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The map label for this gene is lspA [H]

Identifier: 189026201

GI number: 189026201

Start: 1062923

End: 1063516

Strand: Direct

Name: lspA [H]

Synonym: TPASS_0978

Alternate gene names: 189026201

Gene position: 1062923-1063516 (Clockwise)

Preceding gene: 189026200

Following gene: 189026202

Centisome position: 93.28

GC content: 50.17

Gene sequence:

>594_bases
GTGATACGCTCGCGCCCGTTAAGGGTGGATACAATGAAACTCACACGGATACAGAAAGAAAAGTGGATCCCGCTTTTTGC
CGCTGGATTAGTTGTTGTTCTGGATCAGTGCGCTAAATTGTTGGTGGGTGCTTATGTGCCTACAAACACCTCGGGCGTTC
GCGTGCTCGGTGATTTCGTGAGAATTGTTCACGTGTACAATGTTGGCGCCGCTTTCAGCATTGGCCATCAGCTAAATCAG
GTTCTGCGTACGCTCGTGCTCGGTATCGTGCCGCTAATCATTATGTTCCTTATTGTTTTCTCCTATTTTCGCACTGACGC
CTTCTGTCCTGTTCAGCGCTGGGCCGTGTCAGGGATTATCGGGGGAGGGATAGGGAACTTAATCGATCGCTTCCTGAGGC
CAAACGGGGTGCTCGACTTTATCGACGTAAAGTTCTTTGGCATCTTTGGCTTTGAGCGCTGGCCCGCTTTTAACATTGCA
GATGCGGTCATCATGACCTGTGGTTTGCTCTTGATCATTTCGTTCATAAAACAAGAAAAAGAGATCAGCTCCCAACCCTC
CTGCAATGAGACGGGGGGCGTTTTGCGCACGTAG

Upstream 100 bases:

>100_bases
GACACTACCAAACAGAAACCGTAGGGTTGCAGCTGGTGGCGCGCAAGCTGCAACGGGATACAGGCATAGAAACGCTTTTT
CTAGACATTCCCACGGGGAT

Downstream 100 bases:

>100_bases
AGCTGGGCCGTGCGCGCATGTCCGCGTCGGCCGTTCTAGTTCGCGTGCCCCTGTGCCCGCAATGGTTGCTTTGTTCTCCG
CAAATACCGCGCGTGTGTGC

Product: signal peptidase II

Products: NA

Alternate protein names: Prolipoprotein signal peptidase; Signal peptidase II; SPase II [H]

Number of amino acids: Translated: 197; Mature: 197

Protein sequence:

>197_residues
MIRSRPLRVDTMKLTRIQKEKWIPLFAAGLVVVLDQCAKLLVGAYVPTNTSGVRVLGDFVRIVHVYNVGAAFSIGHQLNQ
VLRTLVLGIVPLIIMFLIVFSYFRTDAFCPVQRWAVSGIIGGGIGNLIDRFLRPNGVLDFIDVKFFGIFGFERWPAFNIA
DAVIMTCGLLLIISFIKQEKEISSQPSCNETGGVLRT

Sequences:

>Translated_197_residues
MIRSRPLRVDTMKLTRIQKEKWIPLFAAGLVVVLDQCAKLLVGAYVPTNTSGVRVLGDFVRIVHVYNVGAAFSIGHQLNQ
VLRTLVLGIVPLIIMFLIVFSYFRTDAFCPVQRWAVSGIIGGGIGNLIDRFLRPNGVLDFIDVKFFGIFGFERWPAFNIA
DAVIMTCGLLLIISFIKQEKEISSQPSCNETGGVLRT
>Mature_197_residues
MIRSRPLRVDTMKLTRIQKEKWIPLFAAGLVVVLDQCAKLLVGAYVPTNTSGVRVLGDFVRIVHVYNVGAAFSIGHQLNQ
VLRTLVLGIVPLIIMFLIVFSYFRTDAFCPVQRWAVSGIIGGGIGNLIDRFLRPNGVLDFIDVKFFGIFGFERWPAFNIA
DAVIMTCGLLLIISFIKQEKEISSQPSCNETGGVLRT

Specific function: This protein specifically catalyzes the removal of signal peptides from prolipoproteins [H]

COG id: COG0597

COG function: function code MU; Lipoprotein signal peptidase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A8 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001872 [H]

Pfam domain/function: PF01252 Peptidase_A8 [H]

EC number: =3.4.23.36 [H]

Molecular weight: Translated: 21888; Mature: 21888

Theoretical pI: Translated: 9.96; Mature: 9.96

Prosite motif: PS00855 SPASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRSRPLRVDTMKLTRIQKEKWIPLFAAGLVVVLDQCAKLLVGAYVPTNTSGVRVLGDFV
CCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
RIVHVYNVGAAFSIGHQLNQVLRTLVLGIVPLIIMFLIVFSYFRTDAFCPVQRWAVSGII
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
GGGIGNLIDRFLRPNGVLDFIDVKFFGIFGFERWPAFNIADAVIMTCGLLLIISFIKQEK
CCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
EISSQPSCNETGGVLRT
HHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MIRSRPLRVDTMKLTRIQKEKWIPLFAAGLVVVLDQCAKLLVGAYVPTNTSGVRVLGDFV
CCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
RIVHVYNVGAAFSIGHQLNQVLRTLVLGIVPLIIMFLIVFSYFRTDAFCPVQRWAVSGII
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
GGGIGNLIDRFLRPNGVLDFIDVKFFGIFGFERWPAFNIADAVIMTCGLLLIISFIKQEK
CCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
EISSQPSCNETGGVLRT
HHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9665876 [H]