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The map label for this gene is iscU [H]

Identifier: 189183479

GI number: 189183479

Start: 584516

End: 584941

Strand: Reverse

Name: iscU [H]

Synonym: OTT_0572

Alternate gene names: 189183479

Gene position: 584941-584516 (Counterclockwise)

Preceding gene: 189183480

Following gene: 189183478

Centisome position: 29.12

GC content: 34.04

Gene sequence:

>426_bases
ATGAATAATGATGAAAAAACAGTTACAGGTACTCGTACAGCTGGTTATAGTTCAGAAGTTATAAAGTACTATGAAGATAG
ATCTAATGTTGGATCACTTGATGAAACAGATAAATCAGTTGGTACTGGATTAGTTGGTGCTCCTGCTTGCGGCGATGTTA
TGAAACTGCAAATTAAAGTAAATGATCACGGAATAATTGAAGATGCAAAATTTAAGACTTTTGGCTGTGGATCAGCAATA
GCTTCAAGCGCTTTAGTTACTGAATGGATAAAATCTCAATCTTTAAGTGATGCAGAGCAAATTAAAAATAGTCAGATTGC
TGAGCATTTAGCATTGCTACCAATTAAAATGCATTGCTCAATGTTAGCTGAAGATGCTATTAAGGCGGCTATTGTTGATT
ACAAGTCTAAGCAAAATAAAACATAA

Upstream 100 bases:

>100_bases
ACTTTGGGAAATGACACAAAAAGGAATAGATATAAAACAAATTAATTGGTCAGTGCATTAAGCAACTAATTAACTACAAT
CGATAAGAGGAAAAAATATT

Downstream 100 bases:

>100_bases
ATTTTTATTATGAATGCTATTAATTCTTCACAACTACAAATTAATAAAGCTCGTAAGCAAGTTATTACTATTTCAAGTCG
AGCAGCTAAAAGAATTAAAG

Product: NifU protein homolog

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 141; Mature: 141

Protein sequence:

>141_residues
MNNDEKTVTGTRTAGYSSEVIKYYEDRSNVGSLDETDKSVGTGLVGAPACGDVMKLQIKVNDHGIIEDAKFKTFGCGSAI
ASSALVTEWIKSQSLSDAEQIKNSQIAEHLALLPIKMHCSMLAEDAIKAAIVDYKSKQNKT

Sequences:

>Translated_141_residues
MNNDEKTVTGTRTAGYSSEVIKYYEDRSNVGSLDETDKSVGTGLVGAPACGDVMKLQIKVNDHGIIEDAKFKTFGCGSAI
ASSALVTEWIKSQSLSDAEQIKNSQIAEHLALLPIKMHCSMLAEDAIKAAIVDYKSKQNKT
>Mature_141_residues
MNNDEKTVTGTRTAGYSSEVIKYYEDRSNVGSLDETDKSVGTGLVGAPACGDVMKLQIKVNDHGIIEDAKFKTFGCGSAI
ASSALVTEWIKSQSLSDAEQIKNSQIAEHLALLPIKMHCSMLAEDAIKAAIVDYKSKQNKT

Specific function: May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins (Potential) [H]

COG id: COG0822

COG function: function code C; NifU homolog involved in Fe-S cluster formation

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nifU family [H]

Homologues:

Organism=Homo sapiens, GI56699456, Length=123, Percent_Identity=66.6666666666667, Blast_Score=178, Evalue=1e-45,
Organism=Homo sapiens, GI24307953, Length=122, Percent_Identity=67.2131147540984, Blast_Score=177, Evalue=3e-45,
Organism=Escherichia coli, GI1788878, Length=123, Percent_Identity=71.5447154471545, Blast_Score=191, Evalue=2e-50,
Organism=Caenorhabditis elegans, GI17543474, Length=131, Percent_Identity=63.3587786259542, Blast_Score=176, Evalue=3e-45,
Organism=Saccharomyces cerevisiae, GI6325122, Length=125, Percent_Identity=67.2, Blast_Score=177, Evalue=5e-46,
Organism=Saccharomyces cerevisiae, GI6324800, Length=142, Percent_Identity=60.5633802816901, Blast_Score=171, Evalue=5e-44,
Organism=Drosophila melanogaster, GI21355597, Length=135, Percent_Identity=64.4444444444444, Blast_Score=183, Evalue=2e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011339
- InterPro:   IPR002871 [H]

Pfam domain/function: PF01592 NifU_N [H]

EC number: NA

Molecular weight: Translated: 15186; Mature: 15186

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNDEKTVTGTRTAGYSSEVIKYYEDRSNVGSLDETDKSVGTGLVGAPACGDVMKLQIKV
CCCCCCEEECCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCCCCCCCEEEEEEEE
NDHGIIEDAKFKTFGCGSAIASSALVTEWIKSQSLSDAEQIKNSQIAEHLALLPIKMHCS
CCCCCEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
MLAEDAIKAAIVDYKSKQNKT
HHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MNNDEKTVTGTRTAGYSSEVIKYYEDRSNVGSLDETDKSVGTGLVGAPACGDVMKLQIKV
CCCCCCEEECCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCCCCCCCEEEEEEEE
NDHGIIEDAKFKTFGCGSAIASSALVTEWIKSQSLSDAEQIKNSQIAEHLALLPIKMHCS
CCCCCEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
MLAEDAIKAAIVDYKSKQNKT
HHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]