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The map label for this gene is fliR

Identifier: 189025941

GI number: 189025941

Start: 786220

End: 787017

Strand: Reverse

Name: fliR

Synonym: TPASS_0716

Alternate gene names: 189025941

Gene position: 787017-786220 (Counterclockwise)

Preceding gene: 189025942

Following gene: 189025940

Centisome position: 69.07

GC content: 43.73

Gene sequence:

>798_bases
ATGGAACGGTCCTTTGATGCACTCTTTTCTCAGGCTTCTCTTTTTTTTCTTGCGGCGGTCCGCGTGTTTGCGCTTATGTT
TACGGTACCTCTCTTGTCGGTGCGCTCGGTTTCTCGGGTAGTGAGGGTGGCACTCGCAGGCCTGATTGCATTCCTCGTAT
TACCGCTTGCGTACCCTGCACCCATGCAGGTTCGTGAGTTTAGTGCGTACTATGTGCTTTTGTTGCTCGGAGAAGGTTTG
CTGGGGATTTTAACAGGTTTTTTTATTAGCGTAATTTTTACGACTTTTAGTGCGGCAGGACAGTTTTTTTCGTATCAGAT
GGGTTTTGGAACATCTGAGATGTACGATACCTTTGCACAAATAGAAAATCCTTTGATGGGACAGTTTTTGAACTTTGTGG
CGATGCTTGTTTTTTTGCAAATAAAAGGATTTCAAATCCTGTTTTTAGGAGGCGTGCTGCGGAGCTTTCAGGCTGTTAAT
TGCTTTGTTTTTCTGCGGAAACAGGAAGCGCTCCTGCTGTTTTTTACCAAAGCGTTGAGTGCTCTTTTTTTACACGCGAT
GACTATCGCACTGCCTATCATGGGAGCATTGCTGTTAATCCACGTTTCAATGGGTTTATTAACAAAAGCGGCCCCACAAA
TGAATCTACTCTCTGAAGGGCTTCCGCTTACAATCGTAGTTACGTTTGTTTTACTGAGCGTAATTCTTCCTTACATGATA
AACCTGTTTGTTTCTATACTGTTTGGCGGTTTTGAAATGTTTGAGCAGCTCTTGGTAAAGCTTGGAAAAGCCCTATGA

Upstream 100 bases:

>100_bases
CGGTGGGTGGATGCTGACAATGCTGCAGAATTATACCGTAAGGCTGTTTGACATTATCCCTCAGTTAGTGAGGAGTGGAC
CTGTCTAGTGGATATGTGCG

Downstream 100 bases:

>100_bases
TAGAACAAGAAGGAACATTTCCGCTTCCTCTTTTTATTATTGATTTGCAGTGGTTTGCCGCTGAGGATGAAGGGAGGTCA
GAGGATCCTACCGAAACAAA

Product: flagellar biosynthetic protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 265; Mature: 265

Protein sequence:

>265_residues
MERSFDALFSQASLFFLAAVRVFALMFTVPLLSVRSVSRVVRVALAGLIAFLVLPLAYPAPMQVREFSAYYVLLLLGEGL
LGILTGFFISVIFTTFSAAGQFFSYQMGFGTSEMYDTFAQIENPLMGQFLNFVAMLVFLQIKGFQILFLGGVLRSFQAVN
CFVFLRKQEALLLFFTKALSALFLHAMTIALPIMGALLLIHVSMGLLTKAAPQMNLLSEGLPLTIVVTFVLLSVILPYMI
NLFVSILFGGFEMFEQLLVKLGKAL

Sequences:

>Translated_265_residues
MERSFDALFSQASLFFLAAVRVFALMFTVPLLSVRSVSRVVRVALAGLIAFLVLPLAYPAPMQVREFSAYYVLLLLGEGL
LGILTGFFISVIFTTFSAAGQFFSYQMGFGTSEMYDTFAQIENPLMGQFLNFVAMLVFLQIKGFQILFLGGVLRSFQAVN
CFVFLRKQEALLLFFTKALSALFLHAMTIALPIMGALLLIHVSMGLLTKAAPQMNLLSEGLPLTIVVTFVLLSVILPYMI
NLFVSILFGGFEMFEQLLVKLGKAL
>Mature_265_residues
MERSFDALFSQASLFFLAAVRVFALMFTVPLLSVRSVSRVVRVALAGLIAFLVLPLAYPAPMQVREFSAYYVLLLLGEGL
LGILTGFFISVIFTTFSAAGQFFSYQMGFGTSEMYDTFAQIENPLMGQFLNFVAMLVFLQIKGFQILFLGGVLRSFQAVN
CFVFLRKQEALLLFFTKALSALFLHAMTIALPIMGALLLIHVSMGLLTKAAPQMNLLSEGLPLTIVVTFVLLSVILPYMI
NLFVSILFGGFEMFEQLLVKLGKAL

Specific function: Role in flagellar biosynthesis

COG id: COG1684

COG function: function code NU; Flagellar biosynthesis pathway, component FliR

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential). Bacterial flagellum basal body

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fliR/mopE/spaR family

Homologues:

Organism=Escherichia coli, GI1788261, Length=248, Percent_Identity=30.241935483871, Blast_Score=79, Evalue=3e-16,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): FLIR_TREPA (P74932)

Other databases:

- EMBL:   U36839
- EMBL:   AE000520
- PIR:   JC4509
- RefSeq:   NP_219153.1
- ProteinModelPortal:   P74932
- IntAct:   P74932
- MINT:   MINT-6480153
- GeneID:   2610994
- GenomeReviews:   AE000520_GR
- KEGG:   tpa:TP0716
- NMPDR:   fig|243276.1.peg.712
- TIGR:   TP_0716
- HOGENOM:   HBG251050
- OMA:   FATDSHH
- ProtClustDB:   CLSK218828
- BioCyc:   TPAL243276:TP_0716-MONOMER
- InterPro:   IPR006303
- InterPro:   IPR002010
- PRINTS:   PR00953
- TIGRFAMs:   TIGR01400

Pfam domain/function: PF01311 Bac_export_1

EC number: NA

Molecular weight: Translated: 29314; Mature: 29314

Theoretical pI: Translated: 9.41; Mature: 9.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x20dfba98)-; HASH(0x20e11d54)-; HASH(0x1fea9124)-; HASH(0x20e12eb4)-; HASH(0x2157b000)-; HASH(0x1fcafb08)-;

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHCCH
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8529894; 9665876