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The map label for this gene is era [H]

Identifier: 189182921

GI number: 189182921

Start: 18946

End: 19866

Strand: Direct

Name: era [H]

Synonym: OTT_0014

Alternate gene names: 189182921

Gene position: 18946-19866 (Clockwise)

Preceding gene: 189182920

Following gene: 189182923

Centisome position: 0.94

GC content: 29.86

Gene sequence:

>921_bases
ATGACAGAGTCTAAAAATCGACTAGATAAACAACAAAAGACAATGGTTGTGAGCATATTGGGTATGCCAAACTCTGGTAA
GTCAACCTTACTAAATAGATTAATAGGACAAAAAATCTCTATTGTGACTCCAAAAGTCCAAACTACTAGATCTGCTATTA
CTGGGATTGTAACTTACAACCTTACACAATTGATTTTTATTGATACTCCTGGAATATTCCAACCTAAAAAAACATTAGAA
AAAGCAATGGTGCGCTGCGCATGGACAAGCATTGTTGGAGCAGATATAGCATTGTTGATAATAGATATTACTAAAAAATT
AAATGAGCAAATTCAAATTATTTTAACTAGATTAATATCACAAAAAATTAAGTTTTGCATTATTTTAAACAAAATTGATA
TTTGCGTAAATAACTTGACTCAGTTAATGAATGATCTAAAACAATTATCTATTAATGCTAAAATTATAGCAATATCTGCA
TTAAATGGAAATGGAGTACAAGAATTGCTTCAATATATATCTACTATAGCTCCTATTAGGCCTTGGTTATATGATGAAGA
TGATATTACTACTGCTAGTATGAAGTTTTTAGCTCAAGAAATTACTAGAGAGCAACTATTTTTAGCGCTACATCAGGAAT
TACCATATAATATAACAGTTGAGCATGAAAGATGGGAACAACTAAATGATGGCAGTGTTAAAATTTATCAAGCAATTGTA
GCCAATAAGGATAACTATAAAGCAATAATTCTTGGTAAAGCAGGCAGTAGAATCAAGAGTATTGGACAAAAGGCTAGATT
TGCTATGCAGAAAATTCTTAATCTTAAAGTATGCTTAATTTTATTTGTAAAAATAAGACCTACTTGGGACCAAGAATATA
GCTTTTATGAAAAGATGGGGTTAAAGTTAATAAAGTCATAA

Upstream 100 bases:

>100_bases
AAGAGCCAATTAAATTATCTTACGATCTACAATCCAAATTACTTACAGATGAGTTTTTTATTCTTGAGCTTTTTAACTTT
CAGGAAGGAAGTAATATTCA

Downstream 100 bases:

>100_bases
TATAACATAAGTGTGATATAAGATATGTTAGAGAAGAATAAGAGTTATAGCTCTTTTGAGCTTATATTTATATAGTTTTA
AACATATATTTTCATAATTC

Product: GTP-binding protein Era

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 305

Protein sequence:

>306_residues
MTESKNRLDKQQKTMVVSILGMPNSGKSTLLNRLIGQKISIVTPKVQTTRSAITGIVTYNLTQLIFIDTPGIFQPKKTLE
KAMVRCAWTSIVGADIALLIIDITKKLNEQIQIILTRLISQKIKFCIILNKIDICVNNLTQLMNDLKQLSINAKIIAISA
LNGNGVQELLQYISTIAPIRPWLYDEDDITTASMKFLAQEITREQLFLALHQELPYNITVEHERWEQLNDGSVKIYQAIV
ANKDNYKAIILGKAGSRIKSIGQKARFAMQKILNLKVCLILFVKIRPTWDQEYSFYEKMGLKLIKS

Sequences:

>Translated_306_residues
MTESKNRLDKQQKTMVVSILGMPNSGKSTLLNRLIGQKISIVTPKVQTTRSAITGIVTYNLTQLIFIDTPGIFQPKKTLE
KAMVRCAWTSIVGADIALLIIDITKKLNEQIQIILTRLISQKIKFCIILNKIDICVNNLTQLMNDLKQLSINAKIIAISA
LNGNGVQELLQYISTIAPIRPWLYDEDDITTASMKFLAQEITREQLFLALHQELPYNITVEHERWEQLNDGSVKIYQAIV
ANKDNYKAIILGKAGSRIKSIGQKARFAMQKILNLKVCLILFVKIRPTWDQEYSFYEKMGLKLIKS
>Mature_305_residues
TESKNRLDKQQKTMVVSILGMPNSGKSTLLNRLIGQKISIVTPKVQTTRSAITGIVTYNLTQLIFIDTPGIFQPKKTLEK
AMVRCAWTSIVGADIALLIIDITKKLNEQIQIILTRLISQKIKFCIILNKIDICVNNLTQLMNDLKQLSINAKIIAISAL
NGNGVQELLQYISTIAPIRPWLYDEDDITTASMKFLAQEITREQLFLALHQELPYNITVEHERWEQLNDGSVKIYQAIVA
NKDNYKAIILGKAGSRIKSIGQKARFAMQKILNLKVCLILFVKIRPTWDQEYSFYEKMGLKLIKS

Specific function: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism [H]

COG id: COG1159

COG function: function code R; GTPase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH type-2 domain [H]

Homologues:

Organism=Homo sapiens, GI24307899, Length=330, Percent_Identity=28.7878787878788, Blast_Score=119, Evalue=4e-27,
Organism=Escherichia coli, GI1788919, Length=288, Percent_Identity=34.375, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI87082120, Length=170, Percent_Identity=30, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI2367268, Length=165, Percent_Identity=30.3030303030303, Blast_Score=68, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6323665, Length=163, Percent_Identity=29.4478527607362, Blast_Score=63, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24646434, Length=262, Percent_Identity=29.7709923664122, Blast_Score=100, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005662
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004044
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF07650 KH_2; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 34724; Mature: 34592

Theoretical pI: Translated: 10.18; Mature: 10.18

Prosite motif: PS50823 KH_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTESKNRLDKQQKTMVVSILGMPNSGKSTLLNRLIGQKISIVTPKVQTTRSAITGIVTYN
CCCCHHHHHHHHHEEEEEEEECCCCCHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHEEC
LTQLIFIDTPGIFQPKKTLEKAMVRCAWTSIVGADIALLIIDITKKLNEQIQIILTRLIS
EEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QKIKFCIILNKIDICVNNLTQLMNDLKQLSINAKIIAISALNGNGVQELLQYISTIAPIR
HHHHEEEEEHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCHHHHHHHHHHHCCCC
PWLYDEDDITTASMKFLAQEITREQLFLALHQELPYNITVEHERWEQLNDGSVKIYQAIV
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHCCCCCCCEEHHHHH
ANKDNYKAIILGKAGSRIKSIGQKARFAMQKILNLKVCLILFVKIRPTWDQEYSFYEKMG
CCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHEEEHEEEEECCCCCHHHHHHHHHH
LKLIKS
HHHHCC
>Mature Secondary Structure 
TESKNRLDKQQKTMVVSILGMPNSGKSTLLNRLIGQKISIVTPKVQTTRSAITGIVTYN
CCCHHHHHHHHHEEEEEEEECCCCCHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHEEC
LTQLIFIDTPGIFQPKKTLEKAMVRCAWTSIVGADIALLIIDITKKLNEQIQIILTRLIS
EEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QKIKFCIILNKIDICVNNLTQLMNDLKQLSINAKIIAISALNGNGVQELLQYISTIAPIR
HHHHEEEEEHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCHHHHHHHHHHHCCCC
PWLYDEDDITTASMKFLAQEITREQLFLALHQELPYNITVEHERWEQLNDGSVKIYQAIV
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHCCCCCCCEEHHHHH
ANKDNYKAIILGKAGSRIKSIGQKARFAMQKILNLKVCLILFVKIRPTWDQEYSFYEKMG
CCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHEEEHEEEEECCCCCHHHHHHHHHH
LKLIKS
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA