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The map label for this gene is pbp3 [H]

Identifier: 189025985

GI number: 189025985

Start: 823674

End: 825632

Strand: Direct

Name: pbp3 [H]

Synonym: TPASS_0760

Alternate gene names: 189025985

Gene position: 823674-825632 (Clockwise)

Preceding gene: 189025984

Following gene: 189025986

Centisome position: 72.29

GC content: 54.26

Gene sequence:

>1959_bases
TTGTCCGCACCGACCTCCTTTCGAGTGCATCCGTGGGACGCTAGCCTACCCTGCACAGGCGTCCACCCCTCCTGGGAAGA
GGCCCGACCTGCCGTGAACATTACCCGAAGCCGCGTTGCGGTCTTTATCTCCTCCCTGACCGCTGTGCTTCTGCTGCTCA
CCGTTCAGTGCGCGCGGTATATGCTCATGCGTGGCAACGAGACAAAGGAACTGAACACACTCACTGAACGCGGCGCGATC
TTGGACCGAAATGGCCGGTTTCTTGCCGTTGGAACCACCGTCTACAACCTCAGTGTTAACAAAAATCTTGTCTCAGACCC
ACGCACTGCAGCCCACGTGTTAGCACAGGTCCTTGACCTTTCAGAACAAGATATTGAAGAAAAATTCCGCACCGCGCGCG
CTCACTTCTTTTACCTCAAGAAAAAAATGAGTGAAACGGAAAAGAACCTTGTCGCTCACGCTCTTAAGGAGCACTCCCTG
AAAGGATTTCGCCTAGAGGCAGTGCGCAACCGCATCTATCCAGAAAGTAGCCTAGCGTCCACGGTCATCGGATACGTAGG
TGATGACGGAAGGGGACTGAGCGGTATCGAGTACACCTTGCAGGATGTTCTTTCTCCTGCCCCGTACCACACCGGGTATA
CGGGCAAGGGGCATACTGTCACCCTCTCGATCGACCGAACCATCCAGTACATGATGGAAAAAATCGCAGATACTACGCTC
CGGCGTACCCAGGCAGAAGGACTCATGTTCCTTGCGGTGGAGGCAAAGACAGGTCAGATTCTATCCTACGTCAGCAAGCC
GTCTGCTAACCTTTCACACTTTTCCCAAAGTACCCCTGCCGAACGCTTCGATCGCCCCGCCCTTTTCATCTATGAGCCTG
GCTCTGTGTTCAAAATTTTTTCCATCGCTGCACTGTTAGAACTCGGGGTAACTTACACCCACGACACGCTCCACTGCGAC
GGTTCCTTCTCCTTTACCTCCCCCTTTTTAAAACCAGGTCAAAAAGGCCATCTCATCCGCTGCCTGCGCCCACACGGCAC
CATCAGCGCTGAAGATATCATCCGGCTTTCGTGTAATGACGGCATGGCACAAATTGCTGAACGTGCCGACAACCACAGCT
TTGAGCAACTATTGCGCGCTTTTGGATTTGGCGCGAAAACAGAAATTGAGTTGCCGGGGGAAACCGTCGGTCTCTTCTCT
CCCTCAGAACGCTGGTCCCACCGCAGCAAGCACACCATCGCAATCGGCCAGGAAATTGGCGTCTCTGCCTTGCAGGTTGT
GGCTGCCGCTACCGCGCTCGCCAACGAGGGCGTACCGCTCGGCCTCTCCCTCCTCCATGAGGTCACTACCGCCGAAGGTA
CCGTGGTGTACCGGCACAAAAAGAAACCCAAAACACGCGTTATCTCCGCAGTAAATGCGCAAAAGGTGTTGCGATACATG
CGCACCGCCGCAGAACTTGGCACCGGGAAAAAGGCGCTCGTAGACGGGGTGCCGATCGCAGTCAAAACAGGCACTGCGCA
AATGGCGCACAGAAATGGTCGTGGGTACAGCGACACCGACTACCTTGCAAGTTGCATCGGCCTTTTCCCCGCGCACGATC
CAGAAATTATCTTATACATTGCCATCATCCGTCCTATCGGACAAGCCTATGGAGAGCTCATTGCAGCGCCTGTCATCTCT
CAAGCGGCAAACGAGATTATCGACTACCGCGGTATGGTCCGTGCCAACGCCCCGTTAATCCAACATAGCGGTCTCATCCA
TACGTCAGAACGGACACCTCCACGGTTAGGAACCCATATGCCAGACCTCACCGGTCAACCTAAACGTTTACTCCTGGATA
TTGCAAAACGCACCGACGTGCACCTTGTCCTTACAGGAGAAGGTTATGTGTACGAGCAGCATCCGCCTGCGGGCACACCT
CTGACAAAAGGAATGACCATTGAACTCAAACTCAAATAA

Upstream 100 bases:

>100_bases
CCCTGCACGCACACCCTACGTGTCTTGCTTATGCAACCGCTGACCTTCCTAACGTGCGTCTACTTGTGGTACAGTGCAGC
GCTGTGCGTAGAAGTCAAAA

Downstream 100 bases:

>100_bases
AAAGCGAGATCCCGCGCGTTTCCCGGCCGGTGTTGCGCAAGGCTGCAGTACCACACGCGCAGGGGATCTGAAACACAGAA
GAAAGCATCCCTTTGAGAAG

Product: penicillin-binding protein

Products: NA

Alternate protein names: Sporulation-specific penicillin-binding protein [H]

Number of amino acids: Translated: 652; Mature: 651

Protein sequence:

>652_residues
MSAPTSFRVHPWDASLPCTGVHPSWEEARPAVNITRSRVAVFISSLTAVLLLLTVQCARYMLMRGNETKELNTLTERGAI
LDRNGRFLAVGTTVYNLSVNKNLVSDPRTAAHVLAQVLDLSEQDIEEKFRTARAHFFYLKKKMSETEKNLVAHALKEHSL
KGFRLEAVRNRIYPESSLASTVIGYVGDDGRGLSGIEYTLQDVLSPAPYHTGYTGKGHTVTLSIDRTIQYMMEKIADTTL
RRTQAEGLMFLAVEAKTGQILSYVSKPSANLSHFSQSTPAERFDRPALFIYEPGSVFKIFSIAALLELGVTYTHDTLHCD
GSFSFTSPFLKPGQKGHLIRCLRPHGTISAEDIIRLSCNDGMAQIAERADNHSFEQLLRAFGFGAKTEIELPGETVGLFS
PSERWSHRSKHTIAIGQEIGVSALQVVAAATALANEGVPLGLSLLHEVTTAEGTVVYRHKKKPKTRVISAVNAQKVLRYM
RTAAELGTGKKALVDGVPIAVKTGTAQMAHRNGRGYSDTDYLASCIGLFPAHDPEIILYIAIIRPIGQAYGELIAAPVIS
QAANEIIDYRGMVRANAPLIQHSGLIHTSERTPPRLGTHMPDLTGQPKRLLLDIAKRTDVHLVLTGEGYVYEQHPPAGTP
LTKGMTIELKLK

Sequences:

>Translated_652_residues
MSAPTSFRVHPWDASLPCTGVHPSWEEARPAVNITRSRVAVFISSLTAVLLLLTVQCARYMLMRGNETKELNTLTERGAI
LDRNGRFLAVGTTVYNLSVNKNLVSDPRTAAHVLAQVLDLSEQDIEEKFRTARAHFFYLKKKMSETEKNLVAHALKEHSL
KGFRLEAVRNRIYPESSLASTVIGYVGDDGRGLSGIEYTLQDVLSPAPYHTGYTGKGHTVTLSIDRTIQYMMEKIADTTL
RRTQAEGLMFLAVEAKTGQILSYVSKPSANLSHFSQSTPAERFDRPALFIYEPGSVFKIFSIAALLELGVTYTHDTLHCD
GSFSFTSPFLKPGQKGHLIRCLRPHGTISAEDIIRLSCNDGMAQIAERADNHSFEQLLRAFGFGAKTEIELPGETVGLFS
PSERWSHRSKHTIAIGQEIGVSALQVVAAATALANEGVPLGLSLLHEVTTAEGTVVYRHKKKPKTRVISAVNAQKVLRYM
RTAAELGTGKKALVDGVPIAVKTGTAQMAHRNGRGYSDTDYLASCIGLFPAHDPEIILYIAIIRPIGQAYGELIAAPVIS
QAANEIIDYRGMVRANAPLIQHSGLIHTSERTPPRLGTHMPDLTGQPKRLLLDIAKRTDVHLVLTGEGYVYEQHPPAGTP
LTKGMTIELKLK
>Mature_651_residues
SAPTSFRVHPWDASLPCTGVHPSWEEARPAVNITRSRVAVFISSLTAVLLLLTVQCARYMLMRGNETKELNTLTERGAIL
DRNGRFLAVGTTVYNLSVNKNLVSDPRTAAHVLAQVLDLSEQDIEEKFRTARAHFFYLKKKMSETEKNLVAHALKEHSLK
GFRLEAVRNRIYPESSLASTVIGYVGDDGRGLSGIEYTLQDVLSPAPYHTGYTGKGHTVTLSIDRTIQYMMEKIADTTLR
RTQAEGLMFLAVEAKTGQILSYVSKPSANLSHFSQSTPAERFDRPALFIYEPGSVFKIFSIAALLELGVTYTHDTLHCDG
SFSFTSPFLKPGQKGHLIRCLRPHGTISAEDIIRLSCNDGMAQIAERADNHSFEQLLRAFGFGAKTEIELPGETVGLFSP
SERWSHRSKHTIAIGQEIGVSALQVVAAATALANEGVPLGLSLLHEVTTAEGTVVYRHKKKPKTRVISAVNAQKVLRYMR
TAAELGTGKKALVDGVPIAVKTGTAQMAHRNGRGYSDTDYLASCIGLFPAHDPEIILYIAIIRPIGQAYGELIAAPVISQ
AANEIIDYRGMVRANAPLIQHSGLIHTSERTPPRLGTHMPDLTGQPKRLLLDIAKRTDVHLVLTGEGYVYEQHPPAGTPL
TKGMTIELKLK

Specific function: Penicillin-binding protein with an unknown catalytic activity. May have a specialized role in the morphogenesis of spore cortex, which is a modified form of peptidoglycan. Pore cortex formation is determined primarily by the mother cell [H]

COG id: COG0768

COG function: function code M; Cell division protein FtsI/penicillin-binding protein 2

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PASTA domain [H]

Homologues:

Organism=Escherichia coli, GI1786272, Length=527, Percent_Identity=25.426944971537, Blast_Score=144, Evalue=2e-35,
Organism=Escherichia coli, GI1786854, Length=484, Percent_Identity=25.2066115702479, Blast_Score=91, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR005543
- InterPro:   IPR005311
- InterPro:   IPR001460
- InterPro:   IPR011927 [H]

Pfam domain/function: PF03793 PASTA; PF03717 PBP_dimer; PF00905 Transpeptidase [H]

EC number: NA

Molecular weight: Translated: 71519; Mature: 71388

Theoretical pI: Translated: 9.21; Mature: 9.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAPTSFRVHPWDASLPCTGVHPSWEEARPAVNITRSRVAVFISSLTAVLLLLTVQCARY
CCCCCCCEEECCCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MLMRGNETKELNTLTERGAILDRNGRFLAVGTTVYNLSVNKNLVSDPRTAAHVLAQVLDL
HHHCCCCCHHHHHHHHCCCEEECCCCEEEEEEEEEEEEECCCCCCCCHHHHHHHHHHHCC
SEQDIEEKFRTARAHFFYLKKKMSETEKNLVAHALKEHSLKGFRLEAVRNRIYPESSLAS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHCCCCHHHHH
TVIGYVGDDGRGLSGIEYTLQDVLSPAPYHTGYTGKGHTVTLSIDRTIQYMMEKIADTTL
HHHHEECCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHH
RRTQAEGLMFLAVEAKTGQILSYVSKPSANLSHFSQSTPAERFDRPALFIYEPGSVFKIF
HHHHCCCEEEEEEECCCCHHHHHHCCCCCCHHHHCCCCCHHHHCCCEEEEECCCCHHHHH
SIAALLELGVTYTHDTLHCDGSFSFTSPFLKPGQKGHLIRCLRPHGTISAEDIIRLSCND
HHHHHHHHCCEEECCEEEECCCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHEEEEECCC
GMAQIAERADNHSFEQLLRAFGFGAKTEIELPGETVGLFSPSERWSHRSKHTIAIGQEIG
CHHHHHHHCCCCHHHHHHHHHCCCCCEEEECCCCEEECCCCHHHHCCCCCCEEEECCHHC
VSALQVVAAATALANEGVPLGLSLLHEVTTAEGTVVYRHKKKPKTRVISAVNAQKVLRYM
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHH
RTAAELGTGKKALVDGVPIAVKTGTAQMAHRNGRGYSDTDYLASCIGLFPAHDPEIILYI
HHHHHHCCCCHHHHCCCCEEEECCCHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCEEEEH
AIIRPIGQAYGELIAAPVISQAANEIIDYRGMVRANAPLIQHSGLIHTSERTPPRLGTHM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCEEECCCCEECCCCCCCCCCCCC
PDLTGQPKRLLLDIAKRTDVHLVLTGEGYVYEQHPPAGTPLTKGMTIELKLK
CCCCCCCHHHHHHHHCCCCEEEEEECCCEEEECCCCCCCCCCCCEEEEEEEC
>Mature Secondary Structure 
SAPTSFRVHPWDASLPCTGVHPSWEEARPAVNITRSRVAVFISSLTAVLLLLTVQCARY
CCCCCCEEECCCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MLMRGNETKELNTLTERGAILDRNGRFLAVGTTVYNLSVNKNLVSDPRTAAHVLAQVLDL
HHHCCCCCHHHHHHHHCCCEEECCCCEEEEEEEEEEEEECCCCCCCCHHHHHHHHHHHCC
SEQDIEEKFRTARAHFFYLKKKMSETEKNLVAHALKEHSLKGFRLEAVRNRIYPESSLAS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHCCCCHHHHH
TVIGYVGDDGRGLSGIEYTLQDVLSPAPYHTGYTGKGHTVTLSIDRTIQYMMEKIADTTL
HHHHEECCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHH
RRTQAEGLMFLAVEAKTGQILSYVSKPSANLSHFSQSTPAERFDRPALFIYEPGSVFKIF
HHHHCCCEEEEEEECCCCHHHHHHCCCCCCHHHHCCCCCHHHHCCCEEEEECCCCHHHHH
SIAALLELGVTYTHDTLHCDGSFSFTSPFLKPGQKGHLIRCLRPHGTISAEDIIRLSCND
HHHHHHHHCCEEECCEEEECCCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHEEEEECCC
GMAQIAERADNHSFEQLLRAFGFGAKTEIELPGETVGLFSPSERWSHRSKHTIAIGQEIG
CHHHHHHHCCCCHHHHHHHHHCCCCCEEEECCCCEEECCCCHHHHCCCCCCEEEECCHHC
VSALQVVAAATALANEGVPLGLSLLHEVTTAEGTVVYRHKKKPKTRVISAVNAQKVLRYM
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHH
RTAAELGTGKKALVDGVPIAVKTGTAQMAHRNGRGYSDTDYLASCIGLFPAHDPEIILYI
HHHHHHCCCCHHHHCCCCEEEECCCHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCEEEEH
AIIRPIGQAYGELIAAPVISQAANEIIDYRGMVRANAPLIQHSGLIHTSERTPPRLGTHM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCEEECCCCEECCCCCCCCCCCCC
PDLTGQPKRLLLDIAKRTDVHLVLTGEGYVYEQHPPAGTPLTKGMTIELKLK
CCCCCCCHHHHHHHHCCCCEEEEEECCCEEEECCCCCCCCCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8289242; 9384377; 8244929; 8436954 [H]