Click here to switch to the map view.

The map label for this gene is xerD [H]

Identifier: 189182982

GI number: 189182982

Start: 77941

End: 78870

Strand: Reverse

Name: xerD [H]

Synonym: OTT_0075

Alternate gene names: 189182982

Gene position: 78870-77941 (Counterclockwise)

Preceding gene: 189183023

Following gene: 189182981

Centisome position: 3.93

GC content: 32.58

Gene sequence:

>930_bases
ATGGACTTCTTAGAACAATTCCTTGAGACTGTTTTAGCTGAGAAAAATGTTTCAGCAAATTCTTTATTGGCATATAAGCG
CGATCTGCAAGATTTTAATGATTTTCTTAAAAGTATTCAGCTACAAAGCTCGCTAGCTGTTACTAACAATGATATTGATT
CTTTTATTCAACATCTTCTTGGTAAAAATCTTAGTTTTAGATCTATTGCACGGAAGATATCTACTTTAAGGCAGTACTAT
TTGTTTTTGTTAACAGAAAATGCAGTTCAAGCTGACTTAGTGACTAATATTGAAGTGCCGCGTTATAGCACAAAATTGCC
AAAAATATTATCTATTAAAGAAATCAAAGTGCTAATTGATTATTGTTTCAAAGATACTACTGCTGAAGGTATACGTACAT
TAGCGATGATTTGCTTGCTATATTCTACTGGTCTTAGAGTATCAGAATTAGTTAGTGTGAAAATTACTGACTTAAAATTT
GATCACAATACAGGCAAAATCAAGAATCATTTTGTAATTTTGGGAAAAGGGAATAAAGAAAGATTAGTTATTATGAATGA
TCTTACTGGCGATGTAATATCTAAATATTTACCTTATCGAGATTTTTTTTCTCCATTCAAAAATGCTAAGAATAGTGTTT
ATCTTTTTCCATCAAAGGCTAAGCAAGGATATATGACGCGGCAAAATTTTGCTATACTACTTAAACATGCTGCTATCAAT
GCTGGTCTTTCGCCTGATAATGTTTCTCCGCATATATTGCGGCATAGCTTTGCAAGTCATTTGCTTGAAGGTGGAGCAGA
TTTAAAGGTTATTCAAGAGCTGCTAGGGCATGTTGATATTAGTTCTACTCAGATTTATACTCACGTGCAGCCAGAAAGGT
TAAAGCATGTAATAGAGAAATATCATCCAGCCAGCTTAAAAAAGTATTAA

Upstream 100 bases:

>100_bases
CCGGCCCTGGCCTCCATTGCTTGCTTGTGACTAGTCTATCTGATAATATTATCTGATAATATTAATAGACAGATTAATCA
AGTTAAGTATAAAGAAAATT

Downstream 100 bases:

>100_bases
ATATATATTTAATACTTTAGTTCGTTAATGATATGAAGTTATCAGGAAAACATGATACTGGAAGTCCATACGTTATATTT
GATGTCGCGTGTGATGGAAA

Product: site-specific tyrosine recombinase XerD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 309; Mature: 309

Protein sequence:

>309_residues
MDFLEQFLETVLAEKNVSANSLLAYKRDLQDFNDFLKSIQLQSSLAVTNNDIDSFIQHLLGKNLSFRSIARKISTLRQYY
LFLLTENAVQADLVTNIEVPRYSTKLPKILSIKEIKVLIDYCFKDTTAEGIRTLAMICLLYSTGLRVSELVSVKITDLKF
DHNTGKIKNHFVILGKGNKERLVIMNDLTGDVISKYLPYRDFFSPFKNAKNSVYLFPSKAKQGYMTRQNFAILLKHAAIN
AGLSPDNVSPHILRHSFASHLLEGGADLKVIQELLGHVDISSTQIYTHVQPERLKHVIEKYHPASLKKY

Sequences:

>Translated_309_residues
MDFLEQFLETVLAEKNVSANSLLAYKRDLQDFNDFLKSIQLQSSLAVTNNDIDSFIQHLLGKNLSFRSIARKISTLRQYY
LFLLTENAVQADLVTNIEVPRYSTKLPKILSIKEIKVLIDYCFKDTTAEGIRTLAMICLLYSTGLRVSELVSVKITDLKF
DHNTGKIKNHFVILGKGNKERLVIMNDLTGDVISKYLPYRDFFSPFKNAKNSVYLFPSKAKQGYMTRQNFAILLKHAAIN
AGLSPDNVSPHILRHSFASHLLEGGADLKVIQELLGHVDISSTQIYTHVQPERLKHVIEKYHPASLKKY
>Mature_309_residues
MDFLEQFLETVLAEKNVSANSLLAYKRDLQDFNDFLKSIQLQSSLAVTNNDIDSFIQHLLGKNLSFRSIARKISTLRQYY
LFLLTENAVQADLVTNIEVPRYSTKLPKILSIKEIKVLIDYCFKDTTAEGIRTLAMICLLYSTGLRVSELVSVKITDLKF
DHNTGKIKNHFVILGKGNKERLVIMNDLTGDVISKYLPYRDFFSPFKNAKNSVYLFPSKAKQGYMTRQNFAILLKHAAIN
AGLSPDNVSPHILRHSFASHLLEGGADLKVIQELLGHVDISSTQIYTHVQPERLKHVIEKYHPASLKKY

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=300, Percent_Identity=38, Blast_Score=192, Evalue=2e-50,
Organism=Escherichia coli, GI1790244, Length=300, Percent_Identity=32.6666666666667, Blast_Score=152, Evalue=3e-38,
Organism=Escherichia coli, GI1790768, Length=197, Percent_Identity=27.4111675126904, Blast_Score=72, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 35166; Mature: 35166

Theoretical pI: Translated: 9.74; Mature: 9.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFLEQFLETVLAEKNVSANSLLAYKRDLQDFNDFLKSIQLQSSLAVTNNDIDSFIQHLL
CCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHH
GKNLSFRSIARKISTLRQYYLFLLTENAVQADLVTNIEVPRYSTKLPKILSIKEIKVLID
CCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHH
YCFKDTTAEGIRTLAMICLLYSTGLRVSELVSVKITDLKFDHNTGKIKNHFVILGKGNKE
HHHCCCHHHHHHHHHHHHHHHHCCCCHHHHEEEEEEEEEEECCCCCCCCEEEEEECCCCC
RLVIMNDLTGDVISKYLPYRDFFSPFKNAKNSVYLFPSKAKQGYMTRQNFAILLKHAAIN
EEEEEECCCHHHHHHHCCHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHH
AGLSPDNVSPHILRHSFASHLLEGGADLKVIQELLGHVDISSTQIYTHVQPERLKHVIEK
CCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHH
YHPASLKKY
CCCCCCCCC
>Mature Secondary Structure
MDFLEQFLETVLAEKNVSANSLLAYKRDLQDFNDFLKSIQLQSSLAVTNNDIDSFIQHLL
CCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHH
GKNLSFRSIARKISTLRQYYLFLLTENAVQADLVTNIEVPRYSTKLPKILSIKEIKVLID
CCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHH
YCFKDTTAEGIRTLAMICLLYSTGLRVSELVSVKITDLKFDHNTGKIKNHFVILGKGNKE
HHHCCCHHHHHHHHHHHHHHHHCCCCHHHHEEEEEEEEEEECCCCCCCCEEEEEECCCCC
RLVIMNDLTGDVISKYLPYRDFFSPFKNAKNSVYLFPSKAKQGYMTRQNFAILLKHAAIN
EEEEEECCCHHHHHHHCCHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHH
AGLSPDNVSPHILRHSFASHLLEGGADLKVIQELLGHVDISSTQIYTHVQPERLKHVIEK
CCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHH
YHPASLKKY
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9823893 [H]