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The map label for this gene is efp

Identifier: 189025754

GI number: 189025754

Start: 568865

End: 569428

Strand: Direct

Name: efp

Synonym: TPASS_0525

Alternate gene names: 189025754

Gene position: 568865-569428 (Clockwise)

Preceding gene: 189025745

Following gene: 189025755

Centisome position: 49.92

GC content: 49.82

Gene sequence:

>564_bases
ATGATTAGAGGGGGAGATATCGCAAAGGGGACGGTCCTGCTCCATAAAGGTGCTCCGTACCTGGTTGTCGAGCGCGAGTT
CGTAAACCCGGGTAAGGGTGCTGCGTTTGCGCGCGTTAAAATGAAACATCTTCGTGACGGCTCTGTGCTCACTCAGACAG
TTAAGACCTCAGATACAGTCGAAGATGCGGTTGTAGACAGCCACCGCGCTCAGTATCAGTACGATGACGGGGAATGCTTC
GTCTTTATGGATACCCGCAGTTTTGAACAGATTTTCGTTTCCAAAGGGAATGTCCCAGGAAGAGAGCGCTACTTGCGCGA
AGGGGACGAATACGACATCCTAATTTGGAACGGGGAGTCCATTGACATAAAAATTCCCACCAAAATGGTTTTCCGTGTTG
CACACAGCGAGCCGTATCTTAAGGGGGATACCGTCTCTGGCGCCACAAAGCCTGTGACTACCGAAACGGGTCTTGTCGTG
CGCGTTCCCCTATTTATCAAGCAAGGAGAGAAGATCCTGATAAATACAGAGACGAATGAATATCAAGAACGTGTCAATGA
CTAG

Upstream 100 bases:

>100_bases
AATGCCTCCATTCGAGGCCTTTTAAAAAATATACCTGCGCGGTATACTGCGCCCCCGCAGGTCGTGCAAGACGTTTACTA
GGAGATAAGAGAGGAATTAC

Downstream 100 bases:

>100_bases
CGCTTGGTCGCTCCGTCTTTCTGTACTCTCAGCACCGTCCGCGCAGTGCGCGTGCGGACGCTCCCTACCGCCCGTTCGCA
CCACTCCCACTTCTGGTTCT

Product: translation elongation factor P

Products: NA

Alternate protein names: EF-P

Number of amino acids: Translated: 187; Mature: 187

Protein sequence:

>187_residues
MIRGGDIAKGTVLLHKGAPYLVVEREFVNPGKGAAFARVKMKHLRDGSVLTQTVKTSDTVEDAVVDSHRAQYQYDDGECF
VFMDTRSFEQIFVSKGNVPGRERYLREGDEYDILIWNGESIDIKIPTKMVFRVAHSEPYLKGDTVSGATKPVTTETGLVV
RVPLFIKQGEKILINTETNEYQERVND

Sequences:

>Translated_187_residues
MIRGGDIAKGTVLLHKGAPYLVVEREFVNPGKGAAFARVKMKHLRDGSVLTQTVKTSDTVEDAVVDSHRAQYQYDDGECF
VFMDTRSFEQIFVSKGNVPGRERYLREGDEYDILIWNGESIDIKIPTKMVFRVAHSEPYLKGDTVSGATKPVTTETGLVV
RVPLFIKQGEKILINTETNEYQERVND
>Mature_187_residues
MIRGGDIAKGTVLLHKGAPYLVVEREFVNPGKGAAFARVKMKHLRDGSVLTQTVKTSDTVEDAVVDSHRAQYQYDDGECF
VFMDTRSFEQIFVSKGNVPGRERYLREGDEYDILIWNGESIDIKIPTKMVFRVAHSEPYLKGDTVSGATKPVTTETGLVV
RVPLFIKQGEKILINTETNEYQERVND

Specific function: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing t

COG id: COG0231

COG function: function code J; Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the elongation factor P family

Homologues:

Organism=Escherichia coli, GI1790590, Length=180, Percent_Identity=38.3333333333333, Blast_Score=135, Evalue=1e-33,
Organism=Escherichia coli, GI87082061, Length=190, Percent_Identity=28.9473684210526, Blast_Score=91, Evalue=4e-20,

Paralogues:

None

Copy number: 1600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): EFP_TREPA (O83537)

Other databases:

- EMBL:   AE000520
- PIR:   G71312
- RefSeq:   NP_218965.1
- ProteinModelPortal:   O83537
- IntAct:   O83537
- GeneID:   2610753
- GenomeReviews:   AE000520_GR
- KEGG:   tpa:TP0525
- NMPDR:   fig|243276.1.peg.524
- TIGR:   TP_0525
- HOGENOM:   HBG303311
- OMA:   MISSNDF
- ProtClustDB:   PRK00529
- BioCyc:   TPAL243276:TP_0525-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00141
- InterPro:   IPR015365
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR020599
- InterPro:   IPR013185
- InterPro:   IPR001059
- InterPro:   IPR013852
- InterPro:   IPR011768
- InterPro:   IPR014722
- InterPro:   IPR008991
- Gene3D:   G3DSA:2.40.50.140
- Gene3D:   G3DSA:2.30.30.30
- PIRSF:   PIRSF005901
- SMART:   SM00841
- TIGRFAMs:   TIGR00038

Pfam domain/function: PF01132 EFP; PF08207 EFP_N; PF09285 Elong-fact-P_C; SSF50249 Nucleic_acid_OB; SSF50104 Transl_SH3_like

EC number: NA

Molecular weight: Translated: 21043; Mature: 21043

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: PS01275 EFP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRGGDIAKGTVLLHKGAPYLVVEREFVNPGKGAAFARVKMKHLRDGSVLTQTVKTSDTV
CCCCCCCCCCEEEEECCCCEEEEEECCCCCCCCCEEEEEEHHHCCCCCEEEEEECCCCCH
EDAVVDSHRAQYQYDDGECFVFMDTRSFEQIFVSKGNVPGRERYLREGDEYDILIWNGES
HHHHHCCCCCEEEECCCCEEEEEECCCCEEEEEECCCCCHHHHHHHCCCCEEEEEECCCE
IDIKIPTKMVFRVAHSEPYLKGDTVSGATKPVTTETGLVVRVPLFIKQGEKILINTETNE
EEEEECHHHEEEECCCCCCCCCCCCCCCCCCEECCCCEEEEEEEEEECCCEEEEECCCHH
YQERVND
HHHHHCC
>Mature Secondary Structure
MIRGGDIAKGTVLLHKGAPYLVVEREFVNPGKGAAFARVKMKHLRDGSVLTQTVKTSDTV
CCCCCCCCCCEEEEECCCCEEEEEECCCCCCCCCEEEEEEHHHCCCCCEEEEEECCCCCH
EDAVVDSHRAQYQYDDGECFVFMDTRSFEQIFVSKGNVPGRERYLREGDEYDILIWNGES
HHHHHCCCCCEEEECCCCEEEEEECCCCEEEEEECCCCCHHHHHHHCCCCEEEEEECCCE
IDIKIPTKMVFRVAHSEPYLKGDTVSGATKPVTTETGLVVRVPLFIKQGEKILINTETNE
EEEEECHHHEEEECCCCCCCCCCCCCCCCCCEECCCCEEEEEEEEEECCCEEEEECCCHH
YQERVND
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9665876