| Definition | Treponema pallidum subsp. pallidum SS14, complete genome. |
|---|---|
| Accession | NC_010741 |
| Length | 1,139,457 |
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The map label for this gene is clpC [H]
Identifier: 189025777
GI number: 189025777
Start: 594531
End: 596975
Strand: Direct
Name: clpC [H]
Synonym: TPASS_0549
Alternate gene names: 189025777
Gene position: 594531-596975 (Clockwise)
Preceding gene: 189025776
Following gene: 189025781
Centisome position: 52.18
GC content: 55.26
Gene sequence:
>2445_bases GTGTTACAGGACCTATCCGCAAATGCCCGTAAGGTACTGCTCGAGCTCGGTCAGACCGTTGCGCGTGAGGCTCGCGCCTC GCTCCTTCAGCCAGAGCACATTCTGCTCGCCCTCATTCAGCACAAAGTAGGCCGCGGCTACAAGCTCATCGAAAAACTCA TTGAAGATGTCGCTACCGTCCGCCTCATCCTCGAGCAACACGTCCTTACCAATGAGGGAGACGTCGCCAGTCCCCAGGAC CTGCCCGTCTCAGGACGCGTCAAACACTTGCTCGACATCGCAGCAATGGAAGCACGCTCCCTGCGGTGCGCTTACATCGG TACCGAACACCTCGTTATCGCCTTTGCCCGAGAGGAGCAAAATCCTCTCTTCCAAAGCCTCATCCGAGAAGGACTCTCGC TCGATGACCTGCGAAACGCGAGCATTATATCCTCACCTCATTCTGATACCACCCGCACCCGGCTCGAGCGGAAAGTTGCA AGTGTCCTTGACGAATACGGCACCGACCTTACCGAACGCGCGCGCGCCGGCGCCCTCAATCCGGTCATCGGACGAAACAA AGAAATTACCCGCGTCATTCAAATCCTGTGCCGGAGAGGAAAAAATAACCCGGTGCTCATCGGAGAGCCAGGTGTCGGGA AAACTTCCATCGTTGAGGGGCTCGCGTACGCCATCGTTCGGGAGGAGGTCCCGCACATCCTGCTGCACACCCGCGTCGTT TCCCTAGACCTTGCCGCCGTCATAGCAGGAACAAAGTACCGCGGCCAGTTTGAGGAGCGGCTCAAACGCATTATTAAGGA GGTGGAAGAAACTGAAAAAGTCATCCTTTTCATCGATGAGCTGCACACACTCATCGGAGCAGGAGGCACGCAGGGGTCTT TGGACGCCGCCAACATGCTCAAGCCGGCCCTTGCACGCGGACAAATCCAGTGCATTGGGGCAACAACCCTGGCAGAGTAT CGCCGTTACTTTGAAAAAGACGCAGCTCTCACCCGCCGATTCCGATCGGTGCTCGTGCGTGAACCGAGCTTTGAAGAAAC CTGCACTATTTTACGCAAAATAAAATCACACTACGAACGACATCACCAGGTGATATACCAAAGCGATGCGCTTGAAAAAA TTGTTGAGCTTTCACGGCGCTACATCCCTGAGCGGTTCTTTCCAGATAAGGCAATTGATCTTATGGATGAAGTAGGAGCC ATGAAACGGGTACAACAGCGCGCGGATACGCAGGTATTGCGTTCCTTTTCCATAAAAGTTGCTAATCTTACCACAGAGAC TGAGCGCGCCATTGCGCTTGAAGATTGGGCGCGCGCGCGTTCCTTACACACCGATGTGGTGCAGCTGCGCAGACGGCTCC ACGCGCTGAAGGTAGAGTGGAGCGCGCGCGAAGCGCTGTCTATCTTTGCAGAAGATGTTGCACAGGCTGTCTCTCTCATG ACCGATATCCCGGTACATTCGCTCGAAGGGGATGAGCTGTGCCGCTTTACCAATATCGAACGGGATCTTTGTGCCACCGT GCGTGGGCAGCGCGAGGCCATTGCAACGCTCGCGCGCGCTATCGTACGCGCGCGTGTCGGCATCTCTTCAGACACGCGCC CCATTGGCTCCTTCCTGTTTCTTGGACCGACCGGTGTAGGCAAAACGCTCTTGGCAAAGACACTCGCGGAATTTCTTTTC GGTTCAGCAGACGCGCTCATCCGCATTGACATGAGCGACTACATGGAACGCTACAACACCTCACGCCTCATGGGAGCACC GCCTGGATACGTGGGATTTGAAAATGGCGGTCTACTTACCGAGCGCGTACGGCACCGCCCTTTTTCTGTCATCCTTCTGG ATGAAATTGAAAAGGCGCATCCAGATGTCTTCAATGTTCTCCTCCAGGTGTTAGAAGAAGGAGAGCTGCAAGACAACCTG GGGCACACGGTGAACTTCCGCAACACTATCATCATCATGACCAGCAATGCAGGCACACGCGGCCTGGGGGAAAACGTTCC TGGCTTTCAAACCGCACGCGCGCGAAACATCGAGTACCGTCAGCTGCGCGTACAGGCCCTCCGGGAAATAAAACGCATCT TCTCTCCGGAGTTTCTCAATCGCGTTGACGAGTGCGTAGTGTTTGCTCCGCTTGAGCGAGAGACCCTGCAGGAAATTTTA GAATGCGAACTGAAGAAGCTCGCAGAACGCCTACGCGGTAAAGATATTGTGCTGCGCTACAGCGCGGCTGCAAAGGCCTA CTGTCTTGAACACGGCTTTGACCCATTCTTGGGCGCACGCCCCCTGCGCCGCGTATTGCAGCAAGAAATTGAAAATGAGC TTGCGCTGCGCATGATTCACGGAACGTTGCGCGCAGGATCGTGCGTGCACATAGACTCAGACGGCGCGCGCCTCCACCTT TCTACCGAAAAAAGTTACCTGACGCTGCATCCCCAAGAAATATAA
Upstream 100 bases:
>100_bases TAGCCTGCCGTGGCGCACCCCTGCTTTGCTCCACGCCGCGCTCTTTACGTTCCCCGCACACATGCGCTACACTCCCCGCC ACCGCCGCAGGGAGGGCCCC
Downstream 100 bases:
>100_bases CTAATCAGTCACACGCGCCCGTATCTCCCGTACCTGCAGGTCACTTTCCCACACAGAGCTTCTCAAACAGCGCATCTAGG ATATCTTCGCTGTGCACTTC
Product: ATP-dependent Clp protease, subunit C
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 814; Mature: 814
Protein sequence:
>814_residues MLQDLSANARKVLLELGQTVAREARASLLQPEHILLALIQHKVGRGYKLIEKLIEDVATVRLILEQHVLTNEGDVASPQD LPVSGRVKHLLDIAAMEARSLRCAYIGTEHLVIAFAREEQNPLFQSLIREGLSLDDLRNASIISSPHSDTTRTRLERKVA SVLDEYGTDLTERARAGALNPVIGRNKEITRVIQILCRRGKNNPVLIGEPGVGKTSIVEGLAYAIVREEVPHILLHTRVV SLDLAAVIAGTKYRGQFEERLKRIIKEVEETEKVILFIDELHTLIGAGGTQGSLDAANMLKPALARGQIQCIGATTLAEY RRYFEKDAALTRRFRSVLVREPSFEETCTILRKIKSHYERHHQVIYQSDALEKIVELSRRYIPERFFPDKAIDLMDEVGA MKRVQQRADTQVLRSFSIKVANLTTETERAIALEDWARARSLHTDVVQLRRRLHALKVEWSAREALSIFAEDVAQAVSLM TDIPVHSLEGDELCRFTNIERDLCATVRGQREAIATLARAIVRARVGISSDTRPIGSFLFLGPTGVGKTLLAKTLAEFLF GSADALIRIDMSDYMERYNTSRLMGAPPGYVGFENGGLLTERVRHRPFSVILLDEIEKAHPDVFNVLLQVLEEGELQDNL GHTVNFRNTIIIMTSNAGTRGLGENVPGFQTARARNIEYRQLRVQALREIKRIFSPEFLNRVDECVVFAPLERETLQEIL ECELKKLAERLRGKDIVLRYSAAAKAYCLEHGFDPFLGARPLRRVLQQEIENELALRMIHGTLRAGSCVHIDSDGARLHL STEKSYLTLHPQEI
Sequences:
>Translated_814_residues MLQDLSANARKVLLELGQTVAREARASLLQPEHILLALIQHKVGRGYKLIEKLIEDVATVRLILEQHVLTNEGDVASPQD LPVSGRVKHLLDIAAMEARSLRCAYIGTEHLVIAFAREEQNPLFQSLIREGLSLDDLRNASIISSPHSDTTRTRLERKVA SVLDEYGTDLTERARAGALNPVIGRNKEITRVIQILCRRGKNNPVLIGEPGVGKTSIVEGLAYAIVREEVPHILLHTRVV SLDLAAVIAGTKYRGQFEERLKRIIKEVEETEKVILFIDELHTLIGAGGTQGSLDAANMLKPALARGQIQCIGATTLAEY RRYFEKDAALTRRFRSVLVREPSFEETCTILRKIKSHYERHHQVIYQSDALEKIVELSRRYIPERFFPDKAIDLMDEVGA MKRVQQRADTQVLRSFSIKVANLTTETERAIALEDWARARSLHTDVVQLRRRLHALKVEWSAREALSIFAEDVAQAVSLM TDIPVHSLEGDELCRFTNIERDLCATVRGQREAIATLARAIVRARVGISSDTRPIGSFLFLGPTGVGKTLLAKTLAEFLF GSADALIRIDMSDYMERYNTSRLMGAPPGYVGFENGGLLTERVRHRPFSVILLDEIEKAHPDVFNVLLQVLEEGELQDNL GHTVNFRNTIIIMTSNAGTRGLGENVPGFQTARARNIEYRQLRVQALREIKRIFSPEFLNRVDECVVFAPLERETLQEIL ECELKKLAERLRGKDIVLRYSAAAKAYCLEHGFDPFLGARPLRRVLQQEIENELALRMIHGTLRAGSCVHIDSDGARLHL STEKSYLTLHPQEI >Mature_814_residues MLQDLSANARKVLLELGQTVAREARASLLQPEHILLALIQHKVGRGYKLIEKLIEDVATVRLILEQHVLTNEGDVASPQD LPVSGRVKHLLDIAAMEARSLRCAYIGTEHLVIAFAREEQNPLFQSLIREGLSLDDLRNASIISSPHSDTTRTRLERKVA SVLDEYGTDLTERARAGALNPVIGRNKEITRVIQILCRRGKNNPVLIGEPGVGKTSIVEGLAYAIVREEVPHILLHTRVV SLDLAAVIAGTKYRGQFEERLKRIIKEVEETEKVILFIDELHTLIGAGGTQGSLDAANMLKPALARGQIQCIGATTLAEY RRYFEKDAALTRRFRSVLVREPSFEETCTILRKIKSHYERHHQVIYQSDALEKIVELSRRYIPERFFPDKAIDLMDEVGA MKRVQQRADTQVLRSFSIKVANLTTETERAIALEDWARARSLHTDVVQLRRRLHALKVEWSAREALSIFAEDVAQAVSLM TDIPVHSLEGDELCRFTNIERDLCATVRGQREAIATLARAIVRARVGISSDTRPIGSFLFLGPTGVGKTLLAKTLAEFLF GSADALIRIDMSDYMERYNTSRLMGAPPGYVGFENGGLLTERVRHRPFSVILLDEIEKAHPDVFNVLLQVLEEGELQDNL GHTVNFRNTIIIMTSNAGTRGLGENVPGFQTARARNIEYRQLRVQALREIKRIFSPEFLNRVDECVVFAPLERETLQEIL ECELKKLAERLRGKDIVLRYSAAAKAYCLEHGFDPFLGARPLRRVLQQEIENELALRMIHGTLRAGSCVHIDSDGARLHL STEKSYLTLHPQEI
Specific function: Bacterial hemolysins are exotoxins that attack blood cell membranes and cause cell rupture by mechanisms not clearly defined [H]
COG id: COG0542
COG function: function code O; ATPases with chaperone activity, ATP-binding subunit
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 UVR domain [H]
Homologues:
Organism=Homo sapiens, GI13540606, Length=320, Percent_Identity=32.5, Blast_Score=167, Evalue=5e-41, Organism=Escherichia coli, GI1788943, Length=873, Percent_Identity=41.008018327606, Blast_Score=580, Evalue=1e-167, Organism=Escherichia coli, GI1787109, Length=800, Percent_Identity=37.125, Blast_Score=491, Evalue=1e-140, Organism=Saccharomyces cerevisiae, GI6320464, Length=331, Percent_Identity=42.2960725075529, Blast_Score=275, Evalue=2e-74, Organism=Saccharomyces cerevisiae, GI6323002, Length=399, Percent_Identity=39.8496240601504, Blast_Score=266, Evalue=7e-72,
Paralogues:
None
Copy number: 560 Molecules/Cell In: Glucose minimal media [C]
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003593 - InterPro: IPR013093 - InterPro: IPR003959 - InterPro: IPR018368 - InterPro: IPR001270 - InterPro: IPR019489 - InterPro: IPR004176 - InterPro: IPR023150 - InterPro: IPR001943 [H]
Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small; PF02151 UVR [H]
EC number: NA
Molecular weight: Translated: 91584; Mature: 91584
Theoretical pI: Translated: 7.83; Mature: 7.83
Prosite motif: PS00870 CLPAB_1
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.2 %Cys (Translated Protein) 1.4 %Met (Translated Protein) 2.6 %Cys+Met (Translated Protein) 1.2 %Cys (Mature Protein) 1.4 %Met (Mature Protein) 2.6 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MLQDLSANARKVLLELGQTVAREARASLLQPEHILLALIQHKVGRGYKLIEKLIEDVATV CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH RLILEQHVLTNEGDVASPQDLPVSGRVKHLLDIAAMEARSLRCAYIGTEHLVIAFAREEQ HHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCEEEEECCCEEEEEEECCCC NPLFQSLIREGLSLDDLRNASIISSPHSDTTRTRLERKVASVLDEYGTDLTERARAGALN CHHHHHHHHCCCCHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCC PVIGRNKEITRVIQILCRRGKNNPVLIGEPGVGKTSIVEGLAYAIVREEVPHILLHTRVV CCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHH SLDLAAVIAGTKYRGQFEERLKRIIKEVEETEKVILFIDELHTLIGAGGTQGSLDAANML HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHH KPALARGQIQCIGATTLAEYRRYFEKDAALTRRFRSVLVREPSFEETCTILRKIKSHYER HHHHHCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH HHQVIYQSDALEKIVELSRRYIPERFFPDKAIDLMDEVGAMKRVQQRADTQVLRSFSIKV HHHHHHHHHHHHHHHHHHHHHCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEE ANLTTETERAIALEDWARARSLHTDVVQLRRRLHALKVEWSAREALSIFAEDVAQAVSLM EEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH TDIPVHSLEGDELCRFTNIERDLCATVRGQREAIATLARAIVRARVGISSDTRPIGSFLF HCCCCCCCCCCHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEE LGPTGVGKTLLAKTLAEFLFGSADALIRIDMSDYMERYNTSRLMGAPPGYVGFENGGLLT ECCCCCCHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHCCCCCCCCCCCCCCCCCCCCHH ERVRHRPFSVILLDEIEKAHPDVFNVLLQVLEEGELQDNLGHTVNFRNTIIIMTSNAGTR HHHHCCCCEEEEHHHHHHHCCHHHHHHHHHHHCCCCHHCCCCEEEECCEEEEEECCCCCC GLGENVPGFQTARARNIEYRQLRVQALREIKRIFSPEFLNRVDECVVFAPLERETLQEIL CCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHEEEECCCCHHHHHHHH ECELKKLAERLRGKDIVLRYSAAAKAYCLEHGFDPFLGARPLRRVLQQEIENELALRMIH HHHHHHHHHHHCCCCEEEEEHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH GTLRAGSCVHIDSDGARLHLSTEKSYLTLHPQEI HHHCCCCEEEECCCCCEEEEECCCCEEEECCCCC >Mature Secondary Structure MLQDLSANARKVLLELGQTVAREARASLLQPEHILLALIQHKVGRGYKLIEKLIEDVATV CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH RLILEQHVLTNEGDVASPQDLPVSGRVKHLLDIAAMEARSLRCAYIGTEHLVIAFAREEQ HHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCEEEEECCCEEEEEEECCCC NPLFQSLIREGLSLDDLRNASIISSPHSDTTRTRLERKVASVLDEYGTDLTERARAGALN CHHHHHHHHCCCCHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCC PVIGRNKEITRVIQILCRRGKNNPVLIGEPGVGKTSIVEGLAYAIVREEVPHILLHTRVV CCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHH SLDLAAVIAGTKYRGQFEERLKRIIKEVEETEKVILFIDELHTLIGAGGTQGSLDAANML HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHH KPALARGQIQCIGATTLAEYRRYFEKDAALTRRFRSVLVREPSFEETCTILRKIKSHYER HHHHHCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH HHQVIYQSDALEKIVELSRRYIPERFFPDKAIDLMDEVGAMKRVQQRADTQVLRSFSIKV HHHHHHHHHHHHHHHHHHHHHCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEE ANLTTETERAIALEDWARARSLHTDVVQLRRRLHALKVEWSAREALSIFAEDVAQAVSLM EEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH TDIPVHSLEGDELCRFTNIERDLCATVRGQREAIATLARAIVRARVGISSDTRPIGSFLF HCCCCCCCCCCHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEE LGPTGVGKTLLAKTLAEFLFGSADALIRIDMSDYMERYNTSRLMGAPPGYVGFENGGLLT ECCCCCCHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHCCCCCCCCCCCCCCCCCCCCHH ERVRHRPFSVILLDEIEKAHPDVFNVLLQVLEEGELQDNLGHTVNFRNTIIIMTSNAGTR HHHHCCCCEEEEHHHHHHHCCHHHHHHHHHHHCCCCHHCCCCEEEECCEEEEEECCCCCC GLGENVPGFQTARARNIEYRQLRVQALREIKRIFSPEFLNRVDECVVFAPLERETLQEIL CCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHEEEECCCCHHHHHHHH ECELKKLAERLRGKDIVLRYSAAAKAYCLEHGFDPFLGARPLRRVLQQEIENELALRMIH HHHHHHHHHHHCCCCEEEEEHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH GTLRAGSCVHIDSDGARLHLSTEKSYLTLHPQEI HHHCCCCEEEECCCCCEEEEECCCCEEEECCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 7968456 [H]