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The map label for this gene is flhB

Identifier: 189025940

GI number: 189025940

Start: 785093

End: 786223

Strand: Reverse

Name: flhB

Synonym: TPASS_0715

Alternate gene names: 189025940

Gene position: 786223-785093 (Counterclockwise)

Preceding gene: 189025941

Following gene: 189025939

Centisome position: 69.0

GC content: 41.56

Gene sequence:

>1131_bases
ATGATAGAACAAGAAGGAACATTTCCGCTTCCTCTTTTTATTATTGATTTGCAGTGGTTTGCCGCTGAGGATGAAGGGAG
GTCAGAGGATCCTACCGAAACAAAACTCCGTAAAGCACGAGAAGAAGGACGTGTTCCGAAAAGCCAGGATCTAAATGGAG
CGTTTGTGATGCTCTTCACATCAACTTCCTTGTTCTTGCTTGCACCATTTATATTGAGAGAGTGCATCGGTGTACTCAGG
TTTTTCTTTACGCGTGCTACTACCGCGTCCATCCAGAATACTGGATGGTTTTTTGTATTTGTGCGGTATTTTATGAAACT
TGCACTTCCGATATCCTTTGTTGCGCTGGTCTCTGGCGTTGCGGCAAACATTGTACAAAACAAGACCGTTTTATTTTCGG
TAAAGTCGATTCGACCGCAGTTTAAGAAAATATCTCCAGATGTAATTCGTTTTTTCAAACGCTCATTTTTTTCAACAGAA
GGGCTTTTCAATTTACTTAAATCTCTCATAAAGATTACAGCGATATTTTTTGTATCGTATTTTACTATACGTAATGATCT
TTTTATGTTTGTTTCTTTATTGGGTGTGAGTCTTACCCAGAGTATTTTCTACATTACATCCCTTGCGGGTAAAGTTCTCC
TCGAAGTAAGTTTGCTGTTAGTGGTGTTCTCGCTTCCCGATTATTTCTTCCAAAGAAGGCAATTCATCGATTCGTTAAAA
ATGTCTCGGCAGGAAGTGAAAGAGGAGTTAAAAGAGCAGGAAGGGGACCCGCTCGTGAGAAGTTATGTTAGAAAGCAGAT
GCAATCTCTTGTTAGAGAGTCTGCTCGGAATACCACTGACGCTGATGTTGTGATCACTAATCCGACTCATTTTGCAGTTG
CGGTGCAATATGAGCCTGCATACATGACTGCGCCGACTGTGGTTGCGAAAGGATCTGATGGGACTGCATACCGAATCAAA
CGGTTGGCAAAAGAGGCAGGTATCTTGATAGAAGAAAACAAACCGCTTGCACGTGCGTTGTACACGCAGGTTGCTATCGG
GAGAGAAGTTCCCTACGAATATTTTAATGCTTTAGTGCTGATTTTTACCAAGCTGGATAAATTTAAAACACATGCACAGC
GTAAGAGGTAA

Upstream 100 bases:

>100_bases
TGAGCGTAATTCTTCCTTACATGATAAACCTGTTTGTTTCTATACTGTTTGGCGGTTTTGAAATGTTTGAGCAGCTCTTG
GTAAAGCTTGGAAAAGCCCT

Downstream 100 bases:

>100_bases
CCCATACTATGGCGCACGGTAAGAGTGCCTTTTTCACTACTGACGCTTTTGTTGCGATTTCAGTGTTGGTGGTTGTCTTT
TCTATTGTTGTTCCTCTGCC

Product: flagellar biosynthesis protein FlhB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 376; Mature: 376

Protein sequence:

>376_residues
MIEQEGTFPLPLFIIDLQWFAAEDEGRSEDPTETKLRKAREEGRVPKSQDLNGAFVMLFTSTSLFLLAPFILRECIGVLR
FFFTRATTASIQNTGWFFVFVRYFMKLALPISFVALVSGVAANIVQNKTVLFSVKSIRPQFKKISPDVIRFFKRSFFSTE
GLFNLLKSLIKITAIFFVSYFTIRNDLFMFVSLLGVSLTQSIFYITSLAGKVLLEVSLLLVVFSLPDYFFQRRQFIDSLK
MSRQEVKEELKEQEGDPLVRSYVRKQMQSLVRESARNTTDADVVITNPTHFAVAVQYEPAYMTAPTVVAKGSDGTAYRIK
RLAKEAGILIEENKPLARALYTQVAIGREVPYEYFNALVLIFTKLDKFKTHAQRKR

Sequences:

>Translated_376_residues
MIEQEGTFPLPLFIIDLQWFAAEDEGRSEDPTETKLRKAREEGRVPKSQDLNGAFVMLFTSTSLFLLAPFILRECIGVLR
FFFTRATTASIQNTGWFFVFVRYFMKLALPISFVALVSGVAANIVQNKTVLFSVKSIRPQFKKISPDVIRFFKRSFFSTE
GLFNLLKSLIKITAIFFVSYFTIRNDLFMFVSLLGVSLTQSIFYITSLAGKVLLEVSLLLVVFSLPDYFFQRRQFIDSLK
MSRQEVKEELKEQEGDPLVRSYVRKQMQSLVRESARNTTDADVVITNPTHFAVAVQYEPAYMTAPTVVAKGSDGTAYRIK
RLAKEAGILIEENKPLARALYTQVAIGREVPYEYFNALVLIFTKLDKFKTHAQRKR
>Mature_376_residues
MIEQEGTFPLPLFIIDLQWFAAEDEGRSEDPTETKLRKAREEGRVPKSQDLNGAFVMLFTSTSLFLLAPFILRECIGVLR
FFFTRATTASIQNTGWFFVFVRYFMKLALPISFVALVSGVAANIVQNKTVLFSVKSIRPQFKKISPDVIRFFKRSFFSTE
GLFNLLKSLIKITAIFFVSYFTIRNDLFMFVSLLGVSLTQSIFYITSLAGKVLLEVSLLLVVFSLPDYFFQRRQFIDSLK
MSRQEVKEELKEQEGDPLVRSYVRKQMQSLVRESARNTTDADVVITNPTHFAVAVQYEPAYMTAPTVVAKGSDGTAYRIK
RLAKEAGILIEENKPLARALYTQVAIGREVPYEYFNALVLIFTKLDKFKTHAQRKR

Specific function: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with fliI and fliH, may constitute the export apparatus of flagellin

COG id: COG1377

COG function: function code NU; Flagellar biosynthesis pathway, component FlhB

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type III secretion exporter family

Homologues:

Organism=Escherichia coli, GI1788188, Length=354, Percent_Identity=29.6610169491525, Blast_Score=153, Evalue=2e-38,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): FLHB_TREPA (O83710)

Other databases:

- EMBL:   U36839
- EMBL:   AE000520
- PIR:   G71290
- RefSeq:   NP_219152.1
- ProteinModelPortal:   O83710
- SMR:   O83710
- IntAct:   O83710
- MINT:   MINT-6480134
- GeneID:   2610989
- GenomeReviews:   AE000520_GR
- KEGG:   tpa:TP0715
- NMPDR:   fig|243276.1.peg.711
- TIGR:   TP_0715
- HOGENOM:   HBG529770
- OMA:   YVLQLKA
- ProtClustDB:   PRK05702
- BioCyc:   TPAL243276:TP_0715-MONOMER
- InterPro:   IPR006136
- InterPro:   IPR006135
- PRINTS:   PR00950
- TIGRFAMs:   TIGR00328

Pfam domain/function: PF01312 Bac_export_2

EC number: NA

Molecular weight: Translated: 43040; Mature: 43040

Theoretical pI: Translated: 10.20; Mature: 10.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x216dadbc)-; HASH(0x2164f328)-; HASH(0x216919dc)-; HASH(0x206a070c)-;

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEQEGTFPLPLFIIDLQWFAAEDEGRSEDPTETKLRKAREEGRVPKSQDLNGAFVMLFT
CCCCCCCCCCEEEEEEHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEEEC
STSLFLLAPFILRECIGVLRFFFTRATTASIQNTGWFFVFVRYFMKLALPISFVALVSGV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AANIVQNKTVLFSVKSIRPQFKKISPDVIRFFKRSFFSTEGLFNLLKSLIKITAIFFVSY
HHHHHCCCHHEEEEHHHCHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
FTIRNDLFMFVSLLGVSLTQSIFYITSLAGKVLLEVSLLLVVFSLPDYFFQRRQFIDSLK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MSRQEVKEELKEQEGDPLVRSYVRKQMQSLVRESARNTTDADVVITNPTHFAVAVQYEPA
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCEEEEEEEECCC
YMTAPTVVAKGSDGTAYRIKRLAKEAGILIEENKPLARALYTQVAIGREVPYEYFNALVL
EEECCCEEEECCCCHHHHHHHHHHHCCEEEECCCHHHHHHHHHHHHCCCCCHHHHHHHHH
IFTKLDKFKTHAQRKR
HHHHHHHHHHHHHCCH
>Mature Secondary Structure
MIEQEGTFPLPLFIIDLQWFAAEDEGRSEDPTETKLRKAREEGRVPKSQDLNGAFVMLFT
CCCCCCCCCCEEEEEEHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEEEC
STSLFLLAPFILRECIGVLRFFFTRATTASIQNTGWFFVFVRYFMKLALPISFVALVSGV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AANIVQNKTVLFSVKSIRPQFKKISPDVIRFFKRSFFSTEGLFNLLKSLIKITAIFFVSY
HHHHHCCCHHEEEEHHHCHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
FTIRNDLFMFVSLLGVSLTQSIFYITSLAGKVLLEVSLLLVVFSLPDYFFQRRQFIDSLK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MSRQEVKEELKEQEGDPLVRSYVRKQMQSLVRESARNTTDADVVITNPTHFAVAVQYEPA
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCEEEEEEEECCC
YMTAPTVVAKGSDGTAYRIKRLAKEAGILIEENKPLARALYTQVAIGREVPYEYFNALVL
EEECCCEEEECCCCHHHHHHHHHHHCCEEEECCCHHHHHHHHHHHHCCCCCHHHHHHHHH
IFTKLDKFKTHAQRKR
HHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8529894; 9665876