrf2-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788880, Length=131, Percent_Identity=38.1679389312977, Blast_Score=108, Evalue=1e-25,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010242
- InterPro:   IPR000944
- InterPro:   IPR011991 [H]

Pfam domain/function: PF02082 Rrf2 [H]

EC number: NA

Molecular weight: Translated: 16756; Mature: 16756

Theoretical pI: Translated: 10.09; Mature: 10.09

Prosite motif: PS01332 UPF0074

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILTTKSKYAVMGVLDIASRESSKPAKLFEIAKRQNIALNYLEQLFNKLKNKGIVKSVKG
CEEECCCCEEEEEHHHHHCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEECCC
PNGGYLLSCDIKKTTINDIIFAVEEKIQITRCNNSKGCLALNVRCTAHYLWEELEYKIKH
CCCCEEEEECCCHHHHHHHHHHHHCCEEEEEECCCCCEEEEEEEHHHHHHHHHHHHHHHH
YFSEISLDDIISGKVKSQALKARSLRLN
HHHHCCHHHHHCCHHHHHHHHHHHCCCC
>Mature Secondary Structure
MILTTKSKYAVMGVLDIASRESSKPAKLFEIAKRQNIALNYLEQLFNKLKNKGIVKSVKG
CEEECCCCEEEEEHHHHHCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEECCC
PNGGYLLSCDIKKTTINDIIFAVEEKIQITRCNNSKGCLALNVRCTAHYLWEELEYKIKH
CCCCEEEEECCCHHHHHHHHHHHHCCEEEEEECCCCCEEEEEEEHHHHHHHHHHHHHHHH
YFSEISLDDIISGKVKSQALKARSLRLN
HHHHCCHHHHHCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]