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The map label for this gene is lolC [H]

Identifier: 189025809

GI number: 189025809

Start: 633713

End: 635200

Strand: Direct

Name: lolC [H]

Synonym: TPASS_0582

Alternate gene names: 189025809

Gene position: 633713-635200 (Clockwise)

Preceding gene: 189025808

Following gene: 189025811

Centisome position: 55.62

GC content: 50.81

Gene sequence:

>1488_bases
ATGAAACAAAGGTGCGCCGCGGTGAATCTGATTCGAGTTATTTTCATGTGTGCATTACGTTGCGCAGGAGTGTGCGCAGG
ATATGGGCACACCCCATCTCTACACGGTGATGCGCACCACGTACTGCCTACGCCAGTACCTTTTCTATCAGGTACTCCGG
TAGCAGGAAAACGACGTTCCTTTTTGCGCAAAAGTTTTTTCTGTGCCGCGCTCGGCATCGGGATTAGCATCATCCCACTC
ATTGTTGTCCTTGTGGTGTCTGATGGAATGATTGAAGGGATCACCACACGGATGATTGAACTCGGATCGGGTCACCTCCA
GTTTATCGATATACTGCCGCTTGCTCCCAATGAAACGGCAACGCAACGATATGAAGACGCGCAGCGCATATTTAATGCAT
TTATGGCGCAGGACTTTGGCCCATACTGTCACTCACGATGGATGCACCTTCAGGGAGATGGTATTGTAATCGGAAAAACA
GGGCGTGCAGGGGGGAATATCCGCGCAGTTCCCCCTGATTTTTTTTCTAGTGAGCGTGGACTTCGTCCATTTTTAACCGT
CGAAGGTTCACTTGAACTGGTAGATAGGCCGCAGGGAGTACACACGTTAATATTGGGAAAACGCATCGCTGAGCGCATTG
GGGTGCGCTGTGGGGACACGTGCCAGATACTCACCCTCGTGCAAGGAGGGACAGGTCGTGCGGTCCCCAAAATGGTGCGC
GCGGTGGTAGGAGGTATTGTTTCTTGCGGATATCAGGAGCTTGATGCGTTGTGGGTATTTATCCCCCTCACGCTGGGAAT
GAAAATTCTCTCCCCCGCATCTGCGCTACTTTCTTTTGTGGTAAAAACTGCCGACGCGTTTGACGCTAAGGCGATGACTC
GTTTTATTGAGCAAGTACACGAACAATTACCGAGCCATTTTAGTGCGTACACGTGGCAAGACATGAATCGATCGCAATTT
CATTCTTTCCGAACATCACGAAAGTTATTGTTATTCATTATGTATTTGATAGTGCTAGTAGCGTCAGTGCACATCTCTTC
GGTACTGGTGGTGCTAATGACAGAACGGCGTAAAGAAATTGCGATGTTAAAAGCGATGGGCGCTCCTCCCCATGTTATTG
CTTTGATCTTTTTGAGTGCAGGGTTGCTCACGGCGTTGTACGGTTTGCTTATTGGTTTGCCGCTTGGTATGTGGTGCGCG
ATTCACGTAAACGAAATGTTTCTTTTCGCAGAACAGATGCTAAATAGCTGGCGCACAGCGATACACGCCATAGGGCAACT
CTTTTTGCGCACGAGTGCGCACGTGCCGGTGACACCCATTCATCTGTTAGATCCTGCTCACTACCTGGAACGCATTCCCA
TCGTGTTGTCGGTGCACGCGCTCTGTGGCGTTGCAGGAGGCACGCTATGCCTATCGTTGGCGGTATGCATCATTCCTGCG
CTCCGTGCGGGCCGCGTGCGTCCCCTTGACCTCATGCGCAAGGTGTGA

Upstream 100 bases:

>100_bases
AGGAATATCAAAAGACGTTACTCATTGTAACGCACGACCCACGTATTGCATCGATGACCGACTACCGTTACCAGCTACAG
CAGGGAAGTTTGATACGCAT

Downstream 100 bases:

>100_bases
TAGGATGCCCCCAGTTTTTTTGATTTCTTACATCCGGCTCGCAGACGGATGGGTACCATCTTTTAGAAGAGCACTCGGCC
GGTGCGGTAGGGGCTATGGA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 495; Mature: 495

Protein sequence:

>495_residues
MKQRCAAVNLIRVIFMCALRCAGVCAGYGHTPSLHGDAHHVLPTPVPFLSGTPVAGKRRSFLRKSFFCAALGIGISIIPL
IVVLVVSDGMIEGITTRMIELGSGHLQFIDILPLAPNETATQRYEDAQRIFNAFMAQDFGPYCHSRWMHLQGDGIVIGKT
GRAGGNIRAVPPDFFSSERGLRPFLTVEGSLELVDRPQGVHTLILGKRIAERIGVRCGDTCQILTLVQGGTGRAVPKMVR
AVVGGIVSCGYQELDALWVFIPLTLGMKILSPASALLSFVVKTADAFDAKAMTRFIEQVHEQLPSHFSAYTWQDMNRSQF
HSFRTSRKLLLFIMYLIVLVASVHISSVLVVLMTERRKEIAMLKAMGAPPHVIALIFLSAGLLTALYGLLIGLPLGMWCA
IHVNEMFLFAEQMLNSWRTAIHAIGQLFLRTSAHVPVTPIHLLDPAHYLERIPIVLSVHALCGVAGGTLCLSLAVCIIPA
LRAGRVRPLDLMRKV

Sequences:

>Translated_495_residues
MKQRCAAVNLIRVIFMCALRCAGVCAGYGHTPSLHGDAHHVLPTPVPFLSGTPVAGKRRSFLRKSFFCAALGIGISIIPL
IVVLVVSDGMIEGITTRMIELGSGHLQFIDILPLAPNETATQRYEDAQRIFNAFMAQDFGPYCHSRWMHLQGDGIVIGKT
GRAGGNIRAVPPDFFSSERGLRPFLTVEGSLELVDRPQGVHTLILGKRIAERIGVRCGDTCQILTLVQGGTGRAVPKMVR
AVVGGIVSCGYQELDALWVFIPLTLGMKILSPASALLSFVVKTADAFDAKAMTRFIEQVHEQLPSHFSAYTWQDMNRSQF
HSFRTSRKLLLFIMYLIVLVASVHISSVLVVLMTERRKEIAMLKAMGAPPHVIALIFLSAGLLTALYGLLIGLPLGMWCA
IHVNEMFLFAEQMLNSWRTAIHAIGQLFLRTSAHVPVTPIHLLDPAHYLERIPIVLSVHALCGVAGGTLCLSLAVCIIPA
LRAGRVRPLDLMRKV
>Mature_495_residues
MKQRCAAVNLIRVIFMCALRCAGVCAGYGHTPSLHGDAHHVLPTPVPFLSGTPVAGKRRSFLRKSFFCAALGIGISIIPL
IVVLVVSDGMIEGITTRMIELGSGHLQFIDILPLAPNETATQRYEDAQRIFNAFMAQDFGPYCHSRWMHLQGDGIVIGKT
GRAGGNIRAVPPDFFSSERGLRPFLTVEGSLELVDRPQGVHTLILGKRIAERIGVRCGDTCQILTLVQGGTGRAVPKMVR
AVVGGIVSCGYQELDALWVFIPLTLGMKILSPASALLSFVVKTADAFDAKAMTRFIEQVHEQLPSHFSAYTWQDMNRSQF
HSFRTSRKLLLFIMYLIVLVASVHISSVLVVLMTERRKEIAMLKAMGAPPHVIALIFLSAGLLTALYGLLIGLPLGMWCA
IHVNEMFLFAEQMLNSWRTAIHAIGQLFLRTSAHVPVTPIHLLDPAHYLERIPIVLSVHALCGVAGGTLCLSLAVCIIPA
LRAGRVRPLDLMRKV

Specific function: Part of an ATP-dependent transport system responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787362, Length=217, Percent_Identity=26.7281105990783, Blast_Score=79, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 54134; Mature: 54134

Theoretical pI: Translated: 9.51; Mature: 9.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQRCAAVNLIRVIFMCALRCAGVCAGYGHTPSLHGDAHHVLPTPVPFLSGTPVAGKRRS
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHH
FLRKSFFCAALGIGISIIPLIVVLVVSDGMIEGITTRMIELGSGHLQFIDILPLAPNETA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEEEEECCCCCHH
TQRYEDAQRIFNAFMAQDFGPYCHSRWMHLQGDGIVIGKTGRAGGNIRAVPPDFFSSERG
HHHHHHHHHHHHHHHHHHCCHHHHHCCEEEECCEEEEECCCCCCCCCEECCCHHHCCCCC
LRPFLTVEGSLELVDRPQGVHTLILGKRIAERIGVRCGDTCQILTLVQGGTGRAVPKMVR
CCCEEEECCCEEECCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCHHHHHHH
AVVGGIVSCGYQELDALWVFIPLTLGMKILSPASALLSFVVKTADAFDAKAMTRFIEQVH
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
EQLPSHFSAYTWQDMNRSQFHSFRTSRKLLLFIMYLIVLVASVHISSVLVVLMTERRKEI
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AMLKAMGAPPHVIALIFLSAGLLTALYGLLIGLPLGMWCAIHVNEMFLFAEQMLNSWRTA
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IHAIGQLFLRTSAHVPVTPIHLLDPAHYLERIPIVLSVHALCGVAGGTLCLSLAVCIIPA
HHHHHHHHHHCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
LRAGRVRPLDLMRKV
HHCCCCCHHHHHHCC
>Mature Secondary Structure
MKQRCAAVNLIRVIFMCALRCAGVCAGYGHTPSLHGDAHHVLPTPVPFLSGTPVAGKRRS
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHH
FLRKSFFCAALGIGISIIPLIVVLVVSDGMIEGITTRMIELGSGHLQFIDILPLAPNETA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEEEEECCCCCHH
TQRYEDAQRIFNAFMAQDFGPYCHSRWMHLQGDGIVIGKTGRAGGNIRAVPPDFFSSERG
HHHHHHHHHHHHHHHHHHCCHHHHHCCEEEECCEEEEECCCCCCCCCEECCCHHHCCCCC
LRPFLTVEGSLELVDRPQGVHTLILGKRIAERIGVRCGDTCQILTLVQGGTGRAVPKMVR
CCCEEEECCCEEECCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCHHHHHHH
AVVGGIVSCGYQELDALWVFIPLTLGMKILSPASALLSFVVKTADAFDAKAMTRFIEQVH
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
EQLPSHFSAYTWQDMNRSQFHSFRTSRKLLLFIMYLIVLVASVHISSVLVVLMTERRKEI
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AMLKAMGAPPHVIALIFLSAGLLTALYGLLIGLPLGMWCAIHVNEMFLFAEQMLNSWRTA
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IHAIGQLFLRTSAHVPVTPIHLLDPAHYLERIPIVLSVHALCGVAGGTLCLSLAVCIIPA
HHHHHHHHHHCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
LRAGRVRPLDLMRKV
HHCCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]