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The map label for this gene is lysK [H]

Identifier: 189025869

GI number: 189025869

Start: 706897

End: 708483

Strand: Reverse

Name: lysK [H]

Synonym: TPASS_0644

Alternate gene names: 189025869

Gene position: 708483-706897 (Counterclockwise)

Preceding gene: 189025870

Following gene: 189025866

Centisome position: 62.18

GC content: 47.39

Gene sequence:

>1587_bases
ATGAGTATCTGTGAAAAGTCACTTCATTGGGCTGACAAGGTTGCGCACAAGATTATCAAGGAATGTGCTGACTGTGATCA
ATACACCTGTGCATCGGGGATTACCCCCTCAGGAACGGTACATATTGGTAATTTCAGAGAGATTATTTCCGTTGACCTTG
TAGTGCGGGCCCTGCGTGACCAGGGGAAATCAGTGCGCTTTGTACATTCGTGGGACGATTATGACGTTTTTCGTAGGATT
CCCGACAATGTACCTGCTCAAGATGAATTGAAGCAGTATATTCGCATGCCTATCACTTCAGTTCCTGATCCCTTTCAGCA
GGAAGATAGCTACGCGCGGCACCATGAGCGGGAAATTGAATCGGCGCTCCCGGAGGTAGGTATTTATCCTGAATACGTTT
ATCAGTCAAAGCAATACCAGGCGGGGGTATACGCACAGGAAATAAAGATTGCGCTCGACAATCGGCACCGTATTCAAGCG
ATTTTAAACGAATATCGAGATGAGCAGCATAAAATCAGTGGAACGTATTGGCCCGTATCGGTGTTTTGTACAGCGTGCCA
TAAAGACTGCACCACGGTTGATGCGTGGGATAGCCACTGGTGTCTTCAGTATCATTGCGAGTGTGGGCATGGGGAGCAGG
TGGATTTACGCCAGACGTCTGCGGTAAAACTTAGCTGGCGCGTTGATTGGGCTATGCGGTGGAGTAAGGAGCATGTGGTA
TTTGAGCCTGCAGGGAAGGATCATCATTCTCAGGGAGGTTCTTTTGACACTGCGCGTTTAATTTCTGATCACATTTATCA
CTGGCCTGCGCCTGTTTCTTTTCGTTATGATTTTATTGGATTAAAAGGTTTGCCTGGGAAGATGTCTTCGTCCGCGGGAA
AAGTGGTTGGGCTGCGTGATGTGCTTGAAGTATATCAGCCTGAAGTATTGCGATACCTTTTTGTTTCCACACGTCCAAAT
ACCGAGTTTTCCATTAGTTTTGATCTTGATGTTCTTAAGATATACGAGGATTACGATAAAAGTGAGCGTGTTGCGTGGGG
AATACATGCGGCAAAAAGCGAACACGAATTTATGCGGCATAAAAGGATCTACGAATTGTCACAAGTGCGTGGTATGCCGC
CGTGCATTTCGTACCAGGTACCATTCCGGCATGTATGCAATATATTGCAAATTAATTCGGGAGATATTTCTGCAGTGCTC
GCGTTTTTCTCTGATATACACAAAGATCAGATAGAGCGCTTTGTGCGCCGTTGCCAATGTGCGTGGAACTGGATCCGGGA
CGCTGGTGCACCCGATGACTTTAAATTTACCCTGAAAGAAGATGGTGTGCGCGTGCCGCTCTCTGCAGAGATAACTGAAG
CACTGAGACTCATTCGTGATACGCTTGTGCCACGCACTGACGTACTCAGCGAAAAGGAACTTTCTGCTGAGTTGTATGCG
GTTGCCAGACAGATACCTGTTGGCTCGAAGGAACTGTTCACTGCACTATACCAGGTACTGATCGGAAAGAATCAGGGGCC
ACGGCTTGCGGGTTTCATGAAAGTCATCGGTACACAGCGTTTGCACCGCATGCTTAGCGTATACTAA

Upstream 100 bases:

>100_bases
TATTCGGCACTGCCACCTATGTGGAAGTGTAGGATGTGCGCGTGGGAAGTGCGTACTGGCTTGGCTTTAAAAATATTTTG
CGTACCTGTAAGGAAGGATC

Downstream 100 bases:

>100_bases
AACAGCTCCTGGGAACAGTCAGTGCTCGATGCCTGTATCTCCTGTATTAATTTTTTTATGGTGGGGCTTTGTGCATGATT
TACACAGTGTCCGTTTTGTT

Product: lysyl-tRNA synthetase

Products: NA

Alternate protein names: Lysine--tRNA ligase; LysRS [H]

Number of amino acids: Translated: 528; Mature: 527

Protein sequence:

>528_residues
MSICEKSLHWADKVAHKIIKECADCDQYTCASGITPSGTVHIGNFREIISVDLVVRALRDQGKSVRFVHSWDDYDVFRRI
PDNVPAQDELKQYIRMPITSVPDPFQQEDSYARHHEREIESALPEVGIYPEYVYQSKQYQAGVYAQEIKIALDNRHRIQA
ILNEYRDEQHKISGTYWPVSVFCTACHKDCTTVDAWDSHWCLQYHCECGHGEQVDLRQTSAVKLSWRVDWAMRWSKEHVV
FEPAGKDHHSQGGSFDTARLISDHIYHWPAPVSFRYDFIGLKGLPGKMSSSAGKVVGLRDVLEVYQPEVLRYLFVSTRPN
TEFSISFDLDVLKIYEDYDKSERVAWGIHAAKSEHEFMRHKRIYELSQVRGMPPCISYQVPFRHVCNILQINSGDISAVL
AFFSDIHKDQIERFVRRCQCAWNWIRDAGAPDDFKFTLKEDGVRVPLSAEITEALRLIRDTLVPRTDVLSEKELSAELYA
VARQIPVGSKELFTALYQVLIGKNQGPRLAGFMKVIGTQRLHRMLSVY

Sequences:

>Translated_528_residues
MSICEKSLHWADKVAHKIIKECADCDQYTCASGITPSGTVHIGNFREIISVDLVVRALRDQGKSVRFVHSWDDYDVFRRI
PDNVPAQDELKQYIRMPITSVPDPFQQEDSYARHHEREIESALPEVGIYPEYVYQSKQYQAGVYAQEIKIALDNRHRIQA
ILNEYRDEQHKISGTYWPVSVFCTACHKDCTTVDAWDSHWCLQYHCECGHGEQVDLRQTSAVKLSWRVDWAMRWSKEHVV
FEPAGKDHHSQGGSFDTARLISDHIYHWPAPVSFRYDFIGLKGLPGKMSSSAGKVVGLRDVLEVYQPEVLRYLFVSTRPN
TEFSISFDLDVLKIYEDYDKSERVAWGIHAAKSEHEFMRHKRIYELSQVRGMPPCISYQVPFRHVCNILQINSGDISAVL
AFFSDIHKDQIERFVRRCQCAWNWIRDAGAPDDFKFTLKEDGVRVPLSAEITEALRLIRDTLVPRTDVLSEKELSAELYA
VARQIPVGSKELFTALYQVLIGKNQGPRLAGFMKVIGTQRLHRMLSVY
>Mature_527_residues
SICEKSLHWADKVAHKIIKECADCDQYTCASGITPSGTVHIGNFREIISVDLVVRALRDQGKSVRFVHSWDDYDVFRRIP
DNVPAQDELKQYIRMPITSVPDPFQQEDSYARHHEREIESALPEVGIYPEYVYQSKQYQAGVYAQEIKIALDNRHRIQAI
LNEYRDEQHKISGTYWPVSVFCTACHKDCTTVDAWDSHWCLQYHCECGHGEQVDLRQTSAVKLSWRVDWAMRWSKEHVVF
EPAGKDHHSQGGSFDTARLISDHIYHWPAPVSFRYDFIGLKGLPGKMSSSAGKVVGLRDVLEVYQPEVLRYLFVSTRPNT
EFSISFDLDVLKIYEDYDKSERVAWGIHAAKSEHEFMRHKRIYELSQVRGMPPCISYQVPFRHVCNILQINSGDISAVLA
FFSDIHKDQIERFVRRCQCAWNWIRDAGAPDDFKFTLKEDGVRVPLSAEITEALRLIRDTLVPRTDVLSEKELSAELYAV
ARQIPVGSKELFTALYQVLIGKNQGPRLAGFMKVIGTQRLHRMLSVY

Specific function: Unknown

COG id: COG1384

COG function: function code J; Lysyl-tRNA synthetase (class I)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008925
- InterPro:   IPR020751
- InterPro:   IPR001412
- InterPro:   IPR002904
- InterPro:   IPR020754
- InterPro:   IPR020756
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01921 tRNA-synt_1f [H]

EC number: =6.1.1.6 [H]

Molecular weight: Translated: 60849; Mature: 60718

Theoretical pI: Translated: 6.92; Mature: 6.92

Prosite motif: PS00028 ZINC_FINGER_C2H2_1 ; PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSICEKSLHWADKVAHKIIKECADCDQYTCASGITPSGTVHIGNFREIISVDLVVRALRD
CCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHH
QGKSVRFVHSWDDYDVFRRIPDNVPAQDELKQYIRMPITSVPDPFQQEDSYARHHEREIE
CCCEEEEEECCCCHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHH
SALPEVGIYPEYVYQSKQYQAGVYAQEIKIALDNRHRIQAILNEYRDEQHKISGTYWPVS
HHCCCCCCCHHHHHCCCCCCCCCCHHHEEEEECCCHHHHHHHHHHCCHHHHCCCCCCHHH
VFCTACHKDCTTVDAWDSHWCLQYHCECGHGEQVDLRQTSAVKLSWRVDWAMRWSKEHVV
HHHHHHCCCCCCCCCCCCCCEEEEEEECCCCCEEECCCCCEEEEEEEEEEHEEECCCEEE
FEPAGKDHHSQGGSFDTARLISDHIYHWPAPVSFRYDFIGLKGLPGKMSSSAGKVVGLRD
ECCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCEECHHH
VLEVYQPEVLRYLFVSTRPNTEFSISFDLDVLKIYEDYDKSERVAWGIHAAKSEHEFMRH
HHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHH
KRIYELSQVRGMPPCISYQVPFRHVCNILQINSGDISAVLAFFSDIHKDQIERFVRRCQC
HHHHHHHHHCCCCCCEECCCCHHHHCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AWNWIRDAGAPDDFKFTLKEDGVRVPLSAEITEALRLIRDTLVPRTDVLSEKELSAELYA
HHHHHHCCCCCCCEEEEEECCCEECCCHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHH
VARQIPVGSKELFTALYQVLIGKNQGPRLAGFMKVIGTQRLHRMLSVY
HHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SICEKSLHWADKVAHKIIKECADCDQYTCASGITPSGTVHIGNFREIISVDLVVRALRD
CCHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHH
QGKSVRFVHSWDDYDVFRRIPDNVPAQDELKQYIRMPITSVPDPFQQEDSYARHHEREIE
CCCEEEEEECCCCHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHH
SALPEVGIYPEYVYQSKQYQAGVYAQEIKIALDNRHRIQAILNEYRDEQHKISGTYWPVS
HHCCCCCCCHHHHHCCCCCCCCCCHHHEEEEECCCHHHHHHHHHHCCHHHHCCCCCCHHH
VFCTACHKDCTTVDAWDSHWCLQYHCECGHGEQVDLRQTSAVKLSWRVDWAMRWSKEHVV
HHHHHHCCCCCCCCCCCCCCEEEEEEECCCCCEEECCCCCEEEEEEEEEEHEEECCCEEE
FEPAGKDHHSQGGSFDTARLISDHIYHWPAPVSFRYDFIGLKGLPGKMSSSAGKVVGLRD
ECCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCEECHHH
VLEVYQPEVLRYLFVSTRPNTEFSISFDLDVLKIYEDYDKSERVAWGIHAAKSEHEFMRH
HHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHH
KRIYELSQVRGMPPCISYQVPFRHVCNILQINSGDISAVLAFFSDIHKDQIERFVRRCQC
HHHHHHHHHCCCCCCEECCCCHHHHCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AWNWIRDAGAPDDFKFTLKEDGVRVPLSAEITEALRLIRDTLVPRTDVLSEKELSAELYA
HHHHHHCCCCCCCEEEEEECCCEECCCHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHH
VARQIPVGSKELFTALYQVLIGKNQGPRLAGFMKVIGTQRLHRMLSVY
HHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9665876 [H]