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The map label for this gene is ftsK

Identifier: 189026222

GI number: 189026222

Start: 1087492

End: 1089891

Strand: Direct

Name: ftsK

Synonym: TPASS_0999

Alternate gene names: 189026222

Gene position: 1087492-1089891 (Clockwise)

Preceding gene: 189026218

Following gene: 189026223

Centisome position: 95.44

GC content: 52.79

Gene sequence:

>2400_bases
ATGGAACGATCCCCTTTACCTAGAATTATCGCTCTTACCTTCGGCACACTGCTATTCGTCAGTGCAGTGCTCCTGACCCT
GTCCACGTTTCTTCCCCTTTTTACCTTGCACCGAGCATCACACTGGTTCTTCGTACCTGGCACTCTCCTTTACGAAACGT
ACGCTTTCTCCTCCTTGCTCGTGCCGCTGTTACTCTTGCACACAGCGCTCCTCTTGTTTGTCGGCGGACGTTCGTTACGG
GCAGAAAGCGCACTTGTTGCCTTCCCACTCTTGTTCATTACTGCAGTGTGTGGAGAACACGGTCTCTACGCGCTACGACG
CGCACTCGCTGCACGGTCAATTTCACCGTCAACGCGGGGAGGGATAGACATCGTATGCGTCCTTTGCCTCCTCGCATTGC
TGGGAGCAGAGCTCTATGCTGCACTCATTTACGGGGAAAGGTGTTACGTATGGTTTCATGCACGTATCCCTCGCGATTTC
ATCGCTGATGGATTCCAAGACCCCTCCTTCCCTCCCTCCACCGCCGATCATCCTGACACCGTTTCCCCTCCCCCCGCTCC
CTCCTGCGCCACCGCAGATGTGCAGACGCCCGAAGCAAGCGCGCCCCCAGAGGGGCAATTCTCCACGGAAGTTCCCCTCC
AGGGGGGAGAATTTTTGATTTCTGAGGCAGAGGTGCAGCCTGCCACGCAGGTGGCAGCGTGTGGCGGTGTGTCCACGCCA
ACTGCTTTGGCGCCATCGGTGCCTTCTCAGGCTCCATTCCCCCTGCTCCCAGCGCCCGGGCTCATTCAGAGTAACCTTCC
CTCAGACGTTCACGCCCCCGCGTCACCCGGGTCTTTGCCGTCTGTCATCCCTGCACAGGCACCGTGTGTCATGGCCCTCT
CTCCTATCTCTGCTCCCTCAGTCGCCCCCGCTGAAACCCTTATTCCTGCGCAAGACGATGAACAGGGACCACCGCGTCCT
ATTCCTGCCTCAGCAGCTCCGCTTCGGCACCCTTGCCGCGGCTACCAAGTACCGTACGACTTGCTTGACCAGTACTCAGA
GGACACATATGAAGGAATTGACGAGCTCACCAAGAATCTTGCACTCCTGCTTGAGGAAACATTCTCTGAATTCAACATTC
GAGTAGAAATCACCGGTATCAAGAAGGGTCCTGTAGTCACAATGTTCGAGCTTCTCCCTCCACCCGGCATCAAACTGTCA
AAAATTACAAATCTGCAGGACAACGTTGCGCTCAAGCTTGCTGCTTCAAGCGTGCGCATCGTCGCTCCCATTCCTGGAAA
ACACGCCATAGGCGTGGAAGTCCCTAACAAAAAACGATCCCTCGTTACATTCAAAGAACTGCTCCATACGCGCACAGCTG
GCAGCAACCGTATGGCCATCCCTGTCATCCTTGGCAAAGACGTTACCGGCGAACCACAGGTTATCGACCTTGCCCAAACA
CCTCACCTGCTCATTGCAGGCGCAACTGGGTCGGGTAAATCAGTATGCGTAAACGCGCTCATTCTCTCTATCCTGTACCA
CAAGTGTCCTGACGAAACCAAACTTCTGCTCATTGATCCAAAAATCGTAGAGTTAAAGCTCTACAACGATATCGCCCACC
TTCTCACTCCTGTCATCACTGAGCCCAAAAGAGCACTCCAAGCACTACAGTACATCCTGTGCGAAATGGAGCGACGCTAT
GCGCTTCTTGAGCAATTAGAATGCCGCGACATTAAGACCTACAACAAAAAAATACAGGAAAAAAGCATCGCCACGCAGCC
TCTCCCATTCATCGTTATTATCATTGATGAATTTGCAGACTTAATGGTTGCCTCTGGCAAAGAATTAGAAACGAGTGTTG
CGCGTTTGTGCGCGATGAGCCGTGCAGTAGGCATCCATTTGGTACTTGCCACCCAGCGACCGTCAATCGATGTCATCACC
GGCCTTATTAAGGCAAATATTCCAAGCAGAATTGCCTTTATGGTTTCATCTAAAATGGATAGCCGTATTATTTTGGATGA
GATGGGCGCAGAAAAATTGCTGGGACGAGGGGATATGCTGTACATGAACCCGAGTCAGTCTTTTCCTACGCGGATTCAAG
GTGCGTATGTTTCCGAGCGAGAATTAGCGCGCGTGATCGCCCATGTACGCGCGTGGGGAACGCCTGAGTATCTTGATGAA
GAAATTTTCTTTGACGATGACGACGCGAGTATATCTGGAAATTTTGTGGATGAAAGCGATCCTTTATACGAGCAGGCAGT
GCAGGTAGTGCAATACGCGGGTAAAGCGTCCACATCGTATGTGCAACGTAAATTGAAGATAGGCTACAATCGCGCCGCGC
GCCTAATCGAAGAAATGGAAGCAAGGGGGGTGGTCGGTCCGCCGAATGGATCCAAGCCACGTGATGTTTTGCGTTCGTAG

Upstream 100 bases:

>100_bases
ATTGGGTCGCGCCTGTTTCCTCCCCTCACTCGGCTCCTTCTGTCGGGGTCGGTAGCCTGCAGGGCGTGCAAGCTAACAGA
TTAACTGTTCAGGACAATGC

Downstream 100 bases:

>100_bases
TTGTTGCACATCTGCGTGTAAGAAAACGACGAACGATTGTTCAACGGACTTTTTGAAACTGCGCAATTGGGGTATGTGTC
CACGGGTAAAAAAGGTGAGG

Product: cell division protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 799; Mature: 799

Protein sequence:

>799_residues
MERSPLPRIIALTFGTLLFVSAVLLTLSTFLPLFTLHRASHWFFVPGTLLYETYAFSSLLVPLLLLHTALLLFVGGRSLR
AESALVAFPLLFITAVCGEHGLYALRRALAARSISPSTRGGIDIVCVLCLLALLGAELYAALIYGERCYVWFHARIPRDF
IADGFQDPSFPPSTADHPDTVSPPPAPSCATADVQTPEASAPPEGQFSTEVPLQGGEFLISEAEVQPATQVAACGGVSTP
TALAPSVPSQAPFPLLPAPGLIQSNLPSDVHAPASPGSLPSVIPAQAPCVMALSPISAPSVAPAETLIPAQDDEQGPPRP
IPASAAPLRHPCRGYQVPYDLLDQYSEDTYEGIDELTKNLALLLEETFSEFNIRVEITGIKKGPVVTMFELLPPPGIKLS
KITNLQDNVALKLAASSVRIVAPIPGKHAIGVEVPNKKRSLVTFKELLHTRTAGSNRMAIPVILGKDVTGEPQVIDLAQT
PHLLIAGATGSGKSVCVNALILSILYHKCPDETKLLLIDPKIVELKLYNDIAHLLTPVITEPKRALQALQYILCEMERRY
ALLEQLECRDIKTYNKKIQEKSIATQPLPFIVIIIDEFADLMVASGKELETSVARLCAMSRAVGIHLVLATQRPSIDVIT
GLIKANIPSRIAFMVSSKMDSRIILDEMGAEKLLGRGDMLYMNPSQSFPTRIQGAYVSERELARVIAHVRAWGTPEYLDE
EIFFDDDDASISGNFVDESDPLYEQAVQVVQYAGKASTSYVQRKLKIGYNRAARLIEEMEARGVVGPPNGSKPRDVLRS

Sequences:

>Translated_799_residues
MERSPLPRIIALTFGTLLFVSAVLLTLSTFLPLFTLHRASHWFFVPGTLLYETYAFSSLLVPLLLLHTALLLFVGGRSLR
AESALVAFPLLFITAVCGEHGLYALRRALAARSISPSTRGGIDIVCVLCLLALLGAELYAALIYGERCYVWFHARIPRDF
IADGFQDPSFPPSTADHPDTVSPPPAPSCATADVQTPEASAPPEGQFSTEVPLQGGEFLISEAEVQPATQVAACGGVSTP
TALAPSVPSQAPFPLLPAPGLIQSNLPSDVHAPASPGSLPSVIPAQAPCVMALSPISAPSVAPAETLIPAQDDEQGPPRP
IPASAAPLRHPCRGYQVPYDLLDQYSEDTYEGIDELTKNLALLLEETFSEFNIRVEITGIKKGPVVTMFELLPPPGIKLS
KITNLQDNVALKLAASSVRIVAPIPGKHAIGVEVPNKKRSLVTFKELLHTRTAGSNRMAIPVILGKDVTGEPQVIDLAQT
PHLLIAGATGSGKSVCVNALILSILYHKCPDETKLLLIDPKIVELKLYNDIAHLLTPVITEPKRALQALQYILCEMERRY
ALLEQLECRDIKTYNKKIQEKSIATQPLPFIVIIIDEFADLMVASGKELETSVARLCAMSRAVGIHLVLATQRPSIDVIT
GLIKANIPSRIAFMVSSKMDSRIILDEMGAEKLLGRGDMLYMNPSQSFPTRIQGAYVSERELARVIAHVRAWGTPEYLDE
EIFFDDDDASISGNFVDESDPLYEQAVQVVQYAGKASTSYVQRKLKIGYNRAARLIEEMEARGVVGPPNGSKPRDVLRS
>Mature_799_residues
MERSPLPRIIALTFGTLLFVSAVLLTLSTFLPLFTLHRASHWFFVPGTLLYETYAFSSLLVPLLLLHTALLLFVGGRSLR
AESALVAFPLLFITAVCGEHGLYALRRALAARSISPSTRGGIDIVCVLCLLALLGAELYAALIYGERCYVWFHARIPRDF
IADGFQDPSFPPSTADHPDTVSPPPAPSCATADVQTPEASAPPEGQFSTEVPLQGGEFLISEAEVQPATQVAACGGVSTP
TALAPSVPSQAPFPLLPAPGLIQSNLPSDVHAPASPGSLPSVIPAQAPCVMALSPISAPSVAPAETLIPAQDDEQGPPRP
IPASAAPLRHPCRGYQVPYDLLDQYSEDTYEGIDELTKNLALLLEETFSEFNIRVEITGIKKGPVVTMFELLPPPGIKLS
KITNLQDNVALKLAASSVRIVAPIPGKHAIGVEVPNKKRSLVTFKELLHTRTAGSNRMAIPVILGKDVTGEPQVIDLAQT
PHLLIAGATGSGKSVCVNALILSILYHKCPDETKLLLIDPKIVELKLYNDIAHLLTPVITEPKRALQALQYILCEMERRY
ALLEQLECRDIKTYNKKIQEKSIATQPLPFIVIIIDEFADLMVASGKELETSVARLCAMSRAVGIHLVLATQRPSIDVIT
GLIKANIPSRIAFMVSSKMDSRIILDEMGAEKLLGRGDMLYMNPSQSFPTRIQGAYVSERELARVIAHVRAWGTPEYLDE
EIFFDDDDASISGNFVDESDPLYEQAVQVVQYAGKASTSYVQRKLKIGYNRAARLIEEMEARGVVGPPNGSKPRDVLRS

Specific function: DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind

COG id: COG1674

COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side. Note=Located at the septum. The large C-terminal part of the protein is cytoplasmic (Potential)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FtsK domain

Homologues:

Organism=Escherichia coli, GI1787117, Length=463, Percent_Identity=48.1641468682505, Blast_Score=434, Evalue=1e-122,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FTSK_TREPA (O83964)

Other databases:

- EMBL:   AE000520
- PIR:   H71255
- RefSeq:   NP_219436.1
- ProteinModelPortal:   O83964
- GeneID:   2610759
- GenomeReviews:   AE000520_GR
- KEGG:   tpa:TP0999
- NMPDR:   fig|243276.1.peg.994
- TIGR:   TP_0999
- HOGENOM:   HBG662140
- OMA:   FRIMEWR
- ProtClustDB:   CLSK2300348
- BioCyc:   TPAL243276:TP_0999-MONOMER
- InterPro:   IPR003593
- InterPro:   IPR018541
- InterPro:   IPR002543
- SMART:   SM00382
- SMART:   SM00843

Pfam domain/function: PF09397 Ftsk_gamma; PF01580 FtsK_SpoIIIE

EC number: NA

Molecular weight: Translated: 86607; Mature: 86607

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: PS50901 FTSK

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x20ff0d68)-; HASH(0x21b4c8c4)-; HASH(0x21f2d700)-;

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERSPLPRIIALTFGTLLFVSAVLLTLSTFLPLFTLHRASHWFFVPGTLLYETYAFSSLL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHH
VPLLLLHTALLLFVGGRSLRAESALVAFPLLFITAVCGEHGLYALRRALAARSISPSTRG
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCC
GIDIVCVLCLLALLGAELYAALIYGERCYVWFHARIPRDFIADGFQDPSFPPSTADHPDT
CHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCHHHHHCCCCCCCCCCCCCCCCCC
VSPPPAPSCATADVQTPEASAPPEGQFSTEVPLQGGEFLISEAEVQPATQVAACGGVSTP
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCHHHHHHCCCCCCC
TALAPSVPSQAPFPLLPAPGLIQSNLPSDVHAPASPGSLPSVIPAQAPCVMALSPISAPS
CCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCC
VAPAETLIPAQDDEQGPPRPIPASAAPLRHPCRGYQVPYDLLDQYSEDTYEGIDELTKNL
CCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHH
ALLLEETFSEFNIRVEITGIKKGPVVTMFELLPPPGIKLSKITNLQDNVALKLAASSVRI
HHHHHHHHHHCEEEEEEEEECCCCEEEHEECCCCCCCCHHHCCCCCCCEEEEEEECCEEE
VAPIPGKHAIGVEVPNKKRSLVTFKELLHTRTAGSNRMAIPVILGKDVTGEPQVIDLAQT
EEECCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCEEEECCC
PHLLIAGATGSGKSVCVNALILSILYHKCPDETKLLLIDPKIVELKLYNDIAHLLTPVIT
CEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCEEEEEEEHHHHHHHHHHHHC
EPKRALQALQYILCEMERRYALLEQLECRDIKTYNKKIQEKSIATQPLPFIVIIIDEFAD
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHH
LMVASGKELETSVARLCAMSRAVGIHLVLATQRPSIDVITGLIKANIPSRIAFMVSSKMD
HHHHCCCHHHHHHHHHHHHHHHCEEEEEEECCCCCHHHHHHHHHCCCCHHHHHHHHCCCC
SRIILDEMGAEKLLGRGDMLYMNPSQSFPTRIQGAYVSERELARVIAHVRAWGTPEYLDE
CEEHHHHCCHHHHHCCCCEEEECCCCCCCCHHCCCCCCHHHHHHHHHHHHCCCCHHHCCC
EIFFDDDDASISGNFVDESDPLYEQAVQVVQYAGKASTSYVQRKLKIGYNRAARLIEEME
CCEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCHHHHHHHHHHHH
ARGVVGPPNGSKPRDVLRS
HCCCCCCCCCCCHHHHHCH
>Mature Secondary Structure
MERSPLPRIIALTFGTLLFVSAVLLTLSTFLPLFTLHRASHWFFVPGTLLYETYAFSSLL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHH
VPLLLLHTALLLFVGGRSLRAESALVAFPLLFITAVCGEHGLYALRRALAARSISPSTRG
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCC
GIDIVCVLCLLALLGAELYAALIYGERCYVWFHARIPRDFIADGFQDPSFPPSTADHPDT
CHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCHHHHHCCCCCCCCCCCCCCCCCC
VSPPPAPSCATADVQTPEASAPPEGQFSTEVPLQGGEFLISEAEVQPATQVAACGGVSTP
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCHHHHHHCCCCCCC
TALAPSVPSQAPFPLLPAPGLIQSNLPSDVHAPASPGSLPSVIPAQAPCVMALSPISAPS
CCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCC
VAPAETLIPAQDDEQGPPRPIPASAAPLRHPCRGYQVPYDLLDQYSEDTYEGIDELTKNL
CCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHH
ALLLEETFSEFNIRVEITGIKKGPVVTMFELLPPPGIKLSKITNLQDNVALKLAASSVRI
HHHHHHHHHHCEEEEEEEEECCCCEEEHEECCCCCCCCHHHCCCCCCCEEEEEEECCEEE
VAPIPGKHAIGVEVPNKKRSLVTFKELLHTRTAGSNRMAIPVILGKDVTGEPQVIDLAQT
EEECCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCEEEECCC
PHLLIAGATGSGKSVCVNALILSILYHKCPDETKLLLIDPKIVELKLYNDIAHLLTPVIT
CEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCEEEEEEEHHHHHHHHHHHHC
EPKRALQALQYILCEMERRYALLEQLECRDIKTYNKKIQEKSIATQPLPFIVIIIDEFAD
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHH
LMVASGKELETSVARLCAMSRAVGIHLVLATQRPSIDVITGLIKANIPSRIAFMVSSKMD
HHHHCCCHHHHHHHHHHHHHHHCEEEEEEECCCCCHHHHHHHHHCCCCHHHHHHHHCCCC
SRIILDEMGAEKLLGRGDMLYMNPSQSFPTRIQGAYVSERELARVIAHVRAWGTPEYLDE
CEEHHHHCCHHHHHCCCCEEEECCCCCCCCHHCCCCCCHHHHHHHHHHHHCCCCHHHCCC
EIFFDDDDASISGNFVDESDPLYEQAVQVVQYAGKASTSYVQRKLKIGYNRAARLIEEME
CCEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCHHHHHHHHHHHH
ARGVVGPPNGSKPRDVLRS
HCCCCCCCCCCCHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9665876