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The map label for this gene is ilvE [H]

Identifier: 189182989

GI number: 189182989

Start: 87475

End: 88377

Strand: Direct

Name: ilvE [H]

Synonym: OTT_0082

Alternate gene names: 189182989

Gene position: 87475-88377 (Clockwise)

Preceding gene: 189182988

Following gene: 189182990

Centisome position: 4.35

GC content: 28.9

Gene sequence:

>903_bases
ATGTTAAACTTTTATTTTAATAATGCTAATTATTTATGGATAAATAATGAATTTGTAGAGTGGAAAACAGCTAACGTCCA
TTTAATGACACATAGTTTACACTACGCTAGTTCAGTATTTGAAGGTATTAGAACATATAATGGCAAAGCTTTTAAACTAG
AAGAACATATTGATCGTCTATTTGATTCAGCTCAACAATTAATGATACCAGTAAAGTATAGTAAATCTGATATTATTATA
GCATGTAAAGCCTTAATAGAGAAAAATAATCTTACTAATGCTTATATTAGGCCACTAATATGGAAAGGAGCGGAATCATC
AAGATTAATATCTCCATTGTTATCTACTAATGTTATGCTTGCAGGTTGGGAAATACCTAAGCGGACACAGCAACCTATGA
ATTTATGTTTTAGTAATTGGATTAATATTCCTCCGCAAACTATTCCAATTCAGTGTAAGTCTGGAGGACGTTATACTACA
ATGATAATTAGCAAAACAGAAAGTGAGAATCAGGGATTTGATGATGCTATTTTATTAGATTGGCGTGGTTATATTTCTGA
AGCTACTACATCTAATATTTTTTTTGTTGCTCATGATAAAATTATTACACCAATAGCAGATGCTTGTTTGAATGGTATTA
CTAGGCAAACAGTATTTGCGATTGCTAAAAAGTTAGGTATAATAGCTGAGGAACAATATATTAAGCCTGAATTTTTAATA
GATTATCAAGCGTGTTTTTTAGTTGGAACATCTATTGAAATTAGAGAAGTAAATGTAATTAATTTTACTGCACTTAAAAA
TCATAATCTGCAAGTTGAAAAGATTTATGATCTTGATAATTCAGTTACTAGTGTTATAAAAAACTATTATAATAAGTTAG
TTAATGACGAAGAAGATGTTTAA

Upstream 100 bases:

>100_bases
AAATCTTATGATGCTATTGTCGCTTTTTCTATGCTCAAACTACTTCATTGTAAATTACTATACTACATTCTATAATATAT
TAACTTTATGAGCTAATGTA

Downstream 100 bases:

>100_bases
TGGACTAATTACTGCTTTAGTTACTCCTTTTAAAAATGCTGCAAAGCAGATTGATTTTTGTGCATTAGAGAAATTATTAG
ATTTACAAATTAAAGCTCAA

Product: branched-chain amino acid aminotransferase

Products: NA

Alternate protein names: BCAT [H]

Number of amino acids: Translated: 300; Mature: 300

Protein sequence:

>300_residues
MLNFYFNNANYLWINNEFVEWKTANVHLMTHSLHYASSVFEGIRTYNGKAFKLEEHIDRLFDSAQQLMIPVKYSKSDIII
ACKALIEKNNLTNAYIRPLIWKGAESSRLISPLLSTNVMLAGWEIPKRTQQPMNLCFSNWINIPPQTIPIQCKSGGRYTT
MIISKTESENQGFDDAILLDWRGYISEATTSNIFFVAHDKIITPIADACLNGITRQTVFAIAKKLGIIAEEQYIKPEFLI
DYQACFLVGTSIEIREVNVINFTALKNHNLQVEKIYDLDNSVTSVIKNYYNKLVNDEEDV

Sequences:

>Translated_300_residues
MLNFYFNNANYLWINNEFVEWKTANVHLMTHSLHYASSVFEGIRTYNGKAFKLEEHIDRLFDSAQQLMIPVKYSKSDIII
ACKALIEKNNLTNAYIRPLIWKGAESSRLISPLLSTNVMLAGWEIPKRTQQPMNLCFSNWINIPPQTIPIQCKSGGRYTT
MIISKTESENQGFDDAILLDWRGYISEATTSNIFFVAHDKIITPIADACLNGITRQTVFAIAKKLGIIAEEQYIKPEFLI
DYQACFLVGTSIEIREVNVINFTALKNHNLQVEKIYDLDNSVTSVIKNYYNKLVNDEEDV
>Mature_300_residues
MLNFYFNNANYLWINNEFVEWKTANVHLMTHSLHYASSVFEGIRTYNGKAFKLEEHIDRLFDSAQQLMIPVKYSKSDIII
ACKALIEKNNLTNAYIRPLIWKGAESSRLISPLLSTNVMLAGWEIPKRTQQPMNLCFSNWINIPPQTIPIQCKSGGRYTT
MIISKTESENQGFDDAILLDWRGYISEATTSNIFFVAHDKIITPIADACLNGITRQTVFAIAKKLGIIAEEQYIKPEFLI
DYQACFLVGTSIEIREVNVINFTALKNHNLQVEKIYDLDNSVTSVIKNYYNKLVNDEEDV

Specific function: Acts on leucine, isoleucine and valine [H]

COG id: COG0115

COG function: function code EH; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Escherichia coli, GI48994963, Length=266, Percent_Identity=38.3458646616541, Blast_Score=186, Evalue=2e-48,

Paralogues:

None

Copy number: 2342 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 11,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001544
- InterPro:   IPR018300 [H]

Pfam domain/function: PF01063 Aminotran_4 [H]

EC number: =2.6.1.42 [H]

Molecular weight: Translated: 34381; Mature: 34381

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS00770 AA_TRANSFER_CLASS_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNFYFNNANYLWINNEFVEWKTANVHLMTHSLHYASSVFEGIRTYNGKAFKLEEHIDRL
CEEEEEECEEEEEEECCEEEEEECEEEEEEEHHHHHHHHHHHHHHCCCCEEEHHHHHHHH
FDSAQQLMIPVKYSKSDIIIACKALIEKNNLTNAYIRPLIWKGAESSRLISPLLSTNVML
HHHHHHEEEEEEECCCCEEEEEEHHHHCCCCCHHHHHHEEECCCCCCHHHHHHHHCCEEE
AGWEIPKRTQQPMNLCFSNWINIPPQTIPIQCKSGGRYTTMIISKTESENQGFDDAILLD
EECCCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEEEEEECCCCCCCCCCEEEEE
WRGYISEATTSNIFFVAHDKIITPIADACLNGITRQTVFAIAKKLGIIAEEQYIKPEFLI
CCHHHCCCCCCCEEEEECCCCHHHHHHHHHCCHHHHHHHHHHHHHCCEEHHCCCCCCEEE
DYQACFLVGTSIEIREVNVINFTALKNHNLQVEKIYDLDNSVTSVIKNYYNKLVNDEEDV
EEEEEEEECCCEEEEEEEEEEEEEEECCCEEEEEEECCCHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MLNFYFNNANYLWINNEFVEWKTANVHLMTHSLHYASSVFEGIRTYNGKAFKLEEHIDRL
CEEEEEECEEEEEEECCEEEEEECEEEEEEEHHHHHHHHHHHHHHCCCCEEEHHHHHHHH
FDSAQQLMIPVKYSKSDIIIACKALIEKNNLTNAYIRPLIWKGAESSRLISPLLSTNVML
HHHHHHEEEEEEECCCCEEEEEEHHHHCCCCCHHHHHHEEECCCCCCHHHHHHHHCCEEE
AGWEIPKRTQQPMNLCFSNWINIPPQTIPIQCKSGGRYTTMIISKTESENQGFDDAILLD
EECCCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEEEEEECCCCCCCCCCEEEEE
WRGYISEATTSNIFFVAHDKIITPIADACLNGITRQTVFAIAKKLGIIAEEQYIKPEFLI
CCHHHCCCCCCCEEEEECCCCHHHHHHHHHCCHHHHHHHHHHHHHCCEEHHCCCCCCEEE
DYQACFLVGTSIEIREVNVINFTALKNHNLQVEKIYDLDNSVTSVIKNYYNKLVNDEEDV
EEEEEEEECCCEEEEEEEEEEEEEEECCCEEEEEEECCCHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA