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The map label for this gene is 189026241

Identifier: 189026241

GI number: 189026241

Start: 1111371

End: 1112885

Strand: Direct

Name: 189026241

Synonym: TPASS_1018

Alternate gene names: NA

Gene position: 1111371-1112885 (Clockwise)

Preceding gene: 189026236

Following gene: 189026242

Centisome position: 97.54

GC content: 53.0

Gene sequence:

>1515_bases
ATGACCACGTCTATTGTGATCGGTGTTGTCCTTGTTACTGTCGGTTTAACCTTCGGATGGACCATTCGCTGGCTCTACGC
CAGATTTCACTTATCCGCCTGTGAGCAACGTGCAGAACGTATCCTCCAGGAGGCACAAAAAGAAGCTGAATCCAAAAAGA
AAAGCATTCTCCTTGAAGCAAAAGAATATGTCCTTCGCGAAAGAAATCAGCAGGAACGAGACGACAGAGACCGAAGAGCT
GAGCTGCAGCGTGCAGAGCGACGCCTTCTTCAAAAAGAGGAAGCCCTCTCTACGCGCGCGGGGGAGCTTGATTCTCGAGA
ACGATCGCTAAAACAGCGGGATCAGTCCCTCTGTCAAGAAGAGGCCCGCTATCGCCAGGAGCTCGAGCGTGTCTCTGGCC
TCACTCAGAATCAGGCACGGGATCTCATCATCAAAAACCTTGAGAACGAGGCGAAGCACGACGCACAGGCTCTCATCAAC
AAGATAGAGGAGGACGCGGCTTTGAACGCTGAGCGTCGCGCGCGCGACATCCTCGTTACTACCATGCAGCGTATTACTGC
TGATGTCACCGGTGATGTGACCGTCTCTACGGTGAATCTACCCAGTGAAGAAATGAAAGGACGCATCATTGGGCGCGAGG
GACGTAATATCCGCGCGTTAGAGACACTCACTGGTGCTGACGTTGTCGTAGATGACACACCTGAAGCTGTCGTCATTTCC
TGTTTCGACCCGGTACGCAAAGAGATTGCGCGCATCTCTCTTGAGCGTCTTGTACTTGACGGTCGAATCCATCCGGCGCG
CATTGAGGAAATTGTGCAGAAGGTGACGCAGGAAGTTTCTCAAAAAATCTATGAGGAAGGGGAGAAAGTGCTGTTTGACC
TCGGTATTCACGATATGTGTCCCGAGGGGGTACGGGCACTGGGGCGCCTGTATTTCCGTACAAGCTACGGACAGAATGTA
CTCTACCACTCAAAGGAGGTGGCTCTGCTCGCTTCCATGCTCGCCTCGGAAATCGGCGCAGATGTTGCCATTGCCAAAAG
GGGCGCGTTGCTGCACGATATTGGCAAGGGAGTGGAAACTGATTCAGACCGCAACCACGCAGAAATTGGTATGGAGATGG
CTCGCAAAATGAATGAGGACCCGCGAGTGGTAAACGCCGTTGGTTCTCACCACAACGACATAGAGCCGTGTTGTGTTGAG
TCTTGGCTCGTTCAGGTAGCTGATGCTATCTCTGCTGCGCGTCCTGGTGCTCGGCGTGAAATGGTGGATCACTACGTCAA
GCGTCTAGAAAACCTCGAGGCGATTGCTGAGGGGTTCTCGGGTGTAGAGAAAGCCTACGCTATTCAGGCCGGGCGCGAGT
TGCGTGTTTTAGTGAACAACGATAAAATCCCCGACAGGGACGTGAAGGCACTTGGACGTGACATCGCAAAGAAAATAGAG
AGCGACTTGAAGTATCCTGGGCGTATCCGGGTCACTCTTATTCGAGAAACGCGCGTCGTGGAGTATGCCCGCTGA

Upstream 100 bases:

>100_bases
TCTGAGCAACCTTGCGACAAGATCCTTGACAGAATTCGCACACACCTCTAGCCTCTCGCAAGACAGTTTCGCACCCTTAA
AAAATATAAGGAGCACACAC

Downstream 100 bases:

>100_bases
GCCTCAGGGAGAGGGGAGAGAGTGCACGGGCGTCCGTGCAGGTTTGCATCGGCTGCAGTGACTCTCCTACCTCCCTATTC
TAGTCCGGCGATATTGGTCA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 504; Mature: 503

Protein sequence:

>504_residues
MTTSIVIGVVLVTVGLTFGWTIRWLYARFHLSACEQRAERILQEAQKEAESKKKSILLEAKEYVLRERNQQERDDRDRRA
ELQRAERRLLQKEEALSTRAGELDSRERSLKQRDQSLCQEEARYRQELERVSGLTQNQARDLIIKNLENEAKHDAQALIN
KIEEDAALNAERRARDILVTTMQRITADVTGDVTVSTVNLPSEEMKGRIIGREGRNIRALETLTGADVVVDDTPEAVVIS
CFDPVRKEIARISLERLVLDGRIHPARIEEIVQKVTQEVSQKIYEEGEKVLFDLGIHDMCPEGVRALGRLYFRTSYGQNV
LYHSKEVALLASMLASEIGADVAIAKRGALLHDIGKGVETDSDRNHAEIGMEMARKMNEDPRVVNAVGSHHNDIEPCCVE
SWLVQVADAISAARPGARREMVDHYVKRLENLEAIAEGFSGVEKAYAIQAGRELRVLVNNDKIPDRDVKALGRDIAKKIE
SDLKYPGRIRVTLIRETRVVEYAR

Sequences:

>Translated_504_residues
MTTSIVIGVVLVTVGLTFGWTIRWLYARFHLSACEQRAERILQEAQKEAESKKKSILLEAKEYVLRERNQQERDDRDRRA
ELQRAERRLLQKEEALSTRAGELDSRERSLKQRDQSLCQEEARYRQELERVSGLTQNQARDLIIKNLENEAKHDAQALIN
KIEEDAALNAERRARDILVTTMQRITADVTGDVTVSTVNLPSEEMKGRIIGREGRNIRALETLTGADVVVDDTPEAVVIS
CFDPVRKEIARISLERLVLDGRIHPARIEEIVQKVTQEVSQKIYEEGEKVLFDLGIHDMCPEGVRALGRLYFRTSYGQNV
LYHSKEVALLASMLASEIGADVAIAKRGALLHDIGKGVETDSDRNHAEIGMEMARKMNEDPRVVNAVGSHHNDIEPCCVE
SWLVQVADAISAARPGARREMVDHYVKRLENLEAIAEGFSGVEKAYAIQAGRELRVLVNNDKIPDRDVKALGRDIAKKIE
SDLKYPGRIRVTLIRETRVVEYAR
>Mature_503_residues
TTSIVIGVVLVTVGLTFGWTIRWLYARFHLSACEQRAERILQEAQKEAESKKKSILLEAKEYVLRERNQQERDDRDRRAE
LQRAERRLLQKEEALSTRAGELDSRERSLKQRDQSLCQEEARYRQELERVSGLTQNQARDLIIKNLENEAKHDAQALINK
IEEDAALNAERRARDILVTTMQRITADVTGDVTVSTVNLPSEEMKGRIIGREGRNIRALETLTGADVVVDDTPEAVVISC
FDPVRKEIARISLERLVLDGRIHPARIEEIVQKVTQEVSQKIYEEGEKVLFDLGIHDMCPEGVRALGRLYFRTSYGQNVL
YHSKEVALLASMLASEIGADVAIAKRGALLHDIGKGVETDSDRNHAEIGMEMARKMNEDPRVVNAVGSHHNDIEPCCVES
WLVQVADAISAARPGARREMVDHYVKRLENLEAIAEGFSGVEKAYAIQAGRELRVLVNNDKIPDRDVKALGRDIAKKIES
DLKYPGRIRVTLIRETRVVEYAR

Specific function: Catalyzes the hydrolysis of both 2',3'-cyclic AMP and 2',3'-cyclic GMP into 3'-AMP and 3'-GMP, respectively, at the 3'- terminal of RNA

COG id: COG1418

COG function: function code R; Predicted HD superfamily hydrolase

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CNPD_TREPA (O83981)

Other databases:

- EMBL:   AE000520
- PIR:   F71253
- RefSeq:   NP_219455.1
- ProteinModelPortal:   O83981
- SMR:   O83981
- IntAct:   O83981
- GeneID:   2610865
- GenomeReviews:   AE000520_GR
- KEGG:   tpa:TP1018
- NMPDR:   fig|243276.1.peg.1013
- TIGR:   TP_1018
- HOGENOM:   HBG734610
- OMA:   HPGRIEE
- ProtClustDB:   PRK12705
- BioCyc:   TPAL243276:TP_1018-MONOMER
- HAMAP:   MF_00335
- InterPro:   IPR017705
- InterPro:   IPR022711
- InterPro:   IPR004087
- InterPro:   IPR004088
- InterPro:   IPR018111
- InterPro:   IPR003607
- InterPro:   IPR006675
- SMART:   SM00471
- SMART:   SM00322
- TIGRFAMs:   TIGR00277
- TIGRFAMs:   TIGR03319

Pfam domain/function: PF12072 DUF3552; PF00013 KH_1

EC number: =3.1.4.16

Molecular weight: Translated: 57072; Mature: 56941

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: PS50084 KH_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x21ff9d00)-;

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTSIVIGVVLVTVGLTFGWTIRWLYARFHLSACEQRAERILQEAQKEAESKKKSILLEA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KEYVLRERNQQERDDRDRRAELQRAERRLLQKEEALSTRAGELDSRERSLKQRDQSLCQE
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
EARYRQELERVSGLTQNQARDLIIKNLENEAKHDAQALINKIEEDAALNAERRARDILVT
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
TMQRITADVTGDVTVSTVNLPSEEMKGRIIGREGRNIRALETLTGADVVVDDTPEAVVIS
HHHHHHHCCCCCEEEEEECCCHHHHCCCEECCCCCCEEHHHHHCCCCEEECCCCCEEEEE
CFDPVRKEIARISLERLVLDGRIHPARIEEIVQKVTQEVSQKIYEEGEKVLFDLGIHDMC
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHEEEECCCHHCC
PEGVRALGRLYFRTSYGQNVLYHSKEVALLASMLASEIGADVAIAKRGALLHDIGKGVET
HHHHHHHHHHHHHHCCCCCHHHCHHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHCCCCCC
DSDRNHAEIGMEMARKMNEDPRVVNAVGSHHNDIEPCCVESWLVQVADAISAARPGARRE
CCCCCHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHH
MVDHYVKRLENLEAIAEGFSGVEKAYAIQAGRELRVLVNNDKIPDRDVKALGRDIAKKIE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHH
SDLKYPGRIRVTLIRETRVVEYAR
HHCCCCCEEEEEEEEHHHHHHCCH
>Mature Secondary Structure 
TTSIVIGVVLVTVGLTFGWTIRWLYARFHLSACEQRAERILQEAQKEAESKKKSILLEA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KEYVLRERNQQERDDRDRRAELQRAERRLLQKEEALSTRAGELDSRERSLKQRDQSLCQE
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
EARYRQELERVSGLTQNQARDLIIKNLENEAKHDAQALINKIEEDAALNAERRARDILVT
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
TMQRITADVTGDVTVSTVNLPSEEMKGRIIGREGRNIRALETLTGADVVVDDTPEAVVIS
HHHHHHHCCCCCEEEEEECCCHHHHCCCEECCCCCCEEHHHHHCCCCEEECCCCCEEEEE
CFDPVRKEIARISLERLVLDGRIHPARIEEIVQKVTQEVSQKIYEEGEKVLFDLGIHDMC
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHEEEECCCHHCC
PEGVRALGRLYFRTSYGQNVLYHSKEVALLASMLASEIGADVAIAKRGALLHDIGKGVET
HHHHHHHHHHHHHHCCCCCHHHCHHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHCCCCCC
DSDRNHAEIGMEMARKMNEDPRVVNAVGSHHNDIEPCCVESWLVQVADAISAARPGARRE
CCCCCHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHH
MVDHYVKRLENLEAIAEGFSGVEKAYAIQAGRELRVLVNNDKIPDRDVKALGRDIAKKIE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHH
SDLKYPGRIRVTLIRETRVVEYAR
HHCCCCCEEEEEEEEHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9665876