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The map label for this gene is hupA [H]

Identifier: 189182932

GI number: 189182932

Start: 31920

End: 32228

Strand: Direct

Name: hupA [H]

Synonym: OTT_0025

Alternate gene names: 189182932

Gene position: 31920-32228 (Clockwise)

Preceding gene: 189182931

Following gene: 189182933

Centisome position: 1.59

GC content: 31.39

Gene sequence:

>309_bases
ATGAGCACAAATAATCAAGAAAGAGAAGCGCTAAACAAAGCTGAATTTGTAAATTTTATACATAAAAATAATACAAATAT
GACTAAGGCTGATATAGAGCGAGCATTAAACTTAATATTGCGTGGCGTTGAAAAGGCTATTGAAAACGGTCATGATATAA
ATATTGTAGGCTTTGGAAGCTTTTGTGTAAGATTTAGAGCAGCAAGAGATGGACACAATCCTAAAACTGGGGCTAAAATT
ATTATTCCTGAAAGTTATCAGGTAGTTTTTAAACCAGGTAAAACCTTAAAAGATGCATGTAATAATTAA

Upstream 100 bases:

>100_bases
ATCATTAATAATGCAAACTATTTGTATAATTAGTTAGATGTTTAGTTATATTGGTACAATGTAACTTTTATTATTATTTT
ATTATTATTTAAGGAGATTT

Downstream 100 bases:

>100_bases
ATGCATTGCTGCTTGTTATTTGATTTTATAGCTTGTAAGTTATTGTATATAATTGCAGGTTATAGCAGGAATTGAAATGA
TAGTTAGGTAATAGTTTGCC

Product: DNA-binding protein HU

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 102; Mature: 101

Protein sequence:

>102_residues
MSTNNQEREALNKAEFVNFIHKNNTNMTKADIERALNLILRGVEKAIENGHDINIVGFGSFCVRFRAARDGHNPKTGAKI
IIPESYQVVFKPGKTLKDACNN

Sequences:

>Translated_102_residues
MSTNNQEREALNKAEFVNFIHKNNTNMTKADIERALNLILRGVEKAIENGHDINIVGFGSFCVRFRAARDGHNPKTGAKI
IIPESYQVVFKPGKTLKDACNN
>Mature_101_residues
STNNQEREALNKAEFVNFIHKNNTNMTKADIERALNLILRGVEKAIENGHDINIVGFGSFCVRFRAARDGHNPKTGAKII
IPESYQVVFKPGKTLKDACNN

Specific function: Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions [H]

COG id: COG0776

COG function: function code L; Bacterial nucleoid DNA-binding protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial histone-like protein family [H]

Homologues:

Organism=Escherichia coli, GI1786644, Length=91, Percent_Identity=40.6593406593407, Blast_Score=76, Evalue=4e-16,
Organism=Escherichia coli, GI1787141, Length=91, Percent_Identity=35.1648351648352, Blast_Score=68, Evalue=1e-13,
Organism=Escherichia coli, GI1788005, Length=93, Percent_Identity=35.4838709677419, Blast_Score=66, Evalue=4e-13,
Organism=Escherichia coli, GI1790433, Length=90, Percent_Identity=34.4444444444444, Blast_Score=60, Evalue=3e-11,

Paralogues:

None

Copy number: 860 Molecules/Cell In: Growth-Phase, Minimal Media (Based on E. coli). 2040 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000119
- InterPro:   IPR020816
- InterPro:   IPR010992 [H]

Pfam domain/function: PF00216 Bac_DNA_binding [H]

EC number: NA

Molecular weight: Translated: 11415; Mature: 11284

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: PS00045 HISTONE_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTNNQEREALNKAEFVNFIHKNNTNMTKADIERALNLILRGVEKAIENGHDINIVGFGS
CCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHH
FCVRFRAARDGHNPKTGAKIIIPESYQVVFKPGKTLKDACNN
HHHHHHHHCCCCCCCCCCEEEECCCEEEEECCCCHHHHHCCC
>Mature Secondary Structure 
STNNQEREALNKAEFVNFIHKNNTNMTKADIERALNLILRGVEKAIENGHDINIVGFGS
CCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHH
FCVRFRAARDGHNPKTGAKIIIPESYQVVFKPGKTLKDACNN
HHHHHHHHCCCCCCCCCCEEEECCCEEEEECCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA